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The map label for this gene is mrp [H]

Identifier: 74318126

GI number: 74318126

Start: 2197349

End: 2198437

Strand: Reverse

Name: mrp [H]

Synonym: Tbd_2108

Alternate gene names: 74318126

Gene position: 2198437-2197349 (Counterclockwise)

Preceding gene: 74318127

Following gene: 74318125

Centisome position: 75.55

GC content: 62.72

Gene sequence:

>1089_bases
ATGGCCGTTTCCGAACTTCAGGTGCAGTCCGCACTGAAAGAGTTGATCGATCCGAATACGCACAAGGACTATGTCACGAC
CAAATCCGCCCGCAACATCAAGATCGACGGCGACGCGGTGTCCGTCGACATCGCGCTTGGGTATCCTGCACAAAGCCAGC
TCGCCACGATCAAGCAGCAGGTCGAGGACAAGCTCAAGACCCTCGACGGCGTGAGCAAGGCGACGGCCAACGTCAGCTTC
AAGATCGTCTCCCACAGCGTCCAGCGCGGCGTCAAGCTGATCCCCAACGTCAAGAACATCATCGCGGTCGCGTCCGGCAA
GGGCGGGGTCGGCAAATCGACGACGGCCGTGAACCTCGCGCTCGCGCTTGCGGCCGAGGGCGCCCGCGTCGGCATGCTCG
ACGCCGACATCTACGGTCCCTCGCAACCGACGATGCTCGGCATCACCGACAAACCCGAGTCGACCGATGGCAAGAATCTT
GATCCCTTGATCGGCCACGGCATCCAGGCCATGTCGATTGGCTTCCTGATCGACGTCGAAACGCCGATGGTGTGGCGCGG
GCCGATGGTGACGCAGGCGCTCGAGCAGCTGCTCAACAACACCAACTGGAACGAGCTCGACTACCTCGTCGTCGACCTGC
CGCCGGGCACGGGCGACATCCAGTTGACGCTCGCGCAGCGCGTGCCCGTGACCGGCGCCGTGATCGTGACGACGCCGCAG
GACATCGCGCTGATCGACGCGCGCAAGGGGCTCAAGATGTTCGAGAAGGTCGGCATCCCGATCATCGGCGTCGTCGAGAA
CATGAGCCTGCACATCTGCTCGAACTGCGGGCACGAAGAGCGCATCTTCGGCGAAGGCGGCGGCGAACGCATGTGCCGCG
ACTACAACGTCGAGTTTCTCGGCGCGCTGCCGCTTGATTCCAGCATCCGTGCCGACACCGATTCCGGCAAGCCGTCAGTC
GTGTCCGACCCGGACGGGCGCGTGACCGAAATCTACAAGCAGATCGCGCGCCGCGTTGCTGTTAAGATTGGCGAGACGGC
CGTCGACCATTCGGCCAAATTCCCCAATATCGTCATTTCCAACACCTGA

Upstream 100 bases:

>100_bases
GCCAATGACAGGGAATCCCGCGTCCCTTCAGGGTTTTCGTTCACCCAAGGCGCGGGATTTCGTTAAAATGAGCGATTGCT
AATCAACCGCTGGAGCAAAC

Downstream 100 bases:

>100_bases
TGAGCATCAAGTCCGACCGATGGATCCGCCGCATGGCGGCCGAGCATGGCATGATCGAACCGTTCGAAGCCGGACAGATC
AAGCAGGCAGCGGGGCGATC

Product: chromosome partitioning ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MAVSELQVQSALKELIDPNTHKDYVTTKSARNIKIDGDAVSVDIALGYPAQSQLATIKQQVEDKLKTLDGVSKATANVSF
KIVSHSVQRGVKLIPNVKNIIAVASGKGGVGKSTTAVNLALALAAEGARVGMLDADIYGPSQPTMLGITDKPESTDGKNL
DPLIGHGIQAMSIGFLIDVETPMVWRGPMVTQALEQLLNNTNWNELDYLVVDLPPGTGDIQLTLAQRVPVTGAVIVTTPQ
DIALIDARKGLKMFEKVGIPIIGVVENMSLHICSNCGHEERIFGEGGGERMCRDYNVEFLGALPLDSSIRADTDSGKPSV
VSDPDGRVTEIYKQIARRVAVKIGETAVDHSAKFPNIVISNT

Sequences:

>Translated_362_residues
MAVSELQVQSALKELIDPNTHKDYVTTKSARNIKIDGDAVSVDIALGYPAQSQLATIKQQVEDKLKTLDGVSKATANVSF
KIVSHSVQRGVKLIPNVKNIIAVASGKGGVGKSTTAVNLALALAAEGARVGMLDADIYGPSQPTMLGITDKPESTDGKNL
DPLIGHGIQAMSIGFLIDVETPMVWRGPMVTQALEQLLNNTNWNELDYLVVDLPPGTGDIQLTLAQRVPVTGAVIVTTPQ
DIALIDARKGLKMFEKVGIPIIGVVENMSLHICSNCGHEERIFGEGGGERMCRDYNVEFLGALPLDSSIRADTDSGKPSV
VSDPDGRVTEIYKQIARRVAVKIGETAVDHSAKFPNIVISNT
>Mature_361_residues
AVSELQVQSALKELIDPNTHKDYVTTKSARNIKIDGDAVSVDIALGYPAQSQLATIKQQVEDKLKTLDGVSKATANVSFK
IVSHSVQRGVKLIPNVKNIIAVASGKGGVGKSTTAVNLALALAAEGARVGMLDADIYGPSQPTMLGITDKPESTDGKNLD
PLIGHGIQAMSIGFLIDVETPMVWRGPMVTQALEQLLNNTNWNELDYLVVDLPPGTGDIQLTLAQRVPVTGAVIVTTPQD
IALIDARKGLKMFEKVGIPIIGVVENMSLHICSNCGHEERIFGEGGGERMCRDYNVEFLGALPLDSSIRADTDSGKPSVV
SDPDGRVTEIYKQIARRVAVKIGETAVDHSAKFPNIVISNT

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=254, Percent_Identity=50.3937007874016, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI118572611, Length=272, Percent_Identity=40.8088235294118, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI6912540, Length=251, Percent_Identity=38.6454183266932, Blast_Score=172, Evalue=4e-43,
Organism=Escherichia coli, GI87082045, Length=337, Percent_Identity=51.3353115727003, Blast_Score=343, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI25143050, Length=256, Percent_Identity=39.84375, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6321347, Length=292, Percent_Identity=35.2739726027397, Blast_Score=175, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6322188, Length=274, Percent_Identity=33.9416058394161, Blast_Score=173, Evalue=4e-44,
Organism=Drosophila melanogaster, GI221511043, Length=255, Percent_Identity=42.3529411764706, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24667611, Length=256, Percent_Identity=40.625, Blast_Score=184, Evalue=9e-47,
Organism=Drosophila melanogaster, GI19921440, Length=239, Percent_Identity=39.3305439330544, Blast_Score=151, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 38629; Mature: 38498

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSELQVQSALKELIDPNTHKDYVTTKSARNIKIDGDAVSVDIALGYPAQSQLATIKQQ
CCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCEEEEEEEECCCCHHHHHHHHHH
VEDKLKTLDGVSKATANVSFKIVSHSVQRGVKLIPNVKNIIAVASGKGGVGKSTTAVNLA
HHHHHHHHHCHHHHHCCEEEEEEHHHHHCCHHHCCCCCCEEEEECCCCCCCCCCHHEEEE
LALAAEGARVGMLDADIYGPSQPTMLGITDKPESTDGKNLDPLIGHGIQAMSIGFLIDVE
EEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCEEEEEEEEEECC
TPMVWRGPMVTQALEQLLNNTNWNELDYLVVDLPPGTGDIQLTLAQRVPVTGAVIVTTPQ
CCCEECCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEEEEECCC
DIALIDARKGLKMFEKVGIPIIGVVENMSLHICSNCGHEERIFGEGGGERMCRDYNVEFL
CEEEEECHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCEEECCCCCCCHHHCCCEEEE
GALPLDSSIRADTDSGKPSVVSDPDGRVTEIYKQIARRVAVKIGETAVDHSAKFPNIVIS
EECCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEE
NT
CC
>Mature Secondary Structure 
AVSELQVQSALKELIDPNTHKDYVTTKSARNIKIDGDAVSVDIALGYPAQSQLATIKQQ
CHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCEEEEEEEECCCCHHHHHHHHHH
VEDKLKTLDGVSKATANVSFKIVSHSVQRGVKLIPNVKNIIAVASGKGGVGKSTTAVNLA
HHHHHHHHHCHHHHHCCEEEEEEHHHHHCCHHHCCCCCCEEEEECCCCCCCCCCHHEEEE
LALAAEGARVGMLDADIYGPSQPTMLGITDKPESTDGKNLDPLIGHGIQAMSIGFLIDVE
EEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCEEEEEEEEEECC
TPMVWRGPMVTQALEQLLNNTNWNELDYLVVDLPPGTGDIQLTLAQRVPVTGAVIVTTPQ
CCCEECCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEEEEECCC
DIALIDARKGLKMFEKVGIPIIGVVENMSLHICSNCGHEERIFGEGGGERMCRDYNVEFL
CEEEEECHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCEEECCCCCCCHHHCCCEEEE
GALPLDSSIRADTDSGKPSVVSDPDGRVTEIYKQIARRVAVKIGETAVDHSAKFPNIVIS
EECCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEE
NT
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]