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The map label for this gene is perM [H]

Identifier: 74318271

GI number: 74318271

Start: 2327338

End: 2328507

Strand: Reverse

Name: perM [H]

Synonym: Tbd_2253

Alternate gene names: 74318271

Gene position: 2328507-2327338 (Counterclockwise)

Preceding gene: 74318272

Following gene: 74318270

Centisome position: 80.02

GC content: 66.41

Gene sequence:

>1170_bases
ATGGACGAGAACAAACCTGCCAGCCCGGTGACTGCTGCCCGCGATGCGCAGTGCGACGTTGACACGCCGGCCGTACAGCT
CTCCGGCGAAAACCGCAACGGGCCGCTTCTGTTGCTCAGCGTGCTGTCGACGGTGTTCGTGCTCGACTGGGCGCAGGCCG
TGTTCATCCCGCTCGTGCTCGCCGTCATCATCAGTTACGCGCTGGCGCCGCCCATGCGTCTGCTCGGCCGGCTGCACGTG
CCGCAGATCGTCGGCGCGTCGCTGCTGCTGGCGCTGATCGTCGGTGCGGGCGGATCGCTCGCGTATTCGCTGCGCGACGA
GGCCATCGGAATGATCGAAACCCTGCCGCAGGCGGCGAAAAAACTGCGCCGCACCGTGCAGAAGGAGATTGCAGGGCTCG
AAAGCGGCGCGATCGGCAACGTCCAGGAAGCGGCCAGCCAGATCGAGCGCGCGGCGCGCGAAACCGCGTCCGATCCGGTC
GTCCCGCGCGGCGTGACGCGCGTGCAGATCGAAGAGCCGCGCTTCCGCCTCGAGGACTATCTGTGGAACGGTACGCTCGG
CGCCCTCTCGATCGTGAGCCTCGCGGTCATGGTGCTCTTCCTCGCCTTTTTCATGATGATTTCCGGCGACACCTACCGCC
GCAAGCTGGTGCAGATTTCGGGCCCCGCGTTCAGCAAAAAGAAGATAACGCTGCAGGTGCTGAACGAAATCAGCGTGCAG
ATCCAGCGCTACCTGCTGGTGCAGGCCTTCGCCGGCGCCATCGTCGGCCTCGCCACCTGGGCCGCGTTCAGCTGGCTCGG
CGTCGAGCACGCGGCGCTCTGGGGCGTCGTCGCCGGGGTGCTCAACATCATTCCCTATCTCGGCGCGGTGATCGTCGCCG
GCGGGGCGGCGCTGGTCGGGCTGCTGCAATTCGGCAGCGTGAGCACGGCGCTGACGGTCGGCGGCGTTTCGCTCGTCATC
AACAGCCTCGAGGGCTACCTCCTCATGCCCTGGCTCACCGGCCGCGCCAACCGCATGAACGCGGTCGTGATCTTCATCGG
CGTGCTGTTCTGGGGCTGGCTGTGGGGCGCCTGGGGGCTGCTGCTCGGCATGCCGATCATGATCGCGATCAAGGCGATCT
GCGACCACATCGAGGACTTCAGGTCGATAGGCGAACTGTTGGGCGACTGA

Upstream 100 bases:

>100_bases
CGCTGATCGAAGCGAACACTGCGGAAGACAGCGCGTGCCGCCGCCTGATCGCCGAGGCCCGGCAGTCGCCCTGACCCCCG
CCGAGAAAAGGGGCGCGAAC

Downstream 100 bases:

>100_bases
GTGTCCGACAGCGCCTTCCCTCAACAAGGCTTCGCCGATTCCTACACCCTAAAGCGCGGCGGGCCGATGGGCGGAAACCC
GCGCCGCTCGTAGAGTTCCA

Product: putative permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MDENKPASPVTAARDAQCDVDTPAVQLSGENRNGPLLLLSVLSTVFVLDWAQAVFIPLVLAVIISYALAPPMRLLGRLHV
PQIVGASLLLALIVGAGGSLAYSLRDEAIGMIETLPQAAKKLRRTVQKEIAGLESGAIGNVQEAASQIERAARETASDPV
VPRGVTRVQIEEPRFRLEDYLWNGTLGALSIVSLAVMVLFLAFFMMISGDTYRRKLVQISGPAFSKKKITLQVLNEISVQ
IQRYLLVQAFAGAIVGLATWAAFSWLGVEHAALWGVVAGVLNIIPYLGAVIVAGGAALVGLLQFGSVSTALTVGGVSLVI
NSLEGYLLMPWLTGRANRMNAVVIFIGVLFWGWLWGAWGLLLGMPIMIAIKAICDHIEDFRSIGELLGD

Sequences:

>Translated_389_residues
MDENKPASPVTAARDAQCDVDTPAVQLSGENRNGPLLLLSVLSTVFVLDWAQAVFIPLVLAVIISYALAPPMRLLGRLHV
PQIVGASLLLALIVGAGGSLAYSLRDEAIGMIETLPQAAKKLRRTVQKEIAGLESGAIGNVQEAASQIERAARETASDPV
VPRGVTRVQIEEPRFRLEDYLWNGTLGALSIVSLAVMVLFLAFFMMISGDTYRRKLVQISGPAFSKKKITLQVLNEISVQ
IQRYLLVQAFAGAIVGLATWAAFSWLGVEHAALWGVVAGVLNIIPYLGAVIVAGGAALVGLLQFGSVSTALTVGGVSLVI
NSLEGYLLMPWLTGRANRMNAVVIFIGVLFWGWLWGAWGLLLGMPIMIAIKAICDHIEDFRSIGELLGD
>Mature_389_residues
MDENKPASPVTAARDAQCDVDTPAVQLSGENRNGPLLLLSVLSTVFVLDWAQAVFIPLVLAVIISYALAPPMRLLGRLHV
PQIVGASLLLALIVGAGGSLAYSLRDEAIGMIETLPQAAKKLRRTVQKEIAGLESGAIGNVQEAASQIERAARETASDPV
VPRGVTRVQIEEPRFRLEDYLWNGTLGALSIVSLAVMVLFLAFFMMISGDTYRRKLVQISGPAFSKKKITLQVLNEISVQ
IQRYLLVQAFAGAIVGLATWAAFSWLGVEHAALWGVVAGVLNIIPYLGAVIVAGGAALVGLLQFGSVSTALTVGGVSLVI
NSLEGYLLMPWLTGRANRMNAVVIFIGVLFWGWLWGAWGLLLGMPIMIAIKAICDHIEDFRSIGELLGD

Specific function: Unknown

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1788838, Length=339, Percent_Identity=26.8436578171091, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787885, Length=150, Percent_Identity=34.6666666666667, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082271, Length=348, Percent_Identity=25, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 41634; Mature: 41634

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDENKPASPVTAARDAQCDVDTPAVQLSGENRNGPLLLLSVLSTVFVLDWAQAVFIPLVL
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVIISYALAPPMRLLGRLHVPQIVGASLLLALIVGAGGSLAYSLRDEAIGMIETLPQAAK
HHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHH
KLRRTVQKEIAGLESGAIGNVQEAASQIERAARETASDPVVPRGVTRVQIEEPRFRLEDY
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHH
LWNGTLGALSIVSLAVMVLFLAFFMMISGDTYRRKLVQISGPAFSKKKITLQVLNEISVQ
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
IQRYLLVQAFAGAIVGLATWAAFSWLGVEHAALWGVVAGVLNIIPYLGAVIVAGGAALVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQFGSVSTALTVGGVSLVINSLEGYLLMPWLTGRANRMNAVVIFIGVLFWGWLWGAWGL
HHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLGMPIMIAIKAICDHIEDFRSIGELLGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDENKPASPVTAARDAQCDVDTPAVQLSGENRNGPLLLLSVLSTVFVLDWAQAVFIPLVL
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVIISYALAPPMRLLGRLHVPQIVGASLLLALIVGAGGSLAYSLRDEAIGMIETLPQAAK
HHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHH
KLRRTVQKEIAGLESGAIGNVQEAASQIERAARETASDPVVPRGVTRVQIEEPRFRLEDY
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHH
LWNGTLGALSIVSLAVMVLFLAFFMMISGDTYRRKLVQISGPAFSKKKITLQVLNEISVQ
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
IQRYLLVQAFAGAIVGLATWAAFSWLGVEHAALWGVVAGVLNIIPYLGAVIVAGGAALVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQFGSVSTALTVGGVSLVINSLEGYLLMPWLTGRANRMNAVVIFIGVLFWGWLWGAWGL
HHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLGMPIMIAIKAICDHIEDFRSIGELLGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]