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The map label for this gene is speE [H]

Identifier: 74318129

GI number: 74318129

Start: 2199736

End: 2200503

Strand: Reverse

Name: speE [H]

Synonym: Tbd_2111

Alternate gene names: 74318129

Gene position: 2200503-2199736 (Counterclockwise)

Preceding gene: 74318133

Following gene: 74318128

Centisome position: 75.62

GC content: 67.32

Gene sequence:

>768_bases
ATGGCAATGCGATTGCGGTTTGGGAGACGTCGGGCGGCCGACGACGGGCTGGAAGTTACCGAGGAGCGCGGCGTGCGCAC
GCTCCACCTCGGCAGCCAGGCGATCCAGAGCGCGATGCGGCTGAGCCGGCCGTGGGATCTCGAACTCGCCTACACGCGCG
CGATGATGGGTTTTCTGATGTTCAATCCCACGCCGCAGGCGGTTCTGATGGTCGGGCTGGGCGGCGGCTCGCTCGCCAAG
TTCATCCGCAAGCAGCGGCCGCAAACCCATATCACCGCGGTCGAGATCGATCCGCGGGTCATTGCCGCGGCGCGCGCGCA
TTTCGAGTTGCCGCCTAACGACGCAGCCCTCGAAGTGATCGAGGGCGACGGCGCGCTTTACGTGCGCCGGCACCCGGCGA
GCGCGGACGTCATCCTGCTCGACGGTTTCGACGCCGGCAACCAGGTCGAGGCGCTCGCGACGCAGACCTTCTACGCCGCC
TGCCACCGCGCCCTGAAGCCGGGCGGCGTGCTCGTCGTCAATCTGTGGGGGCGGGACCGGGACTACGCAGAATATTTCGC
GCGATTGACGCGTGCCTTCGATGGTGCGGTTGGCTGGATCTCGGTGCAGAACAAGACCAACGTCATCCTTTTCGCCTTCA
GCGAAGCGGACGCGCCCGCCCGCCTTGCCGCTGTCCTGCCGCGGCTCGCCGACCTGTCGAAGCGCTGGGGCATCGATCTG
CGCGCCTTCGCGCGCGATTTCCAGTGGGCAGACGATGCCTCCAGCTGA

Upstream 100 bases:

>100_bases
ACAGGAAAAACTGGGTGGTGCGCATGGTGGACAAGCCGGGAGGAAAAGCGGCATTTTAGCGTGCGGCCGTGTAATCTTCC
GCGCTCGATTCGAGGTGGAA

Downstream 100 bases:

>100_bases
GCGGGCGCGACTTCCCCTTCCGCCGGCTTGGGTTTCCCGCGCGGAAAGCGGCAGCCGGGAGGTCTGCGAAGTGCGCCGGT
TTCGTGCGTCGCGAGTCGCA

Product: spermidine synthase

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MAMRLRFGRRRAADDGLEVTEERGVRTLHLGSQAIQSAMRLSRPWDLELAYTRAMMGFLMFNPTPQAVLMVGLGGGSLAK
FIRKQRPQTHITAVEIDPRVIAAARAHFELPPNDAALEVIEGDGALYVRRHPASADVILLDGFDAGNQVEALATQTFYAA
CHRALKPGGVLVVNLWGRDRDYAEYFARLTRAFDGAVGWISVQNKTNVILFAFSEADAPARLAAVLPRLADLSKRWGIDL
RAFARDFQWADDASS

Sequences:

>Translated_255_residues
MAMRLRFGRRRAADDGLEVTEERGVRTLHLGSQAIQSAMRLSRPWDLELAYTRAMMGFLMFNPTPQAVLMVGLGGGSLAK
FIRKQRPQTHITAVEIDPRVIAAARAHFELPPNDAALEVIEGDGALYVRRHPASADVILLDGFDAGNQVEALATQTFYAA
CHRALKPGGVLVVNLWGRDRDYAEYFARLTRAFDGAVGWISVQNKTNVILFAFSEADAPARLAAVLPRLADLSKRWGIDL
RAFARDFQWADDASS
>Mature_254_residues
AMRLRFGRRRAADDGLEVTEERGVRTLHLGSQAIQSAMRLSRPWDLELAYTRAMMGFLMFNPTPQAVLMVGLGGGSLAKF
IRKQRPQTHITAVEIDPRVIAAARAHFELPPNDAALEVIEGDGALYVRRHPASADVILLDGFDAGNQVEALATQTFYAAC
HRALKPGGVLVVNLWGRDRDYAEYFARLTRAFDGAVGWISVQNKTNVILFAFSEADAPARLAAVLPRLADLSKRWGIDLR
AFARDFQWADDASS

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 28167; Mature: 28035

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMRLRFGRRRAADDGLEVTEERGVRTLHLGSQAIQSAMRLSRPWDLELAYTRAMMGFLM
CCEECCCCCCCCCCCCCHHHHHCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHE
FNPTPQAVLMVGLGGGSLAKFIRKQRPQTHITAVEIDPRVIAAARAHFELPPNDAALEVI
ECCCCCEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCEEEEHHHCCCCCCCCCEEEEE
EGDGALYVRRHPASADVILLDGFDAGNQVEALATQTFYAACHRALKPGGVLVVNLWGRDR
ECCCEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
DYAEYFARLTRAFDGAVGWISVQNKTNVILFAFSEADAPARLAAVLPRLADLSKRWGIDL
HHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCH
RAFARDFQWADDASS
HHHHHHCCCCCCCCC
>Mature Secondary Structure 
AMRLRFGRRRAADDGLEVTEERGVRTLHLGSQAIQSAMRLSRPWDLELAYTRAMMGFLM
CEECCCCCCCCCCCCCHHHHHCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHE
FNPTPQAVLMVGLGGGSLAKFIRKQRPQTHITAVEIDPRVIAAARAHFELPPNDAALEVI
ECCCCCEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCEEEEHHHCCCCCCCCCEEEEE
EGDGALYVRRHPASADVILLDGFDAGNQVEALATQTFYAACHRALKPGGVLVVNLWGRDR
ECCCEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
DYAEYFARLTRAFDGAVGWISVQNKTNVILFAFSEADAPARLAAVLPRLADLSKRWGIDL
HHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCH
RAFARDFQWADDASS
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]