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The map label for this gene is namA [H]

Identifier: 74317595

GI number: 74317595

Start: 1660617

End: 1661729

Strand: Direct

Name: namA [H]

Synonym: Tbd_1577

Alternate gene names: 74317595

Gene position: 1660617-1661729 (Clockwise)

Preceding gene: 74317590

Following gene: 74317596

Centisome position: 57.07

GC content: 71.07

Gene sequence:

>1113_bases
GTGAGCACACTGTTTTCGCCCTTCCGACTCGGCACGCGCGTGCTGAAGAACCGCATCGTCGTCTCGCCGATGTGCCAATA
CTCGGCCGAGGACGGCTGCGCGACCGACTGGCACATGATCCATCTGGGCCATCTCGCACTGTCCGGCGCGGGGCTGCTGT
TCGTCGAGGCGACGGCGGTCTCGCCCGAAGGCCGCATCGCGGCGTCCGATCTCGGCCTGTGGTCGGACGACAACGAGGCG
GCGCTGCGCCGCGTCGTCGACGCGATCCGCCGCTACGCGCCACCGCTGGCACTCGGCATCCAGCTCGCCCACGCGGGTCG
CAAGGCGTCGACCGACGTGCCCTGGGCGGGCGGACACTTCATCCTGCCCGAACAGGGCGGCTGGCAGACGCTCGCGCCGT
CCGCCCTCGCCTACGCGCCCGGCGACGCTGCCCCCCGCGCGCTCGACACAGCAGGCCTCGAGCGGGTACGCGGAGAATTC
GTCACCGCCGCCCAGCGCGCCGAGCGACTCGGTTTCGACGTGATCGAACTGCACGCGGCGCACGGTTACCTGCTGCATGA
ATTCCTCTCGCCGCTGTCGAACGTGCGCGACGACCGTTACGGCGGCAGCCTCGAAAACCGCATGCGCTTCCCGCTCGAGG
TGTTCGACGCCATGCGCGCGGCGCTTCACGCAGACGTCCCGCTCGGCGTGCGGATTTCCGCCACCGACTGGGTCGAAGGC
GGCTGGGACATCGCGCAAAGCCTCGCCTTCGCCGAAGCGTTGCGGCGCCGCGGCTGCGCCTTCATCGACGTTTCGAGCGG
CGGCCTGTCGCCGGCGCAGCAGATCCCGGTCGCGCCGGGTTACCAGCTGCCTTTCGCGGCGCAGATCCGCGGCGAGACCG
GCATGCCGACCATGGCCGTCGGCCTGATCACCGACCCTCACCAGGCCGAGAACATCGTCGCCGGCGGCCACGCCGACCTG
GTCGCGCTCGCCCGCGGCATGCTGTACGACCCGCGCTGGCCGTGGCACGCGGCGGCCGAACTCGGCGCGCGCGCCGACGC
GCCCAAGCAATACTGGGCGGCGCCGCCGCACGGACACGGAACCCTGTTCAAGCGTGACAAGGACGCCGAATGA

Upstream 100 bases:

>100_bases
ACCCGGCGACCGACCGCCGCGCAAGCGAGTGCGCGCCGCCGCCGGGTAGCACGACCGTGTAACCCAACCGTTCGAACCCG
TATACAAGGAGGCGCCGCCC

Downstream 100 bases:

>100_bases
CTGCGGTCGGCGAAGCGCCGCAGGGACGCGCGCCGACGCCGGGGCACGGGTGGTCGTTCGAAGCGGGGGTGCCGCGGTGC
TTCCCGGCTTGCCGCGCGCT

Product: putative NADH-dependent flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSTLFSPFRLGTRVLKNRIVVSPMCQYSAEDGCATDWHMIHLGHLALSGAGLLFVEATAVSPEGRIAASDLGLWSDDNEA
ALRRVVDAIRRYAPPLALGIQLAHAGRKASTDVPWAGGHFILPEQGGWQTLAPSALAYAPGDAAPRALDTAGLERVRGEF
VTAAQRAERLGFDVIELHAAHGYLLHEFLSPLSNVRDDRYGGSLENRMRFPLEVFDAMRAALHADVPLGVRISATDWVEG
GWDIAQSLAFAEALRRRGCAFIDVSSGGLSPAQQIPVAPGYQLPFAAQIRGETGMPTMAVGLITDPHQAENIVAGGHADL
VALARGMLYDPRWPWHAAAELGARADAPKQYWAAPPHGHGTLFKRDKDAE

Sequences:

>Translated_370_residues
MSTLFSPFRLGTRVLKNRIVVSPMCQYSAEDGCATDWHMIHLGHLALSGAGLLFVEATAVSPEGRIAASDLGLWSDDNEA
ALRRVVDAIRRYAPPLALGIQLAHAGRKASTDVPWAGGHFILPEQGGWQTLAPSALAYAPGDAAPRALDTAGLERVRGEF
VTAAQRAERLGFDVIELHAAHGYLLHEFLSPLSNVRDDRYGGSLENRMRFPLEVFDAMRAALHADVPLGVRISATDWVEG
GWDIAQSLAFAEALRRRGCAFIDVSSGGLSPAQQIPVAPGYQLPFAAQIRGETGMPTMAVGLITDPHQAENIVAGGHADL
VALARGMLYDPRWPWHAAAELGARADAPKQYWAAPPHGHGTLFKRDKDAE
>Mature_369_residues
STLFSPFRLGTRVLKNRIVVSPMCQYSAEDGCATDWHMIHLGHLALSGAGLLFVEATAVSPEGRIAASDLGLWSDDNEAA
LRRVVDAIRRYAPPLALGIQLAHAGRKASTDVPWAGGHFILPEQGGWQTLAPSALAYAPGDAAPRALDTAGLERVRGEFV
TAAQRAERLGFDVIELHAAHGYLLHEFLSPLSNVRDDRYGGSLENRMRFPLEVFDAMRAALHADVPLGVRISATDWVEGG
WDIAQSLAFAEALRRRGCAFIDVSSGGLSPAQQIPVAPGYQLPFAAQIRGETGMPTMAVGLITDPHQAENIVAGGHADLV
ALARGMLYDPRWPWHAAAELGARADAPKQYWAAPPHGHGTLFKRDKDAE

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=349, Percent_Identity=30.0859598853868, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1789463, Length=353, Percent_Identity=28.6118980169972, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17564188, Length=203, Percent_Identity=31.5270935960591, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI72001454, Length=173, Percent_Identity=35.2601156069364, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=173, Percent_Identity=32.3699421965318, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559804, Length=202, Percent_Identity=31.1881188118812, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=171, Percent_Identity=32.1637426900585, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17565138, Length=173, Percent_Identity=32.3699421965318, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=280, Percent_Identity=26.7857142857143, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=247, Percent_Identity=27.5303643724696, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=358, Percent_Identity=25.9776536312849, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39825; Mature: 39693

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLFSPFRLGTRVLKNRIVVSPMCQYSAEDGCATDWHMIHLGHLALSGAGLLFVEATAV
CCCCCCHHHHHHHHHHCCCEECHHHHCCCCCCCCCCEEEEEEHHHHHCCCCEEEEEEEEE
SPEGRIAASDLGLWSDDNEAALRRVVDAIRRYAPPLALGIQLAHAGRKASTDVPWAGGHF
CCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCEE
ILPEQGGWQTLAPSALAYAPGDAAPRALDTAGLERVRGEFVTAAQRAERLGFDVIELHAA
ECCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHH
HGYLLHEFLSPLSNVRDDRYGGSLENRMRFPLEVFDAMRAALHADVPLGVRISATDWVEG
HHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCC
GWDIAQSLAFAEALRRRGCAFIDVSSGGLSPAQQIPVAPGYQLPFAAQIRGETGMPTMAV
CHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCEEEE
GLITDPHQAENIVAGGHADLVALARGMLYDPRWPWHAAAELGARADAPKQYWAAPPHGHG
EEECCCHHHCCEECCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHCCCCCCCCC
TLFKRDKDAE
CCCCCCCCCC
>Mature Secondary Structure 
STLFSPFRLGTRVLKNRIVVSPMCQYSAEDGCATDWHMIHLGHLALSGAGLLFVEATAV
CCCCCHHHHHHHHHHCCCEECHHHHCCCCCCCCCCEEEEEEHHHHHCCCCEEEEEEEEE
SPEGRIAASDLGLWSDDNEAALRRVVDAIRRYAPPLALGIQLAHAGRKASTDVPWAGGHF
CCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCEE
ILPEQGGWQTLAPSALAYAPGDAAPRALDTAGLERVRGEFVTAAQRAERLGFDVIELHAA
ECCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHH
HGYLLHEFLSPLSNVRDDRYGGSLENRMRFPLEVFDAMRAALHADVPLGVRISATDWVEG
HHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCC
GWDIAQSLAFAEALRRRGCAFIDVSSGGLSPAQQIPVAPGYQLPFAAQIRGETGMPTMAV
CHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCEEEE
GLITDPHQAENIVAGGHADLVALARGMLYDPRWPWHAAAELGARADAPKQYWAAPPHGHG
EEECCCHHHCCEECCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHCCCCCCCCC
TLFKRDKDAE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA