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The map label for this gene is hbpA [H]

Identifier: 74317689

GI number: 74317689

Start: 1755715

End: 1757856

Strand: Reverse

Name: hbpA [H]

Synonym: Tbd_1671

Alternate gene names: 74317689

Gene position: 1757856-1755715 (Counterclockwise)

Preceding gene: 74317691

Following gene: 74317688

Centisome position: 60.41

GC content: 64.43

Gene sequence:

>2142_bases
ATGACGCGTACAGGCTCGGTACTGCTCGGACTCGCTTTGCTCGCCGGATGCGGCGACACGTGGAACAACCCATACCCGGA
CAGTCAAGCCGCCGCCCCGGTTCTTTATAGCGCGTTTTCGGAACGTCCGAAGCATCTCGATCCAGCGCGTTCGTATAGCG
CAAACGAGGTCGAATTCACCGGACAGATCTACGAGCCGCCGCTGCAATACCATTTCCTCAAACGTCCTTACACCCTCGTC
CCGCTGACGGCGGCGCGCGTGCCTGAGCCGCGCTACTACGATGCGTCCGGCAAGCGGTTGCCCGACGACGCAGCGTCGTC
GCGCATCGCCGAGAGCGTGTACGAAATCCGCGTCCGTCCCGGCATACGCTATCAACCGCACCCGGCCTTCGCGCGTGACG
AAGCCGGGCGCTATCGCTATCACGCGCTCGAGTCGGCAGCGCTCGACGGCAAGAGCCGCATCAGCGACTTCGCCCACCAA
GGCACGCGCGAGCTCGTCGCCGCCGACTACGTCTACCAGATCAAGCGGCTTGCCCATCCCGGCCTCAGTTCGCCGATTTT
CGGCCTGATGAGCGAACACATCGTCGGACTCAAGGCGCTTGGCGCGGCACTCGAGAAGGCGGCGCAGGCGCAACCCGGAC
GCCGGCTGGATCTCGATCGCTTTCCGCTTGCCGGCGCGCAGGTGGTCGATCGCTACACGTATCGCATCCGCATCCGCGGC
AAGTATCCGCAGTTCATCTACTGGCTCGCGATGCCGTTTTTCGCGCCGGTGCCGTGGGAGGCCGAAACTTTCTACGCCCA
GCCGGGCATGGCCGACAGGAACCTCACGCTCGACTGGCAGCCGGTCGGAACCGGGCCCTACTATCTTGCCGAGAACGATC
CCAACAGGCGGATGGTGTTGAAGCGCAACCCGTATTTCCACGGCGAGGTCTATCCGGGCGAAGGCAGCGTGGAGGATCGC
GCGGCCGGGCTGCTCGCCGATGCGGGCAAGCGCCTGCCGCTCGTCGACGAGGCCGTTTACAGTCTGGAAAAGGAGACGAT
CCCGTACTGGAGCAAGTTTCTCCAGGGCTATTACGACAGCTCGGGTATCAGTTCCGACAGCTTCGACCAGGCGGTCCGTT
TTTCGGCCAAGGGCGAACCCGAGTTGACCGCCAGCATGCGCGCGCAGGATATCCATCTCATTACCGCGGTCGCCGCGTCG
ATCTGGTACGTCGGCTTCAACATGCTCGATCCGGTCGTCGGCGGGCTCGGCGAGGATCGTCGCAAGCTGCGCCAGGCGCT
TTCAATCGCTTTCGACTACGACGAATTCATTTCCATTTTCCTCAACGGCCGCGGCATCCCCGCGCAAGGCCCGCTGCCCC
CGGGCCTGTTCGGCTATGTCGAGGGCCCGGCCGGCCTCAACCCCTACGTCTACGAGGCGCGCGGCGAAAAAATCGAGCGC
CGGCCGATCGAGACCGCGAAGAAGCTGTTGGCCGAGGCGGGCTATCCGAACGGACGTCACGCCAAGACCGGCCAGCCGCT
CGTGCTCTATTTCGACACGATGGCCGCGGGGCCCGACGCCAAGTCGCGGCTCGACTGGATGAAGAAGCAGCTCGACAAGC
TCAACGTGCAACTCGTGGTACGCGGAACCGATTACAACCGCTTCCAGGACAAGATCCGCAAGGGCAACGCCCAGCTCTTC
GAATGGGGCTGGAACGCGGATTATCCCGACCCCGAGAACTTCTTCTTTCTGCTCTACGGGCCGCACAAGAAGGTCAGCAG
CGGCGGCGAGAACGCGGCCAATTACGACAACCCGGAATTCGACCGGCTGTTCGAGCGCATGAAGGACATGGACAACGGCC
CCGAGCGTCAGGCCGTGATCGACGCGATGCTCGAGATCGTGCGTCGCGACGCGCCGTGGATCTTCGCGTACTACCCGAAG
TCCTTCGGCCTGCGCCACGGCTGGGTCCACAACGTCAAGCCCAATCTGATGGCGAACAACACCCTGAAGTACCGGCGCAT
CGATCCTGCGCTGCGCGAGGAACGGCGCGCGGCCTGGAACCGGCCGGTGCTGTGGCCTGTCGCCTTGCTCGTGGTCGGGC
TCGTCGTGCTGATCGCGCCCGCGGCGAGCGCGTGGCGGCGGCATGAGCGGAAGGTCGCCTGA

Upstream 100 bases:

>100_bases
TTTTCCTGCAAGAAATCCCATGATGGTCTCGAAGCGAAGAGTTGAGTAGGGCGAGATTATAACGGCTGACGTTGACGGCG
CGCTTGGGTACACTGGCGCC

Downstream 100 bases:

>100_bases
TGCTCGGCTACATCCTGCGCCGTCTCTTCTATGCCGTCCCGATCCTGATCGGCGTCAACCTGCTCACCTTCGCCTTGTTC
TTCGTCGTCAACACGCCCGA

Product: oligopeptide ABC transporter periplasmic protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 713; Mature: 712

Protein sequence:

>713_residues
MTRTGSVLLGLALLAGCGDTWNNPYPDSQAAAPVLYSAFSERPKHLDPARSYSANEVEFTGQIYEPPLQYHFLKRPYTLV
PLTAARVPEPRYYDASGKRLPDDAASSRIAESVYEIRVRPGIRYQPHPAFARDEAGRYRYHALESAALDGKSRISDFAHQ
GTRELVAADYVYQIKRLAHPGLSSPIFGLMSEHIVGLKALGAALEKAAQAQPGRRLDLDRFPLAGAQVVDRYTYRIRIRG
KYPQFIYWLAMPFFAPVPWEAETFYAQPGMADRNLTLDWQPVGTGPYYLAENDPNRRMVLKRNPYFHGEVYPGEGSVEDR
AAGLLADAGKRLPLVDEAVYSLEKETIPYWSKFLQGYYDSSGISSDSFDQAVRFSAKGEPELTASMRAQDIHLITAVAAS
IWYVGFNMLDPVVGGLGEDRRKLRQALSIAFDYDEFISIFLNGRGIPAQGPLPPGLFGYVEGPAGLNPYVYEARGEKIER
RPIETAKKLLAEAGYPNGRHAKTGQPLVLYFDTMAAGPDAKSRLDWMKKQLDKLNVQLVVRGTDYNRFQDKIRKGNAQLF
EWGWNADYPDPENFFFLLYGPHKKVSSGGENAANYDNPEFDRLFERMKDMDNGPERQAVIDAMLEIVRRDAPWIFAYYPK
SFGLRHGWVHNVKPNLMANNTLKYRRIDPALREERRAAWNRPVLWPVALLVVGLVVLIAPAASAWRRHERKVA

Sequences:

>Translated_713_residues
MTRTGSVLLGLALLAGCGDTWNNPYPDSQAAAPVLYSAFSERPKHLDPARSYSANEVEFTGQIYEPPLQYHFLKRPYTLV
PLTAARVPEPRYYDASGKRLPDDAASSRIAESVYEIRVRPGIRYQPHPAFARDEAGRYRYHALESAALDGKSRISDFAHQ
GTRELVAADYVYQIKRLAHPGLSSPIFGLMSEHIVGLKALGAALEKAAQAQPGRRLDLDRFPLAGAQVVDRYTYRIRIRG
KYPQFIYWLAMPFFAPVPWEAETFYAQPGMADRNLTLDWQPVGTGPYYLAENDPNRRMVLKRNPYFHGEVYPGEGSVEDR
AAGLLADAGKRLPLVDEAVYSLEKETIPYWSKFLQGYYDSSGISSDSFDQAVRFSAKGEPELTASMRAQDIHLITAVAAS
IWYVGFNMLDPVVGGLGEDRRKLRQALSIAFDYDEFISIFLNGRGIPAQGPLPPGLFGYVEGPAGLNPYVYEARGEKIER
RPIETAKKLLAEAGYPNGRHAKTGQPLVLYFDTMAAGPDAKSRLDWMKKQLDKLNVQLVVRGTDYNRFQDKIRKGNAQLF
EWGWNADYPDPENFFFLLYGPHKKVSSGGENAANYDNPEFDRLFERMKDMDNGPERQAVIDAMLEIVRRDAPWIFAYYPK
SFGLRHGWVHNVKPNLMANNTLKYRRIDPALREERRAAWNRPVLWPVALLVVGLVVLIAPAASAWRRHERKVA
>Mature_712_residues
TRTGSVLLGLALLAGCGDTWNNPYPDSQAAAPVLYSAFSERPKHLDPARSYSANEVEFTGQIYEPPLQYHFLKRPYTLVP
LTAARVPEPRYYDASGKRLPDDAASSRIAESVYEIRVRPGIRYQPHPAFARDEAGRYRYHALESAALDGKSRISDFAHQG
TRELVAADYVYQIKRLAHPGLSSPIFGLMSEHIVGLKALGAALEKAAQAQPGRRLDLDRFPLAGAQVVDRYTYRIRIRGK
YPQFIYWLAMPFFAPVPWEAETFYAQPGMADRNLTLDWQPVGTGPYYLAENDPNRRMVLKRNPYFHGEVYPGEGSVEDRA
AGLLADAGKRLPLVDEAVYSLEKETIPYWSKFLQGYYDSSGISSDSFDQAVRFSAKGEPELTASMRAQDIHLITAVAASI
WYVGFNMLDPVVGGLGEDRRKLRQALSIAFDYDEFISIFLNGRGIPAQGPLPPGLFGYVEGPAGLNPYVYEARGEKIERR
PIETAKKLLAEAGYPNGRHAKTGQPLVLYFDTMAAGPDAKSRLDWMKKQLDKLNVQLVVRGTDYNRFQDKIRKGNAQLFE
WGWNADYPDPENFFFLLYGPHKKVSSGGENAANYDNPEFDRLFERMKDMDNGPERQAVIDAMLEIVRRDAPWIFAYYPKS
FGLRHGWVHNVKPNLMANNTLKYRRIDPALREERRAAWNRPVLWPVALLVVGLVVLIAPAASAWRRHERKVA

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=492, Percent_Identity=24.1869918699187, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789966, Length=422, Percent_Identity=21.3270142180095, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1789397, Length=475, Percent_Identity=20.4210526315789, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 80479; Mature: 80348

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTGSVLLGLALLAGCGDTWNNPYPDSQAAAPVLYSAFSERPKHLDPARSYSANEVEFT
CCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEE
GQIYEPPLQYHFLKRPYTLVPLTAARVPEPRYYDASGKRLPDDAASSRIAESVYEIRVRP
CEECCCCHHHHHHCCCCEEEEEHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHEEECC
GIRYQPHPAFARDEAGRYRYHALESAALDGKSRISDFAHQGTRELVAADYVYQIKRLAHP
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
GLSSPIFGLMSEHIVGLKALGAALEKAAQAQPGRRLDLDRFPLAGAQVVDRYTYRIRIRG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHEEEEEEEEEEC
KYPQFIYWLAMPFFAPVPWEAETFYAQPGMADRNLTLDWQPVGTGPYYLAENDPNRRMVL
CCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCEEEECCCCCCEEEE
KRNPYFHGEVYPGEGSVEDRAAGLLADAGKRLPLVDEAVYSLEKETIPYWSKFLQGYYDS
ECCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCC
SGISSDSFDQAVRFSAKGEPELTASMRAQDIHLITAVAASIWYVGFNMLDPVVGGLGEDR
CCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RKLRQALSIAFDYDEFISIFLNGRGIPAQGPLPPGLFGYVEGPAGLNPYVYEARGEKIER
HHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCEEECCCCCHHHC
RPIETAKKLLAEAGYPNGRHAKTGQPLVLYFDTMAAGPDAKSRLDWMKKQLDKLNVQLVV
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEE
RGTDYNRFQDKIRKGNAQLFEWGWNADYPDPENFFFLLYGPHKKVSSGGENAANYDNPEF
ECCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCHHH
DRLFERMKDMDNGPERQAVIDAMLEIVRRDAPWIFAYYPKSFGLRHGWVHNVKPNLMANN
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEECC
TLKYRRIDPALREERRAAWNRPVLWPVALLVVGLVVLIAPAASAWRRHERKVA
CEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
>Mature Secondary Structure 
TRTGSVLLGLALLAGCGDTWNNPYPDSQAAAPVLYSAFSERPKHLDPARSYSANEVEFT
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEE
GQIYEPPLQYHFLKRPYTLVPLTAARVPEPRYYDASGKRLPDDAASSRIAESVYEIRVRP
CEECCCCHHHHHHCCCCEEEEEHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHEEECC
GIRYQPHPAFARDEAGRYRYHALESAALDGKSRISDFAHQGTRELVAADYVYQIKRLAHP
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
GLSSPIFGLMSEHIVGLKALGAALEKAAQAQPGRRLDLDRFPLAGAQVVDRYTYRIRIRG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHEEEEEEEEEEC
KYPQFIYWLAMPFFAPVPWEAETFYAQPGMADRNLTLDWQPVGTGPYYLAENDPNRRMVL
CCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCEEEECCCCCCEEEE
KRNPYFHGEVYPGEGSVEDRAAGLLADAGKRLPLVDEAVYSLEKETIPYWSKFLQGYYDS
ECCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCC
SGISSDSFDQAVRFSAKGEPELTASMRAQDIHLITAVAASIWYVGFNMLDPVVGGLGEDR
CCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RKLRQALSIAFDYDEFISIFLNGRGIPAQGPLPPGLFGYVEGPAGLNPYVYEARGEKIER
HHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCEEECCCCCHHHC
RPIETAKKLLAEAGYPNGRHAKTGQPLVLYFDTMAAGPDAKSRLDWMKKQLDKLNVQLVV
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEE
RGTDYNRFQDKIRKGNAQLFEWGWNADYPDPENFFFLLYGPHKKVSSGGENAANYDNPEF
ECCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCHHH
DRLFERMKDMDNGPERQAVIDAMLEIVRRDAPWIFAYYPKSFGLRHGWVHNVKPNLMANN
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEECC
TLKYRRIDPALREERRAAWNRPVLWPVALLVVGLVVLIAPAASAWRRHERKVA
CEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]