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The map label for this gene is ycfH [C]

Identifier: 74317558

GI number: 74317558

Start: 1625583

End: 1626371

Strand: Reverse

Name: ycfH [C]

Synonym: Tbd_1540

Alternate gene names: 74317558

Gene position: 1626371-1625583 (Counterclockwise)

Preceding gene: 74317559

Following gene: 74317554

Centisome position: 55.89

GC content: 66.16

Gene sequence:

>789_bases
GTGCTCACCCACCGCATGTACATCGACTCGCACTGCCACATCAATTTTCCCGAGCTCGCCGGCAGGCTGCCCGAGGTGTT
CGACCTGATGGCACAGAACGCCGTGAGCCATGCCTTGTGCATCGGCGTCGAGCTCGAGAAATTCCCGAAAATACTGGCCC
TCGCCGAGGCGCATCCGAACGTCTACGCCTCGGTCGGCGTGCACCCGGATCACGAGGACTGCACCGAGCCGAGCGTCGAG
GGACTCGTCGCGCTCGCCGACCACGCCAAGGTCGTCGCAATCGGCGAGACCGGACTCGACTATTTTCGCCTGACCGGCGA
TCTCGAGTGGCAGCGTGAACGCTTCCGCACCCATATCCGGGCCGCACGTCAGTGTCGCAAACCCCTCGTGATCCACACGC
GTTCCGCGGCCGACGACACCCTGCAGATCATGCGCGAGGAAAACGCGGGGGAGGCGGGTGGCGTGATGCACTGCTTTACC
GAGAGCCTCGCGGTTGCGGAAGCGGCGGTCGATCTCGGCTTCTACATCTCGTTCTCGGGCATCGTCACGTTCAAGAACGC
GGCCGCGCTGCGCGAGGTGGCCGCCGCGATCCCGCTCGAGCGCATGCTGATCGAGACCGATTCGCCCTATCTCGCGCCGG
TGCCGCATCGCGGCAAGACCAACGAGCCCGGCTTCGTCAAGCACGTCGCCGAGGAAATCGCGCGCGTGCGCGGTATCCCG
GTCGAGGCCGTCGGCGCGGCGACCAGCGAGAACTTCTTCCGGCTGTTCGCTTCGGCGCGGCCGGCCTGA

Upstream 100 bases:

>100_bases
CAACGAAAGCGGCAAGGCGGCGCAGAACAAGATTGAAGGTTTGCTCGGCGGTTCGTTAAAATCGGTGCGTCCCACCCACA
CCATGTAGCGCCGACCCGCG

Downstream 100 bases:

>100_bases
GCCGCCCCGGCGCGGCACCTAGGTTCCGAAGAAGGATTTCACCTTGTCCATGAAGGACTGGGCGCGCGGGTTGTTGTTGC
GTCCCGGGCTCAGCGCCTCG

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MLTHRMYIDSHCHINFPELAGRLPEVFDLMAQNAVSHALCIGVELEKFPKILALAEAHPNVYASVGVHPDHEDCTEPSVE
GLVALADHAKVVAIGETGLDYFRLTGDLEWQRERFRTHIRAARQCRKPLVIHTRSAADDTLQIMREENAGEAGGVMHCFT
ESLAVAEAAVDLGFYISFSGIVTFKNAAALREVAAAIPLERMLIETDSPYLAPVPHRGKTNEPGFVKHVAEEIARVRGIP
VEAVGAATSENFFRLFASARPA

Sequences:

>Translated_262_residues
MLTHRMYIDSHCHINFPELAGRLPEVFDLMAQNAVSHALCIGVELEKFPKILALAEAHPNVYASVGVHPDHEDCTEPSVE
GLVALADHAKVVAIGETGLDYFRLTGDLEWQRERFRTHIRAARQCRKPLVIHTRSAADDTLQIMREENAGEAGGVMHCFT
ESLAVAEAAVDLGFYISFSGIVTFKNAAALREVAAAIPLERMLIETDSPYLAPVPHRGKTNEPGFVKHVAEEIARVRGIP
VEAVGAATSENFFRLFASARPA
>Mature_262_residues
MLTHRMYIDSHCHINFPELAGRLPEVFDLMAQNAVSHALCIGVELEKFPKILALAEAHPNVYASVGVHPDHEDCTEPSVE
GLVALADHAKVVAIGETGLDYFRLTGDLEWQRERFRTHIRAARQCRKPLVIHTRSAADDTLQIMREENAGEAGGVMHCFT
ESLAVAEAAVDLGFYISFSGIVTFKNAAALREVAAAIPLERMLIETDSPYLAPVPHRGKTNEPGFVKHVAEEIARVRGIP
VEAVGAATSENFFRLFASARPA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=204, Percent_Identity=35.7843137254902, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=29.2134831460674, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=29.2134831460674, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=29.4117647058824, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=28.2352941176471, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI14042943, Length=196, Percent_Identity=31.6326530612245, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI225903439, Length=177, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI226061595, Length=225, Percent_Identity=27.5555555555556, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787342, Length=253, Percent_Identity=46.6403162055336, Blast_Score=222, Evalue=2e-59,
Organism=Escherichia coli, GI87082439, Length=253, Percent_Identity=32.0158102766798, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI48994985, Length=232, Percent_Identity=32.7586206896552, Blast_Score=113, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17559024, Length=279, Percent_Identity=27.9569892473118, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71980746, Length=268, Percent_Identity=27.6119402985075, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17565396, Length=306, Percent_Identity=28.1045751633987, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=293, Percent_Identity=28.3276450511945, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221330018, Length=278, Percent_Identity=30.5755395683453, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586117, Length=278, Percent_Identity=30.5755395683453, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24648690, Length=256, Percent_Identity=28.125, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28732; Mature: 28732

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTHRMYIDSHCHINFPELAGRLPEVFDLMAQNAVSHALCIGVELEKFPKILALAEAHPN
CCCEEEEECCCCEECCHHHHCCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHCCCC
VYASVGVHPDHEDCTEPSVEGLVALADHAKVVAIGETGLDYFRLTGDLEWQRERFRTHIR
EEEEECCCCCCCCCCCCCHHHHEEEECCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHH
AARQCRKPLVIHTRSAADDTLQIMREENAGEAGGVMHCFTESLAVAEAAVDLGFYISFSG
HHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECC
IVTFKNAAALREVAAAIPLERMLIETDSPYLAPVPHRGKTNEPGFVKHVAEEIARVRGIP
EEEEHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
VEAVGAATSENFFRLFASARPA
HHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLTHRMYIDSHCHINFPELAGRLPEVFDLMAQNAVSHALCIGVELEKFPKILALAEAHPN
CCCEEEEECCCCEECCHHHHCCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHCCCC
VYASVGVHPDHEDCTEPSVEGLVALADHAKVVAIGETGLDYFRLTGDLEWQRERFRTHIR
EEEEECCCCCCCCCCCCCHHHHEEEECCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHH
AARQCRKPLVIHTRSAADDTLQIMREENAGEAGGVMHCFTESLAVAEAAVDLGFYISFSG
HHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECC
IVTFKNAAALREVAAAIPLERMLIETDSPYLAPVPHRGKTNEPGFVKHVAEEIARVRGIP
EEEEHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
VEAVGAATSENFFRLFASARPA
HHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]