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The map label for this gene is tagO [H]

Identifier: 75908298

GI number: 75908298

Start: 2568276

End: 2569322

Strand: Direct

Name: tagO [H]

Synonym: Ava_2077

Alternate gene names: 75908298

Gene position: 2568276-2569322 (Clockwise)

Preceding gene: 75908297

Following gene: 75908299

Centisome position: 40.35

GC content: 46.7

Gene sequence:

>1047_bases
ATGCCTGCTCAGATTTATCATCTGATTGCCTTCTTGGTAGCGGCAGTAGTCGTTCTCTGGACTACGCCCGATGTCAGAAA
AATTGGTATAAAAAGTGGACGTGTTGACCGCCCTGGCGATCGCAAAATCCATGACCGTCCGATGGTGCGTCTGGGAGGAG
TTTCTATCTTCGCAGGTACAATAATCTCCTTAATGGTCGTTTGGTGGCTAGGTGGGTTTAACAATCTCTCACCAGAAAAA
GAATGGCAAATTTGGGGTGTTATCTTAGGTGGTTTAGGCTTTTTTCTCATCGGTCTAGCCGACGATTTATTAACCCTATC
TCCCTTGGGGCGCTTGTTAATACAAATGATTGTTGCGGCTGGTGCATGGAAAGCCGGTGTCAGCATAGATTTCATCAGCA
TCCCCACAATGGGAATTGTTGACCTGAATTTCCTCAGTTTGCCCATCACCGTTATATGGTTGGTAGGCATGGTAAATGCC
ATCAACTGGATTGATGGTCTAGATGGGTTAGCAGCTGGAGTATCGGGAATTGCGGCTGTGGTTATGTTGCTTGTGTCTTT
GTTTATGCACCAACCAGCAGCAGCTTTAATTGCAGCCGCCTTAGCTGGCGCAGCCTTGGGATTTCTCCGTTACAATTTCA
ACCCCGCGCAAATCTTTATGGGTGATGGTGGTTCCTATTTTATGGGCTTCACCTTGGCGGCTGTGGGTGTGATTGGTTTG
GTAAAAATTCCGGCTTTTACAGCTGTTATTTTGCCTTATTTAATTCTGGCAGTTCCCATTGTGGATATGTCAGCCGTGAT
TCTGTCTCGCATCCGCCGAGGGAAATTGCCTTGGGTTGCAGATAAACGCCACCTCCACCACCGATTACTACAAGCTGGTT
TATCTCATCGCTGGACGGTTTTGTTTATTTATTCCTTAACTCTGTGGGTGGGGAGTTTAGCGTTAGTTGTGGCTGGTGTA
CCTAGCAGTATTGCTTACGCTTGTGGTTCAACATCCCTGTTAAGTTACGTTATTTGGCGAGCTTGGAGGGTTTCTCAGCA
AAAGTGA

Upstream 100 bases:

>100_bases
CCCAAATTCCTGACTGATCAGGGTCTGAAATATAGTAAAAATAAGTAGGAAACCTCCCTCATCACATTTTTGTTTCATAA
ACTACTCATTAAAAATACAG

Downstream 100 bases:

>100_bases
AAAGGTAAAAGCAATAAAGTAGTATTAGCATCTTTTGCCTTTTTCCTTAAATTACATGAGTGCAGAAATTATTTGTGTTG
GTACTGAACTGCTTTTAGGT

Product: glycosyl transferase family protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MPAQIYHLIAFLVAAVVVLWTTPDVRKIGIKSGRVDRPGDRKIHDRPMVRLGGVSIFAGTIISLMVVWWLGGFNNLSPEK
EWQIWGVILGGLGFFLIGLADDLLTLSPLGRLLIQMIVAAGAWKAGVSIDFISIPTMGIVDLNFLSLPITVIWLVGMVNA
INWIDGLDGLAAGVSGIAAVVMLLVSLFMHQPAAALIAAALAGAALGFLRYNFNPAQIFMGDGGSYFMGFTLAAVGVIGL
VKIPAFTAVILPYLILAVPIVDMSAVILSRIRRGKLPWVADKRHLHHRLLQAGLSHRWTVLFIYSLTLWVGSLALVVAGV
PSSIAYACGSTSLLSYVIWRAWRVSQQK

Sequences:

>Translated_348_residues
MPAQIYHLIAFLVAAVVVLWTTPDVRKIGIKSGRVDRPGDRKIHDRPMVRLGGVSIFAGTIISLMVVWWLGGFNNLSPEK
EWQIWGVILGGLGFFLIGLADDLLTLSPLGRLLIQMIVAAGAWKAGVSIDFISIPTMGIVDLNFLSLPITVIWLVGMVNA
INWIDGLDGLAAGVSGIAAVVMLLVSLFMHQPAAALIAAALAGAALGFLRYNFNPAQIFMGDGGSYFMGFTLAAVGVIGL
VKIPAFTAVILPYLILAVPIVDMSAVILSRIRRGKLPWVADKRHLHHRLLQAGLSHRWTVLFIYSLTLWVGSLALVVAGV
PSSIAYACGSTSLLSYVIWRAWRVSQQK
>Mature_347_residues
PAQIYHLIAFLVAAVVVLWTTPDVRKIGIKSGRVDRPGDRKIHDRPMVRLGGVSIFAGTIISLMVVWWLGGFNNLSPEKE
WQIWGVILGGLGFFLIGLADDLLTLSPLGRLLIQMIVAAGAWKAGVSIDFISIPTMGIVDLNFLSLPITVIWLVGMVNAI
NWIDGLDGLAAGVSGIAAVVMLLVSLFMHQPAAALIAAALAGAALGFLRYNFNPAQIFMGDGGSYFMGFTLAAVGVIGLV
KIPAFTAVILPYLILAVPIVDMSAVILSRIRRGKLPWVADKRHLHHRLLQAGLSHRWTVLFIYSLTLWVGSLALVVAGVP
SSIAYACGSTSLLSYVIWRAWRVSQQK

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=339, Percent_Identity=28.3185840707965, Blast_Score=95, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 37556; Mature: 37425

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAQIYHLIAFLVAAVVVLWTTPDVRKIGIKSGRVDRPGDRKIHDRPMVRLGGVSIFAGT
CCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHH
IISLMVVWWLGGFNNLSPEKEWQIWGVILGGLGFFLIGLADDLLTLSPLGRLLIQMIVAA
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAWKAGVSIDFISIPTMGIVDLNFLSLPITVIWLVGMVNAINWIDGLDGLAAGVSGIAAV
CCCCCCCEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
VMLLVSLFMHQPAAALIAAALAGAALGFLRYNFNPAQIFMGDGGSYFMGFTLAAVGVIGL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
VKIPAFTAVILPYLILAVPIVDMSAVILSRIRRGKLPWVADKRHLHHRLLQAGLSHRWTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHH
LFIYSLTLWVGSLALVVAGVPSSIAYACGSTSLLSYVIWRAWRVSQQK
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PAQIYHLIAFLVAAVVVLWTTPDVRKIGIKSGRVDRPGDRKIHDRPMVRLGGVSIFAGT
CHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHH
IISLMVVWWLGGFNNLSPEKEWQIWGVILGGLGFFLIGLADDLLTLSPLGRLLIQMIVAA
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAWKAGVSIDFISIPTMGIVDLNFLSLPITVIWLVGMVNAINWIDGLDGLAAGVSGIAAV
CCCCCCCEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
VMLLVSLFMHQPAAALIAAALAGAALGFLRYNFNPAQIFMGDGGSYFMGFTLAAVGVIGL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
VKIPAFTAVILPYLILAVPIVDMSAVILSRIRRGKLPWVADKRHLHHRLLQAGLSHRWTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHH
LFIYSLTLWVGSLALVVAGVPSSIAYACGSTSLLSYVIWRAWRVSQQK
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]