Click here to switch to the map view.

The map label for this gene is narP [H]

Identifier: 74318482

GI number: 74318482

Start: 2537429

End: 2538094

Strand: Direct

Name: narP [H]

Synonym: Tbd_2464

Alternate gene names: 74318482

Gene position: 2537429-2538094 (Clockwise)

Preceding gene: 74318481

Following gene: 74318483

Centisome position: 87.2

GC content: 66.37

Gene sequence:

>666_bases
ATGAGCCTGACCCGCATCATCCTCGTCGACGATCACACGCTGTTCCGCAAGGGGCTCGCCGAGCTGCTCGAACAGAGCGG
CGAAATCGAGGTCACCGCCTTCACGGGCAACCCCGACGAGGTCGCGATGCTGCTTAAGGCCCATCGCCCCGACGTCCTCA
TCCTCGATCTCAACATGCCCGGGACCGACGGCATCACGCTGATGCAACAGTTGCGCAACGCGGGCTTCGCGCTGCCGATC
CTGATCCTGACGCTGTCGGAAACCGAAGACGACCTCGCGCGCGCGCTACGCGCCGGCGCGAACGGCTATCTGCTGAAAAG
CATGGAACCCGACGAGGTCGTCGACGCGATCCTGCGCGCGCAGCGCGGCGAGACCGTCGTCGCGCCCGCGATGACCGCGA
AGCTGGTCAAGCTCTACGACCAGAAGGGCCAGGACGCCGGTTCCCTGCTCGACGCGCTGACCCCGCGCGAACGCGAGATC
CTCTCGCATCTGTCACGCGGCGAGAGCAACAAGGCGATCGCGCGCACCCTCGACATCAGCCACGACACGGTCAAGCTGCA
CGTGCGCCACATCCTCGCCAAGCTCAATCTGTCGTCGCGCGTCGAGGCCGCCGTATTCGCGGTCGAACACAAGGTCGCAC
CGGGCAGCCGCAGCGACGGCCGGTAA

Upstream 100 bases:

>100_bases
ACGGCAAGCTCGTCGTCGAGTCGCGACCCGCCGGCGGCACGGTCGTGCGTCTGGTCTTTCCGCAGCGCGCCGCCTCCCAC
CAAAACAGCGAGCACGCCGC

Downstream 100 bases:

>100_bases
GCGTGCGCGCGGCCGTGCGCAAGCGCGGCCGGCCCCGAGATTCATCGCAGTCACAACAGGAGATACCGGATGTCCAGCGT
TGGCTATCATGAACCCATCG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSLTRIILVDDHTLFRKGLAELLEQSGEIEVTAFTGNPDEVAMLLKAHRPDVLILDLNMPGTDGITLMQQLRNAGFALPI
LILTLSETEDDLARALRAGANGYLLKSMEPDEVVDAILRAQRGETVVAPAMTAKLVKLYDQKGQDAGSLLDALTPREREI
LSHLSRGESNKAIARTLDISHDTVKLHVRHILAKLNLSSRVEAAVFAVEHKVAPGSRSDGR

Sequences:

>Translated_221_residues
MSLTRIILVDDHTLFRKGLAELLEQSGEIEVTAFTGNPDEVAMLLKAHRPDVLILDLNMPGTDGITLMQQLRNAGFALPI
LILTLSETEDDLARALRAGANGYLLKSMEPDEVVDAILRAQRGETVVAPAMTAKLVKLYDQKGQDAGSLLDALTPREREI
LSHLSRGESNKAIARTLDISHDTVKLHVRHILAKLNLSSRVEAAVFAVEHKVAPGSRSDGR
>Mature_220_residues
SLTRIILVDDHTLFRKGLAELLEQSGEIEVTAFTGNPDEVAMLLKAHRPDVLILDLNMPGTDGITLMQQLRNAGFALPIL
ILTLSETEDDLARALRAGANGYLLKSMEPDEVVDAILRAQRGETVVAPAMTAKLVKLYDQKGQDAGSLLDALTPREREIL
SHLSRGESNKAIARTLDISHDTVKLHVRHILAKLNLSSRVEAAVFAVEHKVAPGSRSDGR

Specific function: Could activate the expression of a formate dehydrogenase operon and could repress the transcription of the fumarate reductase (frdABCD) operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787473, Length=207, Percent_Identity=39.1304347826087, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788521, Length=212, Percent_Identity=37.2641509433962, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786747, Length=208, Percent_Identity=31.7307692307692, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=29.1866028708134, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=31.1881188118812, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788712, Length=207, Percent_Identity=24.6376811594203, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787375, Length=122, Percent_Identity=32.7868852459016, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1789809, Length=203, Percent_Identity=28.0788177339901, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=166, Percent_Identity=29.5180722891566, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788546, Length=211, Percent_Identity=28.9099526066351, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790299, Length=115, Percent_Identity=35.6521739130435, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786599, Length=115, Percent_Identity=32.1739130434783, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24113; Mature: 23982

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTRIILVDDHTLFRKGLAELLEQSGEIEVTAFTGNPDEVAMLLKAHRPDVLILDLNMP
CCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCEEEEECCCC
GTDGITLMQQLRNAGFALPILILTLSETEDDLARALRAGANGYLLKSMEPDEVVDAILRA
CCCHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
QRGETVVAPAMTAKLVKLYDQKGQDAGSLLDALTPREREILSHLSRGESNKAIARTLDIS
CCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHEEECCC
HDTVKLHVRHILAKLNLSSRVEAAVFAVEHKVAPGSRSDGR
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SLTRIILVDDHTLFRKGLAELLEQSGEIEVTAFTGNPDEVAMLLKAHRPDVLILDLNMP
CCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCEEEEECCCC
GTDGITLMQQLRNAGFALPILILTLSETEDDLARALRAGANGYLLKSMEPDEVVDAILRA
CCCHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
QRGETVVAPAMTAKLVKLYDQKGQDAGSLLDALTPREREILSHLSRGESNKAIARTLDIS
CCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHEEECCC
HDTVKLHVRHILAKLNLSSRVEAAVFAVEHKVAPGSRSDGR
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]