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The map label for this gene is ymfI [H]

Identifier: 74317904

GI number: 74317904

Start: 1985170

End: 1985898

Strand: Reverse

Name: ymfI [H]

Synonym: Tbd_1886

Alternate gene names: 74317904

Gene position: 1985898-1985170 (Counterclockwise)

Preceding gene: 74317905

Following gene: 74317903

Centisome position: 68.25

GC content: 55.69

Gene sequence:

>729_bases
TTGACTCCGGCCATGGATAAGCCGCGCAAAACGATCTTGCTATTTGGTGCTAGTGGCGCAATCGGATCCTCCATTGCGGA
CTTATTCTTGTCTCGCGACTGGAGCGTAGTCGGCGTGACCCGCAGTGTGCGCTCCGGTCAAGCCAATGGAGTGTCCTGGA
TAATCGCTGATCCGTTGGCCGGTCACGTGGCAGCGGACGGTTATGATGAATACGCTCCATACCATGCCGTGTGCTGGGCC
CAGGGAGGAAACGTCAACGATAGCGTCTATGACGTAGATGTGGATGCGCATTTACAGCTCTATCAGACCAACTGCATATA
CATCCTGTCGTCGTTGAAGCTGCTTCTGCAGCGGAGCTTGCTCGCCCAGCCTGCGAGGTTATGCGTCATCAGTTCGATCT
GGCAGGAGATTGCGAGGCAAAACAAGCTCTCCTATGGCATGACGAAATCGGCACTGCGAGGGCTGGTGTTGTCGGCGGCG
GCGGACCTCGCGGCTGACGGCCATCTTGTTAACGCCATACTTCCGGGGGCGCTGGACACGCCAATGACTCGCGAAAATCT
TACCGCTGAACAGATAGGCGAATTGGCTAGCGCAACACAATTCGGTCGTCTTCCGCAGTTGGGAGATGTTTCCCGGCTCG
CGATGTTTCTTTGCTCGGAAGAGAATACGGGCATAACTGGCCAGTTCATAGCCGCTGACTTGGGATTTAGCCGTGTCCGT
ATCCTTTGA

Upstream 100 bases:

>100_bases
AAGAGGATGCTAAGCGCATAGAAATGCTTGAGAGACGATGGCACGTGCTTTCGGCCGATGAGAAGGCGAGCACGTCGACG
TATGTAAACCAACCGAACAT

Downstream 100 bases:

>100_bases
TATCCATTCAGAAATCAAGCCCTATCAAGTTCGGATCGGAAAAGATTTGCTTGAGGCGACGTTCGAGGCCGCGAACGACA
GCATTTTCCTCTGCGATCGT

Product: oxo-acyl acyl carrier protein dehydrogenase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTPAMDKPRKTILLFGASGAIGSSIADLFLSRDWSVVGVTRSVRSGQANGVSWIIADPLAGHVAADGYDEYAPYHAVCWA
QGGNVNDSVYDVDVDAHLQLYQTNCIYILSSLKLLLQRSLLAQPARLCVISSIWQEIARQNKLSYGMTKSALRGLVLSAA
ADLAADGHLVNAILPGALDTPMTRENLTAEQIGELASATQFGRLPQLGDVSRLAMFLCSEENTGITGQFIAADLGFSRVR
IL

Sequences:

>Translated_242_residues
MTPAMDKPRKTILLFGASGAIGSSIADLFLSRDWSVVGVTRSVRSGQANGVSWIIADPLAGHVAADGYDEYAPYHAVCWA
QGGNVNDSVYDVDVDAHLQLYQTNCIYILSSLKLLLQRSLLAQPARLCVISSIWQEIARQNKLSYGMTKSALRGLVLSAA
ADLAADGHLVNAILPGALDTPMTRENLTAEQIGELASATQFGRLPQLGDVSRLAMFLCSEENTGITGQFIAADLGFSRVR
IL
>Mature_241_residues
TPAMDKPRKTILLFGASGAIGSSIADLFLSRDWSVVGVTRSVRSGQANGVSWIIADPLAGHVAADGYDEYAPYHAVCWAQ
GGNVNDSVYDVDVDAHLQLYQTNCIYILSSLKLLLQRSLLAQPARLCVISSIWQEIARQNKLSYGMTKSALRGLVLSAAA
DLAADGHLVNAILPGALDTPMTRENLTAEQIGELASATQFGRLPQLGDVSRLAMFLCSEENTGITGQFIAADLGFSRVRI
L

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 25940; Mature: 25809

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAMDKPRKTILLFGASGAIGSSIADLFLSRDWSVVGVTRSVRSGQANGVSWIIADPLA
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCEEEEEECCCC
GHVAADGYDEYAPYHAVCWAQGGNVNDSVYDVDVDAHLQLYQTNCIYILSSLKLLLQRSL
CCCCCCCCHHCCCCEEEEEECCCCCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHH
LAQPARLCVISSIWQEIARQNKLSYGMTKSALRGLVLSAAADLAADGHLVNAILPGALDT
HHCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
PMTRENLTAEQIGELASATQFGRLPQLGDVSRLAMFLCSEENTGITGQFIAADLGFSRVR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHEEECCCCCEEE
IL
EC
>Mature Secondary Structure 
TPAMDKPRKTILLFGASGAIGSSIADLFLSRDWSVVGVTRSVRSGQANGVSWIIADPLA
CCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCEEEEEECCCC
GHVAADGYDEYAPYHAVCWAQGGNVNDSVYDVDVDAHLQLYQTNCIYILSSLKLLLQRSL
CCCCCCCCHHCCCCEEEEEECCCCCCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHH
LAQPARLCVISSIWQEIARQNKLSYGMTKSALRGLVLSAAADLAADGHLVNAILPGALDT
HHCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
PMTRENLTAEQIGELASATQFGRLPQLGDVSRLAMFLCSEENTGITGQFIAADLGFSRVR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHEEECCCCCEEE
IL
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]