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The map label for this gene is degQ [H]

Identifier: 75675583

GI number: 75675583

Start: 1515861

End: 1517351

Strand: Direct

Name: degQ [H]

Synonym: Nwi_1391

Alternate gene names: 75675583

Gene position: 1515861-1517351 (Clockwise)

Preceding gene: 75675582

Following gene: 75675584

Centisome position: 44.56

GC content: 62.17

Gene sequence:

>1491_bases
ATGAGTTTGTTTTGGCGCGTTTTCTTCACGCGAGCCGGTATCCACTTCGCTCCAAAACACTATATATCTGCGATCCTGAT
CCCGGGAATCAAATTCATGACGCTGCTCCGCCTGTCCGCCGCTCTGCTCCTCTCTCTGACGATGCTGGCGCCTGCTCATG
CCCAGGACCGTCGCGTCCCGGCCTCCCAGGCCGAACTGCGGCTTTCCTATGCGCCGATCGTGCAGCGGGTGGTCCCGGCC
GTGGTCAACGTCTACGCCGCTAAAATGATTCAGCATCGCCATCCGCTGCTGGATGATCCGATATTTCGTCGTTTCTTCGG
CGTTCCGGGCGGGCAGCCGGAACAGATGCAGCGCTCGCTCGGCTCCGGCGTGATGGTCGATCCGTCCGGCCTCGTCGTGA
CGAACAATCATGTGATCGAGGGCGCGGATCAGGTCAAGATCGCGCTGCCGGACAAGCGTGAGTTCGAGGCGGAGATCGTG
CTCAAGGATACGCGCACTGATCTTGCGGTCCTGCGGTTGAAGAATGTGCATGAGAAGTTTCCGACGCTCGATTTCGCGAA
TTCGGATGAGTTGCAGGTCGGCGATGTCGTCATGGCGATCGGAAATCCGTTCGGCGTCGGGCAGACGGTGACGCAAGGCA
TCGTTTCGGCGCTGGCGCGCACGCAGGTCGGGATTACGGATTATCAATTCTTCATCCAGACCGATGCGGCGATCAATCCC
GGAAACTCGGGCGGGGCGCTGGTTGACATGACGGGCCATCTCGTCGGCATCAACACCGCGATTTTCTCGCGCACCGGCGG
GTCGCTTGGCATCGGCTTCGCCATTCCGGCCAACATGGTGCGGGTGGTGGTGGCGTCGGCCAAGAGCGGCGGCAAGGCGG
TGCGCCGGCCCTGGCTCGGAGCCCGGCTGCAGGCGGTAACCCCGGAGATTGCCGAAACCATTGGCCTCAAGGCGCCGGCC
GGTGCGCTGGTGGCCAGCGTTGCGGCTGGAAGTCCGGCGGCGCGCGCCGGTCTCAAACTGTCCGACCTGATCGTCTCGAT
CGACGGTCAGCCTGTCGATGACCCCAATGCGTTTGACTATCGGTTCGCAACGCGTCCGCTCGGCGGGACCTCGCAGCTGG
AAGTCCAGCGCAACGGAAAGCCGCTCAAGCTCACTGTTCCGCTCGAAACAGCGCCGGATACCAGTCGCGACGAGGTCGTG
ATTACCGCACCATCACCGTTCCAGGGCGCCAAGGTGGTGAATGTCTCGCCGGGGCTGGCCGATGAGCTTCATCTCGATTA
CGGCGCCGAAGGGGTCGTGATCGTCGCATTGGCGGAGAGTGGAATGGCCGCGAATGTCGGGTTCAGGAAGGGCGACATCA
TCCTCGCGGTCAACAACAAGAAGATTGTCAAGACCACCGATCTCGAACAAGCCGTTCGCGAAGCGAGGCGGCTCTGGCGG
ATCACGCTGATGCGCAGCGGCCAGCAGATTCAAGTCATGCTGGGCGGATGA

Upstream 100 bases:

>100_bases
AATCCGGAAACAGCCCGGTAATCGTCAAAAGCCAAGTCTTTCGCTTCTCCTGGAGGTTCGCGAAACCAGAGCCTCGCTTC
TGATTCAGACGCGGGACTCT

Downstream 100 bases:

>100_bases
GCCCGAAGCGCCAGCACGACTCCAGGAGCCTGTTCGCCGCGGCGGGCCTGGAGCGTGATGCGCCGCATCCGCTGCCGGAC
AGGCTGCGGCCGCAGATGCT

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSLFWRVFFTRAGIHFAPKHYISAILIPGIKFMTLLRLSAALLLSLTMLAPAHAQDRRVPASQAELRLSYAPIVQRVVPA
VVNVYAAKMIQHRHPLLDDPIFRRFFGVPGGQPEQMQRSLGSGVMVDPSGLVVTNNHVIEGADQVKIALPDKREFEAEIV
LKDTRTDLAVLRLKNVHEKFPTLDFANSDELQVGDVVMAIGNPFGVGQTVTQGIVSALARTQVGITDYQFFIQTDAAINP
GNSGGALVDMTGHLVGINTAIFSRTGGSLGIGFAIPANMVRVVVASAKSGGKAVRRPWLGARLQAVTPEIAETIGLKAPA
GALVASVAAGSPAARAGLKLSDLIVSIDGQPVDDPNAFDYRFATRPLGGTSQLEVQRNGKPLKLTVPLETAPDTSRDEVV
ITAPSPFQGAKVVNVSPGLADELHLDYGAEGVVIVALAESGMAANVGFRKGDIILAVNNKKIVKTTDLEQAVREARRLWR
ITLMRSGQQIQVMLGG

Sequences:

>Translated_496_residues
MSLFWRVFFTRAGIHFAPKHYISAILIPGIKFMTLLRLSAALLLSLTMLAPAHAQDRRVPASQAELRLSYAPIVQRVVPA
VVNVYAAKMIQHRHPLLDDPIFRRFFGVPGGQPEQMQRSLGSGVMVDPSGLVVTNNHVIEGADQVKIALPDKREFEAEIV
LKDTRTDLAVLRLKNVHEKFPTLDFANSDELQVGDVVMAIGNPFGVGQTVTQGIVSALARTQVGITDYQFFIQTDAAINP
GNSGGALVDMTGHLVGINTAIFSRTGGSLGIGFAIPANMVRVVVASAKSGGKAVRRPWLGARLQAVTPEIAETIGLKAPA
GALVASVAAGSPAARAGLKLSDLIVSIDGQPVDDPNAFDYRFATRPLGGTSQLEVQRNGKPLKLTVPLETAPDTSRDEVV
ITAPSPFQGAKVVNVSPGLADELHLDYGAEGVVIVALAESGMAANVGFRKGDIILAVNNKKIVKTTDLEQAVREARRLWR
ITLMRSGQQIQVMLGG
>Mature_495_residues
SLFWRVFFTRAGIHFAPKHYISAILIPGIKFMTLLRLSAALLLSLTMLAPAHAQDRRVPASQAELRLSYAPIVQRVVPAV
VNVYAAKMIQHRHPLLDDPIFRRFFGVPGGQPEQMQRSLGSGVMVDPSGLVVTNNHVIEGADQVKIALPDKREFEAEIVL
KDTRTDLAVLRLKNVHEKFPTLDFANSDELQVGDVVMAIGNPFGVGQTVTQGIVSALARTQVGITDYQFFIQTDAAINPG
NSGGALVDMTGHLVGINTAIFSRTGGSLGIGFAIPANMVRVVVASAKSGGKAVRRPWLGARLQAVTPEIAETIGLKAPAG
ALVASVAAGSPAARAGLKLSDLIVSIDGQPVDDPNAFDYRFATRPLGGTSQLEVQRNGKPLKLTVPLETAPDTSRDEVVI
TAPSPFQGAKVVNVSPGLADELHLDYGAEGVVIVALAESGMAANVGFRKGDIILAVNNKKIVKTTDLEQAVREARRLWRI
TLMRSGQQIQVMLGG

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=336, Percent_Identity=32.4404761904762, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI4506141, Length=345, Percent_Identity=32.1739130434783, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI24308541, Length=307, Percent_Identity=31.2703583061889, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI7019477, Length=325, Percent_Identity=34.4615384615385, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1789629, Length=470, Percent_Identity=37.4468085106383, Blast_Score=268, Evalue=8e-73,
Organism=Escherichia coli, GI1786356, Length=458, Percent_Identity=34.9344978165939, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI1789630, Length=338, Percent_Identity=38.7573964497041, Blast_Score=197, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24646839, Length=307, Percent_Identity=30.9446254071661, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 52982; Mature: 52851

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFWRVFFTRAGIHFAPKHYISAILIPGIKFMTLLRLSAALLLSLTMLAPAHAQDRRVP
CCCEEEEHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ASQAELRLSYAPIVQRVVPAVVNVYAAKMIQHRHPLLDDPIFRRFFGVPGGQPEQMQRSL
CCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHH
GSGVMVDPSGLVVTNNHVIEGADQVKIALPDKREFEAEIVLKDTRTDLAVLRLKNVHEKF
CCCEEECCCCEEEECCEEECCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHC
PTLDFANSDELQVGDVVMAIGNPFGVGQTVTQGIVSALARTQVGITDYQFFIQTDAAINP
CCCCCCCCCCCEECCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCEECC
GNSGGALVDMTGHLVGINTAIFSRTGGSLGIGFAIPANMVRVVVASAKSGGKAVRRPWLG
CCCCCEEEEECCEEEEEEHEEEECCCCCEEEEEECHHHHHEEHEECCCCCCHHHHCCCCC
ARLQAVTPEIAETIGLKAPAGALVASVAAGSPAARAGLKLSDLIVSIDGQPVDDPNAFDY
CCHHHCCHHHHHHHCCCCCCHHHHHHHHCCCCHHHCCCEEEEEEEEECCCCCCCCCCCEE
RFATRPLGGTSQLEVQRNGKPLKLTVPLETAPDTSRDEVVITAPSPFQGAKVVNVSPGLA
EEECCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCEEEEECCCCC
DELHLDYGAEGVVIVALAESGMAANVGFRKGDIILAVNNKKIVKTTDLEQAVREARRLWR
CCEEECCCCCCEEEEEEECCCCEEECCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHH
ITLMRSGQQIQVMLGG
HHEECCCCEEEEEECC
>Mature Secondary Structure 
SLFWRVFFTRAGIHFAPKHYISAILIPGIKFMTLLRLSAALLLSLTMLAPAHAQDRRVP
CCEEEEHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ASQAELRLSYAPIVQRVVPAVVNVYAAKMIQHRHPLLDDPIFRRFFGVPGGQPEQMQRSL
CCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHH
GSGVMVDPSGLVVTNNHVIEGADQVKIALPDKREFEAEIVLKDTRTDLAVLRLKNVHEKF
CCCEEECCCCEEEECCEEECCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHC
PTLDFANSDELQVGDVVMAIGNPFGVGQTVTQGIVSALARTQVGITDYQFFIQTDAAINP
CCCCCCCCCCCEECCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCEECC
GNSGGALVDMTGHLVGINTAIFSRTGGSLGIGFAIPANMVRVVVASAKSGGKAVRRPWLG
CCCCCEEEEECCEEEEEEHEEEECCCCCEEEEEECHHHHHEEHEECCCCCCHHHHCCCCC
ARLQAVTPEIAETIGLKAPAGALVASVAAGSPAARAGLKLSDLIVSIDGQPVDDPNAFDY
CCHHHCCHHHHHHHCCCCCCHHHHHHHHCCCCHHHCCCEEEEEEEEECCCCCCCCCCCEE
RFATRPLGGTSQLEVQRNGKPLKLTVPLETAPDTSRDEVVITAPSPFQGAKVVNVSPGLA
EEECCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCEEEEECCCCC
DELHLDYGAEGVVIVALAESGMAANVGFRKGDIILAVNNKKIVKTTDLEQAVREARRLWR
CCEEECCCCCCEEEEEEECCCCEEECCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHH
ITLMRSGQQIQVMLGG
HHEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]