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The map label for this gene is wrbA [H]

Identifier: 74317997

GI number: 74317997

Start: 2071834

End: 2072427

Strand: Direct

Name: wrbA [H]

Synonym: Tbd_1979

Alternate gene names: 74317997

Gene position: 2071834-2072427 (Clockwise)

Preceding gene: 74317996

Following gene: 74317998

Centisome position: 71.2

GC content: 72.05

Gene sequence:

>594_bases
ATGACGGAAATTCTTGTGCTGTATTACAGCGTCGGCGGCAGCGTGCGCGAGATGGCGCACCTGGTCGCCCGCGGCGTCAA
CCACGTCGAGGGCGCGAGTGCGCGGCTGCGCACCGTGCCGCCCGTCGCGCCGCGCACCGAGGTCGCCGAGCCGCCGGTGC
CGGACGAGGGCGCCCCCTACGCCGAACTCGCCGACCTCGAACAATGCGCCGGGCTCGCGCTCGGCTCGCCGACCCGCTTC
GGCAACATGGCGGCCGCGCCGAAATATTTCCTCGACTCGACCGGCGCGCTGTGGGCCAAAGGCGCGCTCGTCGGCAAGCC
CGCGGCGGTCTTCACCTCGACCGCGAGCCTGCACGGCGGCCAGGAGACGACGCTGACGAGCATGATGCTGCCGCTGCTGC
ACCACGGCATGCTGGTCCTCGGGCTGCCCTACACGCTGCCCGAGGTGAACACGACCGCGAGCGGCGGCACCCCCTACGGC
CCGAGCCACTGGGCCGGCGCCGGCGACGACAAACCGCTGACCGACGACGAACGCGCGCTGTGCATCGCGCTCGGCAAACG
GCTCGCCGAAACGGCGGTCAAGCTGGCGGCGTGA

Upstream 100 bases:

>100_bases
GGGACGAGGCGCGCCGCTACACGCTCACCTTCGGCCGGCTGCTCGAGCAGACCCCGAGTTTCGACCTGGTCGATTTCACC
CTATTCGAAGAGGCCCAGCC

Downstream 100 bases:

>100_bases
GCGCCTTCGCGCTCACCCGAGAAAAACCGATCTTTGATGAAGTCAGGCCGAGGCCGAACGATGAAATTCCTGCAGTACGT
CGCGAGCGCGAGCCTGATCG

Product: tryptophan repressor binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTEILVLYYSVGGSVREMAHLVARGVNHVEGASARLRTVPPVAPRTEVAEPPVPDEGAPYAELADLEQCAGLALGSPTRF
GNMAAAPKYFLDSTGALWAKGALVGKPAAVFTSTASLHGGQETTLTSMMLPLLHHGMLVLGLPYTLPEVNTTASGGTPYG
PSHWAGAGDDKPLTDDERALCIALGKRLAETAVKLAA

Sequences:

>Translated_197_residues
MTEILVLYYSVGGSVREMAHLVARGVNHVEGASARLRTVPPVAPRTEVAEPPVPDEGAPYAELADLEQCAGLALGSPTRF
GNMAAAPKYFLDSTGALWAKGALVGKPAAVFTSTASLHGGQETTLTSMMLPLLHHGMLVLGLPYTLPEVNTTASGGTPYG
PSHWAGAGDDKPLTDDERALCIALGKRLAETAVKLAA
>Mature_196_residues
TEILVLYYSVGGSVREMAHLVARGVNHVEGASARLRTVPPVAPRTEVAEPPVPDEGAPYAELADLEQCAGLALGSPTRFG
NMAAAPKYFLDSTGALWAKGALVGKPAAVFTSTASLHGGQETTLTSMMLPLLHHGMLVLGLPYTLPEVNTTASGGTPYGP
SHWAGAGDDKPLTDDERALCIALGKRLAETAVKLAA

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=197, Percent_Identity=39.5939086294416, Blast_Score=132, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6319849, Length=205, Percent_Identity=35.1219512195122, Blast_Score=101, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6320235, Length=199, Percent_Identity=31.1557788944724, Blast_Score=85, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6319526, Length=160, Percent_Identity=34.375, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: NA

Molecular weight: Translated: 20444; Mature: 20312

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEILVLYYSVGGSVREMAHLVARGVNHVEGASARLRTVPPVAPRTEVAEPPVPDEGAPY
CCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCH
AELADLEQCAGLALGSPTRFGNMAAAPKYFLDSTGALWAKGALVGKPAAVFTSTASLHGG
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCHHHCCCCCCCCHHHHCCHHHCCCC
QETTLTSMMLPLLHHGMLVLGLPYTLPEVNTTASGGTPYGPSHWAGAGDDKPLTDDERAL
CHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
CIALGKRLAETAVKLAA
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEILVLYYSVGGSVREMAHLVARGVNHVEGASARLRTVPPVAPRTEVAEPPVPDEGAPY
CEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCH
AELADLEQCAGLALGSPTRFGNMAAAPKYFLDSTGALWAKGALVGKPAAVFTSTASLHGG
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCHHHCCCCCCCCHHHHCCHHHCCCC
QETTLTSMMLPLLHHGMLVLGLPYTLPEVNTTASGGTPYGPSHWAGAGDDKPLTDDERAL
CHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
CIALGKRLAETAVKLAA
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA