Click here to switch to the map view.

The map label for this gene is ybdL [H]

Identifier: 75675433

GI number: 75675433

Start: 1364577

End: 1365728

Strand: Direct

Name: ybdL [H]

Synonym: Nwi_1240

Alternate gene names: 75675433

Gene position: 1364577-1365728 (Clockwise)

Preceding gene: 75675432

Following gene: 75675434

Centisome position: 40.11

GC content: 63.19

Gene sequence:

>1152_bases
ATGAACAAGGTCTTCGCTGACCTGCCGGTGACCATCTTCGAGACCATGTCGCAGCTCGCGCGCGACCACGACGCCATCAA
CCTCGGGCAGGGTTTTCCCGACGATCCGGGCCCGGAGGATATCCGGCGCGCGGCGGCGGACGCCGTTATCAACGGTTACA
ATCAGTACCCATCGATGATGGGCATTCCGGAGTTGCGGCAGGCGGTCGCCGCTCACTACCGCCACTGGCACGGTCTTGCG
GCCGATCCGGCGAGTGAGGTGATGGTTACCTCCGGCGGGACGGAAGCGCTGACCAGCGCCATTCTCGCGACGGTAGAACC
GGGCGACGAGGTCGTCGTCTTCCAGCCGTTCTACGACTCCTACCTTCCGATCATACGGCAGGCCGGCGGCGTTCCGCGTC
TGGTTCGGCTGGAGCCGCCGCACTGGCGGTTGACGGAAGACGCGCTGCGCGACGCCTTCACCCCCAGGACCAGGGTCGTA
CTTTTCAACAATCCGCTGAATCCGGCTGCGGTGGTCTATGCGCGCAATGAACTGGAATTGCTGGCGCGGTTTTGCCAGGA
GTTCGATGCGGTCGCGATCTGCGACGAGGTCTGGGAGCATGTGGTTTTCGACGGCCGCGAGCATATTCCGCTGATCACCG
TTCCCGGCATGCGCGACCGCACCATCAAGATCGGATCGGCCGGAAAGATATTCTCCCTGACGGGCTGGAAGGTCGGCTTT
GTCTGCGCCGCGCCGCCGCTTTTGCGGGTCATCGCCAAGGTGCATCAGTTTCTCACCTTCACCACACCTCCCAATCTTCA
GGCCGCGGTCGCCGGGGGCCTTGCGAAGCCGGACGATTATTTTTTCGAGATGCGCCGCGATCTGGCGCGCCGCCGCGACC
GCCTGACCCGCGGCCTCGAAGACATCGGGTTTCCGGTGCTGCCGTCGCAAGGAACCTATTTCCTGACCGTCGATCTCGCG
CCGCTCGGACTCAATGAAACCGATCATGTGTTCTGCAGGCGCATCGTCGTGGACCATAAGGTCGCGGCGATCCCGGTTTC
AGCGTTCTACGAAAAGGACGCGGTTACCTCGGTCGTACGTTTCTGTTTCGCGAAGAAGGATGCCACGCTCGACGCTGCGC
TGGAGCGGCTATCCGACGCCGTGCGGAGGTGA

Upstream 100 bases:

>100_bases
CGCCGGCCTTCCTTACGACAAGCATCTCGACGGCGGAATTCTGGGATGGAAGGCGGCAGGGTTGCCGACACGATCCGGCG
GCTGAGAGTTGACGCTCTCG

Downstream 100 bases:

>100_bases
GGCCGATGATTCCGAACCAATGCGTGTGGTTCTGGGCGCCCGTTGCATTGATGCTTGGTTCGGGCGCGGTCTTGTCGCCG
CGCGCCGACGCCGCCGAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MNKVFADLPVTIFETMSQLARDHDAINLGQGFPDDPGPEDIRRAAADAVINGYNQYPSMMGIPELRQAVAAHYRHWHGLA
ADPASEVMVTSGGTEALTSAILATVEPGDEVVVFQPFYDSYLPIIRQAGGVPRLVRLEPPHWRLTEDALRDAFTPRTRVV
LFNNPLNPAAVVYARNELELLARFCQEFDAVAICDEVWEHVVFDGREHIPLITVPGMRDRTIKIGSAGKIFSLTGWKVGF
VCAAPPLLRVIAKVHQFLTFTTPPNLQAAVAGGLAKPDDYFFEMRRDLARRRDRLTRGLEDIGFPVLPSQGTYFLTVDLA
PLGLNETDHVFCRRIVVDHKVAAIPVSAFYEKDAVTSVVRFCFAKKDATLDAALERLSDAVRR

Sequences:

>Translated_383_residues
MNKVFADLPVTIFETMSQLARDHDAINLGQGFPDDPGPEDIRRAAADAVINGYNQYPSMMGIPELRQAVAAHYRHWHGLA
ADPASEVMVTSGGTEALTSAILATVEPGDEVVVFQPFYDSYLPIIRQAGGVPRLVRLEPPHWRLTEDALRDAFTPRTRVV
LFNNPLNPAAVVYARNELELLARFCQEFDAVAICDEVWEHVVFDGREHIPLITVPGMRDRTIKIGSAGKIFSLTGWKVGF
VCAAPPLLRVIAKVHQFLTFTTPPNLQAAVAGGLAKPDDYFFEMRRDLARRRDRLTRGLEDIGFPVLPSQGTYFLTVDLA
PLGLNETDHVFCRRIVVDHKVAAIPVSAFYEKDAVTSVVRFCFAKKDATLDAALERLSDAVRR
>Mature_383_residues
MNKVFADLPVTIFETMSQLARDHDAINLGQGFPDDPGPEDIRRAAADAVINGYNQYPSMMGIPELRQAVAAHYRHWHGLA
ADPASEVMVTSGGTEALTSAILATVEPGDEVVVFQPFYDSYLPIIRQAGGVPRLVRLEPPHWRLTEDALRDAFTPRTRVV
LFNNPLNPAAVVYARNELELLARFCQEFDAVAICDEVWEHVVFDGREHIPLITVPGMRDRTIKIGSAGKIFSLTGWKVGF
VCAAPPLLRVIAKVHQFLTFTTPPNLQAAVAGGLAKPDDYFFEMRRDLARRRDRLTRGLEDIGFPVLPSQGTYFLTVDLA
PLGLNETDHVFCRRIVVDHKVAAIPVSAFYEKDAVTSVVRFCFAKKDATLDAALERLSDAVRR

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=394, Percent_Identity=38.8324873096447, Blast_Score=269, Evalue=4e-72,
Organism=Homo sapiens, GI169881279, Length=394, Percent_Identity=38.8324873096447, Blast_Score=269, Evalue=4e-72,
Organism=Homo sapiens, GI56713254, Length=398, Percent_Identity=36.1809045226131, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=36.0201511335013, Blast_Score=252, Evalue=5e-67,
Organism=Homo sapiens, GI169881281, Length=394, Percent_Identity=33.756345177665, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI4507369, Length=332, Percent_Identity=22.8915662650602, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786816, Length=371, Percent_Identity=39.622641509434, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1788722, Length=387, Percent_Identity=25.3229974160207, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788627, Length=193, Percent_Identity=23.8341968911917, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=406, Percent_Identity=34.9753694581281, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71994472, Length=406, Percent_Identity=34.9753694581281, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=29.3969849246231, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI17567663, Length=307, Percent_Identity=22.1498371335505, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=32.2164948453608, Blast_Score=188, Evalue=1e-48,
Organism=Drosophila melanogaster, GI28573069, Length=400, Percent_Identity=36.75, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24646114, Length=400, Percent_Identity=36.75, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI28573067, Length=400, Percent_Identity=36.75, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI28573065, Length=400, Percent_Identity=36.75, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI18859735, Length=345, Percent_Identity=26.0869565217391, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42521; Mature: 42521

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVFADLPVTIFETMSQLARDHDAINLGQGFPDDPGPEDIRRAAADAVINGYNQYPSMM
CCCEECCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCHHHCCCCC
GIPELRQAVAAHYRHWHGLAADPASEVMVTSGGTEALTSAILATVEPGDEVVVFQPFYDS
CCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHEECCCCCEEEECCCHHH
YLPIIRQAGGVPRLVRLEPPHWRLTEDALRDAFTPRTRVVLFNNPLNPAAVVYARNELEL
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCCCCEEEEEEECCCCCEEEEEECHHHHH
LARFCQEFDAVAICDEVWEHVVFDGREHIPLITVPGMRDRTIKIGSAGKIFSLTGWKVGF
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEECCCCCEEEECCCEEEE
VCAAPPLLRVIAKVHQFLTFTTPPNLQAAVAGGLAKPDDYFFEMRRDLARRRDRLTRGLE
EECCCHHHHHHHHHHHHEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DIGFPVLPSQGTYFLTVDLAPLGLNETDHVFCRRIVVDHKVAAIPVSAFYEKDAVTSVVR
HCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHH
FCFAKKDATLDAALERLSDAVRR
HHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKVFADLPVTIFETMSQLARDHDAINLGQGFPDDPGPEDIRRAAADAVINGYNQYPSMM
CCCEECCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCHHHCCCCC
GIPELRQAVAAHYRHWHGLAADPASEVMVTSGGTEALTSAILATVEPGDEVVVFQPFYDS
CCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHEECCCCCEEEECCCHHH
YLPIIRQAGGVPRLVRLEPPHWRLTEDALRDAFTPRTRVVLFNNPLNPAAVVYARNELEL
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCCCCEEEEEEECCCCCEEEEEECHHHHH
LARFCQEFDAVAICDEVWEHVVFDGREHIPLITVPGMRDRTIKIGSAGKIFSLTGWKVGF
HHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEECCCCCEEEECCCEEEE
VCAAPPLLRVIAKVHQFLTFTTPPNLQAAVAGGLAKPDDYFFEMRRDLARRRDRLTRGLE
EECCCHHHHHHHHHHHHEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DIGFPVLPSQGTYFLTVDLAPLGLNETDHVFCRRIVVDHKVAAIPVSAFYEKDAVTSVVR
HCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHH
FCFAKKDATLDAALERLSDAVRR
HHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]