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The map label for this gene is yajL [H]

Identifier: 74317863

GI number: 74317863

Start: 1940861

End: 1941406

Strand: Reverse

Name: yajL [H]

Synonym: Tbd_1845

Alternate gene names: 74317863

Gene position: 1941406-1940861 (Counterclockwise)

Preceding gene: 74317864

Following gene: 74317862

Centisome position: 66.72

GC content: 67.95

Gene sequence:

>546_bases
ATGGCCAAGGTTCTGGTTCCGCTGGCGGACGGCTGTGAAGAGCTCGAAGCCGTCACCATTATCGACTTGCTGCGGCGCGC
CGGCGTCGAGGTCATCGTCGCGGGCCTGAAGCCCGGCGTGGTCAAGGCGAGTCGCGGCGTTCAGCTCGTGCCGGACGTGA
CGCTCGATCAGGCGCTCGCCGACGCCTACGACATGGTCGTACTGCCGGGCGGGATGCCGGGCGCGGCGCACCTCAAGGAC
GACGTACGCGTCGTCGACCTGCTGAAGAAGATGGCGTCGGCCGGGAAATATACCGCAGCCATCTGCGCCGCGCCGATGGT
GCTGGCCGAAGCGGGGCTGTTGCGCGGCAAACAGGCGACGAGCTACCCGGGCTTTCTCGACGGTGTTCCCGACGTCACCT
TGCGCGCCGAGGCGGTCGTTCAGGACGGCACGGTGCTGACCTCGCGCGGTCCCGGAACGGCGATGGATTTCGCGCTGCAA
CTGGTCGAAACCCTCGTCGGCCGCGCCAAGCGCGAGCAGGTCGAAACGGCGCTGGTCAGACCGTAG

Upstream 100 bases:

>100_bases
GCGACGTGCTGCAGGAGACGATCGCGCTGGTCAAGAAGAGCGTCAGCGATTTTCCGCTGCAATATCAGAATTTCCGCGAC
TGAGTGATCGGGAGGCGAGA

Downstream 100 bases:

>100_bases
CCGGCGGCGTCGCCGGATTGTTATCATGAGGGCCTACGCCCAGCCGATTCGGAGACCAGCATGCAAATCCGCGAGATCCT
CACCCTCAAGAGCGACGAAA

Product: putative protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MAKVLVPLADGCEELEAVTIIDLLRRAGVEVIVAGLKPGVVKASRGVQLVPDVTLDQALADAYDMVVLPGGMPGAAHLKD
DVRVVDLLKKMASAGKYTAAICAAPMVLAEAGLLRGKQATSYPGFLDGVPDVTLRAEAVVQDGTVLTSRGPGTAMDFALQ
LVETLVGRAKREQVETALVRP

Sequences:

>Translated_181_residues
MAKVLVPLADGCEELEAVTIIDLLRRAGVEVIVAGLKPGVVKASRGVQLVPDVTLDQALADAYDMVVLPGGMPGAAHLKD
DVRVVDLLKKMASAGKYTAAICAAPMVLAEAGLLRGKQATSYPGFLDGVPDVTLRAEAVVQDGTVLTSRGPGTAMDFALQ
LVETLVGRAKREQVETALVRP
>Mature_180_residues
AKVLVPLADGCEELEAVTIIDLLRRAGVEVIVAGLKPGVVKASRGVQLVPDVTLDQALADAYDMVVLPGGMPGAAHLKDD
VRVVDLLKKMASAGKYTAAICAAPMVLAEAGLLRGKQATSYPGFLDGVPDVTLRAEAVVQDGTVLTSRGPGTAMDFALQL
VETLVGRAKREQVETALVRP

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=182, Percent_Identity=41.2087912087912, Blast_Score=117, Evalue=6e-27,
Organism=Homo sapiens, GI31543380, Length=182, Percent_Identity=41.2087912087912, Blast_Score=117, Evalue=6e-27,
Organism=Escherichia coli, GI87081736, Length=184, Percent_Identity=41.304347826087, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI87082219, Length=154, Percent_Identity=29.8701298701299, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531319, Length=178, Percent_Identity=38.7640449438202, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17558714, Length=182, Percent_Identity=35.1648351648352, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI28571932, Length=178, Percent_Identity=46.6292134831461, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24653499, Length=179, Percent_Identity=43.5754189944134, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 18856; Mature: 18725

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVLVPLADGCEELEAVTIIDLLRRAGVEVIVAGLKPGVVKASRGVQLVPDVTLDQALA
CCEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCEECCCCHHHHHHH
DAYDMVVLPGGMPGAAHLKDDVRVVDLLKKMASAGKYTAAICAAPMVLAEAGLLRGKQAT
HHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
SYPGFLDGVPDVTLRAEAVVQDGTVLTSRGPGTAMDFALQLVETLVGRAKREQVETALVR
CCCCCCCCCCCCEEHHHHEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
P
C
>Mature Secondary Structure 
AKVLVPLADGCEELEAVTIIDLLRRAGVEVIVAGLKPGVVKASRGVQLVPDVTLDQALA
CEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCEECCCCHHHHHHH
DAYDMVVLPGGMPGAAHLKDDVRVVDLLKKMASAGKYTAAICAAPMVLAEAGLLRGKQAT
HHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
SYPGFLDGVPDVTLRAEAVVQDGTVLTSRGPGTAMDFALQLVETLVGRAKREQVETALVR
CCCCCCCCCCCCEEHHHHEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]