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The map label for this gene is mlaC [H]

Identifier: 74317914

GI number: 74317914

Start: 1993586

End: 1994221

Strand: Reverse

Name: mlaC [H]

Synonym: Tbd_1896

Alternate gene names: 74317914

Gene position: 1994221-1993586 (Counterclockwise)

Preceding gene: 74317915

Following gene: 74317913

Centisome position: 68.53

GC content: 65.72

Gene sequence:

>636_bases
ATGTTGCGCACGTTTTTGCTGCCGCTGGCGCTGATCGCCGGACTGTTCTCCACGCCGGTGACGGCGGCCGACACGCCGCC
CGACGTTCTCGCCCGGACGACGACCCAGGAGGTCCTCGCCATCCTCAAGCAGGACCAGGAAATCCGGAGCGGCAACCTCA
ACAAGGTGTATCAGCTCGTCGAGGCCAAGATCCTGCCAAACTTCGATTTCAACCGCATGACGCAGCTTGCCGTCGGCAAG
CACTGGCCGCGCGCGAGCCCGAAGCAGAAGCAGGCGCTCGTGACCGAGTTCCGCAACCTTCTGGTGCGCACCTACTCGAG
CTCGCTGACCGCGTTCACCAACCAGACCGTCGATTTCAAGCCCATGACGCTGAAGCCCGACGACACCGACGTGACCGTCC
GCAGCGAGATCCGCCAGCCCGGCGGGCAGCCGATCCCGATCGACTACGCGATGTACAAGACGGCTTTCGGCTGGAAGGTC
TACGACGTCTCGATCGACGGCGTGAGCCTCGTCACCAACTACCGCGCCTCGTTCGCGAGCACGATACGCCAGAGCGGCAT
CGACGGCCTGGTCAAGACGCTGGCCGACAAGTCGGCGAGCGCCGCGGCCAAGCCGGCGGCACGCCCGGCGCCGTGA

Upstream 100 bases:

>100_bases
GCAGCTTGCCCGGCTGACCGGTGAACTCCGCTAAGGGGGAAGGCGTCTACTCCCTGCCTGCCCGAATCGGGCCCCCGTTC
TCTACACATAGGAAACCGTT

Downstream 100 bases:

>100_bases
TCGCCTGCGACGGCGAGCGCTGCCGGCTCGGCGGCGCGGTGACGGTCGACAGCGTCGGCGGCCTGTTGCGCGAACTCGAA
CCCCATTTGCGGGGCGGCGT

Product: putative signal peptide protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MLRTFLLPLALIAGLFSTPVTAADTPPDVLARTTTQEVLAILKQDQEIRSGNLNKVYQLVEAKILPNFDFNRMTQLAVGK
HWPRASPKQKQALVTEFRNLLVRTYSSSLTAFTNQTVDFKPMTLKPDDTDVTVRSEIRQPGGQPIPIDYAMYKTAFGWKV
YDVSIDGVSLVTNYRASFASTIRQSGIDGLVKTLADKSASAAAKPAARPAP

Sequences:

>Translated_211_residues
MLRTFLLPLALIAGLFSTPVTAADTPPDVLARTTTQEVLAILKQDQEIRSGNLNKVYQLVEAKILPNFDFNRMTQLAVGK
HWPRASPKQKQALVTEFRNLLVRTYSSSLTAFTNQTVDFKPMTLKPDDTDVTVRSEIRQPGGQPIPIDYAMYKTAFGWKV
YDVSIDGVSLVTNYRASFASTIRQSGIDGLVKTLADKSASAAAKPAARPAP
>Mature_211_residues
MLRTFLLPLALIAGLFSTPVTAADTPPDVLARTTTQEVLAILKQDQEIRSGNLNKVYQLVEAKILPNFDFNRMTQLAVGK
HWPRASPKQKQALVTEFRNLLVRTYSSSLTAFTNQTVDFKPMTLKPDDTDVTVRSEIRQPGGQPIPIDYAMYKTAFGWKV
YDVSIDGVSLVTNYRASFASTIRQSGIDGLVKTLADKSASAAAKPAARPAP

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=196, Percent_Identity=29.5918367346939, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 23187; Mature: 23187

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTFLLPLALIAGLFSTPVTAADTPPDVLARTTTQEVLAILKQDQEIRSGNLNKVYQLV
CHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHH
EAKILPNFDFNRMTQLAVGKHWPRASPKQKQALVTEFRNLLVRTYSSSLTAFTNQTVDFK
HHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PMTLKPDDTDVTVRSEIRQPGGQPIPIDYAMYKTAFGWKVYDVSIDGVSLVTNYRASFAS
CEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEEEEECCHHHHHHHHHHHHH
TIRQSGIDGLVKTLADKSASAAAKPAARPAP
HHHHHCHHHHHHHHHHCCHHHHCCCCCCCCC
>Mature Secondary Structure
MLRTFLLPLALIAGLFSTPVTAADTPPDVLARTTTQEVLAILKQDQEIRSGNLNKVYQLV
CHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHH
EAKILPNFDFNRMTQLAVGKHWPRASPKQKQALVTEFRNLLVRTYSSSLTAFTNQTVDFK
HHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PMTLKPDDTDVTVRSEIRQPGGQPIPIDYAMYKTAFGWKVYDVSIDGVSLVTNYRASFAS
CEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEEEEECCHHHHHHHHHHHHH
TIRQSGIDGLVKTLADKSASAAAKPAARPAP
HHHHHCHHHHHHHHHHCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]