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The map label for this gene is bioC [C]

Identifier: 75674584

GI number: 75674584

Start: 430779

End: 431648

Strand: Direct

Name: bioC [C]

Synonym: Nwi_0386

Alternate gene names: 75674584

Gene position: 430779-431648 (Clockwise)

Preceding gene: 75674579

Following gene: 75674588

Centisome position: 12.66

GC content: 65.52

Gene sequence:

>870_bases
ATGGCTCCGGACTCATCTTCTTTACCGCCCGTTCTGTTCGACCGCGCTTTGCTGCGTGTGCGGCAGGAACGCGCGGCCAA
AGCGGGAGCCGTGCCGTTTCTGCTCGATCGCGTCGCGGAGGATATGGCGGAGCGGCTGAACGCCGTGTTGCGCGATCTTC
AGCACGCGGCGGATATCGGCACGCCTGGCGATCAGGTGCGCGGCGCGCTCTCGGTGCGGGTTCGGGAGCTTGCGCGGGTG
GATCTTCCGGTTGACGAGAGCGAAGCGGTGAGGCTGTCGCCGGATTCTCTTGATCTCGCCGTCTCCGGGCTTGCGTTCCA
GTTTGTCAACGATCTTCCCGGCCTGTTGGTGCAGATCCGCCGGGCCCTGAAGCCGGACGGATTGCTGCTCGCGGCCACGA
TCGGCGGCGAAACGCTGACCGAATTGCGTCAGGCGTTCGCAATGGCCGAGGCGGAGTGTGAGGGAGGCATCTCGCCGCGC
GTCGCGCCGTTCGCCGACCTTCGCGATATCGGCGCGCTGCTGCAACGCGCGGGATTCGCGCTGCCGGTGACGGATGTCGA
TCGTGTCGTAGTGCGCTACGGCGACGCCTTCGCGCTGATGCGTGACCTGCGCCGCATGGGCGCGACGAACGTTCTGACCG
CGCGGCGGCGCACGCCTTTGCGCCGCTCGACCCTGTTACGCATGGCTCAGATCTATCATGAGCGCTTCACCGATCCCGAC
GGCCGTATCCGCGCGACCTTCGATATCGTGTGGCTTTCAGGATGGGCTCCGCATGAGAGCCAGCAGAAGCCGTTGCAGCC
GGGCTCGGCGAAGGCGAGGCTTGAGGATGCGGTGAGGAACACTTCAAAAGAAAAGCCGGGCCGGGAATAA

Upstream 100 bases:

>100_bases
CGAGAGTTCCATGCCCCGAAGCTAGCGCCGGCGCGGATGAGGCTCAAGCGAACCTGCAATCGCCCCTTTTGGATGGCGAG
CGAAAAGCGTACCAAGCCGC

Downstream 100 bases:

>100_bases
GGTTTCGTCATGGCCGGGCAAAAGCGCGAAGGGCGTCTTCGCGCAGACGTCCCGGCCATCTACGTCTTGAGTTTCCAGCG
AAAAGGAAGACGTGGATGCC

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MAPDSSSLPPVLFDRALLRVRQERAAKAGAVPFLLDRVAEDMAERLNAVLRDLQHAADIGTPGDQVRGALSVRVRELARV
DLPVDESEAVRLSPDSLDLAVSGLAFQFVNDLPGLLVQIRRALKPDGLLLAATIGGETLTELRQAFAMAEAECEGGISPR
VAPFADLRDIGALLQRAGFALPVTDVDRVVVRYGDAFALMRDLRRMGATNVLTARRRTPLRRSTLLRMAQIYHERFTDPD
GRIRATFDIVWLSGWAPHESQQKPLQPGSAKARLEDAVRNTSKEKPGRE

Sequences:

>Translated_289_residues
MAPDSSSLPPVLFDRALLRVRQERAAKAGAVPFLLDRVAEDMAERLNAVLRDLQHAADIGTPGDQVRGALSVRVRELARV
DLPVDESEAVRLSPDSLDLAVSGLAFQFVNDLPGLLVQIRRALKPDGLLLAATIGGETLTELRQAFAMAEAECEGGISPR
VAPFADLRDIGALLQRAGFALPVTDVDRVVVRYGDAFALMRDLRRMGATNVLTARRRTPLRRSTLLRMAQIYHERFTDPD
GRIRATFDIVWLSGWAPHESQQKPLQPGSAKARLEDAVRNTSKEKPGRE
>Mature_288_residues
APDSSSLPPVLFDRALLRVRQERAAKAGAVPFLLDRVAEDMAERLNAVLRDLQHAADIGTPGDQVRGALSVRVRELARVD
LPVDESEAVRLSPDSLDLAVSGLAFQFVNDLPGLLVQIRRALKPDGLLLAATIGGETLTELRQAFAMAEAECEGGISPRV
APFADLRDIGALLQRAGFALPVTDVDRVVVRYGDAFALMRDLRRMGATNVLTARRRTPLRRSTLLRMAQIYHERFTDPDG
RIRATFDIVWLSGWAPHESQQKPLQPGSAKARLEDAVRNTSKEKPGRE

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40018642, Length=313, Percent_Identity=33.8658146964856, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI86792933, Length=294, Percent_Identity=34.0136054421769, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17535003, Length=193, Percent_Identity=34.7150259067358, Blast_Score=120, Evalue=6e-28,
Organism=Drosophila melanogaster, GI19922210, Length=288, Percent_Identity=37.1527777777778, Blast_Score=189, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 31756; Mature: 31625

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPDSSSLPPVLFDRALLRVRQERAAKAGAVPFLLDRVAEDMAERLNAVLRDLQHAADIG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TPGDQVRGALSVRVRELARVDLPVDESEAVRLSPDSLDLAVSGLAFQFVNDLPGLLVQIR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RALKPDGLLLAATIGGETLTELRQAFAMAEAECEGGISPRVAPFADLRDIGALLQRAGFA
HHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCC
LPVTDVDRVVVRYGDAFALMRDLRRMGATNVLTARRRTPLRRSTLLRMAQIYHERFTDPD
CCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
GRIRATFDIVWLSGWAPHESQQKPLQPGSAKARLEDAVRNTSKEKPGRE
CCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
APDSSSLPPVLFDRALLRVRQERAAKAGAVPFLLDRVAEDMAERLNAVLRDLQHAADIG
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TPGDQVRGALSVRVRELARVDLPVDESEAVRLSPDSLDLAVSGLAFQFVNDLPGLLVQIR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RALKPDGLLLAATIGGETLTELRQAFAMAEAECEGGISPRVAPFADLRDIGALLQRAGFA
HHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCC
LPVTDVDRVVVRYGDAFALMRDLRRMGATNVLTARRRTPLRRSTLLRMAQIYHERFTDPD
CCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
GRIRATFDIVWLSGWAPHESQQKPLQPGSAKARLEDAVRNTSKEKPGRE
CCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]