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The map label for this gene is tsr [H]

Identifier: 74317638

GI number: 74317638

Start: 1703684

End: 1705363

Strand: Reverse

Name: tsr [H]

Synonym: Tbd_1620

Alternate gene names: 74317638

Gene position: 1705363-1703684 (Counterclockwise)

Preceding gene: 74317639

Following gene: 74317637

Centisome position: 58.61

GC content: 62.86

Gene sequence:

>1680_bases
TTGAAGATCGGCGCTCGGCTCGGGCTGGGTTTTGCGAGTGTCCTGCTGCTGTTGGTCGTGGTGGCGGTGATTGGCGTCTG
GCGCCTGCAGACGGTCGGAATGATGACCGACTCGCTGGTCAAGAATGAAATGCACAAGGCGCGCATCATCAATGAGTGGG
AAAGCATCATCAATGCCAATGCGGTAAGAGCCCTCGCGGCGGCCAAGACCAATAATCCGGAAACCGAAAAATTTTTCGTG
GACGCGAGTGCCGCGGCCAGCAAGGGCGGCATCGCATTGCAGAAACAGCTCGAGTCGCTGCTCACGGACGCGGAATCCAG
GGCCCTGTTCGCGGCCATCGCGGACAAGCGTAGCGCTTACCTCGCGGCGCGCGACGCCGCGCTCAAGGAAAAAGCGGCCG
GGAATGTTCTGGGCGCAAAGAAGTTCGTCGATGAAGACATGAAGCCCAGGCTGGATGCGTATCTGGAGAGCCTGCACGAC
CTTGCGCGCTATCAGAAGCAGGCTATCGATGCGACCGCAGGGAATATCCATCGGCAGTATGAAAGCGGCCGGATGCTGTT
GATCGGTTTGAGCATCGTGGCGCTCATGATGGGAATCGGCTTCGCGTTCTGGATCACGCGCTCGATCACGCGCCCGATGA
ACCAGGCGGTGAAGGTTGCGCAGACGGTGGCCGCCGGCGACCTGACGAGCCGCATCGAGGTGGAAGGCAAGGATGAAACG
GGCCGATTGCTGCAGGCGCTGAAGGACATGAATGACAGTCTGGTGAAGATTGTCGGCCAGGTACGCCTCGGCACCGACGC
CATCGCCACCGCCTCGAGCGAGATTGCGACGGGGAACCTGGATCTGTCGAGCCGGACGGAAGAACAGGCAAGTTCTCTGG
AAGAGACCGCTTCCTCGATGGAACAGCTCACCTCGACGGTGAAGCAGAACGCGGACCATGCGCGCCAGGCGAATCAGATG
GCGGTCTCGGCCAGCGAAGTGGCGGTCAAGGGCGGAGCGGTCGTCGCGCAAGTGGTCGACACCATGGGCTCGATCAACGA
GTCTTCAAGGAAAATCGTCGACATCATCGCCGTGATCGACGGCATCGCGTTTCAGACCAACATTCTGGCGCTCAATGCGG
CGGTGGAAGCGGCGCGAGCGGGCGAACAGGGGCGGGGCTTCGCGGTGGTTGCCAGCGAGGTACGCAGCCTCGCGCAGCGC
AGTGCGGGTGCGGCCAAGGAAATCAAAACCCTGATAGGCGATTCGGTGGAGAAGGCCGACATAGGCAGCAAACTGGTCGG
TCAGGCGGGCGCCACCATGGACGAGATCGTGGCCAGCGTGAAGCGCGTGACCGACATCATGGGCGAGATCACGGCGGCCA
GCCAGGAACAGAGCGCCGGCATCGAACAGGTCAACCAGGCCATCGCCCAGATGGACGAAGTGACGCAGCAGAATGCCGCC
CTGGTGGAGGAGGCGGCAGCGGCGGCGTCTTCCATGCAGGACCAGGCGGCCAATCTGGCTGAGGCGGTGAGCGTGTTCAG
GCTCGCCGGCGTCAACACGCAGCGCCCGGAACAGCTGACATCGAACGAGCGGATCGCGGCGCTGCCGGCCCGGACCCATA
CGGCCGCGGCACCCGTGGTGCGCACGAAGAAGCTCGCGGCTATCCAGGGTTCAAGCGGCGGCGAGTGGGAAGAGTTCTGA

Upstream 100 bases:

>100_bases
TTGCCGGTATTCGCCGGTTTTCAGCGGATAACCGAATTATTCGAACGTTGCCCTTTCATGACGGGTTAACTTTGGAACTG
GAATTGTGAAAATTACGAAT

Downstream 100 bases:

>100_bases
CCGTCTCGTGGGCCGAGGCATCCGACGAACGGACTACGGATCGATGGTGCGAATGACCTGCCGTGGGGTATCAAGGCAGA
CGGAATCGCGCCGATTTCTA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MKIGARLGLGFASVLLLLVVVAVIGVWRLQTVGMMTDSLVKNEMHKARIINEWESIINANAVRALAAAKTNNPETEKFFV
DASAAASKGGIALQKQLESLLTDAESRALFAAIADKRSAYLAARDAALKEKAAGNVLGAKKFVDEDMKPRLDAYLESLHD
LARYQKQAIDATAGNIHRQYESGRMLLIGLSIVALMMGIGFAFWITRSITRPMNQAVKVAQTVAAGDLTSRIEVEGKDET
GRLLQALKDMNDSLVKIVGQVRLGTDAIATASSEIATGNLDLSSRTEEQASSLEETASSMEQLTSTVKQNADHARQANQM
AVSASEVAVKGGAVVAQVVDTMGSINESSRKIVDIIAVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAQR
SAGAAKEIKTLIGDSVEKADIGSKLVGQAGATMDEIVASVKRVTDIMGEITAASQEQSAGIEQVNQAIAQMDEVTQQNAA
LVEEAAAAASSMQDQAANLAEAVSVFRLAGVNTQRPEQLTSNERIAALPARTHTAAAPVVRTKKLAAIQGSSGGEWEEF

Sequences:

>Translated_559_residues
MKIGARLGLGFASVLLLLVVVAVIGVWRLQTVGMMTDSLVKNEMHKARIINEWESIINANAVRALAAAKTNNPETEKFFV
DASAAASKGGIALQKQLESLLTDAESRALFAAIADKRSAYLAARDAALKEKAAGNVLGAKKFVDEDMKPRLDAYLESLHD
LARYQKQAIDATAGNIHRQYESGRMLLIGLSIVALMMGIGFAFWITRSITRPMNQAVKVAQTVAAGDLTSRIEVEGKDET
GRLLQALKDMNDSLVKIVGQVRLGTDAIATASSEIATGNLDLSSRTEEQASSLEETASSMEQLTSTVKQNADHARQANQM
AVSASEVAVKGGAVVAQVVDTMGSINESSRKIVDIIAVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAQR
SAGAAKEIKTLIGDSVEKADIGSKLVGQAGATMDEIVASVKRVTDIMGEITAASQEQSAGIEQVNQAIAQMDEVTQQNAA
LVEEAAAAASSMQDQAANLAEAVSVFRLAGVNTQRPEQLTSNERIAALPARTHTAAAPVVRTKKLAAIQGSSGGEWEEF
>Mature_559_residues
MKIGARLGLGFASVLLLLVVVAVIGVWRLQTVGMMTDSLVKNEMHKARIINEWESIINANAVRALAAAKTNNPETEKFFV
DASAAASKGGIALQKQLESLLTDAESRALFAAIADKRSAYLAARDAALKEKAAGNVLGAKKFVDEDMKPRLDAYLESLHD
LARYQKQAIDATAGNIHRQYESGRMLLIGLSIVALMMGIGFAFWITRSITRPMNQAVKVAQTVAAGDLTSRIEVEGKDET
GRLLQALKDMNDSLVKIVGQVRLGTDAIATASSEIATGNLDLSSRTEEQASSLEETASSMEQLTSTVKQNADHARQANQM
AVSASEVAVKGGAVVAQVVDTMGSINESSRKIVDIIAVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAQR
SAGAAKEIKTLIGDSVEKADIGSKLVGQAGATMDEIVASVKRVTDIMGEITAASQEQSAGIEQVNQAIAQMDEVTQQNAA
LVEEAAAAASSMQDQAANLAEAVSVFRLAGVNTQRPEQLTSNERIAALPARTHTAAAPVVRTKKLAAIQGSSGGEWEEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=569, Percent_Identity=46.7486818980668, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI1787690, Length=401, Percent_Identity=51.3715710723192, Blast_Score=348, Evalue=4e-97,
Organism=Escherichia coli, GI1788195, Length=357, Percent_Identity=55.7422969187675, Blast_Score=336, Evalue=2e-93,
Organism=Escherichia coli, GI1788194, Length=341, Percent_Identity=54.5454545454545, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1789453, Length=320, Percent_Identity=39.0625, Blast_Score=212, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 58997; Mature: 58997

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGARLGLGFASVLLLLVVVAVIGVWRLQTVGMMTDSLVKNEMHKARIINEWESIINAN
CCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVRALAAAKTNNPETEKFFVDASAAASKGGIALQKQLESLLTDAESRALFAAIADKRSAY
HHHHHHHHCCCCCCCCEEEEECHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LAARDAALKEKAAGNVLGAKKFVDEDMKPRLDAYLESLHDLARYQKQAIDATAGNIHRQY
HHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESGRMLLIGLSIVALMMGIGFAFWITRSITRPMNQAVKVAQTVAAGDLTSRIEVEGKDET
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHH
GRLLQALKDMNDSLVKIVGQVRLGTDAIATASSEIATGNLDLSSRTEEQASSLEETASSM
HHHHHHHHHCHHHHHHHHHHHHCCCHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHH
EQLTSTVKQNADHARQANQMAVSASEVAVKGGAVVAQVVDTMGSINESSRKIVDIIAVID
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAQRSAGAAKEIKTLIGDSVEKAD
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHH
IGSKLVGQAGATMDEIVASVKRVTDIMGEITAASQEQSAGIEQVNQAIAQMDEVTQQNAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHH
LVEEAAAAASSMQDQAANLAEAVSVFRLAGVNTQRPEQLTSNERIAALPARTHTAAAPVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEECCCCCCHHHCCHH
RTKKLAAIQGSSGGEWEEF
HHHHHHEEECCCCCCCCCC
>Mature Secondary Structure
MKIGARLGLGFASVLLLLVVVAVIGVWRLQTVGMMTDSLVKNEMHKARIINEWESIINAN
CCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVRALAAAKTNNPETEKFFVDASAAASKGGIALQKQLESLLTDAESRALFAAIADKRSAY
HHHHHHHHCCCCCCCCEEEEECHHHCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
LAARDAALKEKAAGNVLGAKKFVDEDMKPRLDAYLESLHDLARYQKQAIDATAGNIHRQY
HHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESGRMLLIGLSIVALMMGIGFAFWITRSITRPMNQAVKVAQTVAAGDLTSRIEVEGKDET
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHH
GRLLQALKDMNDSLVKIVGQVRLGTDAIATASSEIATGNLDLSSRTEEQASSLEETASSM
HHHHHHHHHCHHHHHHHHHHHHCCCHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHH
EQLTSTVKQNADHARQANQMAVSASEVAVKGGAVVAQVVDTMGSINESSRKIVDIIAVID
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAQRSAGAAKEIKTLIGDSVEKAD
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHH
IGSKLVGQAGATMDEIVASVKRVTDIMGEITAASQEQSAGIEQVNQAIAQMDEVTQQNAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHH
LVEEAAAAASSMQDQAANLAEAVSVFRLAGVNTQRPEQLTSNERIAALPARTHTAAAPVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEECCCCCCHHHCCHH
RTKKLAAIQGSSGGEWEEF
HHHHHHEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]