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The map label for this gene is ycgM [C]

Identifier: 75908294

GI number: 75908294

Start: 2564633

End: 2565406

Strand: Direct

Name: ycgM [C]

Synonym: Ava_2073

Alternate gene names: 75908294

Gene position: 2564633-2565406 (Clockwise)

Preceding gene: 75908291

Following gene: 75908297

Centisome position: 40.29

GC content: 45.87

Gene sequence:

>774_bases
ATGGCGCAGCGCTACGTGCGAGTTCAAAATCGGGAAGGTAAGATTTACTATGGGTTGCTACAACTGTCTTTCAATGTGCA
GGTTCTAGATGCTCCACCGTGGCTGCATGGACAACCCACAGACCTAATTTTAGAACCAGATCATTATCAAATTTTGGCTC
CCTGCGCTCCTTCTAAAATTGTCGCAGTGGGCAAAAATTATGCAGATCATGCAGCCGAAATGGGAACGTCAGTTCCAAGT
GAACCACTAATTTTCCTGAAGCCACCAACAACGATTATTGCCTCGGAGACAGAGATTAAATATCCTCTCCAGTCGCAACG
AGTGGATTATGAAGGAGAATTAGCCTTGATCATTGGCGATCGCACTTGTAACTGTACACCAGAGGAAGCCCAAACTAAAA
TTTGGGGTTATACCATTGCCAATGATGTGACAGCGCGGGATTTACAGCGAAAAGATGGGCAATGGACAAGAGCTAAAGGT
TTTGATACTTTCTGCCCATTGGGACCTTGGATTGTCCGCGAATTGAGTCCAGGGGCAAGATTACAGACCTTTCTCAATGA
TGATGCTAATCCCGTACAATCGGCGGGAATTGATCAAATGGTATTTGCCCCTGATTTTTTGGTGTCATATATCAGTCAGG
TGATGACATTGCTTCCCGGAGATGTGATTTTAACGGGTACGCCAGAGGGTGTAGGAGCTTTGCAACAAGGCGATCGCATC
CGTGTAGAAATTGAAGGTATCGGTCGCCTAGAAAACACCGTAGCAGCCCATTAA

Upstream 100 bases:

>100_bases
ATCAATCAACATCTGAGCAACAAGGAACTATAATCTTACCAGTTTTCAATTTGAATCATCATCTCAATCCGCCGAAATAT
CAAGGATATTCATCAAAGTT

Downstream 100 bases:

>100_bases
CTCTAGCGTACCTGCATATAAACAGCATCAGAAATGGCGGGAATTTCTGCGTAACGTCCCAACAAAGAGTTAGCCACACA
ATAGACCACAGCAGCAATGA

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MAQRYVRVQNREGKIYYGLLQLSFNVQVLDAPPWLHGQPTDLILEPDHYQILAPCAPSKIVAVGKNYADHAAEMGTSVPS
EPLIFLKPPTTIIASETEIKYPLQSQRVDYEGELALIIGDRTCNCTPEEAQTKIWGYTIANDVTARDLQRKDGQWTRAKG
FDTFCPLGPWIVRELSPGARLQTFLNDDANPVQSAGIDQMVFAPDFLVSYISQVMTLLPGDVILTGTPEGVGALQQGDRI
RVEIEGIGRLENTVAAH

Sequences:

>Translated_257_residues
MAQRYVRVQNREGKIYYGLLQLSFNVQVLDAPPWLHGQPTDLILEPDHYQILAPCAPSKIVAVGKNYADHAAEMGTSVPS
EPLIFLKPPTTIIASETEIKYPLQSQRVDYEGELALIIGDRTCNCTPEEAQTKIWGYTIANDVTARDLQRKDGQWTRAKG
FDTFCPLGPWIVRELSPGARLQTFLNDDANPVQSAGIDQMVFAPDFLVSYISQVMTLLPGDVILTGTPEGVGALQQGDRI
RVEIEGIGRLENTVAAH
>Mature_256_residues
AQRYVRVQNREGKIYYGLLQLSFNVQVLDAPPWLHGQPTDLILEPDHYQILAPCAPSKIVAVGKNYADHAAEMGTSVPSE
PLIFLKPPTTIIASETEIKYPLQSQRVDYEGELALIIGDRTCNCTPEEAQTKIWGYTIANDVTARDLQRKDGQWTRAKGF
DTFCPLGPWIVRELSPGARLQTFLNDDANPVQSAGIDQMVFAPDFLVSYISQVMTLLPGDVILTGTPEGVGALQQGDRIR
VEIEGIGRLENTVAAH

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=224, Percent_Identity=42.4107142857143, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI40786394, Length=216, Percent_Identity=43.5185185185185, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI215422413, Length=199, Percent_Identity=37.1859296482412, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI66348062, Length=194, Percent_Identity=38.1443298969072, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI13654274, Length=194, Percent_Identity=38.1443298969072, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1787428, Length=195, Percent_Identity=40.5128205128205, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17557057, Length=189, Percent_Identity=37.037037037037, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324161, Length=228, Percent_Identity=34.2105263157895, Blast_Score=119, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28572127, Length=224, Percent_Identity=36.1607142857143, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24663695, Length=211, Percent_Identity=34.5971563981043, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=34.3137254901961, Blast_Score=108, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 28392; Mature: 28260

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRYVRVQNREGKIYYGLLQLSFNVQVLDAPPWLHGQPTDLILEPDHYQILAPCAPSKI
CCCCEEEEECCCCCEEEEEEEEEEEEEEEECCCCCCCCCCCEEECCCCCEEEECCCCCEE
VAVGKNYADHAAEMGTSVPSEPLIFLKPPTTIIASETEIKYPLQSQRVDYEGELALIIGD
EEECCCHHHHHHHHCCCCCCCCEEEECCCCEEEECCCEEECCHHHCCCCCCCCEEEEECC
RTCNCTPEEAQTKIWGYTIANDVTARDLQRKDGQWTRAKGFDTFCPLGPWIVRELSPGAR
CCCCCCCHHHCEEEEEEEECCCCHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHCCCCHH
LQTFLNDDANPVQSAGIDQMVFAPDFLVSYISQVMTLLPGDVILTGTPEGVGALQQGDRI
HHHHHCCCCCHHHHCCCCCEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHCCCCEE
RVEIEGIGRLENTVAAH
EEEEECCCCCCHHHCCC
>Mature Secondary Structure 
AQRYVRVQNREGKIYYGLLQLSFNVQVLDAPPWLHGQPTDLILEPDHYQILAPCAPSKI
CCCEEEEECCCCCEEEEEEEEEEEEEEEECCCCCCCCCCCEEECCCCCEEEECCCCCEE
VAVGKNYADHAAEMGTSVPSEPLIFLKPPTTIIASETEIKYPLQSQRVDYEGELALIIGD
EEECCCHHHHHHHHCCCCCCCCEEEECCCCEEEECCCEEECCHHHCCCCCCCCEEEEECC
RTCNCTPEEAQTKIWGYTIANDVTARDLQRKDGQWTRAKGFDTFCPLGPWIVRELSPGAR
CCCCCCCHHHCEEEEEEEECCCCHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHCCCCHH
LQTFLNDDANPVQSAGIDQMVFAPDFLVSYISQVMTLLPGDVILTGTPEGVGALQQGDRI
HHHHHCCCCCHHHHCCCCCEEECHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHCCCCEE
RVEIEGIGRLENTVAAH
EEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]