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The map label for this gene is mtgA

Identifier: 74318523

GI number: 74318523

Start: 2577571

End: 2578269

Strand: Direct

Name: mtgA

Synonym: Tbd_2505

Alternate gene names: 74318523

Gene position: 2577571-2578269 (Clockwise)

Preceding gene: 74318522

Following gene: 74318524

Centisome position: 88.58

GC content: 64.09

Gene sequence:

>699_bases
ATGCGCACGCTATGGCGCTGGCTCGGCAAGGGCGTCGCGGCAGCCGTCGCGCTGGTGCTGCTCTACCAGCTCTGGATCTT
TGCGCACGTGTTGTGGTGGATCGACCACGATCCCCGCTCCACGGCCTTCATGGAAACGGGCCTCGCGCGCCAGCAGGCGA
AGAACCGCGACGCCGTGCTGCGCCACAAGTGGGTGCCCTACGACCGCATCTCCAATAATCTCAAGCGCGCAGTCGTCGCC
GCCGAAGACGCGCGCTTCGTCGAGCACGCCGGCTTCGACGTCGCGGGCATCCAGAAGGCGTTCCAAAAGAATGTGAAAAA
AGGCCGCCTCGTCGCCGGCGGCTCGACGATCACCCAGCAGCTCGCGAAGAACCTCTTCCTCTCCGGCGAACGCAGCTTCC
TGCGCAAAGGTCAGGAAGTCGTCATCACGCTCATGATCGAGTCGACCTGGAGCAAGCGCCGCATCCTCGAGGTCTACCTC
AACGTCATCGAATGGGGCAACGGCATCTACGGCGCCGAAGCCGCGTCACGCCGCTACTACAAGAAGTCCGCCGCGACCCT
CAGCCGCGACCAGGCTGCACGCATGGCCGCGATGATCCCGAATCCGCGCTGGTACGAGAACCACCGCGGGTCGCGGCTGT
ATCAAAGGCGGGTGGTATTGATCAAGCGGTATATGGGGAGTGTGGCGGTGCCGCGATAA

Upstream 100 bases:

>100_bases
ACGGCCTCGGCATGCTCGTCGAACAGGCGGCGGAAGCCTTCCACCTCTGGCGCGGCGTGCGCCCTGACACGGCACCGGTC
ATCGCCGCCCTGCGCGCGTG

Downstream 100 bases:

>100_bases
GTGCAGGCTTTCCGCTCCAACCCCCTATTGTGTGGACGAGAGCGCCTTCCAGTTCCCGACCGGCATAGACGAAGCTCTCA
CGCCAGACGCCAGATGCCCG

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MRTLWRWLGKGVAAAVALVLLYQLWIFAHVLWWIDHDPRSTAFMETGLARQQAKNRDAVLRHKWVPYDRISNNLKRAVVA
AEDARFVEHAGFDVAGIQKAFQKNVKKGRLVAGGSTITQQLAKNLFLSGERSFLRKGQEVVITLMIESTWSKRRILEVYL
NVIEWGNGIYGAEAASRRYYKKSAATLSRDQAARMAAMIPNPRWYENHRGSRLYQRRVVLIKRYMGSVAVPR

Sequences:

>Translated_232_residues
MRTLWRWLGKGVAAAVALVLLYQLWIFAHVLWWIDHDPRSTAFMETGLARQQAKNRDAVLRHKWVPYDRISNNLKRAVVA
AEDARFVEHAGFDVAGIQKAFQKNVKKGRLVAGGSTITQQLAKNLFLSGERSFLRKGQEVVITLMIESTWSKRRILEVYL
NVIEWGNGIYGAEAASRRYYKKSAATLSRDQAARMAAMIPNPRWYENHRGSRLYQRRVVLIKRYMGSVAVPR
>Mature_232_residues
MRTLWRWLGKGVAAAVALVLLYQLWIFAHVLWWIDHDPRSTAFMETGLARQQAKNRDAVLRHKWVPYDRISNNLKRAVVA
AEDARFVEHAGFDVAGIQKAFQKNVKKGRLVAGGSTITQQLAKNLFLSGERSFLRKGQEVVITLMIESTWSKRRILEVYL
NVIEWGNGIYGAEAASRRYYKKSAATLSRDQAARMAAMIPNPRWYENHRGSRLYQRRVVLIKRYMGSVAVPR

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=208, Percent_Identity=42.7884615384615, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI87082258, Length=162, Percent_Identity=38.2716049382716, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1786343, Length=158, Percent_Identity=38.6075949367089, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1788867, Length=208, Percent_Identity=29.3269230769231, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_THIDA (Q3SFZ8)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_316263.1
- ProteinModelPortal:   Q3SFZ8
- SMR:   Q3SFZ8
- STRING:   Q3SFZ8
- GeneID:   3671824
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2505
- NMPDR:   fig|292415.3.peg.2578
- eggNOG:   COG0744
- HOGENOM:   HBG685698
- OMA:   RISIHLK
- PhylomeDB:   Q3SFZ8
- ProtClustDB:   PRK00056
- BioCyc:   TDEN292415:TBD_2505-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 26672; Mature: 26672

Theoretical pI: Translated: 11.34; Mature: 11.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e56deac)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLWRWLGKGVAAAVALVLLYQLWIFAHVLWWIDHDPRSTAFMETGLARQQAKNRDAVL
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHH
RHKWVPYDRISNNLKRAVVAAEDARFVEHAGFDVAGIQKAFQKNVKKGRLVAGGSTITQQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCHHHHHH
LAKNLFLSGERSFLRKGQEVVITLMIESTWSKRRILEVYLNVIEWGNGIYGAEAASRRYY
HHHHHHCCCCHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KKSAATLSRDQAARMAAMIPNPRWYENHRGSRLYQRRVVLIKRYMGSVAVPR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MRTLWRWLGKGVAAAVALVLLYQLWIFAHVLWWIDHDPRSTAFMETGLARQQAKNRDAVL
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHH
RHKWVPYDRISNNLKRAVVAAEDARFVEHAGFDVAGIQKAFQKNVKKGRLVAGGSTITQQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCHHHHHH
LAKNLFLSGERSFLRKGQEVVITLMIESTWSKRRILEVYLNVIEWGNGIYGAEAASRRYY
HHHHHHCCCCHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KKSAATLSRDQAARMAAMIPNPRWYENHRGSRLYQRRVVLIKRYMGSVAVPR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA