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The map label for this gene is tagO [H]

Identifier: 74317890

GI number: 74317890

Start: 1968924

End: 1969886

Strand: Reverse

Name: tagO [H]

Synonym: Tbd_1872

Alternate gene names: 74317890

Gene position: 1969886-1968924 (Counterclockwise)

Preceding gene: 74317891

Following gene: 74317889

Centisome position: 67.7

GC content: 65.73

Gene sequence:

>963_bases
ATGATGGGCATGCTCGCTGTCCTTGCGGCCTTTGCCGCGAGCTGGCTTACGCTCGGGGGGCTACTGAAGCGCCGTCATGT
CCTGCCCATGGATCACCCCAATGCACGCTCGCTACACGCGACCCCGACCCCGCGGATCGGTGGACTCGGCATCATGGCAG
GGGTAATAGTCGCGGGCCTGTGGCTTGCCGACGCGGCTTTGCTTCCGATACTTCTCGGGGCCACGGCATTGGCCGGGCTG
TCGCTCGCGGACGATGTACGCGGGCTACCCGTGTACGTACGTTTCCTGGCGCACTTCGTTGCCGCGGCGGCTTGCCTGCT
GACTCTGGGTTTGTCCGGATGGAGTTTGCTCGCGGGTACGCTCGCAGTCGTGTGGATGACCAATCTTTACAATTTCATGG
ACGGCGCCGATGGACTGGCCGGGGGCATGGCCGTCATTGGCTTCGGTGCGCTCGCCCTGGCGGCGTGGCTCGGCGACGCG
CCCGTACTGGCTGCGTTCTGTGCCGCGCCGGCTGCCGCGGCCTTGGCCTTCCTGCGCTTCAATTTTCCGCCGGCACGGCT
CTTCATGGGCGACGCCGGGTCGATCCCGCTCGGTTTCATGGCGGCCACACTCGGGATACTCGGCGCGCGGCAGGGGGTAT
GGCCGTGGGCGTTTCCGCTGATCGTGTTCTCGCCCTTCATCGTCGACGCGACCGCGACGCTCGCCCGGCGAGCGTCGCGA
GGCGAAAAGGTCTGGCGCGCGCATCGTTCCCACTATTACCAGCGCGTGGTGTTGCTCGGCGCGTCGCATCGCCAGCTCGC
CGTGGCGGCGTGGGGCCTGATGCTCGCGATGGCCGCGCTGGGATTTTTGCTGCGGTCGTTTCCGCAACAGGCGACCGCGC
TGCTTATACTGTCGGCCGCAATCTACCTGCTGATTTTTTTTGCCATCGACCGGCGCTGGCGTCTGGCCCGTAATGAAGTT
TAA

Upstream 100 bases:

>100_bases
TGACCGGCTCGCTTTGGGTAGATGCCTCGCTGATCCGGGAGCGCCTCGGTTGGACGCCGCCGTATTCGATGGCGGACGGG
CTGGCCGCGACGGTCGCCCG

Downstream 100 bases:

>100_bases
TTCGCGCACCCTCGTCATCATCGTCTACGACATCCTGGTGGCGGCGTTCGCCTGGCTTGGCGCCTACTGGCTGCGCTTCA
ATCTCGACGTGCCGCCGGAG

Product: putative undecaprenyl phosphate N-acetylglucosaminyltransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MMGMLAVLAAFAASWLTLGGLLKRRHVLPMDHPNARSLHATPTPRIGGLGIMAGVIVAGLWLADAALLPILLGATALAGL
SLADDVRGLPVYVRFLAHFVAAAACLLTLGLSGWSLLAGTLAVVWMTNLYNFMDGADGLAGGMAVIGFGALALAAWLGDA
PVLAAFCAAPAAAALAFLRFNFPPARLFMGDAGSIPLGFMAATLGILGARQGVWPWAFPLIVFSPFIVDATATLARRASR
GEKVWRAHRSHYYQRVVLLGASHRQLAVAAWGLMLAMAALGFLLRSFPQQATALLILSAAIYLLIFFAIDRRWRLARNEV

Sequences:

>Translated_320_residues
MMGMLAVLAAFAASWLTLGGLLKRRHVLPMDHPNARSLHATPTPRIGGLGIMAGVIVAGLWLADAALLPILLGATALAGL
SLADDVRGLPVYVRFLAHFVAAAACLLTLGLSGWSLLAGTLAVVWMTNLYNFMDGADGLAGGMAVIGFGALALAAWLGDA
PVLAAFCAAPAAAALAFLRFNFPPARLFMGDAGSIPLGFMAATLGILGARQGVWPWAFPLIVFSPFIVDATATLARRASR
GEKVWRAHRSHYYQRVVLLGASHRQLAVAAWGLMLAMAALGFLLRSFPQQATALLILSAAIYLLIFFAIDRRWRLARNEV
>Mature_320_residues
MMGMLAVLAAFAASWLTLGGLLKRRHVLPMDHPNARSLHATPTPRIGGLGIMAGVIVAGLWLADAALLPILLGATALAGL
SLADDVRGLPVYVRFLAHFVAAAACLLTLGLSGWSLLAGTLAVVWMTNLYNFMDGADGLAGGMAVIGFGALALAAWLGDA
PVLAAFCAAPAAAALAFLRFNFPPARLFMGDAGSIPLGFMAATLGILGARQGVWPWAFPLIVFSPFIVDATATLARRASR
GEKVWRAHRSHYYQRVVLLGASHRQLAVAAWGLMLAMAALGFLLRSFPQQATALLILSAAIYLLIFFAIDRRWRLARNEV

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=270, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 33852; Mature: 33852

Theoretical pI: Translated: 11.42; Mature: 11.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGMLAVLAAFAASWLTLGGLLKRRHVLPMDHPNARSLHATPTPRIGGLGIMAGVIVAGL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
WLADAALLPILLGATALAGLSLADDVRGLPVYVRFLAHFVAAAACLLTLGLSGWSLLAGT
HHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LAVVWMTNLYNFMDGADGLAGGMAVIGFGALALAAWLGDAPVLAAFCAAPAAAALAFLRF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
NFPPARLFMGDAGSIPLGFMAATLGILGARQGVWPWAFPLIVFSPFIVDATATLARRASR
CCCHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GEKVWRAHRSHYYQRVVLLGASHRQLAVAAWGLMLAMAALGFLLRSFPQQATALLILSAA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYLLIFFAIDRRWRLARNEV
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMGMLAVLAAFAASWLTLGGLLKRRHVLPMDHPNARSLHATPTPRIGGLGIMAGVIVAGL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
WLADAALLPILLGATALAGLSLADDVRGLPVYVRFLAHFVAAAACLLTLGLSGWSLLAGT
HHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LAVVWMTNLYNFMDGADGLAGGMAVIGFGALALAAWLGDAPVLAAFCAAPAAAALAFLRF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
NFPPARLFMGDAGSIPLGFMAATLGILGARQGVWPWAFPLIVFSPFIVDATATLARRASR
CCCHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GEKVWRAHRSHYYQRVVLLGASHRQLAVAAWGLMLAMAALGFLLRSFPQQATALLILSAA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYLLIFFAIDRRWRLARNEV
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]