Click here to switch to the map view.

The map label for this gene is sucC

Identifier: 75674618

GI number: 75674618

Start: 471095

End: 472294

Strand: Direct

Name: sucC

Synonym: Nwi_0420

Alternate gene names: 75674618

Gene position: 471095-472294 (Clockwise)

Preceding gene: 75674617

Following gene: 75674619

Centisome position: 13.85

GC content: 62.67

Gene sequence:

>1200_bases
ATGAACATCCACGAATATCAGGCCAAGGCGTTGCTGCGCGAGTTCGGCGTGCCGGTTTCGCGAGGGGTGCCGGTGTTGCA
GGCATCGGAAGCGGAGGCCGCGGCCGAAACGCTGGGTGGTCCGGTCTGGGTGGTGAAAAGCCAGATTCACGCCGGCGGCC
GCGGCAAGGGCAAGTTCAAGGAAGCTTCCGCCGGCGAGAAAGGCGGCGTCCGCCTCGCCAGATCGATCGACGAGGTGAAG
ACCTTCGCCGGCCAGATGCTTGGCGCGACGCTGGTCACGGCGCAGACCGGCCCTGCCGGCAAGCAGGTCAACCGCCTTTA
CATCGAGGAAGGCTCCGACATCGACAAGGAATTCTACTTCTCGGCGCTGGTCGACCGCGAGACATCGAGGATTTCGTTCG
TGGTCTCCACCGAAGGCGGGATGAACATCGAGGAGGTCGCGCACAAAACGCCTGAGAAGATCGTGACCTTCTCGGTCGAT
CCCGCCACCGGCGTGATGAGCCATCACGGCCGCACCGTCGCCAGGGCGCTGAGATTGCGCGGCGATCTCGGCAAGCAGGC
GGAAAAGCTGGTGACGCAGCTTTATGATGCGTTCATCGCCAGGGACATGGCGATGCTGGAAATCAATCCGCTGGTGGTCA
CGAAACAGGGCGAGCTGCGCGTGCTCGACGCCAAGATATCGTTCGACAGCAACGCGCTGTACCGCCACTCCGATGTCGTT
GCGCTGCGCGACGAGAGCGAGGAAGACGCCAAGGAAATCGAGGCGTCGCGGTTTGATCTGAGCTACGTCGCGCTGGATGG
CCAGATCGGCTGCATGGTCAACGGCGCGGGCCTTGCCATGGCGACCATGGACATCATCAAGCTCTACGGCATGGCGCCCG
CGAACTTCCTCGACGTCGGCGGCGGCGCCACCAAGGACAAGGTCGCGGCCGCCTTCAAGATCATCACTGCCGATCCGAAC
GTGAAGGGCATCCTGATCAATATCTTCGGCGGCATCATGAAATGCGATGTCATCGCCGACGGCGTTGTCGCCGCGGTGAA
ACAGGTGGGTCTGAATGTGCCGCTGGTGGTTCGCCTCGAAGGCACCAATGTCGACGCCGGCAAGAAGATCATCCGCGAGT
CCGGCCTCAACGTGCTGCCCGCCGACGATCTCGACGATGCCGCGCAGAAGATCGTCAAAGCCGTGAAAGAGGTCGCGTGA

Upstream 100 bases:

>100_bases
TTGGAGGCATATCGTGGGCGGGGCTATCCTGGCCGACGGAAACGAATGACGGAATTGTCCCTGCCAGAACTGTCCCTGCC
GCGGGTTGGAGACCATCCAG

Downstream 100 bases:

>100_bases
TGCCGATTCTGATCGACAGGAATACGAGGGTCATCTGCCAGGGCTTCACCGGCAAGAACGGCACGTTCCATTCCGAGGCC
GCGATCGCCTACGGCACCAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNIHEYQAKALLREFGVPVSRGVPVLQASEAEAAAETLGGPVWVVKSQIHAGGRGKGKFKEASAGEKGGVRLARSIDEVK
TFAGQMLGATLVTAQTGPAGKQVNRLYIEEGSDIDKEFYFSALVDRETSRISFVVSTEGGMNIEEVAHKTPEKIVTFSVD
PATGVMSHHGRTVARALRLRGDLGKQAEKLVTQLYDAFIARDMAMLEINPLVVTKQGELRVLDAKISFDSNALYRHSDVV
ALRDESEEDAKEIEASRFDLSYVALDGQIGCMVNGAGLAMATMDIIKLYGMAPANFLDVGGGATKDKVAAAFKIITADPN
VKGILINIFGGIMKCDVIADGVVAAVKQVGLNVPLVVRLEGTNVDAGKKIIRESGLNVLPADDLDDAAQKIVKAVKEVA

Sequences:

>Translated_399_residues
MNIHEYQAKALLREFGVPVSRGVPVLQASEAEAAAETLGGPVWVVKSQIHAGGRGKGKFKEASAGEKGGVRLARSIDEVK
TFAGQMLGATLVTAQTGPAGKQVNRLYIEEGSDIDKEFYFSALVDRETSRISFVVSTEGGMNIEEVAHKTPEKIVTFSVD
PATGVMSHHGRTVARALRLRGDLGKQAEKLVTQLYDAFIARDMAMLEINPLVVTKQGELRVLDAKISFDSNALYRHSDVV
ALRDESEEDAKEIEASRFDLSYVALDGQIGCMVNGAGLAMATMDIIKLYGMAPANFLDVGGGATKDKVAAAFKIITADPN
VKGILINIFGGIMKCDVIADGVVAAVKQVGLNVPLVVRLEGTNVDAGKKIIRESGLNVLPADDLDDAAQKIVKAVKEVA
>Mature_399_residues
MNIHEYQAKALLREFGVPVSRGVPVLQASEAEAAAETLGGPVWVVKSQIHAGGRGKGKFKEASAGEKGGVRLARSIDEVK
TFAGQMLGATLVTAQTGPAGKQVNRLYIEEGSDIDKEFYFSALVDRETSRISFVVSTEGGMNIEEVAHKTPEKIVTFSVD
PATGVMSHHGRTVARALRLRGDLGKQAEKLVTQLYDAFIARDMAMLEINPLVVTKQGELRVLDAKISFDSNALYRHSDVV
ALRDESEEDAKEIEASRFDLSYVALDGQIGCMVNGAGLAMATMDIIKLYGMAPANFLDVGGGATKDKVAAAFKIITADPN
VKGILINIFGGIMKCDVIADGVVAAVKQVGLNVPLVVRLEGTNVDAGKKIIRESGLNVLPADDLDDAAQKIVKAVKEVA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=45.29262086514, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=45.8549222797927, Blast_Score=332, Evalue=5e-91,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=45.8563535911602, Blast_Score=312, Evalue=4e-85,
Organism=Escherichia coli, GI1786948, Length=396, Percent_Identity=52.020202020202, Blast_Score=399, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=47.5949367088608, Blast_Score=361, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17567829, Length=395, Percent_Identity=45.0632911392405, Blast_Score=339, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=43.6868686868687, Blast_Score=341, Evalue=1e-94,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=48.6146095717884, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI161078106, Length=404, Percent_Identity=45.5445544554455, Blast_Score=350, Evalue=7e-97,
Organism=Drosophila melanogaster, GI24645208, Length=404, Percent_Identity=45.5445544554455, Blast_Score=350, Evalue=7e-97,
Organism=Drosophila melanogaster, GI281361397, Length=405, Percent_Identity=45.679012345679, Blast_Score=348, Evalue=3e-96,
Organism=Drosophila melanogaster, GI281361395, Length=405, Percent_Identity=45.679012345679, Blast_Score=348, Evalue=3e-96,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_NITWN (Q3SVK4)

Other databases:

- EMBL:   CP000115
- RefSeq:   YP_317039.1
- HSSP:   P53590
- ProteinModelPortal:   Q3SVK4
- SMR:   Q3SVK4
- STRING:   Q3SVK4
- GeneID:   3677007
- GenomeReviews:   CP000115_GR
- KEGG:   nwi:Nwi_0420
- NMPDR:   fig|323098.3.peg.112
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- PhylomeDB:   Q3SVK4
- ProtClustDB:   PRK00696
- BioCyc:   NWIN323098:NWI_0420-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42536; Mature: 42536

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKALLREFGVPVSRGVPVLQASEAEAAAETLGGPVWVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHCCCCEEECCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
EASAGEKGGVRLARSIDEVKTFAGQMLGATLVTAQTGPAGKQVNRLYIEEGSDIDKEFYF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEECCCCCCHHHHH
SALVDRETSRISFVVSTEGGMNIEEVAHKTPEKIVTFSVDPATGVMSHHGRTVARALRLR
HHHHCCCCCEEEEEEECCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHCCHHHHHHHHHH
GDLGKQAEKLVTQLYDAFIARDMAMLEINPLVVTKQGELRVLDAKISFDSNALYRHSDVV
CCCCHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCEEEEEEEEECCCCCEEECCCEE
ALRDESEEDAKEIEASRFDLSYVALDGQIGCMVNGAGLAMATMDIIKLYGMAPANFLDVG
EECCCCHHHHHHHHHHHCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGATKDKVAAAFKIITADPNVKGILINIFGGIMKCDVIADGVVAAVKQVGLNVPLVVRLE
CCCCHHHHEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GTNVDAGKKIIRESGLNVLPADDLDDAAQKIVKAVKEVA
CCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKALLREFGVPVSRGVPVLQASEAEAAAETLGGPVWVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHCCCCEEECCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
EASAGEKGGVRLARSIDEVKTFAGQMLGATLVTAQTGPAGKQVNRLYIEEGSDIDKEFYF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEECCCCCCHHHHH
SALVDRETSRISFVVSTEGGMNIEEVAHKTPEKIVTFSVDPATGVMSHHGRTVARALRLR
HHHHCCCCCEEEEEEECCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHCCHHHHHHHHHH
GDLGKQAEKLVTQLYDAFIARDMAMLEINPLVVTKQGELRVLDAKISFDSNALYRHSDVV
CCCCHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCEEEEEEEEECCCCCEEECCCEE
ALRDESEEDAKEIEASRFDLSYVALDGQIGCMVNGAGLAMATMDIIKLYGMAPANFLDVG
EECCCCHHHHHHHHHHHCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGATKDKVAAAFKIITADPNVKGILINIFGGIMKCDVIADGVVAAVKQVGLNVPLVVRLE
CCCCHHHHEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GTNVDAGKKIIRESGLNVLPADDLDDAAQKIVKAVKEVA
CCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA