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The map label for this gene is nusB

Identifier: 74318210

GI number: 74318210

Start: 2273647

End: 2274084

Strand: Direct

Name: nusB

Synonym: Tbd_2192

Alternate gene names: 74318210

Gene position: 2273647-2274084 (Clockwise)

Preceding gene: 74318209

Following gene: 74318211

Centisome position: 78.14

GC content: 63.93

Gene sequence:

>438_bases
ATGGCCGGCTCCCGCAAGGTCGCGCGCGAATTCACGCTGCAGGGCATCTACGCCTGGATGATCGGCGGCGCCGACGTCAC
GCTCATCGCCGCGAATCTCAAAGAGGACGAACAGTTCAAGCGCGCCGACGAAGCCTACTTCCGCACCCTGCTCTACGGCG
TGCTCAAGGAAGAGGACATGCTGAGCTCGCGCATCGCGCCGCTGCTCGACCGCGCGGTCGCCGAGCTCTCGCCGATCGAG
CGCTCCATCCTGCTGATCGGCGCCTACGAGCTGCTGCACTGCCCCGACGTCCCCTGGCGCGTCGCGATCAACGAAAGCGT
CGAGCTGGCGAAGAAGTTCGGCGGCACCGACGGCCATAAATACATCAACGGCGTGCTCGACAAACTCGCGCAGGATGTGC
GCGCGGTGGAGATCGAGCATGCAAAAAAAAGGGATTAG

Upstream 100 bases:

>100_bases
CCGTCGACACCGAGGAGCAGGCGCACGTGCGCATGGCCGAAAAAGGCCGCGACGCCGCGCGCGTAGCGGTCGAGATGGCC
AACCTGCTGAAGCGTCTCTG

Downstream 100 bases:

>100_bases
GGATCGGGATTCAGGGGTCAGGGAAAAGCGAGTCCCCCGAATTCAGGCTGCGCGGCGCAGCCGCACGAAGCCCCCTGAAC
CCTAGCCCCTGATCCCCGAC

Product: NusB antitermination factor

Products: NA

Alternate protein names: Protein nusB

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MAGSRKVAREFTLQGIYAWMIGGADVTLIAANLKEDEQFKRADEAYFRTLLYGVLKEEDMLSSRIAPLLDRAVAELSPIE
RSILLIGAYELLHCPDVPWRVAINESVELAKKFGGTDGHKYINGVLDKLAQDVRAVEIEHAKKRD

Sequences:

>Translated_145_residues
MAGSRKVAREFTLQGIYAWMIGGADVTLIAANLKEDEQFKRADEAYFRTLLYGVLKEEDMLSSRIAPLLDRAVAELSPIE
RSILLIGAYELLHCPDVPWRVAINESVELAKKFGGTDGHKYINGVLDKLAQDVRAVEIEHAKKRD
>Mature_144_residues
AGSRKVAREFTLQGIYAWMIGGADVTLIAANLKEDEQFKRADEAYFRTLLYGVLKEEDMLSSRIAPLLDRAVAELSPIER
SILLIGAYELLHCPDVPWRVAINESVELAKKFGGTDGHKYINGVLDKLAQDVRAVEIEHAKKRD

Specific function: Involved in the transcription termination process

COG id: COG0781

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nusB family

Homologues:

Organism=Escherichia coli, GI1786618, Length=125, Percent_Identity=40.8, Blast_Score=103, Evalue=6e-24,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NUSB_THIDA (Q3SGU8)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315950.1
- ProteinModelPortal:   Q3SGU8
- SMR:   Q3SGU8
- STRING:   Q3SGU8
- GeneID:   3671973
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2192
- NMPDR:   fig|292415.3.peg.2081
- eggNOG:   COG0781
- HOGENOM:   HBG734409
- OMA:   IPYKVVI
- PhylomeDB:   Q3SGU8
- BioCyc:   TDEN292415:TBD_2192-MONOMER
- HAMAP:   MF_00073
- InterPro:   IPR011605
- InterPro:   IPR006027
- Gene3D:   G3DSA:1.10.940.10
- TIGRFAMs:   TIGR01951

Pfam domain/function: PF01029 NusB; SSF48013 NusB_RsmB_TIM44

EC number: NA

Molecular weight: Translated: 16244; Mature: 16113

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSRKVAREFTLQGIYAWMIGGADVTLIAANLKEDEQFKRADEAYFRTLLYGVLKEEDM
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSSRIAPLLDRAVAELSPIERSILLIGAYELLHCPDVPWRVAINESVELAKKFGGTDGHK
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCHHH
YINGVLDKLAQDVRAVEIEHAKKRD
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGSRKVAREFTLQGIYAWMIGGADVTLIAANLKEDEQFKRADEAYFRTLLYGVLKEEDM
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSSRIAPLLDRAVAELSPIERSILLIGAYELLHCPDVPWRVAINESVELAKKFGGTDGHK
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHCCCCCHHH
YINGVLDKLAQDVRAVEIEHAKKRD
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA