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The map label for this gene is ompR [H]

Identifier: 74318372

GI number: 74318372

Start: 2428761

End: 2429468

Strand: Reverse

Name: ompR [H]

Synonym: Tbd_2354

Alternate gene names: 74318372

Gene position: 2429468-2428761 (Counterclockwise)

Preceding gene: 74318376

Following gene: 74318371

Centisome position: 83.49

GC content: 67.51

Gene sequence:

>708_bases
ATGGGAAAAGAGACGATCTACGTCACCGATGACGACCGTGGCATCCGCGAGCTCGTCGCCGAATACCTGACGAGCCAGGG
CTACGCGGTCGAGACCGCCGAGGACGCCGCGGCGCTCGATCGCCTGCTCGCGGCGCGCCTGCCCGACCTCGTCGTGCTCG
ACTGGATGATGCCCGGCGAAGACGGCCTGTCGGTCGCGCGGCGGCTACGCGCGCGGCCGGGTTTTCCGCCGATCATCATG
CTGTCGGCCAAGGGCGAGGACATCGACCGCATCATCGGGCTCGAGGTCGGTGCCGACGACTACCTGCCCAAGCCCTTCAA
TCCGCGTGAACTGCTGGCGCGGATCCGGGCCGTGTTGCGTCGCCAGCCCACCGCCGCCGAGCCGACCGAAAGCGCGCGCC
TGGTCCGCTTCGGACCTTTCAGCGTCAATCTCGACGCCCGCATGCTGAGCCGGGATGGGGTCGAAATCCCGCTCACCGGC
GGCGAATACGAGTTGCTCGAAATCTTCGTCAGGCACGCCAACCGCGCCTTGTCACGCGACTGGCTCATGGATCAGCTGCG
CGGCTTCGAGCGCGACCCGTTCGACCGCAGCATCGACGTGCGGGTCAACCGCCTGCGCAAGAAAATCGAGGACGACCCGA
CGAACCCCGCCTACATCCGCACCCAGCGCGGGCAGGGTTATCTGTTCGTGCCCCAGGGCAAGGGCTGA

Upstream 100 bases:

>100_bases
GTTGAGGGGAGTAAGCGCCCTGTTTCAGGCAGGGACGATTTTGTAACAGTGTGTAACCGCCGTGGGAAGCGGTGCTCCGT
GCCGCTGATATAGTTGCCGC

Downstream 100 bases:

>100_bases
CGCCCGGCGATGGTACGCATCGCCAGTTCGCTCTACGCGCGCACGGCGCTGACGCTGGCCATCGCTTTCGTCCTCTTTCA
GGCCGCCGCCTTCGCGGTCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MGKETIYVTDDDRGIRELVAEYLTSQGYAVETAEDAAALDRLLAARLPDLVVLDWMMPGEDGLSVARRLRARPGFPPIIM
LSAKGEDIDRIIGLEVGADDYLPKPFNPRELLARIRAVLRRQPTAAEPTESARLVRFGPFSVNLDARMLSRDGVEIPLTG
GEYELLEIFVRHANRALSRDWLMDQLRGFERDPFDRSIDVRVNRLRKKIEDDPTNPAYIRTQRGQGYLFVPQGKG

Sequences:

>Translated_235_residues
MGKETIYVTDDDRGIRELVAEYLTSQGYAVETAEDAAALDRLLAARLPDLVVLDWMMPGEDGLSVARRLRARPGFPPIIM
LSAKGEDIDRIIGLEVGADDYLPKPFNPRELLARIRAVLRRQPTAAEPTESARLVRFGPFSVNLDARMLSRDGVEIPLTG
GEYELLEIFVRHANRALSRDWLMDQLRGFERDPFDRSIDVRVNRLRKKIEDDPTNPAYIRTQRGQGYLFVPQGKG
>Mature_234_residues
GKETIYVTDDDRGIRELVAEYLTSQGYAVETAEDAAALDRLLAARLPDLVVLDWMMPGEDGLSVARRLRARPGFPPIIML
SAKGEDIDRIIGLEVGADDYLPKPFNPRELLARIRAVLRRQPTAAEPTESARLVRFGPFSVNLDARMLSRDGVEIPLTGG
EYELLEIFVRHANRALSRDWLMDQLRGFERDPFDRSIDVRVNRLRKKIEDDPTNPAYIRTQRGQGYLFVPQGKG

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=51.9480519480519, Blast_Score=237, Evalue=5e-64,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=38.3620689655172, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=34.3612334801762, Blast_Score=144, Evalue=3e-36,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=38.4279475982533, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=33.1877729257642, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=38.2608695652174, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=36.6071428571429, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=35, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=35.6828193832599, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=34.070796460177, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=35.8078602620087, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=33.920704845815, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=35.9307359307359, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=30.6306306306306, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790299, Length=234, Percent_Identity=24.3589743589744, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788550, Length=159, Percent_Identity=26.4150943396226, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26578; Mature: 26447

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKETIYVTDDDRGIRELVAEYLTSQGYAVETAEDAAALDRLLAARLPDLVVLDWMMPGE
CCCCEEEEECCCCCHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCEEEEEECCCCC
DGLSVARRLRARPGFPPIIMLSAKGEDIDRIIGLEVGADDYLPKPFNPRELLARIRAVLR
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RQPTAAEPTESARLVRFGPFSVNLDARMLSRDGVEIPLTGGEYELLEIFVRHANRALSRD
CCCCCCCCCCCCEEEEECCEEECCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
WLMDQLRGFERDPFDRSIDVRVNRLRKKIEDDPTNPAYIRTQRGQGYLFVPQGKG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCC
>Mature Secondary Structure 
GKETIYVTDDDRGIRELVAEYLTSQGYAVETAEDAAALDRLLAARLPDLVVLDWMMPGE
CCCEEEEECCCCCHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCEEEEEECCCCC
DGLSVARRLRARPGFPPIIMLSAKGEDIDRIIGLEVGADDYLPKPFNPRELLARIRAVLR
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RQPTAAEPTESARLVRFGPFSVNLDARMLSRDGVEIPLTGGEYELLEIFVRHANRALSRD
CCCCCCCCCCCCEEEEECCEEECCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
WLMDQLRGFERDPFDRSIDVRVNRLRKKIEDDPTNPAYIRTQRGQGYLFVPQGKG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]