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The map label for this gene is traD [H]

Identifier: 74317839

GI number: 74317839

Start: 1922143

End: 1923840

Strand: Reverse

Name: traD [H]

Synonym: Tbd_1821

Alternate gene names: 74317839

Gene position: 1923840-1922143 (Counterclockwise)

Preceding gene: 74317842

Following gene: 74317838

Centisome position: 66.12

GC content: 61.66

Gene sequence:

>1698_bases
ATGGGGACAAAACAGCGAATTTCAGATGGGCTTTTTCGCGCCAAACTGCTCACAGGCAGCATTATTCTCGGCGCATTTCT
GGGCGTCACCACCTACATTTTTTGGCTGAGCGGCTGGGCCGGCATGGACTTGATCCAGCTCGCCCGGGGTGGTCTGTACG
TGTACCAGCGCGCCCCCGGCATGCTCGGCCTCGCCGCGTTCGGCGGGGCGTTTGGCCTAGGCTGGATCGCCTGGATGTTT
GCCTGGCGCCCTGGCGCCGCCCGCCCCGGCGACGCGGACGACGATGCCGATAACCTGCGCGGTCAGCAGCTTGTGACCGT
CGCCGAAATCAAAAAACAAATCCGGAGTGCGAAAACAAAAACACGTCTGGAAATCGGCGGCGTACCGATCCCCATTTATG
TAGAAGATGGGGGGTTTTTACTGACCGGCTCTCCCGGCACCGGTAAATCCCAGGCGACCACAAAAATGCTCGACACCCTG
CAAGCCGGCGGTCACCGCGCGGTGATCGCTGACGCCGAGGGCATTTTTTATTCTCGGTATGCCGGAGACGGCGCTGTGCT
TTTTAATCCCCTCGATCGCCGTAGCGTGTCGTGGAGCCCGCTGGCTGAACTGAAATCGCCGCAGGACTGCTCTGCGCTGG
CCAAATCGCTCATCCCCGACGGTCATGGGGCGGAGGCGAGCTGGAACGATGCAGCGCAGACTGTTTTGGAAGGGTTGCTG
CGCAGGTGCTGGGAAACCAGCAAGACGAACGCCGAGCTTTATCGCCTGGCTTGTGTTGCCGACATAGAAGAGCTGCAGCA
GCTGTTGGCAGGCACCGCCGCGATGACGGTCGTCGGAAACGCGAGGTACTTCGGCGAGGTCCGTCCCGGACTTGGCCGAT
ATCTCCGGTGTTTTGAGCATCTTGATCCTGCTGCAGGACGGGCCAGTTTTTCCGTCCGCGACTTCATCACCGAAGAAACC
GGCTGGCTCTTTATCTCGTACACCCAAGAGCAGCGGGCCGCGTTGCTGCCCCTGATTCAATGCACGCTGGACGTTGCCAG
CCGGGCCATTCTCAGCTTGCCGCATACCACGGGGGACCGGAGCAAGCTGCGGCGGACCTGGCTTGTGTTAGATGAGTTGC
CGCTGCTTGGTCGCATCATGTCCCTTATCCCTTTGCTCACCAACGGCTCGAAGCACGGTGCCGCAGTGATTGCGACGGCC
CAGACAATCGCGCTGTTCAGAGAAGCTTATGGCCATGACGCGACGCAGACGATTTTGGCGACGCTAGGCACCTGGCTGAC
CCTCAGAGTCAGCGACGCCGAGACTGCTGAGTACATGTCTAAATCGCTCGGCGACGAGGAAGTCCGTCGCGTCGTCGCCA
GCGGCGGGAAAAACGATTCTGGAAAGTCTGATAACTGGTCTGAGCAGCACAGCACGCGACGCGTGGTGATGCCGTCGCAG
CTGCAAAACCTGCCCCGCCTCCATGGCTACCTCAACATTTCTGGGCCGCTGCCGGTCTGCGCCGTGACGTTGCCGTACGC
CGACGAGCGTGAGCCAGCCGCCCCGGCATATGAGCCCGCGCCGCTACGGTCGGCGGTCCCCGTGCCCGTGTCGGCTGCCG
TCACTAGTGAGGCCGACCCCAGCACTGTCGAGGGCGACGGCAACACCACCGACACCACGGCTGATAGCGCCGACGTGCCG
TTTACTCTGGAGCGATAA

Upstream 100 bases:

>100_bases
CGCATCCGTGCGACAGGAAGTGGATCAAAAAGTCAGCCGCGACGACTTGGCGGCCGCTACTAATTATTTGGCCGACCGTA
TCAAAAAACAGGGGTAAATC

Downstream 100 bases:

>100_bases
CCATGGTCTGCACAGTCAGCGCTATCAAAACCGCCGGCGTGGCGGCTGAGTACTACGCTCAGACAGACGACTATTATCGC
GATCGGGGGCATGCCCCGAC

Product: putative type IV secretory pathway VirD4 component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MGTKQRISDGLFRAKLLTGSIILGAFLGVTTYIFWLSGWAGMDLIQLARGGLYVYQRAPGMLGLAAFGGAFGLGWIAWMF
AWRPGAARPGDADDDADNLRGQQLVTVAEIKKQIRSAKTKTRLEIGGVPIPIYVEDGGFLLTGSPGTGKSQATTKMLDTL
QAGGHRAVIADAEGIFYSRYAGDGAVLFNPLDRRSVSWSPLAELKSPQDCSALAKSLIPDGHGAEASWNDAAQTVLEGLL
RRCWETSKTNAELYRLACVADIEELQQLLAGTAAMTVVGNARYFGEVRPGLGRYLRCFEHLDPAAGRASFSVRDFITEET
GWLFISYTQEQRAALLPLIQCTLDVASRAILSLPHTTGDRSKLRRTWLVLDELPLLGRIMSLIPLLTNGSKHGAAVIATA
QTIALFREAYGHDATQTILATLGTWLTLRVSDAETAEYMSKSLGDEEVRRVVASGGKNDSGKSDNWSEQHSTRRVVMPSQ
LQNLPRLHGYLNISGPLPVCAVTLPYADEREPAAPAYEPAPLRSAVPVPVSAAVTSEADPSTVEGDGNTTDTTADSADVP
FTLER

Sequences:

>Translated_565_residues
MGTKQRISDGLFRAKLLTGSIILGAFLGVTTYIFWLSGWAGMDLIQLARGGLYVYQRAPGMLGLAAFGGAFGLGWIAWMF
AWRPGAARPGDADDDADNLRGQQLVTVAEIKKQIRSAKTKTRLEIGGVPIPIYVEDGGFLLTGSPGTGKSQATTKMLDTL
QAGGHRAVIADAEGIFYSRYAGDGAVLFNPLDRRSVSWSPLAELKSPQDCSALAKSLIPDGHGAEASWNDAAQTVLEGLL
RRCWETSKTNAELYRLACVADIEELQQLLAGTAAMTVVGNARYFGEVRPGLGRYLRCFEHLDPAAGRASFSVRDFITEET
GWLFISYTQEQRAALLPLIQCTLDVASRAILSLPHTTGDRSKLRRTWLVLDELPLLGRIMSLIPLLTNGSKHGAAVIATA
QTIALFREAYGHDATQTILATLGTWLTLRVSDAETAEYMSKSLGDEEVRRVVASGGKNDSGKSDNWSEQHSTRRVVMPSQ
LQNLPRLHGYLNISGPLPVCAVTLPYADEREPAAPAYEPAPLRSAVPVPVSAAVTSEADPSTVEGDGNTTDTTADSADVP
FTLER
>Mature_564_residues
GTKQRISDGLFRAKLLTGSIILGAFLGVTTYIFWLSGWAGMDLIQLARGGLYVYQRAPGMLGLAAFGGAFGLGWIAWMFA
WRPGAARPGDADDDADNLRGQQLVTVAEIKKQIRSAKTKTRLEIGGVPIPIYVEDGGFLLTGSPGTGKSQATTKMLDTLQ
AGGHRAVIADAEGIFYSRYAGDGAVLFNPLDRRSVSWSPLAELKSPQDCSALAKSLIPDGHGAEASWNDAAQTVLEGLLR
RCWETSKTNAELYRLACVADIEELQQLLAGTAAMTVVGNARYFGEVRPGLGRYLRCFEHLDPAAGRASFSVRDFITEETG
WLFISYTQEQRAALLPLIQCTLDVASRAILSLPHTTGDRSKLRRTWLVLDELPLLGRIMSLIPLLTNGSKHGAAVIATAQ
TIALFREAYGHDATQTILATLGTWLTLRVSDAETAEYMSKSLGDEEVRRVVASGGKNDSGKSDNWSEQHSTRRVVMPSQL
QNLPRLHGYLNISGPLPVCAVTLPYADEREPAAPAYEPAPLRSAVPVPVSAAVTSEADPSTVEGDGNTTDTTADSADVPF
TLER

Specific function: TraD is a cell envelope protein. The function of traD is unknown but it is essential for DNA transfer. It may form or may be part of a non-specific pore for DNA export, or it may directly energizes DNA transport [H]

COG id: COG3505

COG function: function code U; Type IV secretory pathway, VirD4 components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To traD of plasmid F [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014128
- InterPro:   IPR019476
- InterPro:   IPR022585 [H]

Pfam domain/function: PF12615 TraD_N; PF10412 TrwB_AAD_bind [H]

EC number: NA

Molecular weight: Translated: 60868; Mature: 60737

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTKQRISDGLFRAKLLTGSIILGAFLGVTTYIFWLSGWAGMDLIQLARGGLYVYQRAPG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEECCCC
MLGLAAFGGAFGLGWIAWMFAWRPGAARPGDADDDADNLRGQQLVTVAEIKKQIRSAKTK
CEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
TRLEIGGVPIPIYVEDGGFLLTGSPGTGKSQATTKMLDTLQAGGHRAVIADAEGIFYSRY
CEEEECCEEEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEE
AGDGAVLFNPLDRRSVSWSPLAELKSPQDCSALAKSLIPDGHGAEASWNDAAQTVLEGLL
CCCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
RRCWETSKTNAELYRLACVADIEELQQLLAGTAAMTVVGNARYFGEVRPGLGRYLRCFEH
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCHHCCCCCHHHHHHHHHHHH
LDPAAGRASFSVRDFITEETGWLFISYTQEQRAALLPLIQCTLDVASRAILSLPHTTGDR
CCCCCCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
SKLRRTWLVLDELPLLGRIMSLIPLLTNGSKHGAAVIATAQTIALFREAYGHDATQTILA
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHH
TLGTWLTLRVSDAETAEYMSKSLGDEEVRRVVASGGKNDSGKSDNWSEQHSTRRVVMPSQ
HHCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCEEECHHH
LQNLPRLHGYLNISGPLPVCAVTLPYADEREPAAPAYEPAPLRSAVPVPVSAAVTSEADP
HHCCHHHCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
STVEGDGNTTDTTADSADVPFTLER
CEECCCCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure 
GTKQRISDGLFRAKLLTGSIILGAFLGVTTYIFWLSGWAGMDLIQLARGGLYVYQRAPG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEECCCC
MLGLAAFGGAFGLGWIAWMFAWRPGAARPGDADDDADNLRGQQLVTVAEIKKQIRSAKTK
CEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
TRLEIGGVPIPIYVEDGGFLLTGSPGTGKSQATTKMLDTLQAGGHRAVIADAEGIFYSRY
CEEEECCEEEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEE
AGDGAVLFNPLDRRSVSWSPLAELKSPQDCSALAKSLIPDGHGAEASWNDAAQTVLEGLL
CCCCEEEECCCCCCCCCCCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
RRCWETSKTNAELYRLACVADIEELQQLLAGTAAMTVVGNARYFGEVRPGLGRYLRCFEH
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCHHCCCCCHHHHHHHHHHHH
LDPAAGRASFSVRDFITEETGWLFISYTQEQRAALLPLIQCTLDVASRAILSLPHTTGDR
CCCCCCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
SKLRRTWLVLDELPLLGRIMSLIPLLTNGSKHGAAVIATAQTIALFREAYGHDATQTILA
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHH
TLGTWLTLRVSDAETAEYMSKSLGDEEVRRVVASGGKNDSGKSDNWSEQHSTRRVVMPSQ
HHCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHCCCEEECHHH
LQNLPRLHGYLNISGPLPVCAVTLPYADEREPAAPAYEPAPLRSAVPVPVSAAVTSEADP
HHCCHHHCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
STVEGDGNTTDTTADSADVPFTLER
CEECCCCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2164585 [H]