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The map label for this gene is hetM [H]

Identifier: 75908809

GI number: 75908809

Start: 3216212

End: 3217732

Strand: Direct

Name: hetM [H]

Synonym: Ava_2595

Alternate gene names: 75908809

Gene position: 3216212-3217732 (Clockwise)

Preceding gene: 75908808

Following gene: 75908810

Centisome position: 50.52

GC content: 43.13

Gene sequence:

>1521_bases
ATGAGTCTAAAACAAAATTATAGTGCAGCAGATATTCAAGCTTGGATGATAGCTAATCTAGCTGAATTGTTGGGGGTGGA
TGGTGATGAAATCGATGCTACTGTCAATTTAGAAAGCTATGGTTTAGATTCGGCACAGGCAATGGTTCTAGTTAGTAAAC
TAGAGCAATTGTTGGGATTTCAACCTTCACCTTTATTGTTGTGGCATTACCCTACTATTGAGTCATTGTCTGAACGTTTA
GCTGAAGAGTTGGCAGAACAATCAGAGGAACAAGATACAGATTCTGCTACTGCTAGCCACAGCAATGGTACACCAGTCCT
CGACTTACAAGCTGAGGTGGTTCTTGACCCCACAATTCATCCTGGTGGTGCTATCCCGGTTGATTTTCCGGTAACTCAAC
CTAAGAAAGTATTTCTGACTGGGGGGACTGGGTTTTTAGGCGCTTTCTTAATTCGGGAACTGCTACAGCAAACTCAGGCT
GATGTATATTGTTTGGTACGCGCTGCTGATGCCCAAGCTGGTAAAGCAAAAATCCAAACTAATCTGGAAGGTTACGCGAT
TTGGCAGGAAGAATATGCGTCGAGAATTATTCCTGTTGTTGGTGATTTAGCGGAACCACTTTTGGGTTTAAGTTCCACAC
AGTTCCAGACTTTGGCGGCGGAAATTGACACTATTTATCATAGTGGCGCATTGTTGAATTATGTTTTCCCTTACTCAGCT
TTGAAGGCGGCGAATGTATTGGGAACTCAAGAGGTTTTACGATTGGCTTGCCAAATTAAAGTTAAGCCGGTGCATTATGT
TTCTAGTGTGGCGGTGTTTGAATCACCTGTCTATGCTGGTAAGGTAGTCAAGGAAAGTGATGATTTTAGCCATTGGGAAG
GGATTTTCCTTGGTTATTCCCAAACCAAATGGGTGGCAGAAAAGTTGGTGAAGATTGCGAGCGATCGCGGTTTACCTGTT
ACTATCCATAGACCACCCTTAATTGGTGGAGATAGTGCCACTGGTATCGGTAACACCCACGACTTTATCAATTTGATGGT
TAAGGGTTGTTTGCAAATGAAATGCTTTCCCGATGTAGAGTATATGCTAGATATGTCTCCTGTAGATTATGTCAGCAAAG
CGATTGTGCATCTATCGATGCAAAAGGAATCGCTAGGTAAAGCTTTCCACCTACAACACCCAGAACCAGTATCTTTAAGT
GTCTTAGTTGACTGGGTACGTTCATTTGGCTACGAGATTAAAACCCTTCCCTACGAAGAATGGCAAGCAGAGTTAATTGC
AAATGCCACTTCTGTAGATAATCCCTTATACACCTTGCGTCCTTTCCTCCTAGAACGCTGGTCTGATGAACAACTCACTA
TCCCTGATTTGTACCTCAAAGCCAGAAGACCCCACATTAGCTGTCAAGACACCCTCAAAGCCCTAGCTGGTACTTCTATT
GGTTGCCCACCGATTGATGGCAAATTATTCATGACTTACACAGCTTACTTGATTCAAACTGGGTTCTTGACCTTGGCTTG
A

Upstream 100 bases:

>100_bases
GAAAGATTCATGGTAAACCACCAATTACCAATGACCAATTACCAATTACCAAGATTATAAATCGACAACTTGACTTACTA
AATAATTCGGAGATTTCATA

Downstream 100 bases:

>100_bases
GGAGAAGACGCGATGCCAGTCGCTACAACGGGGGGAACCCCAACGGACAGTTCGCTCAAGTCGGGAAACCCGCCCACGCA
ACTGTCCTCCGCAACGCGCT

Product: thioester reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSLKQNYSAADIQAWMIANLAELLGVDGDEIDATVNLESYGLDSAQAMVLVSKLEQLLGFQPSPLLLWHYPTIESLSERL
AEELAEQSEEQDTDSATASHSNGTPVLDLQAEVVLDPTIHPGGAIPVDFPVTQPKKVFLTGGTGFLGAFLIRELLQQTQA
DVYCLVRAADAQAGKAKIQTNLEGYAIWQEEYASRIIPVVGDLAEPLLGLSSTQFQTLAAEIDTIYHSGALLNYVFPYSA
LKAANVLGTQEVLRLACQIKVKPVHYVSSVAVFESPVYAGKVVKESDDFSHWEGIFLGYSQTKWVAEKLVKIASDRGLPV
TIHRPPLIGGDSATGIGNTHDFINLMVKGCLQMKCFPDVEYMLDMSPVDYVSKAIVHLSMQKESLGKAFHLQHPEPVSLS
VLVDWVRSFGYEIKTLPYEEWQAELIANATSVDNPLYTLRPFLLERWSDEQLTIPDLYLKARRPHISCQDTLKALAGTSI
GCPPIDGKLFMTYTAYLIQTGFLTLA

Sequences:

>Translated_506_residues
MSLKQNYSAADIQAWMIANLAELLGVDGDEIDATVNLESYGLDSAQAMVLVSKLEQLLGFQPSPLLLWHYPTIESLSERL
AEELAEQSEEQDTDSATASHSNGTPVLDLQAEVVLDPTIHPGGAIPVDFPVTQPKKVFLTGGTGFLGAFLIRELLQQTQA
DVYCLVRAADAQAGKAKIQTNLEGYAIWQEEYASRIIPVVGDLAEPLLGLSSTQFQTLAAEIDTIYHSGALLNYVFPYSA
LKAANVLGTQEVLRLACQIKVKPVHYVSSVAVFESPVYAGKVVKESDDFSHWEGIFLGYSQTKWVAEKLVKIASDRGLPV
TIHRPPLIGGDSATGIGNTHDFINLMVKGCLQMKCFPDVEYMLDMSPVDYVSKAIVHLSMQKESLGKAFHLQHPEPVSLS
VLVDWVRSFGYEIKTLPYEEWQAELIANATSVDNPLYTLRPFLLERWSDEQLTIPDLYLKARRPHISCQDTLKALAGTSI
GCPPIDGKLFMTYTAYLIQTGFLTLA
>Mature_505_residues
SLKQNYSAADIQAWMIANLAELLGVDGDEIDATVNLESYGLDSAQAMVLVSKLEQLLGFQPSPLLLWHYPTIESLSERLA
EELAEQSEEQDTDSATASHSNGTPVLDLQAEVVLDPTIHPGGAIPVDFPVTQPKKVFLTGGTGFLGAFLIRELLQQTQAD
VYCLVRAADAQAGKAKIQTNLEGYAIWQEEYASRIIPVVGDLAEPLLGLSSTQFQTLAAEIDTIYHSGALLNYVFPYSAL
KAANVLGTQEVLRLACQIKVKPVHYVSSVAVFESPVYAGKVVKESDDFSHWEGIFLGYSQTKWVAEKLVKIASDRGLPVT
IHRPPLIGGDSATGIGNTHDFINLMVKGCLQMKCFPDVEYMLDMSPVDYVSKAIVHLSMQKESLGKAFHLQHPEPVSLSV
LVDWVRSFGYEIKTLPYEEWQAELIANATSVDNPLYTLRPFLLERWSDEQLTIPDLYLKARRPHISCQDTLKALAGTSIG
CPPIDGKLFMTYTAYLIQTGFLTLA

Specific function: Unknown

COG id: COG3320

COG function: function code Q; Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319591, Length=466, Percent_Identity=30.4721030042918, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI221330327, Length=275, Percent_Identity=29.4545454545455, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI28572029, Length=224, Percent_Identity=29.0178571428571, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19920962, Length=253, Percent_Identity=26.4822134387352, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI78706760, Length=164, Percent_Identity=32.9268292682927, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20129837, Length=225, Percent_Identity=26.2222222222222, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24652250, Length=225, Percent_Identity=26.2222222222222, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24647492, Length=226, Percent_Identity=26.5486725663717, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28572084, Length=292, Percent_Identity=26.7123287671233, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649464, Length=292, Percent_Identity=26.7123287671233, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24647494, Length=131, Percent_Identity=32.824427480916, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009081
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR010080 [H]

Pfam domain/function: PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: NA

Molecular weight: Translated: 55669; Mature: 55538

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50075 ACP_DOMAIN ; PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKQNYSAADIQAWMIANLAELLGVDGDEIDATVNLESYGLDSAQAMVLVSKLEQLLGF
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHCC
QPSPLLLWHYPTIESLSERLAEELAEQSEEQDTDSATASHSNGTPVLDLQAEVVLDPTIH
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEECCCCC
PGGAIPVDFPVTQPKKVFLTGGTGFLGAFLIRELLQQTQADVYCLVRAADAQAGKAKIQT
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEE
NLEGYAIWQEEYASRIIPVVGDLAEPLLGLSSTQFQTLAAEIDTIYHSGALLNYVFPYSA
CCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCCHHH
LKAANVLGTQEVLRLACQIKVKPVHYVSSVAVFESPVYAGKVVKESDDFSHWEGIFLGYS
HHHHHHCCHHHHHHHHHHEEECCHHHHHHHHHHCCCCHHCCEECCCCCCCCCCEEEECCC
QTKWVAEKLVKIASDRGLPVTIHRPPLIGGDSATGIGNTHDFINLMVKGCLQMKCFPDVE
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHH
YMLDMSPVDYVSKAIVHLSMQKESLGKAFHLQHPEPVSLSVLVDWVRSFGYEIKTLPYEE
HHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCEEEECCHHH
WQAELIANATSVDNPLYTLRPFLLERWSDEQLTIPDLYLKARRPHISCQDTLKALAGTSI
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEECCHHHHHCCCCCCCHHHHHHHHHCCCC
GCPPIDGKLFMTYTAYLIQTGFLTLA
CCCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SLKQNYSAADIQAWMIANLAELLGVDGDEIDATVNLESYGLDSAQAMVLVSKLEQLLGF
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHCC
QPSPLLLWHYPTIESLSERLAEELAEQSEEQDTDSATASHSNGTPVLDLQAEVVLDPTIH
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEECCCCC
PGGAIPVDFPVTQPKKVFLTGGTGFLGAFLIRELLQQTQADVYCLVRAADAQAGKAKIQT
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEE
NLEGYAIWQEEYASRIIPVVGDLAEPLLGLSSTQFQTLAAEIDTIYHSGALLNYVFPYSA
CCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCCHHH
LKAANVLGTQEVLRLACQIKVKPVHYVSSVAVFESPVYAGKVVKESDDFSHWEGIFLGYS
HHHHHHCCHHHHHHHHHHEEECCHHHHHHHHHHCCCCHHCCEECCCCCCCCCCEEEECCC
QTKWVAEKLVKIASDRGLPVTIHRPPLIGGDSATGIGNTHDFINLMVKGCLQMKCFPDVE
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHH
YMLDMSPVDYVSKAIVHLSMQKESLGKAFHLQHPEPVSLSVLVDWVRSFGYEIKTLPYEE
HHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCEEEECCHHH
WQAELIANATSVDNPLYTLRPFLLERWSDEQLTIPDLYLKARRPHISCQDTLKALAGTSI
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEECCHHHHHCCCCCCCHHHHHHHHHCCCC
GCPPIDGKLFMTYTAYLIQTGFLTLA
CCCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840 [H]