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The map label for this gene is hfaC [H]

Identifier: 75676338

GI number: 75676338

Start: 2350344

End: 2352152

Strand: Direct

Name: hfaC [H]

Synonym: Nwi_2153

Alternate gene names: 75676338

Gene position: 2350344-2352152 (Clockwise)

Preceding gene: 75676337

Following gene: 75676347

Centisome position: 69.09

GC content: 66.11

Gene sequence:

>1809_bases
ATGGCGCCGCCGCTCGTCCAGTTGAAGGATATCGCGCTGACGTTCGGCGGCACGCCGCTTTTGTCGGGCGTCGAACTCAC
GGTATCTGAATCCCAGCGGCTCTGCCTGATCGGCCGCAACGGCTCCGGCAAGTCCACGCTCCTGAAGATCGCAGCCGGCC
TCGTCGCGCCCGACAGCGGCAGCCGCTTCGTGCAGCCCGGCGCCACCGTGCGCTATCTGCCGCAGGAGCCGGACTTCGCC
GGATTCGAAACCACGCTGACCTATGTGGAGGCGGGGCTGGGCCCCGGCGACGATCCCTATCAGGCCCGCTATCTGGTCGA
ACAGCTCGGCCTCACCGGCGAGGAAGATCCCGCGCACCTCTCCGGCGGCGAGAGCCGGCGCGCGGCGCTGGCGCGGGTGC
TGGCCCCCTCGCCCGACATCCTGCTGCTGGATGAACCGACCAACCATCTCGATCTCACCACCATCGAATGGCTGGAAGGT
GAGCTCGGCGCGCGGCGCGGCGCGCTGGTGCTCATCAGCCATGACCGCCGCTTCCTGTCCAATCTCTCACGCAGCACCGC
ATGGCTCGACCGCGGCCGTATCAGACAGATCGACCGGGGTTTCGCGAAGTTCGAGGAATGGCGCGACGAGGTGCTGGCCG
AAGAGGAACGCGACCAGCACAAGCTCGATCGCAAGATCGTCGCCGAGGAACACTGGCTGCGTTACGGCGTCTCGGGCAGG
CGCAAGCGCAACGTCAAGCGGCTCGCCGGTCTTCATGAACTGCGCCAGCAGCGCCGCGACTATCGCGGCACGGCGGGCAG
CGCGACCCTCGCCGCTGCGGAGGCCGATAAATCCGGCAAGCTCGTCATCGAGGCCAAAGGCATCAGCAAGCGCTACGGCG
AGCGGACCATCGTCGACGGCTTCTCGATCCGTATCCAGCGCGGCGACCGCATCGGCATCGTCGGCCCCAACGGCGCAGGC
AAGACCACGCTGATCAACATGCTAACGGGAGCCGACACCCCCGACAGCGGCGCCATCCGGCTCGGGGCCAACATCGAGAT
GGCGACGCTCGACCAGCACCGCGAAAGCCTCGATCCGAAATCGACGCTGACGGAGGCGTTGACCGGAGGACGCGGCGATC
ACGTCATGGTCGGCGGCAAGCCGAAGCACGTCGTCAGCTACATGAAGGATTTTCTGTTCGCACAAGAGCAGATGCGCACG
CCGCTCGAGGTGTTGTCCGGCGGCGAACGCGGCCGGCTGATGCTGGCGCGCGCGCTGGCAAAGCCATCCAACCTGCTGGT
GCTGGACGAGCCGACCAACGACCTCGATCTCGAAACGCTCGACGTACTAGAGGACATGCTCGGAGACTACGAGGGCACCG
TGATCCTGATCAGCCACGACCGTGACTTCCTGGATCGCGTCGTGACCTCGGTGATCGTTCCCGAAGGCAATGGCCGCTGG
ATCGAATACGCCGGCGGCTACACCGACATGCTGGCGCAGCGCGGCGCCGACCTCAAGCGCGAGGCGACGAAAGCCGCACC
CGTACCCGAGGCAGGCCGTTCCGCGAAGCCCGCACCGGCTGCTGGCAAGCGGCGGCTCAGTTTCAACGAGAAACACGCGC
TGGAAACGCTCCCGAAATCGATCGAAAAGCTTCAGGCTGAGATGGCCAGGCAACAGCGCCGCCTTGACGATCCCGACCTC
TATGCGAGAGACCGCGCGGCCTTCGATCAGGCCTCCGCAGCGCTGGCCAAAGCGCAGGCGGAGCTGCAACAGGCCGAGGA
TCGCTGGTTAGAGCTGGAAATGCTTCGCGAAGAGATCGAGCAAGCCTGA

Upstream 100 bases:

>100_bases
GCTCGTTCCAGCCGAGGGATCGTTCGGCATTCCTCTCGGCGCTGGACCAGGCCATTCGCCGCATCCGGCGCGCCTGCGCG
GCACGGCAGGGCTGAAGACG

Downstream 100 bases:

>100_bases
GAGCTTAACGCCGCAACCATTTCAGCGCGCCTCGTCCGGCAGCCGCGCCGGTCGCGAACGACGCCTGCAATAGATAGCCG
CCGGTCGGCGCTTCCCAGTC

Product: ABC transporter, ATPase subunit

Products: NA

Alternate protein names: Protein HfaC [H]

Number of amino acids: Translated: 602; Mature: 601

Protein sequence:

>602_residues
MAPPLVQLKDIALTFGGTPLLSGVELTVSESQRLCLIGRNGSGKSTLLKIAAGLVAPDSGSRFVQPGATVRYLPQEPDFA
GFETTLTYVEAGLGPGDDPYQARYLVEQLGLTGEEDPAHLSGGESRRAALARVLAPSPDILLLDEPTNHLDLTTIEWLEG
ELGARRGALVLISHDRRFLSNLSRSTAWLDRGRIRQIDRGFAKFEEWRDEVLAEEERDQHKLDRKIVAEEHWLRYGVSGR
RKRNVKRLAGLHELRQQRRDYRGTAGSATLAAAEADKSGKLVIEAKGISKRYGERTIVDGFSIRIQRGDRIGIVGPNGAG
KTTLINMLTGADTPDSGAIRLGANIEMATLDQHRESLDPKSTLTEALTGGRGDHVMVGGKPKHVVSYMKDFLFAQEQMRT
PLEVLSGGERGRLMLARALAKPSNLLVLDEPTNDLDLETLDVLEDMLGDYEGTVILISHDRDFLDRVVTSVIVPEGNGRW
IEYAGGYTDMLAQRGADLKREATKAAPVPEAGRSAKPAPAAGKRRLSFNEKHALETLPKSIEKLQAEMARQQRRLDDPDL
YARDRAAFDQASAALAKAQAELQQAEDRWLELEMLREEIEQA

Sequences:

>Translated_602_residues
MAPPLVQLKDIALTFGGTPLLSGVELTVSESQRLCLIGRNGSGKSTLLKIAAGLVAPDSGSRFVQPGATVRYLPQEPDFA
GFETTLTYVEAGLGPGDDPYQARYLVEQLGLTGEEDPAHLSGGESRRAALARVLAPSPDILLLDEPTNHLDLTTIEWLEG
ELGARRGALVLISHDRRFLSNLSRSTAWLDRGRIRQIDRGFAKFEEWRDEVLAEEERDQHKLDRKIVAEEHWLRYGVSGR
RKRNVKRLAGLHELRQQRRDYRGTAGSATLAAAEADKSGKLVIEAKGISKRYGERTIVDGFSIRIQRGDRIGIVGPNGAG
KTTLINMLTGADTPDSGAIRLGANIEMATLDQHRESLDPKSTLTEALTGGRGDHVMVGGKPKHVVSYMKDFLFAQEQMRT
PLEVLSGGERGRLMLARALAKPSNLLVLDEPTNDLDLETLDVLEDMLGDYEGTVILISHDRDFLDRVVTSVIVPEGNGRW
IEYAGGYTDMLAQRGADLKREATKAAPVPEAGRSAKPAPAAGKRRLSFNEKHALETLPKSIEKLQAEMARQQRRLDDPDL
YARDRAAFDQASAALAKAQAELQQAEDRWLELEMLREEIEQA
>Mature_601_residues
APPLVQLKDIALTFGGTPLLSGVELTVSESQRLCLIGRNGSGKSTLLKIAAGLVAPDSGSRFVQPGATVRYLPQEPDFAG
FETTLTYVEAGLGPGDDPYQARYLVEQLGLTGEEDPAHLSGGESRRAALARVLAPSPDILLLDEPTNHLDLTTIEWLEGE
LGARRGALVLISHDRRFLSNLSRSTAWLDRGRIRQIDRGFAKFEEWRDEVLAEEERDQHKLDRKIVAEEHWLRYGVSGRR
KRNVKRLAGLHELRQQRRDYRGTAGSATLAAAEADKSGKLVIEAKGISKRYGERTIVDGFSIRIQRGDRIGIVGPNGAGK
TTLINMLTGADTPDSGAIRLGANIEMATLDQHRESLDPKSTLTEALTGGRGDHVMVGGKPKHVVSYMKDFLFAQEQMRTP
LEVLSGGERGRLMLARALAKPSNLLVLDEPTNDLDLETLDVLEDMLGDYEGTVILISHDRDFLDRVVTSVIVPEGNGRWI
EYAGGYTDMLAQRGADLKREATKAAPVPEAGRSAKPAPAAGKRRLSFNEKHALETLPKSIEKLQAEMARQQRRLDDPDLY
ARDRAAFDQASAALAKAQAELQQAEDRWLELEMLREEIEQA

Specific function: Involved in attachment of the holdfast to the cell. The holdfast is a structure that allows the bacteria to firmly adhere to surfaces [H]

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=549, Percent_Identity=27.5045537340619, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI10947137, Length=402, Percent_Identity=28.3582089552239, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI27881506, Length=402, Percent_Identity=28.3582089552239, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI69354671, Length=374, Percent_Identity=28.3422459893048, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI10947135, Length=374, Percent_Identity=28.3422459893048, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI21536376, Length=202, Percent_Identity=31.1881188118812, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4505771, Length=181, Percent_Identity=30.3867403314917, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI9961252, Length=181, Percent_Identity=30.3867403314917, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI9961250, Length=181, Percent_Identity=30.3867403314917, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1787182, Length=634, Percent_Identity=38.1703470031546, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI2367384, Length=513, Percent_Identity=35.8674463937622, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI1787041, Length=540, Percent_Identity=28.7037037037037, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI1789751, Length=649, Percent_Identity=28.1972265023112, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI87081782, Length=473, Percent_Identity=25.7928118393235, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI48994943, Length=590, Percent_Identity=24.9152542372881, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788225, Length=232, Percent_Identity=29.3103448275862, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788165, Length=226, Percent_Identity=28.3185840707965, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787370, Length=215, Percent_Identity=30.6976744186047, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787029, Length=214, Percent_Identity=28.5046728971963, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787712, Length=215, Percent_Identity=29.3023255813954, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081791, Length=206, Percent_Identity=29.126213592233, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081834, Length=203, Percent_Identity=31.5270935960591, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786253, Length=199, Percent_Identity=32.6633165829146, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081709, Length=218, Percent_Identity=26.1467889908257, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787758, Length=196, Percent_Identity=31.1224489795918, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786563, Length=188, Percent_Identity=32.4468085106383, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1789672, Length=212, Percent_Identity=26.8867924528302, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790739, Length=211, Percent_Identity=28.9099526066351, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786319, Length=196, Percent_Identity=30.1020408163265, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI48995001, Length=220, Percent_Identity=26.8181818181818, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787164, Length=188, Percent_Identity=30.8510638297872, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790467, Length=167, Percent_Identity=26.9461077844311, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1788506, Length=213, Percent_Identity=27.6995305164319, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=527, Percent_Identity=28.0834914611006, Blast_Score=159, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17559834, Length=550, Percent_Identity=26.5454545454545, Blast_Score=158, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17555318, Length=519, Percent_Identity=27.5529865125241, Blast_Score=155, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6320874, Length=541, Percent_Identity=25.6931608133087, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6321121, Length=380, Percent_Identity=27.8947368421053, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6323278, Length=350, Percent_Identity=29.7142857142857, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324314, Length=349, Percent_Identity=28.080229226361, Blast_Score=110, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6325030, Length=234, Percent_Identity=28.2051282051282, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320296, Length=127, Percent_Identity=35.4330708661417, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24642252, Length=535, Percent_Identity=28.0373831775701, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI18859989, Length=535, Percent_Identity=28.0373831775701, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24666836, Length=514, Percent_Identity=28.0155642023346, Blast_Score=156, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24641342, Length=524, Percent_Identity=25.381679389313, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI221512771, Length=194, Percent_Identity=31.9587628865979, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24666092, Length=221, Percent_Identity=32.1266968325792, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24643674, Length=209, Percent_Identity=28.2296650717703, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007406 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 66266; Mature: 66135

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00449 ATPASE_A ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPPLVQLKDIALTFGGTPLLSGVELTVSESQRLCLIGRNGSGKSTLLKIAAGLVAPDSG
CCCCCCCHHHEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCC
SRFVQPGATVRYLPQEPDFAGFETTLTYVEAGLGPGDDPYQARYLVEQLGLTGEEDPAHL
CCEECCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
SGGESRRAALARVLAPSPDILLLDEPTNHLDLTTIEWLEGELGARRGALVLISHDRRFLS
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEHHHHHCCCCCCCCEEEEEECCHHHHH
NLSRSTAWLDRGRIRQIDRGFAKFEEWRDEVLAEEERDQHKLDRKIVAEEHWLRYGVSGR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
RKRNVKRLAGLHELRQQRRDYRGTAGSATLAAAEADKSGKLVIEAKGISKRYGERTIVDG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCHHHCCCCEEECC
FSIRIQRGDRIGIVGPNGAGKTTLINMLTGADTPDSGAIRLGANIEMATLDQHRESLDPK
EEEEEECCCEEEEECCCCCCCHHHEEHHHCCCCCCCCCEEECCCEEEHHHHHHHHHCCHH
STLTEALTGGRGDHVMVGGKPKHVVSYMKDFLFAQEQMRTPLEVLSGGERGRLMLARALA
HHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHC
KPSNLLVLDEPTNDLDLETLDVLEDMLGDYEGTVILISHDRDFLDRVVTSVIVPEGNGRW
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHEEEECCCCCE
IEYAGGYTDMLAQRGADLKREATKAAPVPEAGRSAKPAPAAGKRRLSFNEKHALETLPKS
EEECCCHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IEKLQAEMARQQRRLDDPDLYARDRAAFDQASAALAKAQAELQQAEDRWLELEMLREEIE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QA
CC
>Mature Secondary Structure 
APPLVQLKDIALTFGGTPLLSGVELTVSESQRLCLIGRNGSGKSTLLKIAAGLVAPDSG
CCCCCCHHHEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCC
SRFVQPGATVRYLPQEPDFAGFETTLTYVEAGLGPGDDPYQARYLVEQLGLTGEEDPAHL
CCEECCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
SGGESRRAALARVLAPSPDILLLDEPTNHLDLTTIEWLEGELGARRGALVLISHDRRFLS
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEHHHHHCCCCCCCCEEEEEECCHHHHH
NLSRSTAWLDRGRIRQIDRGFAKFEEWRDEVLAEEERDQHKLDRKIVAEEHWLRYGVSGR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
RKRNVKRLAGLHELRQQRRDYRGTAGSATLAAAEADKSGKLVIEAKGISKRYGERTIVDG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCHHHCCCCEEECC
FSIRIQRGDRIGIVGPNGAGKTTLINMLTGADTPDSGAIRLGANIEMATLDQHRESLDPK
EEEEEECCCEEEEECCCCCCCHHHEEHHHCCCCCCCCCEEECCCEEEHHHHHHHHHCCHH
STLTEALTGGRGDHVMVGGKPKHVVSYMKDFLFAQEQMRTPLEVLSGGERGRLMLARALA
HHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHC
KPSNLLVLDEPTNDLDLETLDVLEDMLGDYEGTVILISHDRDFLDRVVTSVIVPEGNGRW
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHEEEECCCCCE
IEYAGGYTDMLAQRGADLKREATKAAPVPEAGRSAKPAPAAGKRRLSFNEKHALETLPKS
EEECCCHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IEKLQAEMARQQRRLDDPDLYARDRAAFDQASAALAKAQAELQQAEDRWLELEMLREEIE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647; 8150261 [H]