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The map label for this gene is grx [H]

Identifier: 74318418

GI number: 74318418

Start: 2474079

End: 2474342

Strand: Direct

Name: grx [H]

Synonym: Tbd_2400

Alternate gene names: 74318418

Gene position: 2474079-2474342 (Clockwise)

Preceding gene: 74318417

Following gene: 74318419

Centisome position: 85.03

GC content: 67.8

Gene sequence:

>264_bases
ATGGCTAAAGTCGTGATGTACTGCACCGCCGTCTGCCCGTATTGCGTCGCCGCCGAGCGGCTGCTGAAAAGCCGCGGCGT
CGCCGAAATCGAAAAGATTCGCGTCGACCTCGACCCCTCCCGCATGGACGAGATGATCGAGCGCTCGGGCGGGCGCCGTA
CCGTGCCCCAGGTGTTCATCGGCGACACCCACGTCGGCGGCTTCGACGACACCTCCGCGCTCGACGCGGCCGGCGAGCTG
CTGCCGTTGCTCGCGCGCGACTGA

Upstream 100 bases:

>100_bases
CCTGAAGAAGGCCGGTTTCGAATCCGTGTACAACCAGGCCGGCGGCATCCTCGCGTGGGAACGCGCCAATCTTCCGGTCA
CTCAGAAATAAGGAGCCCCC

Downstream 100 bases:

>100_bases
CCGCAGCGGCGGGCGCCACTTGAATTTTCCGGCGCCTTCCCCCACCTTGAAGCGAAGCCCTTTCGTTTCGAGGACGCCGC
CATGGAACTCGCCTGCCCCC

Product: glutaredoxin, GrxC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 86

Protein sequence:

>87_residues
MAKVVMYCTAVCPYCVAAERLLKSRGVAEIEKIRVDLDPSRMDEMIERSGGRRTVPQVFIGDTHVGGFDDTSALDAAGEL
LPLLARD

Sequences:

>Translated_87_residues
MAKVVMYCTAVCPYCVAAERLLKSRGVAEIEKIRVDLDPSRMDEMIERSGGRRTVPQVFIGDTHVGGFDDTSALDAAGEL
LPLLARD
>Mature_86_residues
AKVVMYCTAVCPYCVAAERLLKSRGVAEIEKIRVDLDPSRMDEMIERSGGRRTVPQVFIGDTHVGGFDDTSALDAAGELL
PLLARD

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=84, Percent_Identity=50, Blast_Score=80, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9498; Mature: 9367

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVVMYCTAVCPYCVAAERLLKSRGVAEIEKIRVDLDPSRMDEMIERSGGRRTVPQVFI
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEE
GDTHVGGFDDTSALDAAGELLPLLARD
CCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKVVMYCTAVCPYCVAAERLLKSRGVAEIEKIRVDLDPSRMDEMIERSGGRRTVPQVFI
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEE
GDTHVGGFDDTSALDAAGELLPLLARD
CCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]