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The map label for this gene is ctaE [H]

Identifier: 75674427

GI number: 75674427

Start: 258809

End: 259663

Strand: Direct

Name: ctaE [H]

Synonym: Nwi_0228

Alternate gene names: 75674427

Gene position: 258809-259663 (Clockwise)

Preceding gene: 75674426

Following gene: 75674428

Centisome position: 7.61

GC content: 64.21

Gene sequence:

>855_bases
ATGGCTACGGCGCAAGTCAAGCACGATTACCACCTGGTCGACCCGAGTCCGTGGCCGATCGTAGGCGCGACCGCGGCTTT
CATCATGGCCGTGGGCGCGATCCTGTGGATGCATCATATGACCGCGGCCGCGCCGATCATCTTCGGCATCGGCGTGGTCG
GCGTGCTCTACACCATGGCGAGCTGGTGGGCGGATGTGATCCGCGAAGCCGAGCACAAGGGCGATCACACCCGCGTGGTG
CAGATCAGCCATCGCTATGGCATGATCCTGTTCATCACCTCCGAGGTGATGTTCTTCGTCGCCTGGTTCTGGGCCTTCTT
CAACTCCGCGCTGTTCCCGGGCGACCCCGTGCATGTGACGCGCGAGGCCCTGTTCGGCGGCGTCTGGCCGCCCAAGGGCA
TCCAGACCTTCGATCCCTGGCACCTGCCGCTGCTCAACACCCTGATCCTGCTGACCTCGGGAACCACCGTGACGTGGGCG
CACCACGCCCTGCTCAACGGCGACCGCAAGGGACTGAAGTGGGGCCTGATCCTGACCATCGCGCTCGGCGCCATCTTCAC
CTGCGTCCAGGCTTATGAGTATCAGCACGCCGCCTTCAGCTTCGCCGGCAACGTCTACGGCGCCACCTTCTTCATGGCGA
CCGGATTCCACGGCTTCCACGTGCTGGTCGGAACCATCTTCCTGATCGTCTGCCTGTTCCGCGCCAACGCGGGACACTTC
ACCCCCTCCCAGCACCTCGGCTTCGAGTTCGCCGCCTGGTACTGGCACTTCGTCGACGTGGTGTGGCTGTTCCTGTTCGT
CTGCATCTATATCTGGGGCAACGGTGCCGCCGCCATGGCCCACGCCGCACACTGA

Upstream 100 bases:

>100_bases
CTGAGCTTCGAGGGCCGACGCGTTTAGTTACCGACGCGTTTTGTTGTGAGACCAATAGGTGCCCAATACCGCCGGCACCG
CTAAGGGAGAGAGACCGCAA

Downstream 100 bases:

>100_bases
CCGCCAACCCGGCAAAAACAACAATAATCAAGGGCGGCCATAAGGCCGCCCTTTCTCTTTTCGAGCTGTCCGTCTGATTT
CTTCTTTATTTCAAGAGGCT

Product: cytochrome c oxidase, subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MATAQVKHDYHLVDPSPWPIVGATAAFIMAVGAILWMHHMTAAAPIIFGIGVVGVLYTMASWWADVIREAEHKGDHTRVV
QISHRYGMILFITSEVMFFVAWFWAFFNSALFPGDPVHVTREALFGGVWPPKGIQTFDPWHLPLLNTLILLTSGTTVTWA
HHALLNGDRKGLKWGLILTIALGAIFTCVQAYEYQHAAFSFAGNVYGATFFMATGFHGFHVLVGTIFLIVCLFRANAGHF
TPSQHLGFEFAAWYWHFVDVVWLFLFVCIYIWGNGAAAMAHAAH

Sequences:

>Translated_284_residues
MATAQVKHDYHLVDPSPWPIVGATAAFIMAVGAILWMHHMTAAAPIIFGIGVVGVLYTMASWWADVIREAEHKGDHTRVV
QISHRYGMILFITSEVMFFVAWFWAFFNSALFPGDPVHVTREALFGGVWPPKGIQTFDPWHLPLLNTLILLTSGTTVTWA
HHALLNGDRKGLKWGLILTIALGAIFTCVQAYEYQHAAFSFAGNVYGATFFMATGFHGFHVLVGTIFLIVCLFRANAGHF
TPSQHLGFEFAAWYWHFVDVVWLFLFVCIYIWGNGAAAMAHAAH
>Mature_283_residues
ATAQVKHDYHLVDPSPWPIVGATAAFIMAVGAILWMHHMTAAAPIIFGIGVVGVLYTMASWWADVIREAEHKGDHTRVVQ
ISHRYGMILFITSEVMFFVAWFWAFFNSALFPGDPVHVTREALFGGVWPPKGIQTFDPWHLPLLNTLILLTSGTTVTWAH
HALLNGDRKGLKWGLILTIALGAIFTCVQAYEYQHAAFSFAGNVYGATFFMATGFHGFHVLVGTIFLIVCLFRANAGHFT
PSQHLGFEFAAWYWHFVDVVWLFLFVCIYIWGNGAAAMAHAAH

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=268, Percent_Identity=48.5074626865672, Blast_Score=244, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6226542, Length=267, Percent_Identity=39.3258426966292, Blast_Score=187, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 31666; Mature: 31535

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAQVKHDYHLVDPSPWPIVGATAAFIMAVGAILWMHHMTAAAPIIFGIGVVGVLYTMA
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SWWADVIREAEHKGDHTRVVQISHRYGMILFITSEVMFFVAWFWAFFNSALFPGDPVHVT
HHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHH
REALFGGVWPPKGIQTFDPWHLPLLNTLILLTSGTTVTWAHHALLNGDRKGLKWGLILTI
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHCCCCCCCHHHHHHHH
ALGAIFTCVQAYEYQHAAFSFAGNVYGATFFMATGFHGFHVLVGTIFLIVCLFRANAGHF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
TPSQHLGFEFAAWYWHFVDVVWLFLFVCIYIWGNGAAAMAHAAH
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure 
ATAQVKHDYHLVDPSPWPIVGATAAFIMAVGAILWMHHMTAAAPIIFGIGVVGVLYTMA
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SWWADVIREAEHKGDHTRVVQISHRYGMILFITSEVMFFVAWFWAFFNSALFPGDPVHVT
HHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHH
REALFGGVWPPKGIQTFDPWHLPLLNTLILLTSGTTVTWAHHALLNGDRKGLKWGLILTI
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHCCCCCCCHHHHHHHH
ALGAIFTCVQAYEYQHAAFSFAGNVYGATFFMATGFHGFHVLVGTIFLIVCLFRANAGHF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
TPSQHLGFEFAAWYWHFVDVVWLFLFVCIYIWGNGAAAMAHAAH
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]