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The map label for this gene is galE [H]

Identifier: 74317792

GI number: 74317792

Start: 1873642

End: 1874652

Strand: Reverse

Name: galE [H]

Synonym: Tbd_1774

Alternate gene names: 74317792

Gene position: 1874652-1873642 (Counterclockwise)

Preceding gene: 74317793

Following gene: 74317791

Centisome position: 64.43

GC content: 65.78

Gene sequence:

>1011_bases
TTGAGAGTTCTTTTGACAGGCGGTGCCGGTTACATCGGATCGCATACAGCCGTGGAGTGCCTCGCGGCCGGACACGACGT
CGTCGTGTTCGACAATCTTTCCAACAGCAGTGAAAAATCGCTCGAGCGTGTGGCCCGGATCGCGGGCAAGCCCGTGAGTT
TCGTGCGCGGCGACATTCGCGATCGGCACGCGCTTCGCAAGCTCTTCGCGGAACACGCGGTCGATGCGGTCGTGCATTTC
GCGGGGCTCAAGGCGGTGGGCGAGTCGGTCGAGCATCCCTTGCGCTACTACGACAACAATATCGGCGGCAGCATCGCCCT
GTTCGAGACGATGGCCGAGGTCGGGCTGAAGACAATCGTGTTCTCGTCGTCGGCGACGGTCTACGGCGACCCGGTCCGGG
TGCCGATCACCGAAGATTTTCCGCTGTCGGCGACCAATCCCTACGGCCGCTCGAAGCTCTTCATCGAGGAGATGCTGCGC
GACATCGCGCGGTCGGACGGCGGTTGGCACATCGCGCTGCTGCGCTATTTCAATCCGGTCGGCGCCCATGCGTCGGGCCT
GATCGGCGAGGACCCGCGCGGTATTCCCAACAATCTCATGCCCTACATCGCTCAGGTCGCGGTCGGGCGGCGTCCGCATC
TCAACGTATTCGGCGGCGACTACCCGACGCCGGATGGCACAGGCGTGCGCGACTACATCCACGTCGTCGATCTCGCCCGC
GGCCACGTCGCGGCCTTGGGCAGACTGCAAAAAACGGCGGGCGTGCAGACCTGGAATCTCGGGACCGGGCGCGGCGTGAG
CGTGCTCGACATGGTGCGCGCATTCGAGGCGGCCAGCGGCCGTGCGATCCCCTATCGCATCGTCGAGCGTCGCGCAGGCG
ATGTCGCGCAGTGCTGGGCCGACCCGTCGTGCGCGGCGCGCGACCTCGGCTGGCGGGCAGAATACGATTTGCCGCGCATG
TGCGAGGACGCTTGGCGCTGGCAGCAAGGCAACCCCGAGGGCTACGCCTGA

Upstream 100 bases:

>100_bases
CCGCACAGCCGGCCATGGACACGTGCCGCAGGCTGACGGTTTGTGCGCGGCGCCCAGCCTACTGACATCCGCATGGCGGC
AACAGGAGAAGGAGAGGCAG

Downstream 100 bases:

>100_bases
AGACGCCCGCCCCGGCGCGCCGATGCGGGCCAGGCGAGATCAGGCGCGCTATGATCTGCTGACCGGGGGCGATCCCGGCG
CAGACAATCACGGAGATACC

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MRVLLTGGAGYIGSHTAVECLAAGHDVVVFDNLSNSSEKSLERVARIAGKPVSFVRGDIRDRHALRKLFAEHAVDAVVHF
AGLKAVGESVEHPLRYYDNNIGGSIALFETMAEVGLKTIVFSSSATVYGDPVRVPITEDFPLSATNPYGRSKLFIEEMLR
DIARSDGGWHIALLRYFNPVGAHASGLIGEDPRGIPNNLMPYIAQVAVGRRPHLNVFGGDYPTPDGTGVRDYIHVVDLAR
GHVAALGRLQKTAGVQTWNLGTGRGVSVLDMVRAFEAASGRAIPYRIVERRAGDVAQCWADPSCAARDLGWRAEYDLPRM
CEDAWRWQQGNPEGYA

Sequences:

>Translated_336_residues
MRVLLTGGAGYIGSHTAVECLAAGHDVVVFDNLSNSSEKSLERVARIAGKPVSFVRGDIRDRHALRKLFAEHAVDAVVHF
AGLKAVGESVEHPLRYYDNNIGGSIALFETMAEVGLKTIVFSSSATVYGDPVRVPITEDFPLSATNPYGRSKLFIEEMLR
DIARSDGGWHIALLRYFNPVGAHASGLIGEDPRGIPNNLMPYIAQVAVGRRPHLNVFGGDYPTPDGTGVRDYIHVVDLAR
GHVAALGRLQKTAGVQTWNLGTGRGVSVLDMVRAFEAASGRAIPYRIVERRAGDVAQCWADPSCAARDLGWRAEYDLPRM
CEDAWRWQQGNPEGYA
>Mature_336_residues
MRVLLTGGAGYIGSHTAVECLAAGHDVVVFDNLSNSSEKSLERVARIAGKPVSFVRGDIRDRHALRKLFAEHAVDAVVHF
AGLKAVGESVEHPLRYYDNNIGGSIALFETMAEVGLKTIVFSSSATVYGDPVRVPITEDFPLSATNPYGRSKLFIEEMLR
DIARSDGGWHIALLRYFNPVGAHASGLIGEDPRGIPNNLMPYIAQVAVGRRPHLNVFGGDYPTPDGTGVRDYIHVVDLAR
GHVAALGRLQKTAGVQTWNLGTGRGVSVLDMVRAFEAASGRAIPYRIVERRAGDVAQCWADPSCAARDLGWRAEYDLPRM
CEDAWRWQQGNPEGYA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=59.8240469208211, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=59.8240469208211, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=59.8240469208211, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI7657641, Length=276, Percent_Identity=25.7246376811594, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=55.952380952381, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI48994969, Length=356, Percent_Identity=27.8089887640449, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788353, Length=360, Percent_Identity=25.8333333333333, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=51.1560693641619, Blast_Score=367, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=50.8620689655172, Blast_Score=367, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17568069, Length=283, Percent_Identity=28.2685512367491, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=53.8011695906433, Blast_Score=372, Evalue=1e-104,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=58.3090379008746, Blast_Score=415, Evalue=1e-116,
Organism=Drosophila melanogaster, GI21356223, Length=265, Percent_Identity=25.2830188679245, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36595; Mature: 36595

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLTGGAGYIGSHTAVECLAAGHDVVVFDNLSNSSEKSLERVARIAGKPVSFVRGDIR
CEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHH
DRHALRKLFAEHAVDAVVHFAGLKAVGESVEHPLRYYDNNIGGSIALFETMAEVGLKTIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEE
FSSSATVYGDPVRVPITEDFPLSATNPYGRSKLFIEEMLRDIARSDGGWHIALLRYFNPV
EECCCEEECCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHCCCC
GAHASGLIGEDPRGIPNNLMPYIAQVAVGRRPHLNVFGGDYPTPDGTGVRDYIHVVDLAR
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHH
GHVAALGRLQKTAGVQTWNLGTGRGVSVLDMVRAFEAASGRAIPYRIVERRAGDVAQCWA
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHCC
DPSCAARDLGWRAEYDLPRMCEDAWRWQQGNPEGYA
CCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRVLLTGGAGYIGSHTAVECLAAGHDVVVFDNLSNSSEKSLERVARIAGKPVSFVRGDIR
CEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHH
DRHALRKLFAEHAVDAVVHFAGLKAVGESVEHPLRYYDNNIGGSIALFETMAEVGLKTIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEE
FSSSATVYGDPVRVPITEDFPLSATNPYGRSKLFIEEMLRDIARSDGGWHIALLRYFNPV
EECCCEEECCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHCCCC
GAHASGLIGEDPRGIPNNLMPYIAQVAVGRRPHLNVFGGDYPTPDGTGVRDYIHVVDLAR
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHH
GHVAALGRLQKTAGVQTWNLGTGRGVSVLDMVRAFEAASGRAIPYRIVERRAGDVAQCWA
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHCC
DPSCAARDLGWRAEYDLPRMCEDAWRWQQGNPEGYA
CCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]