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The map label for this gene is panD

Identifier: 74318073

GI number: 74318073

Start: 2142261

End: 2142641

Strand: Direct

Name: panD

Synonym: Tbd_2055

Alternate gene names: 74318073

Gene position: 2142261-2142641 (Clockwise)

Preceding gene: 74318072

Following gene: 74318082

Centisome position: 73.62

GC content: 63.52

Gene sequence:

>381_bases
ATGCAAAGAACGATGCTCAAGTCCAAGCTGCATCGCGCGACCGTCACGCATTCCGAGCTGCATTACGAAGGCTCGTGCGC
CATCGACGAGTCGCTGCTCGAAGCGGCCAATATCCACGAGTACGAGCAGATCCAGATCTACAACGTCAGCAACGGCGAGC
GCTTCACCACCTATGCCATCCGCGCGGCGCGCGGGTCGGGCGTCATCTCGGTGAACGGCGCCGCGGCGCACAAGGCGAAT
CCCGGCGACCTCGTCATCATCGCCACCTATGCGACGTACAACGAACTCGAGATGGCGCGCTACGCGCCCGAACTCGTCTA
CGTCGACGCCGCCAACGCCATCGTCGACACGCGCCAGACGATCCCGGTCCAGGCTGCCTAG

Upstream 100 bases:

>100_bases
CAGCCGGCATCGCCGCCTGAGCGTCACAGGCGCCGCCCTTTGGCCCCTTCCCCCCGAAGGGTATAATGTCGCTCCTTTTT
GTGATTGTGAGGGCACCGTC

Downstream 100 bases:

>100_bases
GACTTATACGGCGGTGCCGGCGCTCGCGTGCCGCCCTTCCGCCGCGAACGGCTTCAGCTTCCAGATATCCGCGTTGTATT
CCTGCATCGTGCGGTCGGTC

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MQRTMLKSKLHRATVTHSELHYEGSCAIDESLLEAANIHEYEQIQIYNVSNGERFTTYAIRAARGSGVISVNGAAAHKAN
PGDLVIIATYATYNELEMARYAPELVYVDAANAIVDTRQTIPVQAA

Sequences:

>Translated_126_residues
MQRTMLKSKLHRATVTHSELHYEGSCAIDESLLEAANIHEYEQIQIYNVSNGERFTTYAIRAARGSGVISVNGAAAHKAN
PGDLVIIATYATYNELEMARYAPELVYVDAANAIVDTRQTIPVQAA
>Mature_126_residues
MQRTMLKSKLHRATVTHSELHYEGSCAIDESLLEAANIHEYEQIQIYNVSNGERFTTYAIRAARGSGVISVNGAAAHKAN
PGDLVIIATYATYNELEMARYAPELVYVDAANAIVDTRQTIPVQAA

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=126, Percent_Identity=56.3492063492063, Blast_Score=147, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_THIDA (Q3SH81)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_315813.1
- ProteinModelPortal:   Q3SH81
- SMR:   Q3SH81
- STRING:   Q3SH81
- GeneID:   3672226
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2055
- NMPDR:   fig|292415.3.peg.2195
- eggNOG:   COG0853
- HOGENOM:   HBG302821
- OMA:   LYSKIHR
- PhylomeDB:   Q3SH81
- ProtClustDB:   PRK05449
- BioCyc:   TDEN292415:TBD_2055-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 13826; Mature: 13826

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRTMLKSKLHRATVTHSELHYEGSCAIDESLLEAANIHEYEQIQIYNVSNGERFTTYAI
CCCHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHCCCCCCEEEEEEECCCCCEEEEEEE
RAARGSGVISVNGAAAHKANPGDLVIIATYATYNELEMARYAPELVYVDAANAIVDTRQT
EECCCCCEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCEEEEEECCCCEECCCCC
IPVQAA
CEEECC
>Mature Secondary Structure
MQRTMLKSKLHRATVTHSELHYEGSCAIDESLLEAANIHEYEQIQIYNVSNGERFTTYAI
CCCHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHCCCCCCEEEEEEECCCCCEEEEEEE
RAARGSGVISVNGAAAHKANPGDLVIIATYATYNELEMARYAPELVYVDAANAIVDTRQT
EECCCCCEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCEEEEEECCCCEECCCCC
IPVQAA
CEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA