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The map label for this gene is hmp [C]

Identifier: 74317966

GI number: 74317966

Start: 2042950

End: 2043615

Strand: Reverse

Name: hmp [C]

Synonym: Tbd_1948

Alternate gene names: 74317966

Gene position: 2043615-2042950 (Counterclockwise)

Preceding gene: 74317968

Following gene: 74317962

Centisome position: 70.23

GC content: 65.02

Gene sequence:

>666_bases
ATGGACCACGCCGTCAAGCTTCTCATGACCCAGTTCGTCACCCATGACGTGAAGCGCTTCATCGTCAGCAAGCCGCCGGG
GTTTTCCGTCATGCCGGGCCAGGGCGTCGAACTCGCGATCGATCGACCCGGCCTGCGCGAGCAGCGCCGGCCTTTCACGC
CGACCGGGCTCGCGGCGGACGCGGTGCTCGAATTCACGATCAAGGGCTACCCAAGCCACGCCGGCGTGACCGACGCGCTG
CACCGGCTGGAACCCGGTGCGGAAATGCTGATGTCGGAGCCTTTCGGCACGATCCAGTACAAGGGGCCGGGCGTGTTCGT
CGCGGGCGGCGCCGGCATTACGCCTTTTCTCGCGATCCTGCGCGAACGTGCGCACCGGGGCGAGCTCGCCGGTCAGACCC
TGATCTTCTCGAACAAGACGCCGGGCGACGTGATCTGCGAAAAGGAATTGCGGCATCTGCTAGGCGAGCGCTGCCTCCTG
CTGACGACCGCGGCGGATGCACCGGGGTACGCGCATCGGCGCATCGATCGCGCTTTTCTCGAAGAAACGATTGACGACTT
CACGCAGAATTTCTATGTCTGCGGACCGCCGCCTTTCATGGAAGCCGTCAACGGCGCGCTGACCGATCTCGGCGCGCGGG
CGGAGAGCCTGGTGTTCGAACAGTAA

Upstream 100 bases:

>100_bases
CAACCCATTCCCGCGTAGGAATCCTGGCGATGTCCCGCCGGGGCCGTCCGGGGGGCGGGCCCATGTCTAAGCTGAAAGCA
TCCCCATCCGGAGCCGAACC

Downstream 100 bases:

>100_bases
TGCCTCGGCGGACCCGGAACGAATCCCGGGTTCGCGAGGGGGCCGAGCGTCGTCGGCCAGAGGAAGGGAGGGCGGCCCGG
CCGCGGAAGGGCCGGGAACG

Product: putative flavodoxin reductase

Products: @TETR01txt*tetrahydropteridine!; NO3-; NAD(P); Proton [C]

Alternate protein names: Oxidoreductase; CDP-6-Deoxy-Delta-3 4-Glucoseen Reductase; Ferredoxin; Flavodoxin Reductase Family; Oxidoreductase FAD/NAD

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MDHAVKLLMTQFVTHDVKRFIVSKPPGFSVMPGQGVELAIDRPGLREQRRPFTPTGLAADAVLEFTIKGYPSHAGVTDAL
HRLEPGAEMLMSEPFGTIQYKGPGVFVAGGAGITPFLAILRERAHRGELAGQTLIFSNKTPGDVICEKELRHLLGERCLL
LTTAADAPGYAHRRIDRAFLEETIDDFTQNFYVCGPPPFMEAVNGALTDLGARAESLVFEQ

Sequences:

>Translated_221_residues
MDHAVKLLMTQFVTHDVKRFIVSKPPGFSVMPGQGVELAIDRPGLREQRRPFTPTGLAADAVLEFTIKGYPSHAGVTDAL
HRLEPGAEMLMSEPFGTIQYKGPGVFVAGGAGITPFLAILRERAHRGELAGQTLIFSNKTPGDVICEKELRHLLGERCLL
LTTAADAPGYAHRRIDRAFLEETIDDFTQNFYVCGPPPFMEAVNGALTDLGARAESLVFEQ
>Mature_221_residues
MDHAVKLLMTQFVTHDVKRFIVSKPPGFSVMPGQGVELAIDRPGLREQRRPFTPTGLAADAVLEFTIKGYPSHAGVTDAL
HRLEPGAEMLMSEPFGTIQYKGPGVFVAGGAGITPFLAILRERAHRGELAGQTLIFSNKTPGDVICEKELRHLLGERCLL
LTTAADAPGYAHRRIDRAFLEETIDDFTQNFYVCGPPPFMEAVNGALTDLGARAESLVFEQ

Specific function: Possesses Dihydropteridine Reductase Activity. Also Has Nitric Oxide Dioxygenase Activity. Seems To Reduces The Complexed Fe(3+) Iron Of Siderophores To Fe(2+), Thus Releasing It From The Chelator. [C]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.5.1.34 [C]

Molecular weight: Translated: 24133; Mature: 24133

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHAVKLLMTQFVTHDVKRFIVSKPPGFSVMPGQGVELAIDRPGLREQRRPFTPTGLAAD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCCCCHHHH
AVLEFTIKGYPSHAGVTDALHRLEPGAEMLMSEPFGTIQYKGPGVFVAGGAGITPFLAIL
HHHEEEECCCCCCCCHHHHHHHCCCCHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHHH
RERAHRGELAGQTLIFSNKTPGDVICEKELRHLLGERCLLLTTAADAPGYAHRRIDRAFL
HHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHH
EETIDDFTQNFYVCGPPPFMEAVNGALTDLGARAESLVFEQ
HHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDHAVKLLMTQFVTHDVKRFIVSKPPGFSVMPGQGVELAIDRPGLREQRRPFTPTGLAAD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCCCCHHHH
AVLEFTIKGYPSHAGVTDALHRLEPGAEMLMSEPFGTIQYKGPGVFVAGGAGITPFLAIL
HHHEEEECCCCCCCCHHHHHHHCCCCHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHHH
RERAHRGELAGQTLIFSNKTPGDVICEKELRHLLGERCLLLTTAADAPGYAHRRIDRAFL
HHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHH
EETIDDFTQNFYVCGPPPFMEAVNGALTDLGARAESLVFEQ
HHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dihydropteridine; 2 nitric oxide; O2; NAD(P)H [C]

Specific reaction: NAD(P)H + dihydropteridine = NAD(P)+ @TETR01.txt*tetrahydropteridine! 2 nitric oxide + 2 O2 + NAD(P)H = 2 NO3- + NAD(P) + Proton [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA