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The map label for this gene is hslV

Identifier: 74318559

GI number: 74318559

Start: 2611434

End: 2612000

Strand: Direct

Name: hslV

Synonym: Tbd_2541

Alternate gene names: 74318559

Gene position: 2611434-2612000 (Clockwise)

Preceding gene: 74318558

Following gene: 74318560

Centisome position: 89.75

GC content: 63.67

Gene sequence:

>567_bases
ATGGAACAGTATCGAGGCACCACCATCCTTTCAGTCCGTCGCGGCGCCGAAGTCGCGCTCGGCGGCGACGGCCAGGTGAC
CTTGGGCAACATCGTCATCAAGTCCACCGCGCGCAAGATTCGCCGGCTCTATCAGGAAAAGGTCCTCGCCGGTTTCGCCG
GCGGCACGGCCGACGCCTTCACGCTGTTCGAGCGCTTCGAAGCGAAGCTCGACAAGCATTCGGGGCATCTATTGCGCAGC
GCGGTCGAGCTCGCCAAGGACTGGCGCACCGATCGCATGCTGCGCCGCCTCGAGGCGATGCTCGCGGTCGCCGACCGCGA
GCATTCGCTGATCATCACCGGCAACGGCGACGTACTCGAACCCGAGCTCGGCATCGCCGCGATCGGCTCGGGCGGTGCGT
TCGCCCAGTCGGCCGCGCGGGCGCTGCTCGAGAATACGGATCTCGCGCCCCTTGAAATCGTCAAGAAGAGCCTCACCATC
GCAGGCGACATCTGCATTTATTCGAACCAGAATCACGTGATTGAAGTGCTAGGGGACAGGGGTCAGGATTCAGGGGTCAG
GGAATGA

Upstream 100 bases:

>100_bases
GCCACGTCACCCCGACTGAGCAGGCCGGGCCCCGCAGGACGCATCGGCAGGTCGCGACCGGCTCACTACGCCGGTCGCGC
AAACGCTTTTCAGGATCATC

Downstream 100 bases:

>100_bases
GCGGCCTCCGGCCGCGCCCCTAAAAGAAGCCGCGAAGCGACAACGCCCCCCTGATCCCTGAATCCTGAATCCCGGCCCCT
AAAATGACTCCCAAGGAAAT

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MEQYRGTTILSVRRGAEVALGGDGQVTLGNIVIKSTARKIRRLYQEKVLAGFAGGTADAFTLFERFEAKLDKHSGHLLRS
AVELAKDWRTDRMLRRLEAMLAVADREHSLIITGNGDVLEPELGIAAIGSGGAFAQSAARALLENTDLAPLEIVKKSLTI
AGDICIYSNQNHVIEVLGDRGQDSGVRE

Sequences:

>Translated_188_residues
MEQYRGTTILSVRRGAEVALGGDGQVTLGNIVIKSTARKIRRLYQEKVLAGFAGGTADAFTLFERFEAKLDKHSGHLLRS
AVELAKDWRTDRMLRRLEAMLAVADREHSLIITGNGDVLEPELGIAAIGSGGAFAQSAARALLENTDLAPLEIVKKSLTI
AGDICIYSNQNHVIEVLGDRGQDSGVRE
>Mature_188_residues
MEQYRGTTILSVRRGAEVALGGDGQVTLGNIVIKSTARKIRRLYQEKVLAGFAGGTADAFTLFERFEAKLDKHSGHLLRS
AVELAKDWRTDRMLRRLEAMLAVADREHSLIITGNGDVLEPELGIAAIGSGGAFAQSAARALLENTDLAPLEIVKKSLTI
AGDICIYSNQNHVIEVLGDRGQDSGVRE

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=69.0058479532164, Blast_Score=244, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_THIDA (Q3SFW2)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_316299.1
- HSSP:   P39070
- ProteinModelPortal:   Q3SFW2
- SMR:   Q3SFW2
- STRING:   Q3SFW2
- MEROPS:   T01.006
- GeneID:   3672517
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2541
- NMPDR:   fig|292415.3.peg.2614
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   Q3SFW2
- ProtClustDB:   PRK05456
- BioCyc:   TDEN292415:TBD_2541-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 20344; Mature: 20344

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: ACT_SITE 7-7

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQYRGTTILSVRRGAEVALGGDGQVTLGNIVIKSTARKIRRLYQEKVLAGFAGGTADAF
CCCCCCCEEEEEECCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
TLFERFEAKLDKHSGHLLRSAVELAKDWRTDRMLRRLEAMLAVADREHSLIITGNGDVLE
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEC
PELGIAAIGSGGAFAQSAARALLENTDLAPLEIVKKSLTIAGDICIYSNQNHVIEVLGDR
CCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEEEEEECCCCCEEEEECCC
GQDSGVRE
CCCCCCCC
>Mature Secondary Structure
MEQYRGTTILSVRRGAEVALGGDGQVTLGNIVIKSTARKIRRLYQEKVLAGFAGGTADAF
CCCCCCCEEEEEECCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
TLFERFEAKLDKHSGHLLRSAVELAKDWRTDRMLRRLEAMLAVADREHSLIITGNGDVLE
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEC
PELGIAAIGSGGAFAQSAARALLENTDLAPLEIVKKSLTIAGDICIYSNQNHVIEVLGDR
CCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEEEEEECCCCCEEEEECCC
GQDSGVRE
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA