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The map label for this gene is cutL [H]

Identifier: 75675272

GI number: 75675272

Start: 1182912

End: 1185203

Strand: Direct

Name: cutL [H]

Synonym: Nwi_1079

Alternate gene names: 75675272

Gene position: 1182912-1185203 (Clockwise)

Preceding gene: 75675271

Following gene: 75675275

Centisome position: 34.77

GC content: 64.57

Gene sequence:

>2292_bases
ATGGCTCCCGTCAAGTTCGGCATAGGCCAGAGCGTCCGGCGCAAGGAAGACGACGCCTTCATTCGCGGCAAGGGGCGCTA
TACCGACGATCACGCGCCGCCCGATGCGCTACATGCGCTGATGCTGCGCTCACCCCATGCTCATGCGGCGTACAGGATCG
ATGTGTCGCGCGCCTGTCGCTTGCCGGGGGTTGCCCTGATCCTCACCGCGACAGATGTCGCCGATCTCGGGGGCCTGCCC
TGTCAGGTCGAGTTGCCGGACCAGCCTTTCATTGCGCCGCCATATCCTATCCTGCCGAAGGATGAAGTGCGGCATGTCGG
GGACGCCATCGCTTTTGTGGTGGCCGATACGGTCGAGCGCGCGCGCGACGCGCTGGAGGCGATCGAGGTCGAGTGGACGC
CGCTGGCCTCCGTCGTCGGCGTTGCCGATGCCGTGAGGGATGGCGCGCCTCAGGTGTGGCCCGATCACGCCGGCAACGTT
TTGTTCGACGTTTCGCTCGGCGACAGGAAGGCGGCCGATGCCGCTTTCGCCGCGGCGGATGCCGTGGCCGAGATTTCGAT
CGTCAACCCGCGCGTCGTCACCAACTATATGGAGACGCGCGCCGCGGTCTGCGTGTACGACGCGAGGCGAGACCATCTGA
CCTTGACGGTCGGCAGCCAGGGCAGCCATCGCCTGCGTGAGATTCTCTGCGAGAACGTGCTGGGGATACCGCTGGAAAAG
ATGCGCGTGATCTGTCCCGATGTCGGCGGCGGATTCGGCACCAAGCTGTTTCCCTATCGCGAATATGCGCTGATCGCGGT
CGCCGCGAAGAAACTTCACACGGCGATCAGATGGACGGCGGAGAGGTCGGACCATTTCGTCGGCGACTCGCAGGGGCGCG
ACAACGTCACCACCGCGCGCATGGCGCTGGCCGGCGACGGCAGGTTCCTCGGCATGGATGTCGATCTGATGGGAGATATG
GGCGCCTATCTATCGACCTTCGGTCCCGACATTCCCTATAGCGGGGCCGGGATGCTACCGGGCCTCTACGATATCCAGGC
ATTTCATTGCCGTGTCCGCGCGGTGTTCACCAACACCGTGCCGGTCGATGCCTATCGCGGCGCAGGCCGGCCCGAGGCGG
CCTATGTCGTGGAGCGGCTGGTCGATGCCGCGGCACGCAAGATCGGCATGACGCCGGATGCGATCCGGCGCAAAAACTTC
ATTCCGCCGGAGGCGATGCCGTACAGGACCGCGACGGGCAAGATCTATGACTCCGGCGATTTCGCGGCCCACATGGCGCG
CGCGATGGAGATCGCGAAATGGCGGGAGTTTGCCGGCCGGGCCGAGGCTGCAAAAGAGCGGGGCCTTGTTCGTGGCATCG
GTTTGGCCACCTATGTCGAGGTCTGCGGCACCATGGGGCGCGAGCGGGCGGATGTGCGGCTTGACGCCAACGGCGACGTT
ACGGTGCTGATCGGCACGCAATCAACCGGGCAGGGCCATGCCACCGCCTATGCGCAGATTATCGCCGATCAGTTCGGGAT
ACCTCCCGAGCGGGTTCACATGAAGCAGGGCGATACCGATGTGGTCACCACCGGACTCGGTACCGGCGGATCGAGTTCGA
TTCCCTCCGGCGGCGTCAGCGTCGAGCGGGCAACCCGCAAGCTCGGCGTCAGACTTCGGGAGATCGCGTCCGAGGCGCTC
GAAACCAGCGCCGCCGACCTTGAGATCAGCGACGGTTCGATCCGTATCGCCGGCACGGACCGCTTCGTTTCCTTCGCCGA
CCTCGCGAAGCGCGCTGATCTGTCGAAGCTGACCGCCGACGAGAGTTTCAGCAGCGCCGACGGCACTTATCCCAACGGCA
CCCATGTCGTGGAAGTCGAGATCGATCCGGCGACTGGAAAGATCGAGTTGGTGAATTACGTGGTGGTCGACGATTTCGGC
GTGACGTTGAATCCATTGCTTCTGGCGGGGCAGGTCCATGGCGGCGCCATGCAGGGCATCGGCCAGGCGCTTATGGAGCA
GACGGTCTATGATGCGGATGGGCAGCTTGTCACCGGAACGTTGATGGATTATGCGGTGCCGCGCGCGGCCGACGGGGTCT
CGATCACATTCGAGACCCGCAACGTTCCCTGCGCCACCAATCCTCTCGGGATCAAGGGAGCAGGCGAGGCGGGCGCCATC
GGTTCCTGCCCGGCGGTGGTCAATGCCATCATCGATGGTTTGTGGCGGGAGTACGGAATCGACCACATCGACATGCCTGC
GACTCCGGAACGGGTCTGGACGGCGATCCGGGACGCTCAGCGACGCTTGTGA

Upstream 100 bases:

>100_bases
GCGCGAACATTGCGCTCGGTGCTGTTCCGCTGCACTATTGCGGTGATCCGGGACGATAGCTTGGAGTTCCCATGGCTTTC
ATAAAACGGCTCCCGTAAAA

Downstream 100 bases:

>100_bases
AGTAATAGGGCCGGAAAGCCTACTTCGTGACCTGCCCGCGGATTTCGCCGCCGGGATGGTCCGCGGTATGGACGTTGACA
TAATACCTGCCGGCCAGCAG

Product: aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 763; Mature: 762

Protein sequence:

>763_residues
MAPVKFGIGQSVRRKEDDAFIRGKGRYTDDHAPPDALHALMLRSPHAHAAYRIDVSRACRLPGVALILTATDVADLGGLP
CQVELPDQPFIAPPYPILPKDEVRHVGDAIAFVVADTVERARDALEAIEVEWTPLASVVGVADAVRDGAPQVWPDHAGNV
LFDVSLGDRKAADAAFAAADAVAEISIVNPRVVTNYMETRAAVCVYDARRDHLTLTVGSQGSHRLREILCENVLGIPLEK
MRVICPDVGGGFGTKLFPYREYALIAVAAKKLHTAIRWTAERSDHFVGDSQGRDNVTTARMALAGDGRFLGMDVDLMGDM
GAYLSTFGPDIPYSGAGMLPGLYDIQAFHCRVRAVFTNTVPVDAYRGAGRPEAAYVVERLVDAAARKIGMTPDAIRRKNF
IPPEAMPYRTATGKIYDSGDFAAHMARAMEIAKWREFAGRAEAAKERGLVRGIGLATYVEVCGTMGRERADVRLDANGDV
TVLIGTQSTGQGHATAYAQIIADQFGIPPERVHMKQGDTDVVTTGLGTGGSSSIPSGGVSVERATRKLGVRLREIASEAL
ETSAADLEISDGSIRIAGTDRFVSFADLAKRADLSKLTADESFSSADGTYPNGTHVVEVEIDPATGKIELVNYVVVDDFG
VTLNPLLLAGQVHGGAMQGIGQALMEQTVYDADGQLVTGTLMDYAVPRAADGVSITFETRNVPCATNPLGIKGAGEAGAI
GSCPAVVNAIIDGLWREYGIDHIDMPATPERVWTAIRDAQRRL

Sequences:

>Translated_763_residues
MAPVKFGIGQSVRRKEDDAFIRGKGRYTDDHAPPDALHALMLRSPHAHAAYRIDVSRACRLPGVALILTATDVADLGGLP
CQVELPDQPFIAPPYPILPKDEVRHVGDAIAFVVADTVERARDALEAIEVEWTPLASVVGVADAVRDGAPQVWPDHAGNV
LFDVSLGDRKAADAAFAAADAVAEISIVNPRVVTNYMETRAAVCVYDARRDHLTLTVGSQGSHRLREILCENVLGIPLEK
MRVICPDVGGGFGTKLFPYREYALIAVAAKKLHTAIRWTAERSDHFVGDSQGRDNVTTARMALAGDGRFLGMDVDLMGDM
GAYLSTFGPDIPYSGAGMLPGLYDIQAFHCRVRAVFTNTVPVDAYRGAGRPEAAYVVERLVDAAARKIGMTPDAIRRKNF
IPPEAMPYRTATGKIYDSGDFAAHMARAMEIAKWREFAGRAEAAKERGLVRGIGLATYVEVCGTMGRERADVRLDANGDV
TVLIGTQSTGQGHATAYAQIIADQFGIPPERVHMKQGDTDVVTTGLGTGGSSSIPSGGVSVERATRKLGVRLREIASEAL
ETSAADLEISDGSIRIAGTDRFVSFADLAKRADLSKLTADESFSSADGTYPNGTHVVEVEIDPATGKIELVNYVVVDDFG
VTLNPLLLAGQVHGGAMQGIGQALMEQTVYDADGQLVTGTLMDYAVPRAADGVSITFETRNVPCATNPLGIKGAGEAGAI
GSCPAVVNAIIDGLWREYGIDHIDMPATPERVWTAIRDAQRRL
>Mature_762_residues
APVKFGIGQSVRRKEDDAFIRGKGRYTDDHAPPDALHALMLRSPHAHAAYRIDVSRACRLPGVALILTATDVADLGGLPC
QVELPDQPFIAPPYPILPKDEVRHVGDAIAFVVADTVERARDALEAIEVEWTPLASVVGVADAVRDGAPQVWPDHAGNVL
FDVSLGDRKAADAAFAAADAVAEISIVNPRVVTNYMETRAAVCVYDARRDHLTLTVGSQGSHRLREILCENVLGIPLEKM
RVICPDVGGGFGTKLFPYREYALIAVAAKKLHTAIRWTAERSDHFVGDSQGRDNVTTARMALAGDGRFLGMDVDLMGDMG
AYLSTFGPDIPYSGAGMLPGLYDIQAFHCRVRAVFTNTVPVDAYRGAGRPEAAYVVERLVDAAARKIGMTPDAIRRKNFI
PPEAMPYRTATGKIYDSGDFAAHMARAMEIAKWREFAGRAEAAKERGLVRGIGLATYVEVCGTMGRERADVRLDANGDVT
VLIGTQSTGQGHATAYAQIIADQFGIPPERVHMKQGDTDVVTTGLGTGGSSSIPSGGVSVERATRKLGVRLREIASEALE
TSAADLEISDGSIRIAGTDRFVSFADLAKRADLSKLTADESFSSADGTYPNGTHVVEVEIDPATGKIELVNYVVVDDFGV
TLNPLLLAGQVHGGAMQGIGQALMEQTVYDADGQLVTGTLMDYAVPRAADGVSITFETRNVPCATNPLGIKGAGEAGAIG
SCPAVVNAIIDGLWREYGIDHIDMPATPERVWTAIRDAQRRL

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=779, Percent_Identity=24.6469833119384, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI91823271, Length=775, Percent_Identity=23.741935483871, Blast_Score=139, Evalue=1e-32,
Organism=Escherichia coli, GI1789246, Length=805, Percent_Identity=26.2111801242236, Blast_Score=221, Evalue=2e-58,
Organism=Escherichia coli, GI1789230, Length=766, Percent_Identity=28.4595300261097, Blast_Score=216, Evalue=6e-57,
Organism=Escherichia coli, GI1786478, Length=730, Percent_Identity=26.8493150684932, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17540638, Length=790, Percent_Identity=25.1898734177215, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17539860, Length=773, Percent_Identity=23.9327296248383, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32566215, Length=587, Percent_Identity=25.5536626916525, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17737937, Length=719, Percent_Identity=24.6175243393602, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24647193, Length=714, Percent_Identity=23.3893557422969, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647199, Length=703, Percent_Identity=21.9061166429587, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24647201, Length=686, Percent_Identity=22.1574344023324, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24647195, Length=556, Percent_Identity=23.9208633093525, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647197, Length=330, Percent_Identity=28.4848484848485, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 81556; Mature: 81425

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPVKFGIGQSVRRKEDDAFIRGKGRYTDDHAPPDALHALMLRSPHAHAAYRIDVSRACR
CCCCCCCCCCHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEHHHHCC
LPGVALILTATDVADLGGLPCQVELPDQPFIAPPYPILPKDEVRHVGDAIAFVVADTVER
CCCEEEEEEECCHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARDALEAIEVEWTPLASVVGVADAVRDGAPQVWPDHAGNVLFDVSLGDRKAADAAFAAAD
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
AVAEISIVNPRVVTNYMETRAAVCVYDARRDHLTLTVGSQGSHRLREILCENVLGIPLEK
HHHEEEECCCHHHHHHHHHCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHH
MRVICPDVGGGFGTKLFPYREYALIAVAAKKLHTAIRWTAERSDHFVGDSQGRDNVTTAR
HEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCEEEE
MALAGDGRFLGMDVDLMGDMGAYLSTFGPDIPYSGAGMLPGLYDIQAFHCRVRAVFTNTV
EEEECCCEEEEEEHHHHCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHEEEEEEEEECCC
PVDAYRGAGRPEAAYVVERLVDAAARKIGMTPDAIRRKNFIPPEAMPYRTATGKIYDSGD
CCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCEEEECCH
FAAHMARAMEIAKWREFAGRAEAAKERGLVRGIGLATYVEVCGTMGRERADVRLDANGDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCE
TVLIGTQSTGQGHATAYAQIIADQFGIPPERVHMKQGDTDVVTTGLGTGGSSSIPSGGVS
EEEEECCCCCCCHHHHHHHHHHHHHCCCHHHEEECCCCCCEEEECCCCCCCCCCCCCCCH
VERATRKLGVRLREIASEALETSAADLEISDGSIRIAGTDRFVSFADLAKRADLSKLTAD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCHHHHHHHHHHHCCHHHHHCC
ESFSSADGTYPNGTHVVEVEIDPATGKIELVNYVVVDDFGVTLNPLLLAGQVHGGAMQGI
CCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCHHHHHH
GQALMEQTVYDADGQLVTGTLMDYAVPRAADGVSITFETRNVPCATNPLGIKGAGEAGAI
HHHHHHHHHCCCCCCEEEHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
GSCPAVVNAIIDGLWREYGIDHIDMPATPERVWTAIRDAQRRL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
APVKFGIGQSVRRKEDDAFIRGKGRYTDDHAPPDALHALMLRSPHAHAAYRIDVSRACR
CCCCCCCCCHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEHHHHCC
LPGVALILTATDVADLGGLPCQVELPDQPFIAPPYPILPKDEVRHVGDAIAFVVADTVER
CCCEEEEEEECCHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARDALEAIEVEWTPLASVVGVADAVRDGAPQVWPDHAGNVLFDVSLGDRKAADAAFAAAD
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
AVAEISIVNPRVVTNYMETRAAVCVYDARRDHLTLTVGSQGSHRLREILCENVLGIPLEK
HHHEEEECCCHHHHHHHHHCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHH
MRVICPDVGGGFGTKLFPYREYALIAVAAKKLHTAIRWTAERSDHFVGDSQGRDNVTTAR
HEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCEEEE
MALAGDGRFLGMDVDLMGDMGAYLSTFGPDIPYSGAGMLPGLYDIQAFHCRVRAVFTNTV
EEEECCCEEEEEEHHHHCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHEEEEEEEEECCC
PVDAYRGAGRPEAAYVVERLVDAAARKIGMTPDAIRRKNFIPPEAMPYRTATGKIYDSGD
CCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCEEEECCH
FAAHMARAMEIAKWREFAGRAEAAKERGLVRGIGLATYVEVCGTMGRERADVRLDANGDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCE
TVLIGTQSTGQGHATAYAQIIADQFGIPPERVHMKQGDTDVVTTGLGTGGSSSIPSGGVS
EEEEECCCCCCCHHHHHHHHHHHHHCCCHHHEEECCCCCCEEEECCCCCCCCCCCCCCCH
VERATRKLGVRLREIASEALETSAADLEISDGSIRIAGTDRFVSFADLAKRADLSKLTAD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCHHHHHHHHHHHCCHHHHHCC
ESFSSADGTYPNGTHVVEVEIDPATGKIELVNYVVVDDFGVTLNPLLLAGQVHGGAMQGI
CCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCHHHHHH
GQALMEQTVYDADGQLVTGTLMDYAVPRAADGVSITFETRNVPCATNPLGIKGAGEAGAI
HHHHHHHHHCCCCCCEEEHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
GSCPAVVNAIIDGLWREYGIDHIDMPATPERVWTAIRDAQRRL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]