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The map label for this gene is ubiG

Identifier: 75674579

GI number: 75674579

Start: 427444

End: 428229

Strand: Direct

Name: ubiG

Synonym: Nwi_0381

Alternate gene names: 75674579

Gene position: 427444-428229 (Clockwise)

Preceding gene: 75674578

Following gene: 75674584

Centisome position: 12.56

GC content: 63.99

Gene sequence:

>786_bases
ATGACCATGCAAGTCGATCCTTCCGCGAATTCTTCAGCCGCGTCTTCAGCCGCACCCGGAACGACCGTCGATCGCGCCGA
GATCGAAAAATTCTCGAAGTTGTCGCAGGAATGGTGGGATCCCACCGGCAAGATGGCGCCGCTGCACAGGATCAACCCGC
TGCGGCTTCAGTTCATCCGCGACGCCGCCTGCCGCAAGTTCGATCGCAACGCCCGCAGCCTGAACTGTCTGGCGGGCCTG
CGGCTGCTCGACATCGGCTGCGGCGCGGGCCTTCTGTGCGAGCCGTTCACGCGGCTTGGCGCGCAGGTGATCGGGGTCGA
TCCTTCCGCGTCCAATATCGCCGCGGCGAAGCTCCACGCCGAGAAAGCCCATCTGTCGATCGATTATCGCTGCACCACCG
TGGAGGACATGGACGTCCGGGAGCGCTTCGACATCATCCTCGCGATGGAGGTGGTGGAGCATGTCGCCGATGTCGGGCTG
TTCCTCGATCGCTGCGCGGCGATGCTGAAGCCGGGCGGGATGATGGCGGCGTCGACCCTCAACCGCAACTGGAAGAGCTT
TGCACTGGGCATCGTCGCGGCCGAATATGTGTTGCGCTGGCTGCCGCGCGGCACGCATCAGTGGGACAAGTTCGTCACCC
CGGACGAACTGGCGCGCCACTTCGAGCGCAACGGACTCGGCATTACCGAGCAGTCCGGCGTGGTCTACAGCCCGTTCGGG
GACAGATGGAGCCTGTCATCCGACATGGACGTCAACTACATGGTGGTCGCCGAAGCGGTGGGATGA

Upstream 100 bases:

>100_bases
GATCGCCGTGGCCGCCTTTATCCGTGTCGAGGATGTTCGAGACCGTGACCACTGATACTGTTCCAGAACCCCGTCATCTC
GTCACAGGAGCCGCGCGGCA

Downstream 100 bases:

>100_bases
GGCTGCTCGTGTCATCGCCGGAAAATGCTCTAATTCCGGTCGTCCGGCGGCACTGGCAGCGACCCGACCTCGACGCCTTC
CTCGATCAGCGATTTCGCCT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTMQVDPSANSSAASSAAPGTTVDRAEIEKFSKLSQEWWDPTGKMAPLHRINPLRLQFIRDAACRKFDRNARSLNCLAGL
RLLDIGCGAGLLCEPFTRLGAQVIGVDPSASNIAAAKLHAEKAHLSIDYRCTTVEDMDVRERFDIILAMEVVEHVADVGL
FLDRCAAMLKPGGMMAASTLNRNWKSFALGIVAAEYVLRWLPRGTHQWDKFVTPDELARHFERNGLGITEQSGVVYSPFG
DRWSLSSDMDVNYMVVAEAVG

Sequences:

>Translated_261_residues
MTMQVDPSANSSAASSAAPGTTVDRAEIEKFSKLSQEWWDPTGKMAPLHRINPLRLQFIRDAACRKFDRNARSLNCLAGL
RLLDIGCGAGLLCEPFTRLGAQVIGVDPSASNIAAAKLHAEKAHLSIDYRCTTVEDMDVRERFDIILAMEVVEHVADVGL
FLDRCAAMLKPGGMMAASTLNRNWKSFALGIVAAEYVLRWLPRGTHQWDKFVTPDELARHFERNGLGITEQSGVVYSPFG
DRWSLSSDMDVNYMVVAEAVG
>Mature_260_residues
TMQVDPSANSSAASSAAPGTTVDRAEIEKFSKLSQEWWDPTGKMAPLHRINPLRLQFIRDAACRKFDRNARSLNCLAGLR
LLDIGCGAGLLCEPFTRLGAQVIGVDPSASNIAAAKLHAEKAHLSIDYRCTTVEDMDVRERFDIILAMEVVEHVADVGLF
LDRCAAMLKPGGMMAASTLNRNWKSFALGIVAAEYVLRWLPRGTHQWDKFVTPDELARHFERNGLGITEQSGVVYSPFGD
RWSLSSDMDVNYMVVAEAVG

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=242, Percent_Identity=42.5619834710744, Blast_Score=207, Evalue=7e-54,
Organism=Escherichia coli, GI1788564, Length=236, Percent_Identity=39.8305084745763, Blast_Score=182, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI115533050, Length=246, Percent_Identity=34.9593495934959, Blast_Score=150, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6324476, Length=266, Percent_Identity=28.9473684210526, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281365311, Length=261, Percent_Identity=31.8007662835249, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24585589, Length=223, Percent_Identity=34.9775784753363, Blast_Score=134, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_NITWN (Q3SVP3)

Other databases:

- EMBL:   CP000115
- RefSeq:   YP_317000.1
- ProteinModelPortal:   Q3SVP3
- SMR:   Q3SVP3
- STRING:   Q3SVP3
- GeneID:   3676966
- GenomeReviews:   CP000115_GR
- KEGG:   nwi:Nwi_0381
- NMPDR:   fig|323098.3.peg.850
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   KFITPDE
- PhylomeDB:   Q3SVP3
- ProtClustDB:   PRK05134
- BioCyc:   NWIN323098:NWI_0381-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 28745; Mature: 28614

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMQVDPSANSSAASSAAPGTTVDRAEIEKFSKLSQEWWDPTGKMAPLHRINPLRLQFIR
CCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
DAACRKFDRNARSLNCLAGLRLLDIGCGAGLLCEPFTRLGAQVIGVDPSASNIAAAKLHA
HHHHHHHHCCCCHHHHHHCCCCEEECCCCCCHHHHHHHCCCEEEECCCCCCCHHHHHHHH
EKAHLSIDYRCTTVEDMDVRERFDIILAMEVVEHVADVGLFLDRCAAMLKPGGMMAASTL
HHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
NRNWKSFALGIVAAEYVLRWLPRGTHQWDKFVTPDELARHFERNGLGITEQSGVVYSPFG
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCEEECCCC
DRWSLSSDMDVNYMVVAEAVG
CCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
TMQVDPSANSSAASSAAPGTTVDRAEIEKFSKLSQEWWDPTGKMAPLHRINPLRLQFIR
CEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
DAACRKFDRNARSLNCLAGLRLLDIGCGAGLLCEPFTRLGAQVIGVDPSASNIAAAKLHA
HHHHHHHHCCCCHHHHHHCCCCEEECCCCCCHHHHHHHCCCEEEECCCCCCCHHHHHHHH
EKAHLSIDYRCTTVEDMDVRERFDIILAMEVVEHVADVGLFLDRCAAMLKPGGMMAASTL
HHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHH
NRNWKSFALGIVAAEYVLRWLPRGTHQWDKFVTPDELARHFERNGLGITEQSGVVYSPFG
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCEEECCCC
DRWSLSSDMDVNYMVVAEAVG
CCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA