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The map label for this gene is fabD [H]

Identifier: 75908942

GI number: 75908942

Start: 3369515

End: 3370393

Strand: Direct

Name: fabD [H]

Synonym: Ava_2730

Alternate gene names: 75908942

Gene position: 3369515-3370393 (Clockwise)

Preceding gene: 75908941

Following gene: 75908943

Centisome position: 52.93

GC content: 45.05

Gene sequence:

>879_bases
ATGACAAAAACCGCATGGGTGTTCCCCGGACAAGGTTCTCAAGCACTGGGGATGGGAACAGACTTACTAGATATACCAAC
TGCCAAAGAAAAATTTGCTCAAGCTGAAGCAATCTTAGGTTGGTCTGTAAGCGAAATCTGCCAAAACGAAGAAAAATTAT
CACAGACACTCTACACCCAACCCAGTCTTTATGTAGTAGAGAGTATCCTTGCAGACCTGACAAAAGAACGGGGACACCAG
CCAGATTTAGTTGCTGGTCATAGTTTAGGAGAATACATCGCACTTTATGTTGCTGGCGTTTTTGAGTGGTCGGCTGGTTT
AAAACTAGTCAAGCGACGAGCTGAACTCATGGATAGCGCCGCAGGCGGCATGATGGCGGCTATGATGAATTTTGACCGCG
AACAGTTAGAAACAGTAATTGCCCAGACTCCTGATGTGGTGCTAGCAAACGATAATAGTCCAGCGCAAGTTGTCATATCC
GGTACTCCAGAAGCTGTGCAGACAGTGATGTCCCAAGTCAAAGCCAAGCGTGCTGTCCCGTTGAAAGTTTCGGGTGCATT
TCATTCACACCTGATGAATACAGCTGCTGTGGAGTTCCAAGAAATTCTGGAAACTGTAGAATTTCAACAGGCTAATGTAC
CCGTATTATCGAATGTCGAGCCAGTGCCAGCAGTTGATGCCACAATTTTAAAACAACGCCTCAGCCAACAAATGACTGGT
TCAGTGCGCTGGCGAGAAATTTCTTTAACATTACCAGTCAACGGCATTGAGAAAGTTGTGGAAATCGGCCCCGGCAATGT
ACTAACAGGTTTGATTAAACGCACTACTGCTAATTTAATTTTAAAAAACATCCGCAACGCTGCGGAACTACTAAATTAG

Upstream 100 bases:

>100_bases
AGATAATCAATTAAAAATTCAAAATGCAAAATTCAAAAATTGGATTGTTCATTTTGAATTTTTAATTTTGAATTTTGAAT
TAGAGCGAAGCGACTGACAA

Downstream 100 bases:

>100_bases
ATACTGGGGATTAGTGAAATAGTGCGGCGAGAGGCTTTCCCTTTCTTCGAGACGCTACTCAAAAATTTTTTCCTTTTCAC
CATGCCCCTGTTCGGACTTC

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTKTAWVFPGQGSQALGMGTDLLDIPTAKEKFAQAEAILGWSVSEICQNEEKLSQTLYTQPSLYVVESILADLTKERGHQ
PDLVAGHSLGEYIALYVAGVFEWSAGLKLVKRRAELMDSAAGGMMAAMMNFDREQLETVIAQTPDVVLANDNSPAQVVIS
GTPEAVQTVMSQVKAKRAVPLKVSGAFHSHLMNTAAVEFQEILETVEFQQANVPVLSNVEPVPAVDATILKQRLSQQMTG
SVRWREISLTLPVNGIEKVVEIGPGNVLTGLIKRTTANLILKNIRNAAELLN

Sequences:

>Translated_292_residues
MTKTAWVFPGQGSQALGMGTDLLDIPTAKEKFAQAEAILGWSVSEICQNEEKLSQTLYTQPSLYVVESILADLTKERGHQ
PDLVAGHSLGEYIALYVAGVFEWSAGLKLVKRRAELMDSAAGGMMAAMMNFDREQLETVIAQTPDVVLANDNSPAQVVIS
GTPEAVQTVMSQVKAKRAVPLKVSGAFHSHLMNTAAVEFQEILETVEFQQANVPVLSNVEPVPAVDATILKQRLSQQMTG
SVRWREISLTLPVNGIEKVVEIGPGNVLTGLIKRTTANLILKNIRNAAELLN
>Mature_291_residues
TKTAWVFPGQGSQALGMGTDLLDIPTAKEKFAQAEAILGWSVSEICQNEEKLSQTLYTQPSLYVVESILADLTKERGHQP
DLVAGHSLGEYIALYVAGVFEWSAGLKLVKRRAELMDSAAGGMMAAMMNFDREQLETVIAQTPDVVLANDNSPAQVVISG
TPEAVQTVMSQVKAKRAVPLKVSGAFHSHLMNTAAVEFQEILETVEFQQANVPVLSNVEPVPAVDATILKQRLSQQMTGS
VRWREISLTLPVNGIEKVVEIGPGNVLTGLIKRTTANLILKNIRNAAELLN

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=296, Percent_Identity=32.7702702702703, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI27477045, Length=108, Percent_Identity=37.962962962963, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1787334, Length=292, Percent_Identity=36.3013698630137, Blast_Score=156, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=27.8350515463918, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17550940, Length=286, Percent_Identity=28.6713286713287, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=31.5614617940199, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31650; Mature: 31519

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTAWVFPGQGSQALGMGTDLLDIPTAKEKFAQAEAILGWSVSEICQNEEKLSQTLYTQ
CCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHCC
PSLYVVESILADLTKERGHQPDLVAGHSLGEYIALYVAGVFEWSAGLKLVKRRAELMDSA
CHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGGMMAAMMNFDREQLETVIAQTPDVVLANDNSPAQVVISGTPEAVQTVMSQVKAKRAVP
CCHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHCCCC
LKVSGAFHSHLMNTAAVEFQEILETVEFQQANVPVLSNVEPVPAVDATILKQRLSQQMTG
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SVRWREISLTLPVNGIEKVVEIGPGNVLTGLIKRTTANLILKNIRNAAELLN
CCEEEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKTAWVFPGQGSQALGMGTDLLDIPTAKEKFAQAEAILGWSVSEICQNEEKLSQTLYTQ
CCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHCC
PSLYVVESILADLTKERGHQPDLVAGHSLGEYIALYVAGVFEWSAGLKLVKRRAELMDSA
CHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGGMMAAMMNFDREQLETVIAQTPDVVLANDNSPAQVVISGTPEAVQTVMSQVKAKRAVP
CCHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHCCCC
LKVSGAFHSHLMNTAAVEFQEILETVEFQQANVPVLSNVEPVPAVDATILKQRLSQQMTG
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SVRWREISLTLPVNGIEKVVEIGPGNVLTGLIKRTTANLILKNIRNAAELLN
CCEEEEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]