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The map label for this gene is phnN [H]

Identifier: 74318307

GI number: 74318307

Start: 2364069

End: 2364641

Strand: Reverse

Name: phnN [H]

Synonym: Tbd_2289

Alternate gene names: 74318307

Gene position: 2364641-2364069 (Counterclockwise)

Preceding gene: 74318308

Following gene: 74318306

Centisome position: 81.26

GC content: 63.35

Gene sequence:

>573_bases
ATGTCTGAAGGGAAACTGTTCTACGTCATCGGCCCTTCCGGCAGTGGCAAGGACAGCCTGATGCGCTACGGCCGCGAGCG
TCTCGCCGGCGACCCCGGCGTTGTCTTCGCCCACCGCTACATCACGCGGCCGGTGGAACTTCACGGGGAGAATCACGTCG
CCCTGACCGAGGACGAATTCGATGCCCGCCTCGCTACCGGCCTCTTCGCCCTGCACTGGGACAGCCACGGCCTGCGCTAC
GGCATCGGCCGGGAAATCAACCTTTGGCTGGCCAAGGGCTGCAACGTGGTGTTGAACGGCTCGCGCGAATACCTGCCAGA
GGCAAGGCGCCGCTACCCGGGGTTGACCGCGATTCTGGTCAACGTTTCGCCCGAAGTTCTTGCCGAGAGACTGCGCGCCC
GTGGCCGGGAAACGGAAGATCAGATATCCCGGCGGGTCGCACGCGCGAAGCAATTCATGCACCCTGAGGGGCGCCTGGAA
GTCATTGCGAACGACGCTGAATTGCACGTAGCCGGTGAACGCTTGGTACAGTTGTTGTCGGACGCCGACGCTTCCAAACG
AGCGTTTGCCTGA

Upstream 100 bases:

>100_bases
AGGCGCGCCGATCTGGTCGCCGTCGCCCACATCAACGGGCTGGCCCAAGCGAGCAGCGTGTTTTCGGCGGGCAAGCCGGT
CTTCGAAGCCCGTTTCGACC

Downstream 100 bases:

>100_bases
CATGCGCGTGACGTTTCTCGGTACGGGTGCCGCAGGCGGTGTGCCGCTTTACGGCTGCGATTGTCCGGCTTGCACGCGAG
CGCGGGCGGTGGTCGACTTT

Product: guanylate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSEGKLFYVIGPSGSGKDSLMRYGRERLAGDPGVVFAHRYITRPVELHGENHVALTEDEFDARLATGLFALHWDSHGLRY
GIGREINLWLAKGCNVVLNGSREYLPEARRRYPGLTAILVNVSPEVLAERLRARGRETEDQISRRVARAKQFMHPEGRLE
VIANDAELHVAGERLVQLLSDADASKRAFA

Sequences:

>Translated_190_residues
MSEGKLFYVIGPSGSGKDSLMRYGRERLAGDPGVVFAHRYITRPVELHGENHVALTEDEFDARLATGLFALHWDSHGLRY
GIGREINLWLAKGCNVVLNGSREYLPEARRRYPGLTAILVNVSPEVLAERLRARGRETEDQISRRVARAKQFMHPEGRLE
VIANDAELHVAGERLVQLLSDADASKRAFA
>Mature_189_residues
SEGKLFYVIGPSGSGKDSLMRYGRERLAGDPGVVFAHRYITRPVELHGENHVALTEDEFDARLATGLFALHWDSHGLRYG
IGREINLWLAKGCNVVLNGSREYLPEARRRYPGLTAILVNVSPEVLAERLRARGRETEDQISRRVARAKQFMHPEGRLEV
IANDAELHVAGERLVQLLSDADASKRAFA

Specific function: Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known [H]

COG id: COG3709

COG function: function code P; Uncharacterized component of phosphonate metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790532, Length=177, Percent_Identity=45.1977401129944, Blast_Score=146, Evalue=7e-37,
Organism=Escherichia coli, GI1790080, Length=153, Percent_Identity=32.6797385620915, Blast_Score=73, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008144
- InterPro:   IPR008145
- InterPro:   IPR012699 [H]

Pfam domain/function: PF00625 Guanylate_kin [H]

EC number: NA

Molecular weight: Translated: 21260; Mature: 21129

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50052 GUANYLATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGKLFYVIGPSGSGKDSLMRYGRERLAGDPGVVFAHRYITRPVELHGENHVALTEDEF
CCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHCCCCEECCCCCEEECCCHH
DARLATGLFALHWDSHGLRYGIGREINLWLAKGCNVVLNGSREYLPEARRRYPGLTAILV
HHHHHHCEEEEEECCCCCEECCCCEEEEEEECCCCEEECCCHHHHHHHHHHCCCEEEEEE
NVSPEVLAERLRARGRETEDQISRRVARAKQFMHPEGRLEVIANDAELHVAGERLVQLLS
ECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEHHHHHHHHHH
DADASKRAFA
CCCCCCCCCC
>Mature Secondary Structure 
SEGKLFYVIGPSGSGKDSLMRYGRERLAGDPGVVFAHRYITRPVELHGENHVALTEDEF
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHCCCCEECCCCCEEECCCHH
DARLATGLFALHWDSHGLRYGIGREINLWLAKGCNVVLNGSREYLPEARRRYPGLTAILV
HHHHHHCEEEEEECCCCCEECCCCEEEEEEECCCCEEECCCHHHHHHHHHHCCCEEEEEE
NVSPEVLAERLRARGRETEDQISRRVARAKQFMHPEGRLEVIANDAELHVAGERLVQLLS
ECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEHHHHHHHHHH
DADASKRAFA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155230; 1840580; 7610040; 9278503 [H]