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The map label for this gene is mtgA

Identifier: 75674694

GI number: 75674694

Start: 553729

End: 554409

Strand: Direct

Name: mtgA

Synonym: Nwi_0496

Alternate gene names: 75674694

Gene position: 553729-554409 (Clockwise)

Preceding gene: 75674692

Following gene: 75674695

Centisome position: 16.28

GC content: 65.79

Gene sequence:

>681_bases
ATGCGACGGGCGATCCGCGTCATGGCGCTCTCCGCCATCGGCCTGTTGTTGTTGCCTTATCTGCTGACGCCGCTGTATCG
GATCGGCCATCCGGTCTCGACGCTGATGATATGGCGCACGCTTTCGGGCGCGCCGATGTCGCGGCAGTGGATCGATTTCG
CCGCGCTTCCGCCGTCGCTTCCGCGTTCCGTGGTCGCGTCGGAGGACGCCAAGTTCTGTAGCCATCAGGGCATCGATTGG
GATTCGCTGCGGGAAGTGCTCGACGATGCCGAGGACGGCGAGTTCAAGCGCGGCGGCTCCACCATCACGCAGCAGGTGGC
GAAGAATCTGTTTCTCTGGCCGGGACGCAGCATGGTCCGCAAGGCGCTGGAATTTCCGCTGGCGATGTGGATCGATGCGG
TGCTGTCCAAGCAGCGGATTCTCGAAATCTATCTGAACATCGCGGAATGGGGCCCGGGCGGCCAGTTCGGTGTCGAGGCA
GGGTCGCGCTATGCTTTCGGGCGATCCGCGGCCAGCCTGACGGCCCGTGAGGCGGCGCTAATGGCGGCGATCCTGCCCAA
TCCGGTCCGGCGCAGCGCCCGAAAGCCGGGTCCGGGAGTCCGCCGGCTGGCCGGGACCTATATGGCCCGGGCCCGGGCGG
CTGAACTGCGCGGTTGCTGGAGCGGCAATCGTAGCCTATAA

Upstream 100 bases:

>100_bases
CTGCCGCCGGCTCCGGTGTCATCAAGGGTGATTTCGTGAAGGCTCCTCGTCGCGGACACGGTGAAGCTGCCCGCCGATCG
ATTAAAGGCTTCGGGGCCTG

Downstream 100 bases:

>100_bases
GGCCGGGCTTACCAGCATTCAGCTCGCGCGTCCGCCATTTGTCGCGCCTGCCCGCCGACGTTCCGAGACGGAACTCGACA
ACATCCTGCAAGGACACCGG

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MRRAIRVMALSAIGLLLLPYLLTPLYRIGHPVSTLMIWRTLSGAPMSRQWIDFAALPPSLPRSVVASEDAKFCSHQGIDW
DSLREVLDDAEDGEFKRGGSTITQQVAKNLFLWPGRSMVRKALEFPLAMWIDAVLSKQRILEIYLNIAEWGPGGQFGVEA
GSRYAFGRSAASLTAREAALMAAILPNPVRRSARKPGPGVRRLAGTYMARARAAELRGCWSGNRSL

Sequences:

>Translated_226_residues
MRRAIRVMALSAIGLLLLPYLLTPLYRIGHPVSTLMIWRTLSGAPMSRQWIDFAALPPSLPRSVVASEDAKFCSHQGIDW
DSLREVLDDAEDGEFKRGGSTITQQVAKNLFLWPGRSMVRKALEFPLAMWIDAVLSKQRILEIYLNIAEWGPGGQFGVEA
GSRYAFGRSAASLTAREAALMAAILPNPVRRSARKPGPGVRRLAGTYMARARAAELRGCWSGNRSL
>Mature_226_residues
MRRAIRVMALSAIGLLLLPYLLTPLYRIGHPVSTLMIWRTLSGAPMSRQWIDFAALPPSLPRSVVASEDAKFCSHQGIDW
DSLREVLDDAEDGEFKRGGSTITQQVAKNLFLWPGRSMVRKALEFPLAMWIDAVLSKQRILEIYLNIAEWGPGGQFGVEA
GSRYAFGRSAASLTAREAALMAAILPNPVRRSARKPGPGVRRLAGTYMARARAAELRGCWSGNRSL

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=179, Percent_Identity=45.2513966480447, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082258, Length=139, Percent_Identity=35.9712230215827, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1786343, Length=152, Percent_Identity=36.8421052631579, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_NITWN (Q3SVC8)

Other databases:

- EMBL:   CP000115
- RefSeq:   YP_317115.1
- ProteinModelPortal:   Q3SVC8
- SMR:   Q3SVC8
- STRING:   Q3SVC8
- GeneID:   3675497
- GenomeReviews:   CP000115_GR
- KEGG:   nwi:Nwi_0496
- NMPDR:   fig|323098.3.peg.187
- eggNOG:   COG0744
- HOGENOM:   HBG685698
- OMA:   MMSEDGQ
- PhylomeDB:   Q3SVC8
- ProtClustDB:   PRK00056
- BioCyc:   NWIN323098:NWI_0496-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 24936; Mature: 24936

Theoretical pI: Translated: 11.03; Mature: 11.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xce20350)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAIRVMALSAIGLLLLPYLLTPLYRIGHPVSTLMIWRTLSGAPMSRQWIDFAALPPSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCC
PRSVVASEDAKFCSHQGIDWDSLREVLDDAEDGEFKRGGSTITQQVAKNLFLWPGRSMVR
CHHHHHCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHH
KALEFPLAMWIDAVLSKQRILEIYLNIAEWGPGGQFGVEAGSRYAFGRSAASLTAREAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHH
MAAILPNPVRRSARKPGPGVRRLAGTYMARARAAELRGCWSGNRSL
HHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MRRAIRVMALSAIGLLLLPYLLTPLYRIGHPVSTLMIWRTLSGAPMSRQWIDFAALPPSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCC
PRSVVASEDAKFCSHQGIDWDSLREVLDDAEDGEFKRGGSTITQQVAKNLFLWPGRSMVR
CHHHHHCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHH
KALEFPLAMWIDAVLSKQRILEIYLNIAEWGPGGQFGVEAGSRYAFGRSAASLTAREAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHH
MAAILPNPVRRSARKPGPGVRRLAGTYMARARAAELRGCWSGNRSL
HHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA