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The map label for this gene is moaC [H]

Identifier: 75676030

GI number: 75676030

Start: 2013188

End: 2013697

Strand: Direct

Name: moaC [H]

Synonym: Nwi_1839

Alternate gene names: 75676030

Gene position: 2013188-2013697 (Clockwise)

Preceding gene: 75676029

Following gene: 75676031

Centisome position: 59.17

GC content: 62.55

Gene sequence:

>510_bases
ATGGCAGACAAGAAAAACAAACCCGCCCTCACCCACATCGACGTCAAAGGCGAGGCGCGGATGGTCGATGTCTCGGCAAA
GCCCGCAACCGAACGCGTCGCCGTTGCCGAAGGCCAGGTCGTCATGACCAAGGCGACGCTGGCCCTGATCGAAAGCGGCA
ACGCCAAGAAAGGCGACGTGCTCGGCACCGCGCGCATCGCCGGCATCATGGCCGCCAAGCGCACTTCGGAACTGATCCCG
CTCTGTCATCCGCTGGCGCTGTCGAAAGTCACGCTCGATATCGAGACCGACAAGAAGATTCCCGGCTGCCGGGTGCGCGC
CAGCGTCAAGGTTTCCGGCCCGACCGGCGTGGAGATGGAAGCCCTCACCGCGGTCTCCGTCGCCTGCCTGACGATCTACG
ACATGATCAAGGCCGTGGAACGCGGCGTTCGTATCGAGGGCATTCATCTGGTCGAGAAGAAGGGCGGCAAGTCCGGCCAC
TATCTCGTGACGGATAACGCTCCAGAATGA

Upstream 100 bases:

>100_bases
GCCTTCACTTCCGATGGAATTCCATGATTCTAATTTGACGCGTTTTCTTCACGCGAACCGGTATCCACTTCGCTTGAGAA
CGCTATAGGATTTGATTGAT

Downstream 100 bases:

>100_bases
TAAGTGACCGGCGTGAACGCGCCGTCGGGCGACATCCGGCTCATCGCACCGTTGTATGCGAGCCGAAAGTTCGGTAGATG
ATTGACGCGCCCGCCAGGCG

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MADKKNKPALTHIDVKGEARMVDVSAKPATERVAVAEGQVVMTKATLALIESGNAKKGDVLGTARIAGIMAAKRTSELIP
LCHPLALSKVTLDIETDKKIPGCRVRASVKVSGPTGVEMEALTAVSVACLTIYDMIKAVERGVRIEGIHLVEKKGGKSGH
YLVTDNAPE

Sequences:

>Translated_169_residues
MADKKNKPALTHIDVKGEARMVDVSAKPATERVAVAEGQVVMTKATLALIESGNAKKGDVLGTARIAGIMAAKRTSELIP
LCHPLALSKVTLDIETDKKIPGCRVRASVKVSGPTGVEMEALTAVSVACLTIYDMIKAVERGVRIEGIHLVEKKGGKSGH
YLVTDNAPE
>Mature_168_residues
ADKKNKPALTHIDVKGEARMVDVSAKPATERVAVAEGQVVMTKATLALIESGNAKKGDVLGTARIAGIMAAKRTSELIPL
CHPLALSKVTLDIETDKKIPGCRVRASVKVSGPTGVEMEALTAVSVACLTIYDMIKAVERGVRIEGIHLVEKKGGKSGHY
LVTDNAPE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=154, Percent_Identity=56.4935064935065, Blast_Score=160, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI32566331, Length=157, Percent_Identity=43.312101910828, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28574490, Length=153, Percent_Identity=52.9411764705882, Blast_Score=149, Evalue=6e-37,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=54.014598540146, Blast_Score=134, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17839; Mature: 17708

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKNKPALTHIDVKGEARMVDVSAKPATERVAVAEGQVVMTKATLALIESGNAKKGDV
CCCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEECCCCEEEEEEEEEEEECCCCCCCCE
LGTARIAGIMAAKRTSELIPLCHPLALSKVTLDIETDKKIPGCRVRASVKVSGPTGVEME
EEHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEEEECCCCCCCHH
ALTAVSVACLTIYDMIKAVERGVRIEGIHLVEKKGGKSGHYLVTDNAPE
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEEECCCCC
>Mature Secondary Structure 
ADKKNKPALTHIDVKGEARMVDVSAKPATERVAVAEGQVVMTKATLALIESGNAKKGDV
CCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEECCCCEEEEEEEEEEEECCCCCCCCE
LGTARIAGIMAAKRTSELIPLCHPLALSKVTLDIETDKKIPGCRVRASVKVSGPTGVEME
EEHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEEEECCCCCCCHH
ALTAVSVACLTIYDMIKAVERGVRIEGIHLVEKKGGKSGHYLVTDNAPE
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9061023; 12597275 [H]