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The map label for this gene is gfo [H]

Identifier: 74318276

GI number: 74318276

Start: 2332363

End: 2333529

Strand: Reverse

Name: gfo [H]

Synonym: Tbd_2258

Alternate gene names: 74318276

Gene position: 2333529-2332363 (Counterclockwise)

Preceding gene: 74318277

Following gene: 74318275

Centisome position: 80.2

GC content: 67.35

Gene sequence:

>1167_bases
ATGGCTCGTACAAGCAAGCGGGCGGCGACTGCCCCCGGGGTGAAGGCCGCGCCGCGACGCGGCAGAAAGATCCGCTACGC
CGTCGTCGGCCTCGGCTACATCGCGCAGATCGCCGTGCTGCCGGCTTTTGCCCAGGCCGCGAAGAACGCCGAACTCGCGG
CGCTGGTGTCGGATGACCCGGTCAAGCTCAAGAAGCTGGCGAAGCAATACGGCGTCCCGCGCGTCGCGAGCTACGCGGAA
TACGACGCGCTGCTGGCGAGCGGCGAGATCGACGCCGTCTACATCGCGCTGCCCAACCACCTGCACCTCGATTACACATT
GCGCGCGGCGCGCGCCGGGGTGCACGTGCTGTGCGAAAAACCGATGGCGGTGACCGAGGCCGAATGCCGGCGCATGACGC
GTGAATGCGAAAAGCGCGGGGTCAAGCTGATGATCGCCTACCGTCTGCACTTCGAGAAGGCGAATCTCGCGGCGGCCGAA
CTCGTCAATTCGGGCAAGCTCGGCGACGCGCGGATTTTCAATTCGGTGTTCACGATGCAGGTCAACGATCCCGACAACAT
CCGCCTGCAGGACGAAACCGGCGGCGGGGTGCTCTACGACATCGGCGTCTACTGCATCAACGCTGCGCGTTACCTGTTTC
GCGACGAGCCGACCGAGGTCTTCGCGGCGACGGCGCGCAAGCCGGACGCGCGCTTCGACGAGGTCGAGGAGATGGCGAGC
GCGCTCATGCGCTTTCCGGGCGACCGCCTCGCGAGCTTCACCGCGAGCTTCGGCGCGGCCCGCGGCTCGTCCTACGAGGT
CGTCGGCACCAAGGGTTCATTGCGCGTCGCGCCCGCCTACGGTTACGCCGAGGATCTCAAACACGTCGTGACGATCGGCG
GCAAGACGCGGGAGCGCGTGTTTCCGCGCGGCGACCAGTTCGCCCCGCAACTGCTCTATTTCTCCGATTGCATCCTGCAG
GACCGGACGCCCGAGCCTTCGGGCGAGGAGGGCCGGCTCGACGTGCGCATTATCGAGGCGCTCTACCGCTCGGCCAAAAT
CGGAAAGCTCGTCCGCCTCGCGCCCGCCGGCAAGGTGGAGCGGCCCGACAGCGATCAGGAACGCTCGCGGCCGCCGATCG
ACAAACCGCGGCTCGTGCGCGCCCGCGCGCCATCTGACAAGGGCTAG

Upstream 100 bases:

>100_bases
GGCGAAGAAGGGGGCGCAGACGCGTGCGCGCAACGCCGCGAAAAGGAAGGCCGCTTCCTGAGCGGCCGTCGCCGCCTGCA
GCGCATCGAGGAGATTCCGT

Downstream 100 bases:

>100_bases
GCTGCGCCTGCAGCGCTCGCGTCGGTCGGAGAATCCCTACACGGCCCCCTCCGGCCCGCTCACGCCTTTCTCAGTACAAC
CGGATTTCGCGCCCCGGGGC

Product: putative glucose-fructose oxidoreductase protein

Products: NA

Alternate protein names: GFOR [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MARTSKRAATAPGVKAAPRRGRKIRYAVVGLGYIAQIAVLPAFAQAAKNAELAALVSDDPVKLKKLAKQYGVPRVASYAE
YDALLASGEIDAVYIALPNHLHLDYTLRAARAGVHVLCEKPMAVTEAECRRMTRECEKRGVKLMIAYRLHFEKANLAAAE
LVNSGKLGDARIFNSVFTMQVNDPDNIRLQDETGGGVLYDIGVYCINAARYLFRDEPTEVFAATARKPDARFDEVEEMAS
ALMRFPGDRLASFTASFGAARGSSYEVVGTKGSLRVAPAYGYAEDLKHVVTIGGKTRERVFPRGDQFAPQLLYFSDCILQ
DRTPEPSGEEGRLDVRIIEALYRSAKIGKLVRLAPAGKVERPDSDQERSRPPIDKPRLVRARAPSDKG

Sequences:

>Translated_388_residues
MARTSKRAATAPGVKAAPRRGRKIRYAVVGLGYIAQIAVLPAFAQAAKNAELAALVSDDPVKLKKLAKQYGVPRVASYAE
YDALLASGEIDAVYIALPNHLHLDYTLRAARAGVHVLCEKPMAVTEAECRRMTRECEKRGVKLMIAYRLHFEKANLAAAE
LVNSGKLGDARIFNSVFTMQVNDPDNIRLQDETGGGVLYDIGVYCINAARYLFRDEPTEVFAATARKPDARFDEVEEMAS
ALMRFPGDRLASFTASFGAARGSSYEVVGTKGSLRVAPAYGYAEDLKHVVTIGGKTRERVFPRGDQFAPQLLYFSDCILQ
DRTPEPSGEEGRLDVRIIEALYRSAKIGKLVRLAPAGKVERPDSDQERSRPPIDKPRLVRARAPSDKG
>Mature_387_residues
ARTSKRAATAPGVKAAPRRGRKIRYAVVGLGYIAQIAVLPAFAQAAKNAELAALVSDDPVKLKKLAKQYGVPRVASYAEY
DALLASGEIDAVYIALPNHLHLDYTLRAARAGVHVLCEKPMAVTEAECRRMTRECEKRGVKLMIAYRLHFEKANLAAAEL
VNSGKLGDARIFNSVFTMQVNDPDNIRLQDETGGGVLYDIGVYCINAARYLFRDEPTEVFAATARKPDARFDEVEEMASA
LMRFPGDRLASFTASFGAARGSSYEVVGTKGSLRVAPAYGYAEDLKHVVTIGGKTRERVFPRGDQFAPQLLYFSDCILQD
RTPEPSGEEGRLDVRIIEALYRSAKIGKLVRLAPAGKVERPDSDQERSRPPIDKPRLVRARAPSDKG

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=257, Percent_Identity=28.0155642023346, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI87082405, Length=281, Percent_Identity=24.9110320284698, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787574, Length=352, Percent_Identity=25.2840909090909, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87081947, Length=254, Percent_Identity=26.7716535433071, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI145693182, Length=209, Percent_Identity=29.1866028708134, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24581117, Length=282, Percent_Identity=25.531914893617, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008354
- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.99.28 [H]

Molecular weight: Translated: 42574; Mature: 42443

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTSKRAATAPGVKAAPRRGRKIRYAVVGLGYIAQIAVLPAFAQAAKNAELAALVSDDP
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
VKLKKLAKQYGVPRVASYAEYDALLASGEIDAVYIALPNHLHLDYTLRAARAGVHVLCEK
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEHHHHHCCEEEEECC
PMAVTEAECRRMTRECEKRGVKLMIAYRLHFEKANLAAAELVNSGKLGDARIFNSVFTMQ
CCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHHHCCCCCCCHHEECEEEEEE
VNDPDNIRLQDETGGGVLYDIGVYCINAARYLFRDEPTEVFAATARKPDARFDEVEEMAS
ECCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHH
ALMRFPGDRLASFTASFGAARGSSYEVVGTKGSLRVAPAYGYAEDLKHVVTIGGKTRERV
HHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCHHHHHHHEECCCCHHHHC
FPRGDQFAPQLLYFSDCILQDRTPEPSGEEGRLDVRIIEALYRSAKIGKLVRLAPAGKVE
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCC
RPDSDQERSRPPIDKPRLVRARAPSDKG
CCCCHHHHCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
ARTSKRAATAPGVKAAPRRGRKIRYAVVGLGYIAQIAVLPAFAQAAKNAELAALVSDDP
CCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
VKLKKLAKQYGVPRVASYAEYDALLASGEIDAVYIALPNHLHLDYTLRAARAGVHVLCEK
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEHHHHHCCEEEEECC
PMAVTEAECRRMTRECEKRGVKLMIAYRLHFEKANLAAAELVNSGKLGDARIFNSVFTMQ
CCCCCHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHHHCCCCCCCHHEECEEEEEE
VNDPDNIRLQDETGGGVLYDIGVYCINAARYLFRDEPTEVFAATARKPDARFDEVEEMAS
ECCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHH
ALMRFPGDRLASFTASFGAARGSSYEVVGTKGSLRVAPAYGYAEDLKHVVTIGGKTRERV
HHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCHHHHHHHEECCCCHHHHC
FPRGDQFAPQLLYFSDCILQDRTPEPSGEEGRLDVRIIEALYRSAKIGKLVRLAPAGKVE
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCC
RPDSDQERSRPPIDKPRLVRARAPSDKG
CCCCHHHHCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1537789; 8472911; 8994968 [H]