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The map label for this gene is 75676116

Identifier: 75676116

GI number: 75676116

Start: 2110844

End: 2111521

Strand: Direct

Name: 75676116

Synonym: Nwi_1925

Alternate gene names: NA

Gene position: 2110844-2111521 (Clockwise)

Preceding gene: 75676115

Following gene: 75676121

Centisome position: 62.05

GC content: 65.93

Gene sequence:

>678_bases
ATGACGACGACTTTGAGGACTGAAACGCGCCGATCCGGCGCGACTCCCCCCGAGCCAGGCCGCGATTGCCCGCTGTGCCC
ACGGCTGGTCGACTATCGCCTTGCGGTTCGGACGCGCGAGCCGGAATGGTTCAACGCACCCGTGCCTTCTTTCGGCGAAC
CCGACTCGGCGGTTCTGATCGTCGGCCTGGCGCCGGGCGTGCAAGGCGCCAACCGCACCGGGCGACCCTTCACCGGCGAC
TACGCCGGCGACCTGCTTTACGCGACGCTTCTCAAATACGGATTCGCCGCCGGACGCTATCAGGCCCGACCCGACGACGG
ACTCAAACTGATCGATTGCCGCATCAGCAACGCGGTGCGTTGCGTGCCACCGCAGAACAAGCCTCTGCCGGCCGAGATCA
ACACCTGCCGCGCGTTCCTTAGCGCCACGCTCGCGGCCATGCCCCGATTACAAGCGGTTGTCGCACTCGGCCGTGTCGCG
CACGATTCCGCGGTGAAAGCGCTCGGCGTTCGCGCCGCTGCCGCCCCCTTCGCTCACGGCGCGGTGCATCATATCGGCGC
GGTCACGCTCTATGACAGCTACCACTGCTCCCGCTACAACACCAACACGCGTGTCCTGACGCCCGAAATGTTCGAGAGCG
TCTTCGCAAAAGTGCGCGCCGATCTGACCTGTCGCTGA

Upstream 100 bases:

>100_bases
GAATTGCAGCCGAAGCTCGGCCGCGACCCGTCGGAACGCCAGTCCCGCCACCACGCACCGCAGTTCCTGCAGCGCGCCAC
CGCCGTGGCGCCCCGGAGCG

Downstream 100 bases:

>100_bases
AGCGCGGGCTATGGCGAACCGGTACCCACTTCGCTCGAAAGCGCTATAGAACTCCGCTCCTGATCCCATCGGAAGCGAAA
GGGCTTTCTCGGCTATCCCT

Product: uracil-DNA glycosylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTTTLRTETRRSGATPPEPGRDCPLCPRLVDYRLAVRTREPEWFNAPVPSFGEPDSAVLIVGLAPGVQGANRTGRPFTGD
YAGDLLYATLLKYGFAAGRYQARPDDGLKLIDCRISNAVRCVPPQNKPLPAEINTCRAFLSATLAAMPRLQAVVALGRVA
HDSAVKALGVRAAAAPFAHGAVHHIGAVTLYDSYHCSRYNTNTRVLTPEMFESVFAKVRADLTCR

Sequences:

>Translated_225_residues
MTTTLRTETRRSGATPPEPGRDCPLCPRLVDYRLAVRTREPEWFNAPVPSFGEPDSAVLIVGLAPGVQGANRTGRPFTGD
YAGDLLYATLLKYGFAAGRYQARPDDGLKLIDCRISNAVRCVPPQNKPLPAEINTCRAFLSATLAAMPRLQAVVALGRVA
HDSAVKALGVRAAAAPFAHGAVHHIGAVTLYDSYHCSRYNTNTRVLTPEMFESVFAKVRADLTCR
>Mature_224_residues
TTTLRTETRRSGATPPEPGRDCPLCPRLVDYRLAVRTREPEWFNAPVPSFGEPDSAVLIVGLAPGVQGANRTGRPFTGDY
AGDLLYATLLKYGFAAGRYQARPDDGLKLIDCRISNAVRCVPPQNKPLPAEINTCRAFLSATLAAMPRLQAVVALGRVAH
DSAVKALGVRAAAAPFAHGAVHHIGAVTLYDSYHCSRYNTNTRVLTPEMFESVFAKVRADLTCR

Specific function: Unknown

COG id: COG1573

COG function: function code L; Uracil-DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1105 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: NA

Molecular weight: Translated: 24366; Mature: 24235

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTLRTETRRSGATPPEPGRDCPLCPRLVDYRLAVRTREPEWFNAPVPSFGEPDSAVLI
CCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEE
VGLAPGVQGANRTGRPFTGDYAGDLLYATLLKYGFAAGRYQARPDDGLKLIDCRISNAVR
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEE
CVPPQNKPLPAEINTCRAFLSATLAAMPRLQAVVALGRVAHDSAVKALGVRAAAAPFAHG
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AVHHIGAVTLYDSYHCSRYNTNTRVLTPEMFESVFAKVRADLTCR
HHHHHEEEEEECCCCCCEECCCCEEECHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTTLRTETRRSGATPPEPGRDCPLCPRLVDYRLAVRTREPEWFNAPVPSFGEPDSAVLI
CCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEE
VGLAPGVQGANRTGRPFTGDYAGDLLYATLLKYGFAAGRYQARPDDGLKLIDCRISNAVR
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEE
CVPPQNKPLPAEINTCRAFLSATLAAMPRLQAVVALGRVAHDSAVKALGVRAAAAPFAHG
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AVHHIGAVTLYDSYHCSRYNTNTRVLTPEMFESVFAKVRADLTCR
HHHHHEEEEEECCCCCCEECCCCEEECHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]