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The map label for this gene is pksJ [H]

Identifier: 75908805

GI number: 75908805

Start: 3206952

End: 3208787

Strand: Direct

Name: pksJ [H]

Synonym: Ava_2591

Alternate gene names: 75908805

Gene position: 3206952-3208787 (Clockwise)

Preceding gene: 75908804

Following gene: 75908806

Centisome position: 50.38

GC content: 43.46

Gene sequence:

>1836_bases
ATGCTTTTTTATCTCACGCAGAGACGCAGCGAAAAGTTCCTCGAAGCCGGGTTTCCCGGCGTAGGAAACTTTTCAAGACA
GAGGCGCAGAGAGATAAATGAGATACTTTTAGAATTCAAGTATATGACTACACTCACTCAAGTTCGTCCTGCTTCGGTTT
TTGTTGTAAGTGGCGGTGCGAAAGGCATTACGGCGCAATGTGTGATTGAATTGGCGCAGCACCAGCCTTGTCGTTTTATT
CTCCTTGGTCGGTCGGAAGTTATTGAAAGTGAGCCGGATTTTGCTCGTGATTGTGTTGAGGAGTCGGTTTTAAAAAAAGC
GATTATGCAGCACCTGGTGGCGCAAGGGGAAAAGCCTACGCCGATGAGTGTACAGAAGGTTTATCACAAGATTGTTTCTA
GTCGGGAAATTAAGGCGACTTTGGAGGCGATCGCAGCGACGGGGTCACAGGTAGAATATATTGATGTTGATGTGACTAAT
GTGGCTGAGTTACGCCAAAAGTTAGCGGCTGTGGGGAAAATAACAGGTATTATCCACGGTGCGGGTAATTTGGCGGATAA
GTTAATTGAGAAGAAGACAGACCAGGATTTTGAGAAGGTTTACACGGCGAAGGTGCAAGGTTTAGAAAATCTGCTGTCTT
GTGTGGATGCTAATCAGTTAGAACATTTGGTGTTATTTTCCTCGGTGGCTGGTTTTTATGGGAATATGGGGCAATCGGAT
TATGCGATCGCTAATGAAATTCTCAATAAGTCTGCCCATTTAATTAAGAAAAACTATCCCCAGTGTCACGTTGTGGCTAT
CAATTGGGGTGGTTGGGATAGTGGGATGGTGACACCAGAACTGAAAAAAGCTTTTGCAGAACGGGGAATTGATATTATCC
CTGTGGATGTAGGGACAAAGATGCTGGTGAATGAATTACATCCTAGTCACCATGATTCTACACAAGTAGTCATTGGTAGC
CCTATTATCCCCGCACCAGGAAACATTGACCCCCAGTTACGCAGCTATCGCATCCGTCGCCGCATGACTGTAGAGGCTAA
TCCCTTTCTCCTAGACCATGTGATTGCTGGTACTCCAGTATTACCAGCTACCTGTGGGATGTCTTGGATGATTAATGCTT
GTGAGGAGTGTTATCCCGGTTACAGGTATTTCCGTTGTCAAGATTTTAAAATTTTGAAGGGTATTACTTTCAATGACAAG
GTAGCTACCGAACATATTTTAGAAATACAAGAAGTTGCGAAACATGGTTCTGAATCCATTGAATTTCAGACCAAGATACT
CAGCAAGACACCGGAAGGGAAAATTCATTATCACTTCAGCGCTCACATCACCATAGTGCGGGATTTACCACCAGCGCCAG
TGTATGAATCTCTCGACCTCACAGAAGATCATACCATTGGGGCGATCAGTAAAGATTTTTATCAAAAGGGGGGTTTATCC
CTATTTCATGGTACTTCTTTCCAAGAAATCACCAGAGTTTTAAATATCAATTCCCGGAAAATTACTGTTGAATGTTGTTG
GGCAGAAATTCCCCTCGAAGTTCAAGGACAATTCCCCGTCAAATGGCACAATCCGTACGCCACAGATTTGAGTACACAAC
CCCTATGGTTATGGTTGAGTCATGTACATCAAGAAGTATGCTTACCCGGACAAATAACTAAATCAGAACAGTTTCGAGCC
ATCCCTCGCAACAAACCATTTTATGTTTCTTGCGAAATCGAAAACAAAACACCATCTGGTGTCACAGCTGATATCATCTT
GCATGACCGAGAAGGAAAAATCTACTTCCGTATTTACCAAGCGAAAGCAATCATTGCACCGATGAATTTACACTAA

Upstream 100 bases:

>100_bases
CAACCTCTATATCCCTGAAGTCGCTTACGGTTCTCAAGGCCGTGTCACCCTCATCAGTTAATTACTCCGCGTACCTTTGC
GTTCCTCTGCGTTGAGAAAT

Downstream 100 bases:

>100_bases
CCAAAGTCAGAGTTGTGGGGAGCAGGTGATGAATGAAAGTTCAAACTCTTAATCCTCTCTGCGCCTCTGCGTGATAGAAA
TCATCAACCCTGACACACTC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: PKS [H]

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MLFYLTQRRSEKFLEAGFPGVGNFSRQRRREINEILLEFKYMTTLTQVRPASVFVVSGGAKGITAQCVIELAQHQPCRFI
LLGRSEVIESEPDFARDCVEESVLKKAIMQHLVAQGEKPTPMSVQKVYHKIVSSREIKATLEAIAATGSQVEYIDVDVTN
VAELRQKLAAVGKITGIIHGAGNLADKLIEKKTDQDFEKVYTAKVQGLENLLSCVDANQLEHLVLFSSVAGFYGNMGQSD
YAIANEILNKSAHLIKKNYPQCHVVAINWGGWDSGMVTPELKKAFAERGIDIIPVDVGTKMLVNELHPSHHDSTQVVIGS
PIIPAPGNIDPQLRSYRIRRRMTVEANPFLLDHVIAGTPVLPATCGMSWMINACEECYPGYRYFRCQDFKILKGITFNDK
VATEHILEIQEVAKHGSESIEFQTKILSKTPEGKIHYHFSAHITIVRDLPPAPVYESLDLTEDHTIGAISKDFYQKGGLS
LFHGTSFQEITRVLNINSRKITVECCWAEIPLEVQGQFPVKWHNPYATDLSTQPLWLWLSHVHQEVCLPGQITKSEQFRA
IPRNKPFYVSCEIENKTPSGVTADIILHDREGKIYFRIYQAKAIIAPMNLH

Sequences:

>Translated_611_residues
MLFYLTQRRSEKFLEAGFPGVGNFSRQRRREINEILLEFKYMTTLTQVRPASVFVVSGGAKGITAQCVIELAQHQPCRFI
LLGRSEVIESEPDFARDCVEESVLKKAIMQHLVAQGEKPTPMSVQKVYHKIVSSREIKATLEAIAATGSQVEYIDVDVTN
VAELRQKLAAVGKITGIIHGAGNLADKLIEKKTDQDFEKVYTAKVQGLENLLSCVDANQLEHLVLFSSVAGFYGNMGQSD
YAIANEILNKSAHLIKKNYPQCHVVAINWGGWDSGMVTPELKKAFAERGIDIIPVDVGTKMLVNELHPSHHDSTQVVIGS
PIIPAPGNIDPQLRSYRIRRRMTVEANPFLLDHVIAGTPVLPATCGMSWMINACEECYPGYRYFRCQDFKILKGITFNDK
VATEHILEIQEVAKHGSESIEFQTKILSKTPEGKIHYHFSAHITIVRDLPPAPVYESLDLTEDHTIGAISKDFYQKGGLS
LFHGTSFQEITRVLNINSRKITVECCWAEIPLEVQGQFPVKWHNPYATDLSTQPLWLWLSHVHQEVCLPGQITKSEQFRA
IPRNKPFYVSCEIENKTPSGVTADIILHDREGKIYFRIYQAKAIIAPMNLH
>Mature_611_residues
MLFYLTQRRSEKFLEAGFPGVGNFSRQRRREINEILLEFKYMTTLTQVRPASVFVVSGGAKGITAQCVIELAQHQPCRFI
LLGRSEVIESEPDFARDCVEESVLKKAIMQHLVAQGEKPTPMSVQKVYHKIVSSREIKATLEAIAATGSQVEYIDVDVTN
VAELRQKLAAVGKITGIIHGAGNLADKLIEKKTDQDFEKVYTAKVQGLENLLSCVDANQLEHLVLFSSVAGFYGNMGQSD
YAIANEILNKSAHLIKKNYPQCHVVAINWGGWDSGMVTPELKKAFAERGIDIIPVDVGTKMLVNELHPSHHDSTQVVIGS
PIIPAPGNIDPQLRSYRIRRRMTVEANPFLLDHVIAGTPVLPATCGMSWMINACEECYPGYRYFRCQDFKILKGITFNDK
VATEHILEIQEVAKHGSESIEFQTKILSKTPEGKIHYHFSAHITIVRDLPPAPVYESLDLTEDHTIGAISKDFYQKGGLS
LFHGTSFQEITRVLNINSRKITVECCWAEIPLEVQGQFPVKWHNPYATDLSTQPLWLWLSHVHQEVCLPGQITKSEQFRA
IPRNKPFYVSCEIENKTPSGVTADIILHDREGKIYFRIYQAKAIIAPMNLH

Specific function: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 5 acyl carrier domains [H]

Homologues:

Organism=Caenorhabditis elegans, GI17550940, Length=145, Percent_Identity=31.7241379310345, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR000794
- InterPro:   IPR001242
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR013968
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: NA

Molecular weight: Translated: 68621; Mature: 68621

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFYLTQRRSEKFLEAGFPGVGNFSRQRRREINEILLEFKYMTTLTQVRPASVFVVSGGA
CEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
KGITAQCVIELAQHQPCRFILLGRSEVIESEPDFARDCVEESVLKKAIMQHLVAQGEKPT
CCCHHHHHHHHHCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PMSVQKVYHKIVSSREIKATLEAIAATGSQVEYIDVDVTNVAELRQKLAAVGKITGIIHG
CHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHEEEC
AGNLADKLIEKKTDQDFEKVYTAKVQGLENLLSCVDANQLEHLVLFSSVAGFYGNMGQSD
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCH
YAIANEILNKSAHLIKKNYPQCHVVAINWGGWDSGMVTPELKKAFAERGIDIIPVDVGTK
HHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCHH
MLVNELHPSHHDSTQVVIGSPIIPAPGNIDPQLRSYRIRRRMTVEANPFLLDHVIAGTPV
HHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHEEEECCCCHHHHHHHCCCCC
LPATCGMSWMINACEECYPGYRYFRCQDFKILKGITFNDKVATEHILEIQEVAKHGSESI
CHHHCCHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCE
EFQTKILSKTPEGKIHYHFSAHITIVRDLPPAPVYESLDLTEDHTIGAISKDFYQKGGLS
EHHHHHHCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCE
LFHGTSFQEITRVLNINSRKITVECCWAEIPLEVQGQFPVKWHNPYATDLSTQPLWLWLS
EECCCCHHHHHHHHCCCCCEEEEEEEEEECCEEECCCCCEEECCCCCCCCCCCHHHHHHH
HVHQEVCLPGQITKSEQFRAIPRNKPFYVSCEIENKTPSGVTADIILHDREGKIYFRIYQ
HHHHHHCCCCCCCCCCHHCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEEEE
AKAIIAPMNLH
EEEEEEECCCC
>Mature Secondary Structure
MLFYLTQRRSEKFLEAGFPGVGNFSRQRRREINEILLEFKYMTTLTQVRPASVFVVSGGA
CEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
KGITAQCVIELAQHQPCRFILLGRSEVIESEPDFARDCVEESVLKKAIMQHLVAQGEKPT
CCCHHHHHHHHHCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PMSVQKVYHKIVSSREIKATLEAIAATGSQVEYIDVDVTNVAELRQKLAAVGKITGIIHG
CHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHEEEC
AGNLADKLIEKKTDQDFEKVYTAKVQGLENLLSCVDANQLEHLVLFSSVAGFYGNMGQSD
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCH
YAIANEILNKSAHLIKKNYPQCHVVAINWGGWDSGMVTPELKKAFAERGIDIIPVDVGTK
HHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCHH
MLVNELHPSHHDSTQVVIGSPIIPAPGNIDPQLRSYRIRRRMTVEANPFLLDHVIAGTPV
HHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHEEEECCCCHHHHHHHCCCCC
LPATCGMSWMINACEECYPGYRYFRCQDFKILKGITFNDKVATEHILEIQEVAKHGSESI
CHHHCCHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCE
EFQTKILSKTPEGKIHYHFSAHITIVRDLPPAPVYESLDLTEDHTIGAISKDFYQKGGLS
EHHHHHHCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCE
LFHGTSFQEITRVLNINSRKITVECCWAEIPLEVQGQFPVKWHNPYATDLSTQPLWLWLS
EECCCCHHHHHHHHCCCCCEEEEEEEEEECCEEECCCCCEEECCCCCCCCCCCHHHHHHH
HVHQEVCLPGQITKSEQFRAIPRNKPFYVSCEIENKTPSGVTADIILHDREGKIYFRIYQ
HHHHHHCCCCCCCCCCHHCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEEEE
AKAIIAPMNLH
EEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704258; 9384377; 10568751 [H]