Click here to switch to the map view.

The map label for this gene is insF1 [C]

Identifier: 75676306

GI number: 75676306

Start: 2314646

End: 2315551

Strand: Direct

Name: insF1 [C]

Synonym: Nwi_2120

Alternate gene names: 75676306

Gene position: 2314646-2315551 (Clockwise)

Preceding gene: 75676305

Following gene: 75676307

Centisome position: 68.04

GC content: 65.23

Gene sequence:

>906_bases
ATGATCGCCTTCATCGACGGTCACCGAGAGGTCCACGGGGTCGAGCCGATCTGCAGGGTGCTGCCGATCGCCCCCTCGAC
CTACCATGACGACCTCGCCAAGCGCGCCGATCCCACGAAGCTGTCGGCAAGGGCAAAGCGGGACCTGAGGCTGAAGCCTG
AGATCGAGCGCGTCTTCGTCGAGAACTTCGAGGTCTATGGCGTGAGGAAGGTCTGGCGGCAGCTGAACCGGGAGAACATC
CCGGTTGCTCGCTGCACCGTCGAGCGCCTGATGGCTGATCTCGGCCTGCAGGGCGTCATCCGCGGCAAGCCGATCCGCAC
GACCGTGCAGGACAAGGCAGCTCCGTGCCCGCTCGATCACGTGAACCGGGTCTTCCACGCGCCAGCTCCAAACATGTTGT
GGCTATCCGACTTCACCTACGTGAGCACCTGGTCGGGCTTCGTCTATGTCGCCTTCGTGATCGATGCCTATGCTCGCAGG
ATCGTCGGCTGGCGCGTCAGCCGCGCAGCTCATGCCGCCTTCGTGTTGGACGCCTTGGAGCAGGCGCTGCATGAACGGCG
CCCCGCCAGCAAGGCTGGTCTCGTCCATCACTCGGATCGCGGTTCGCAATACGTCAGCATCCGCTACACCGAGCGCCTGG
CCGAGGCGGGCATCGAGCCTTCGGTCGGCAGCGTCGGCGACAGCTACGACAACGCGCTCGCCGAAACGATCAACGGTCTA
TACAAGGCCGAGGTCATCCATCGGCGCGGGCCGTGGCGGAGCTTCGAGGCGGTCGAGTTCGCCACACTCGCCTGGGTCGA
CTGGTTCAACCATCGCCGGCTGCTGGAGCCCATCGGCAACATCCCGCCGGCCGAAGCCGAGGAGCGCTACTACGCCATGC
TCGACGAGACAGCCATGGCGGCGTGA

Upstream 100 bases:

>100_bases
CGCTGGAGCGGGAGAACCGTGAGCTTCGGCAGGCGAACGAGATCCTGCGCAAGGCGTCGGCGTATTTTGCGATGGCGGAG
CTCGACCGCCGGTCAAAGAC

Downstream 100 bases:

>100_bases
CTCAAACCAAACAGCCTCCGGCAAACTCGGGGCGGTTCAACCCCTTCTAGCGGGGAGACCCCGCAACGCCCCCTATAGAG
AGTGAGAGTGCGGACCGGGT

Product: integrase, catalytic region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MIAFIDGHREVHGVEPICRVLPIAPSTYHDDLAKRADPTKLSARAKRDLRLKPEIERVFVENFEVYGVRKVWRQLNRENI
PVARCTVERLMADLGLQGVIRGKPIRTTVQDKAAPCPLDHVNRVFHAPAPNMLWLSDFTYVSTWSGFVYVAFVIDAYARR
IVGWRVSRAAHAAFVLDALEQALHERRPASKAGLVHHSDRGSQYVSIRYTERLAEAGIEPSVGSVGDSYDNALAETINGL
YKAEVIHRRGPWRSFEAVEFATLAWVDWFNHRRLLEPIGNIPPAEAEERYYAMLDETAMAA

Sequences:

>Translated_301_residues
MIAFIDGHREVHGVEPICRVLPIAPSTYHDDLAKRADPTKLSARAKRDLRLKPEIERVFVENFEVYGVRKVWRQLNRENI
PVARCTVERLMADLGLQGVIRGKPIRTTVQDKAAPCPLDHVNRVFHAPAPNMLWLSDFTYVSTWSGFVYVAFVIDAYARR
IVGWRVSRAAHAAFVLDALEQALHERRPASKAGLVHHSDRGSQYVSIRYTERLAEAGIEPSVGSVGDSYDNALAETINGL
YKAEVIHRRGPWRSFEAVEFATLAWVDWFNHRRLLEPIGNIPPAEAEERYYAMLDETAMAA
>Mature_301_residues
MIAFIDGHREVHGVEPICRVLPIAPSTYHDDLAKRADPTKLSARAKRDLRLKPEIERVFVENFEVYGVRKVWRQLNRENI
PVARCTVERLMADLGLQGVIRGKPIRTTVQDKAAPCPLDHVNRVFHAPAPNMLWLSDFTYVSTWSGFVYVAFVIDAYARR
IVGWRVSRAAHAAFVLDALEQALHERRPASKAGLVHHSDRGSQYVSIRYTERLAEAGIEPSVGSVGDSYDNALAETINGL
YKAEVIHRRGPWRSFEAVEFATLAWVDWFNHRRLLEPIGNIPPAEAEERYYAMLDETAMAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=249, Percent_Identity=54.2168674698795, Blast_Score=256, Evalue=1e-68,
Organism=Escherichia coli, GI1788405, Length=249, Percent_Identity=30.1204819277108, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787263, Length=249, Percent_Identity=30.1204819277108, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786753, Length=249, Percent_Identity=30.1204819277108, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786570, Length=249, Percent_Identity=30.1204819277108, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786490, Length=249, Percent_Identity=30.1204819277108, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789981, Length=283, Percent_Identity=27.208480565371, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 34112; Mature: 34112

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAFIDGHREVHGVEPICRVLPIAPSTYHDDLAKRADPTKLSARAKRDLRLKPEIERVFV
CEEEEECCCHHCCCCHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHH
ENFEVYGVRKVWRQLNRENIPVARCTVERLMADLGLQGVIRGKPIRTTVQDKAAPCPLDH
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHCCCCCCCHHH
VNRVFHAPAPNMLWLSDFTYVSTWSGFVYVAFVIDAYARRIVGWRVSRAAHAAFVLDALE
HHHHHCCCCCCEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALHERRPASKAGLVHHSDRGSQYVSIRYTERLAEAGIEPSVGSVGDSYDNALAETINGL
HHHHHCCCCCCCCCEEECCCCCEEEEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
YKAEVIHRRGPWRSFEAVEFATLAWVDWFNHRRLLEPIGNIPPAEAEERYYAMLDETAMA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure
MIAFIDGHREVHGVEPICRVLPIAPSTYHDDLAKRADPTKLSARAKRDLRLKPEIERVFV
CEEEEECCCHHCCCCHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHH
ENFEVYGVRKVWRQLNRENIPVARCTVERLMADLGLQGVIRGKPIRTTVQDKAAPCPLDH
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHCCCCCCCHHH
VNRVFHAPAPNMLWLSDFTYVSTWSGFVYVAFVIDAYARRIVGWRVSRAAHAAFVLDALE
HHHHHCCCCCCEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALHERRPASKAGLVHHSDRGSQYVSIRYTERLAEAGIEPSVGSVGDSYDNALAETINGL
HHHHHCCCCCCCCCEEECCCCCEEEEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
YKAEVIHRRGPWRSFEAVEFATLAWVDWFNHRRLLEPIGNIPPAEAEERYYAMLDETAMA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]