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The map label for this gene is yheS [H]

Identifier: 75675865

GI number: 75675865

Start: 1823066

End: 1824943

Strand: Direct

Name: yheS [H]

Synonym: Nwi_1673

Alternate gene names: 75675865

Gene position: 1823066-1824943 (Clockwise)

Preceding gene: 75675863

Following gene: 75675869

Centisome position: 53.59

GC content: 63.58

Gene sequence:

>1878_bases
ATGCTATCCATCACCGATATTTCGATCCGCATCGCCGGACGCCTGCTGATCGACCATAGCTCCGTTCAGATCGTGCCCGG
CGCGCGCGTCGGCTTCGTGGGACGTAACGGCGTCGGCAAATCGACGCTGTTCCACGCGATACGCGGTGAACTGCCGACGG
AAACCGGCACCATCGCCATTCCGCCGCGCTGGCGCGTGGGCAGCCTTGCGCAGGAGGCGCCGGATGGTCCGGAAAGCCTG
ATCGAGGTGGTGCTTAAGGCCGACCTCGAACGCCATGCGCTGCTGCGTGAAGCCGAAACGGCCCGCGATCCGGAACGTAT
CGCGGACATCCAGATGCGTCTGGTCGATATCGACGCTCATTCTGCGCCCGCACGGGCGGCATCGATCCTGAGCGGTCTCG
GATTTTCAACGGCGGACCAGTCCCGCCCCTGTTCGGAATTCTCAGGCGGCTGGCGCATGCGCGTCGCGCTCGCGGCAACG
CTTTTCGCATCACCCGACCTGCTGCTGCTGGACGAGCCGACCAACTACCTCGATCTCGAAGGAACGCTCTGGCTGGAAGA
TCACCTCGCGCACTACCCGCGCACGGTCATCATCATCAGTCACGACCGCGACCTCCTTGACACATCCGTCGATCAGATTC
TGCATCTCGATCGCGGCAAGCTCTCGCTCTACAAGGGAACCTATTCTGCTTTCGAAGAGCAACGCGCAACTCGCGAGTTG
CTGGACGCCAAGCACGCCAGACGGCAGGCCGATGAGCGCAAGCGGCTCCAGGCCTTCGTGGATCGCTTCAAGGCTAAGGC
CTCGAAGGCGCGCCAGGCGCAGTCACGCGTGAAAATGCTCGAACGCATGAAGCCTGTGACCGCGCTGGTCACACAGGATG
TGCGCGAGATTTCCTTTCCCGTGCCGGACAAGCTGCTATCGCCGCCGATCATCGCCGTTGACGAGGCCGTCGTCGGTTAC
GATCCGCAATCGCCTATTCTCAAGCGCGTGACGTTGCGGGTCGATGAGGACGATCGCATCGCCCTGCTCGGCGCCAACGG
CAACGGCAAGTCCACCCTCGTCAAGCTGCTGGCCGGCAAGCTGCAACCGTTCGCCGGCAGGGTGGTGCGCGCCGACAAGC
TGTCGATCGGCTATTTCGCCCAGCATCAGACCGACGAGCTGGATCTCGACGGCTCGCCCTACGATCATGTGCGGCGCCTG
ATGCAGGATGCTCCGGAAACGAAAATCCGCGCTCGCGTGGGCGGCATCGGCTTTTCCGGCAAGGCGGGCGATACGCTCGT
TCGCAGCCTTTCGGGCGGCGAAAAAGCGCGTCTTCTGCTCGGGCTCGCGACGTTCTTCGCTCCCAACATGATCATCCTCG
ACGAGCCGACCAACCATCTCGATATCGACAGCCGCGCCGCGCTTGCCGAAGCCATCAACGAGTATCCCGGCGCTGTCATC
ATGGTCTCGCACGACCGTTACCTGATCGAGGCCTGCGCCGACCAGCTATGGGTGGTGGCGGACCATACCGTCACTCCTTA
CGACGGCGATCTCGAGGATTACCGCCGCGCGGTTTTATCGGCACGGGGTCTCCGCTCGAATGGCCGCGACCGGGTGTCCG
GCCAGCGCGACGATGGTCGAGACAAGCCGCGGCGCGAGAGGACCGAACGACGCTCGCCGCTCAAACAGAAGATCACGGCC
GCCGAGGCCGAGATCGAGCGAATTACCGGAATCATCGCAAAAATCGATGTCGCCCTTGCCCTGCCGGACCTGTTCAAGCG
TGAGCCCAAACAGGCGGCGCAACTCACCAAGGCGCGCGCCAGCGCGGCCGATGCGCTGCGGCGGGCGGAAGAGGCATGGC
TGGAGGCCAGTTCGTCTTACGATAACGCTACAGGCTGA

Upstream 100 bases:

>100_bases
TCGGCTGTGAATCCTTCTTCGGTCAATGCCCGCCGCCGGCCTCCCTCCTTCGTTCACAAACGAGTTGCGTTTGGCGACGC
AGCGGTGAAAAAAACAAAAC

Downstream 100 bases:

>100_bases
CGGAAAGCCGCCTCCAGAACTGGAGCCTTTCCGGTTTTGACGGGTCGAAAGCATGGCTTTCGATGTTGTTTTGACGCGTT
ATCTTGAAGCGAACAGGTCA

Product: ABC transporter, ATPase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MLSITDISIRIAGRLLIDHSSVQIVPGARVGFVGRNGVGKSTLFHAIRGELPTETGTIAIPPRWRVGSLAQEAPDGPESL
IEVVLKADLERHALLREAETARDPERIADIQMRLVDIDAHSAPARAASILSGLGFSTADQSRPCSEFSGGWRMRVALAAT
LFASPDLLLLDEPTNYLDLEGTLWLEDHLAHYPRTVIIISHDRDLLDTSVDQILHLDRGKLSLYKGTYSAFEEQRATREL
LDAKHARRQADERKRLQAFVDRFKAKASKARQAQSRVKMLERMKPVTALVTQDVREISFPVPDKLLSPPIIAVDEAVVGY
DPQSPILKRVTLRVDEDDRIALLGANGNGKSTLVKLLAGKLQPFAGRVVRADKLSIGYFAQHQTDELDLDGSPYDHVRRL
MQDAPETKIRARVGGIGFSGKAGDTLVRSLSGGEKARLLLGLATFFAPNMIILDEPTNHLDIDSRAALAEAINEYPGAVI
MVSHDRYLIEACADQLWVVADHTVTPYDGDLEDYRRAVLSARGLRSNGRDRVSGQRDDGRDKPRRERTERRSPLKQKITA
AEAEIERITGIIAKIDVALALPDLFKREPKQAAQLTKARASAADALRRAEEAWLEASSSYDNATG

Sequences:

>Translated_625_residues
MLSITDISIRIAGRLLIDHSSVQIVPGARVGFVGRNGVGKSTLFHAIRGELPTETGTIAIPPRWRVGSLAQEAPDGPESL
IEVVLKADLERHALLREAETARDPERIADIQMRLVDIDAHSAPARAASILSGLGFSTADQSRPCSEFSGGWRMRVALAAT
LFASPDLLLLDEPTNYLDLEGTLWLEDHLAHYPRTVIIISHDRDLLDTSVDQILHLDRGKLSLYKGTYSAFEEQRATREL
LDAKHARRQADERKRLQAFVDRFKAKASKARQAQSRVKMLERMKPVTALVTQDVREISFPVPDKLLSPPIIAVDEAVVGY
DPQSPILKRVTLRVDEDDRIALLGANGNGKSTLVKLLAGKLQPFAGRVVRADKLSIGYFAQHQTDELDLDGSPYDHVRRL
MQDAPETKIRARVGGIGFSGKAGDTLVRSLSGGEKARLLLGLATFFAPNMIILDEPTNHLDIDSRAALAEAINEYPGAVI
MVSHDRYLIEACADQLWVVADHTVTPYDGDLEDYRRAVLSARGLRSNGRDRVSGQRDDGRDKPRRERTERRSPLKQKITA
AEAEIERITGIIAKIDVALALPDLFKREPKQAAQLTKARASAADALRRAEEAWLEASSSYDNATG
>Mature_625_residues
MLSITDISIRIAGRLLIDHSSVQIVPGARVGFVGRNGVGKSTLFHAIRGELPTETGTIAIPPRWRVGSLAQEAPDGPESL
IEVVLKADLERHALLREAETARDPERIADIQMRLVDIDAHSAPARAASILSGLGFSTADQSRPCSEFSGGWRMRVALAAT
LFASPDLLLLDEPTNYLDLEGTLWLEDHLAHYPRTVIIISHDRDLLDTSVDQILHLDRGKLSLYKGTYSAFEEQRATREL
LDAKHARRQADERKRLQAFVDRFKAKASKARQAQSRVKMLERMKPVTALVTQDVREISFPVPDKLLSPPIIAVDEAVVGY
DPQSPILKRVTLRVDEDDRIALLGANGNGKSTLVKLLAGKLQPFAGRVVRADKLSIGYFAQHQTDELDLDGSPYDHVRRL
MQDAPETKIRARVGGIGFSGKAGDTLVRSLSGGEKARLLLGLATFFAPNMIILDEPTNHLDIDSRAALAEAINEYPGAVI
MVSHDRYLIEACADQLWVVADHTVTPYDGDLEDYRRAVLSARGLRSNGRDRVSGQRDDGRDKPRRERTERRSPLKQKITA
AEAEIERITGIIAKIDVALALPDLFKREPKQAAQLTKARASAADALRRAEEAWLEASSSYDNATG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=524, Percent_Identity=38.5496183206107, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI27881506, Length=533, Percent_Identity=36.9606003752345, Blast_Score=335, Evalue=6e-92,
Organism=Homo sapiens, GI10947137, Length=533, Percent_Identity=36.9606003752345, Blast_Score=335, Evalue=9e-92,
Organism=Homo sapiens, GI10947135, Length=550, Percent_Identity=37.0909090909091, Blast_Score=301, Evalue=1e-81,
Organism=Homo sapiens, GI69354671, Length=550, Percent_Identity=37.0909090909091, Blast_Score=301, Evalue=2e-81,
Organism=Escherichia coli, GI1789751, Length=634, Percent_Identity=42.2712933753943, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1787041, Length=537, Percent_Identity=35.5679702048417, Blast_Score=311, Evalue=9e-86,
Organism=Escherichia coli, GI1787182, Length=618, Percent_Identity=29.9352750809061, Blast_Score=229, Evalue=5e-61,
Organism=Escherichia coli, GI2367384, Length=539, Percent_Identity=31.3543599257885, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1788165, Length=202, Percent_Identity=31.6831683168317, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI48994943, Length=340, Percent_Identity=25, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787759, Length=218, Percent_Identity=28.8990825688073, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=537, Percent_Identity=37.8026070763501, Blast_Score=348, Evalue=4e-96,
Organism=Caenorhabditis elegans, GI17559834, Length=560, Percent_Identity=36.9642857142857, Blast_Score=343, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI17555318, Length=527, Percent_Identity=36.2428842504744, Blast_Score=328, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI71983523, Length=187, Percent_Identity=32.0855614973262, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=187, Percent_Identity=32.0855614973262, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=187, Percent_Identity=32.0855614973262, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=543, Percent_Identity=38.121546961326, Blast_Score=351, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6320874, Length=530, Percent_Identity=34.3396226415094, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6325030, Length=383, Percent_Identity=30.2872062663185, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6323278, Length=413, Percent_Identity=26.3922518159806, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6324314, Length=416, Percent_Identity=26.4423076923077, Blast_Score=123, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24666836, Length=530, Percent_Identity=38.3018867924528, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24642252, Length=529, Percent_Identity=38.3742911153119, Blast_Score=349, Evalue=4e-96,
Organism=Drosophila melanogaster, GI18859989, Length=529, Percent_Identity=38.3742911153119, Blast_Score=349, Evalue=4e-96,
Organism=Drosophila melanogaster, GI24641342, Length=542, Percent_Identity=36.90036900369, Blast_Score=346, Evalue=3e-95,
Organism=Drosophila melanogaster, GI161077321, Length=259, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 68919; Mature: 68919

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSITDISIRIAGRLLIDHSSVQIVPGARVGFVGRNGVGKSTLFHAIRGELPTETGTIAI
CCEEEEEEEEEEEEEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEE
PPRWRVGSLAQEAPDGPESLIEVVLKADLERHALLREAETARDPERIADIQMRLVDIDAH
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEEECCC
SAPARAASILSGLGFSTADQSRPCSEFSGGWRMRVALAATLFASPDLLLLDEPTNYLDLE
CCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEHHHHHHHHHCCCCEEEEECCCCEEECC
GTLWLEDHLAHYPRTVIIISHDRDLLDTSVDQILHLDRGKLSLYKGTYSAFEEQRATREL
CEEEEHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHH
LDAKHARRQADERKRLQAFVDRFKAKASKARQAQSRVKMLERMKPVTALVTQDVREISFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPDKLLSPPIIAVDEAVVGYDPQSPILKRVTLRVDEDDRIALLGANGNGKSTLVKLLAGK
CCHHHCCCCCEEECCHHCCCCCCCCHHHHEEEEECCCCCEEEEECCCCCHHHHHHHHHHH
LQPFAGRVVRADKLSIGYFAQHQTDELDLDGSPYDHVRRLMQDAPETKIRARVGGIGFSG
CCCHHCCEEEECCCEECEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCC
KAGDTLVRSLSGGEKARLLLGLATFFAPNMIILDEPTNHLDIDSRAALAEAINEYPGAVI
CCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEE
MVSHDRYLIEACADQLWVVADHTVTPYDGDLEDYRRAVLSARGLRSNGRDRVSGQRDDGR
EEECCHHHHHHHHCCEEEEECCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DKPRRERTERRSPLKQKITAAEAEIERITGIIAKIDVALALPDLFKREPKQAAQLTKARA
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHH
SAADALRRAEEAWLEASSSYDNATG
HHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLSITDISIRIAGRLLIDHSSVQIVPGARVGFVGRNGVGKSTLFHAIRGELPTETGTIAI
CCEEEEEEEEEEEEEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEE
PPRWRVGSLAQEAPDGPESLIEVVLKADLERHALLREAETARDPERIADIQMRLVDIDAH
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEEECCC
SAPARAASILSGLGFSTADQSRPCSEFSGGWRMRVALAATLFASPDLLLLDEPTNYLDLE
CCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEHHHHHHHHHCCCCEEEEECCCCEEECC
GTLWLEDHLAHYPRTVIIISHDRDLLDTSVDQILHLDRGKLSLYKGTYSAFEEQRATREL
CEEEEHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHH
LDAKHARRQADERKRLQAFVDRFKAKASKARQAQSRVKMLERMKPVTALVTQDVREISFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPDKLLSPPIIAVDEAVVGYDPQSPILKRVTLRVDEDDRIALLGANGNGKSTLVKLLAGK
CCHHHCCCCCEEECCHHCCCCCCCCHHHHEEEEECCCCCEEEEECCCCCHHHHHHHHHHH
LQPFAGRVVRADKLSIGYFAQHQTDELDLDGSPYDHVRRLMQDAPETKIRARVGGIGFSG
CCCHHCCEEEECCCEECEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCC
KAGDTLVRSLSGGEKARLLLGLATFFAPNMIILDEPTNHLDIDSRAALAEAINEYPGAVI
CCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEE
MVSHDRYLIEACADQLWVVADHTVTPYDGDLEDYRRAVLSARGLRSNGRDRVSGQRDDGR
EEECCHHHHHHHHCCEEEEECCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DKPRRERTERRSPLKQKITAAEAEIERITGIIAKIDVALALPDLFKREPKQAAQLTKARA
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHH
SAADALRRAEEAWLEASSSYDNATG
HHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]