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The map label for this gene is 75676256

Identifier: 75676256

GI number: 75676256

Start: 2256915

End: 2258285

Strand: Direct

Name: 75676256

Synonym: Nwi_2067

Alternate gene names: NA

Gene position: 2256915-2258285 (Clockwise)

Preceding gene: 75676251

Following gene: 75676258

Centisome position: 66.34

GC content: 62.29

Gene sequence:

>1371_bases
GTGAAGAAATTGCTTATCTCTTTGCTTGCCATCGCATTCGTTGCCGCCATCGCGGGAGTGGGCGTGATCCTGTTCTCGAA
GGAACAGGCGACCGTTGCGCTCGAGGAGCAGTACGGTTCTGATCCGAAACTTCCTCCGCCGGACCCGCGCATTCTGCCGA
CCGTGAACCAGGCCAGGGCCGAGCCGTGGAAGCGAGGCGAAACGCCGACCGCCGCTCAAGGCTATGCGGTGTCCCAGTTC
GCCGATGGACTTGATCATCCGCGCTGGCTGCATGTGCTGCCGAACGGTGACGTGCTTGTCGCGGAAAGCAACAAGCCGCC
CCAGGATGAAAGCAGCATGGGCATCCGCCGCTGGGTGGCGAAGCTCGTGATGAGCAGCGCAGGCGCCAGCACGCCCAGCG
CGAATCGCATCTCCATCCTGCGCGACGCGGACGGCGACGGCGTAGCGGAGTTAAGGCAGCCCTTCATCACCGGACTGTTC
TCACCTTTCGGCATGGCGCTGCTCGATGGCAAGCTCTATGTCGCCAACGCCAACTGCATCGTGGCCTTTCCTTATCAGGA
AGGCGCAACGGAAATCACCGCGAAGCCGGAAACAATTACCGAGCTGCCCGCCGGGCTGAATCACCATTGGACAAAGGACG
TCATCGCATCCCCAGACGGAACGAAGCTCTATGTCACCGTCGGCTCCAACAGCAATGTCGGCGAGAACGGCATGGAGGCG
GAGGAAGGCCGCGCGGCCGTCCATGAAATCGACCTGGCCACAAAGCAGAAGCGCCTGTTTGCCACGGGGCTGCGCAATCC
TAACGGGCTCTCCTGGCAACCCGACAGCGGCGAACTGTGGGTGGTGGTCAACGAGCGCGACGAGATCGGCAGCGATCTCG
TGCCGGACTACATGACCTCAGTGAAGGAGGGTGCATTCTATGGCTGGCCATACAGCTATTTCGGACAGCACGTCGACGAT
CGCATAGAACCGCGTCGACCTGACCTGGTCGCGAAGGCCATCAAGCCGGACTATGCACTCGGCTCCCATACGGCCGCGCT
TGGCCTCACCTTCAATAGCGGAAGCCTGTTCGGGCCTGAAATGAAGAACGGCGCGTTCATCGGCCAGCATGGATCATGGA
ATCGTATGCCGCGCAGCGGTTACAAGGTGATCTTCGTGCCGTTCAGCGACGGCAAGCCCGCCGGACCTCCGCGGGATATC
CTGACCGGATTCCTGCGTCTTGATGAGAGCGCGGCAGGCCGCCCCGTTGGCGTTGCTGTCGCCCGCGATGGGGCGCTGCT
GGTGGCGGACGATGTCGGCAACAGTATCTGGCGGGTGACGCCGAGCCAATCCGGCCAGACAAACCCCGGAAGCGTCGGGT
CGGAACCATAG

Upstream 100 bases:

>100_bases
GTGGCTTTCAACGGTTTTCCGCCGATGCCTTTCGGTGACAGAGCGGCAACGGAACGGCTGACGATGGCGGGCGTTGAGCC
TCGAAAGAGGACACCCTGAC

Downstream 100 bases:

>100_bases
TGATCGCTTCGCGCAATAACTGCTGCGAGCCCGGTCACGCGTCAACTCACGATGAGAACATTATGATGTCTGAGATGTTG
AGGATCAGCCGACCCGCGAC

Product: putative L-sorbosone dehydrogenase (SNDH)

Products: NA

Alternate protein names: SNDH [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MKKLLISLLAIAFVAAIAGVGVILFSKEQATVALEEQYGSDPKLPPPDPRILPTVNQARAEPWKRGETPTAAQGYAVSQF
ADGLDHPRWLHVLPNGDVLVAESNKPPQDESSMGIRRWVAKLVMSSAGASTPSANRISILRDADGDGVAELRQPFITGLF
SPFGMALLDGKLYVANANCIVAFPYQEGATEITAKPETITELPAGLNHHWTKDVIASPDGTKLYVTVGSNSNVGENGMEA
EEGRAAVHEIDLATKQKRLFATGLRNPNGLSWQPDSGELWVVVNERDEIGSDLVPDYMTSVKEGAFYGWPYSYFGQHVDD
RIEPRRPDLVAKAIKPDYALGSHTAALGLTFNSGSLFGPEMKNGAFIGQHGSWNRMPRSGYKVIFVPFSDGKPAGPPRDI
LTGFLRLDESAAGRPVGVAVARDGALLVADDVGNSIWRVTPSQSGQTNPGSVGSEP

Sequences:

>Translated_456_residues
MKKLLISLLAIAFVAAIAGVGVILFSKEQATVALEEQYGSDPKLPPPDPRILPTVNQARAEPWKRGETPTAAQGYAVSQF
ADGLDHPRWLHVLPNGDVLVAESNKPPQDESSMGIRRWVAKLVMSSAGASTPSANRISILRDADGDGVAELRQPFITGLF
SPFGMALLDGKLYVANANCIVAFPYQEGATEITAKPETITELPAGLNHHWTKDVIASPDGTKLYVTVGSNSNVGENGMEA
EEGRAAVHEIDLATKQKRLFATGLRNPNGLSWQPDSGELWVVVNERDEIGSDLVPDYMTSVKEGAFYGWPYSYFGQHVDD
RIEPRRPDLVAKAIKPDYALGSHTAALGLTFNSGSLFGPEMKNGAFIGQHGSWNRMPRSGYKVIFVPFSDGKPAGPPRDI
LTGFLRLDESAAGRPVGVAVARDGALLVADDVGNSIWRVTPSQSGQTNPGSVGSEP
>Mature_456_residues
MKKLLISLLAIAFVAAIAGVGVILFSKEQATVALEEQYGSDPKLPPPDPRILPTVNQARAEPWKRGETPTAAQGYAVSQF
ADGLDHPRWLHVLPNGDVLVAESNKPPQDESSMGIRRWVAKLVMSSAGASTPSANRISILRDADGDGVAELRQPFITGLF
SPFGMALLDGKLYVANANCIVAFPYQEGATEITAKPETITELPAGLNHHWTKDVIASPDGTKLYVTVGSNSNVGENGMEA
EEGRAAVHEIDLATKQKRLFATGLRNPNGLSWQPDSGELWVVVNERDEIGSDLVPDYMTSVKEGAFYGWPYSYFGQHVDD
RIEPRRPDLVAKAIKPDYALGSHTAALGLTFNSGSLFGPEMKNGAFIGQHGSWNRMPRSGYKVIFVPFSDGKPAGPPRDI
LTGFLRLDESAAGRPVGVAVARDGALLVADDVGNSIWRVTPSQSGQTNPGSVGSEP

Specific function: Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA) [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.burgdorferi BB024 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 48909; Mature: 48909

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLISLLAIAFVAAIAGVGVILFSKEQATVALEEQYGSDPKLPPPDPRILPTVNQARA
CHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEHHHCCCCCCCCCCCCCEECCCHHHHC
EPWKRGETPTAAQGYAVSQFADGLDHPRWLHVLPNGDVLVAESNKPPQDESSMGIRRWVA
CHHHCCCCCCCCCCEEHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHH
KLVMSSAGASTPSANRISILRDADGDGVAELRQPFITGLFSPFGMALLDGKLYVANANCI
HHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEECCEEEEEECCEE
VAFPYQEGATEITAKPETITELPAGLNHHWTKDVIASPDGTKLYVTVGSNSNVGENGMEA
EEECCCCCCCEEEECCCHHHHCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCC
EEGRAAVHEIDLATKQKRLFATGLRNPNGLSWQPDSGELWVVVNERDEIGSDLVPDYMTS
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHCCCCCCHHHHHH
VKEGAFYGWPYSYFGQHVDDRIEPRRPDLVAKAIKPDYALGSHTAALGLTFNSGSLFGPE
HHCCCEECCCHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCEECCC
MKNGAFIGQHGSWNRMPRSGYKVIFVPFSDGKPAGPPRDILTGFLRLDESAAGRPVGVAV
CCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEE
ARDGALLVADDVGNSIWRVTPSQSGQTNPGSVGSEP
ECCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKLLISLLAIAFVAAIAGVGVILFSKEQATVALEEQYGSDPKLPPPDPRILPTVNQARA
CHHHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEHHHCCCCCCCCCCCCCEECCCHHHHC
EPWKRGETPTAAQGYAVSQFADGLDHPRWLHVLPNGDVLVAESNKPPQDESSMGIRRWVA
CHHHCCCCCCCCCCEEHHHHHHCCCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHH
KLVMSSAGASTPSANRISILRDADGDGVAELRQPFITGLFSPFGMALLDGKLYVANANCI
HHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEECCEEEEEECCEE
VAFPYQEGATEITAKPETITELPAGLNHHWTKDVIASPDGTKLYVTVGSNSNVGENGMEA
EEECCCCCCCEEEECCCHHHHCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCC
EEGRAAVHEIDLATKQKRLFATGLRNPNGLSWQPDSGELWVVVNERDEIGSDLVPDYMTS
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHCCCCCCHHHHHH
VKEGAFYGWPYSYFGQHVDDRIEPRRPDLVAKAIKPDYALGSHTAALGLTFNSGSLFGPE
HHCCCEECCCHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCEECCC
MKNGAFIGQHGSWNRMPRSGYKVIFVPFSDGKPAGPPRDILTGFLRLDESAAGRPVGVAV
CCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEE
ARDGALLVADDVGNSIWRVTPSQSGQTNPGSVGSEP
ECCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7574579 [H]