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The map label for this gene is 74317531

Identifier: 74317531

GI number: 74317531

Start: 1601616

End: 1602638

Strand: Direct

Name: 74317531

Synonym: Tbd_1513

Alternate gene names: NA

Gene position: 1601616-1602638 (Clockwise)

Preceding gene: 74317529

Following gene: 74317532

Centisome position: 55.04

GC content: 68.33

Gene sequence:

>1023_bases
ATGAACCTAGACGAACTCCAGGCTGTCGCCCGAGCCATTGTCGCCCCGCAGAAAGGCGTGCTCGCAGCGGACGAAAGCGG
GCCCACGATCAAGAAGCGTTTCGACACCATCGCGGTCGAATCGACCGAGAAAAGCCGGCGCCGCTATCGCGAAATTATGT
TCACGGCGGAAAGCATCGAACGCTACATCGGCGGCGTCATTCTGTACGACGAAACCCTGCGCCAGAGCACGCGCGACGGC
ACGCCTTTCCCGCAGCTGCTGGCCGGACGCGGCATCATCCCGGGCATCAAGGTCGACCAGGGCGCGAAGCCGCTCGCCCT
GTGTCCGGGCGAGAAAGTGACCGAGGGCCTCGACGGCCTGCGCGAGCGTCTCGTCGAATACCACGGGCTCGGGGCGCAGT
TCGCCAAGTGGCGCGCGGTCATCGACATCGACGCCCATGACCTCCCCTCCCCGTTCGGCATCCACGCCAACGCCCATGCG
CTCGCACGCTACGCGGCGCTCTGCCAGGAAGTGGGGCTCGTCCCGATCGTCGAGCCCGAAGTGCTGATGGACGGCGCGCA
CGACGTCGAGCGTTGCGAAGCCGTCACGGCTCGCGCGCTGGAGGCTGTCTTCGCCGAACTCGACGCCCACGGCGTGGGCC
TCGAAGGCGTGCTACTCAAGCCCAACATGGTCGTGGCCGGCAAGAAATCCACCCGTCAGGCGGGTGTGCAGGAAGTCGCC
GAAGCGACCCTGCGCTGCCTGCGGCGCCACGTACCCGCGGCGGTGCCCGGGATCGTCTTCCTGTCGGGCGGCCAGAGCGC
CGAGGAAGCGACCGCCCACCTCAGCGCGATGAACGCGATGGGCCCCCATCCTTGGCAGGTCAGTTTCTCTTACGGCCGCG
CCCTGCAGGCGCCGGTCCTTGCGGCGTGGCGCGGACACGAAGCCAACGCCGCCGCGGCCCAGGCCGCGCTACTCGAACGC
GCGCGACTCAACGGCCTCGCGCGCGACGGCGCCTACGGGCCCGAAATGGAAAGCGCAGGATGA

Upstream 100 bases:

>100_bases
GCCGCGCGCAGGTCTTTCGGGAGCGAATTACGGTCTAGAGTTGGAAGGAAAGCGCCGCCCCGTCTCAAGAGCACGCGCTG
TCTACGGAGGCCCGAATGCC

Downstream 100 bases:

>100_bases
GCGCGCCCGCCGGCCCGAGCGGCGGTGTCCGGCACTTGGCGGCCTTCGCAGCGACATTTGCAGCCCTCGCCGTGGCGGAC
GCACAGGCTGCAGGCCCAGG

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MNLDELQAVARAIVAPQKGVLAADESGPTIKKRFDTIAVESTEKSRRRYREIMFTAESIERYIGGVILYDETLRQSTRDG
TPFPQLLAGRGIIPGIKVDQGAKPLALCPGEKVTEGLDGLRERLVEYHGLGAQFAKWRAVIDIDAHDLPSPFGIHANAHA
LARYAALCQEVGLVPIVEPEVLMDGAHDVERCEAVTARALEAVFAELDAHGVGLEGVLLKPNMVVAGKKSTRQAGVQEVA
EATLRCLRRHVPAAVPGIVFLSGGQSAEEATAHLSAMNAMGPHPWQVSFSYGRALQAPVLAAWRGHEANAAAAQAALLER
ARLNGLARDGAYGPEMESAG

Sequences:

>Translated_340_residues
MNLDELQAVARAIVAPQKGVLAADESGPTIKKRFDTIAVESTEKSRRRYREIMFTAESIERYIGGVILYDETLRQSTRDG
TPFPQLLAGRGIIPGIKVDQGAKPLALCPGEKVTEGLDGLRERLVEYHGLGAQFAKWRAVIDIDAHDLPSPFGIHANAHA
LARYAALCQEVGLVPIVEPEVLMDGAHDVERCEAVTARALEAVFAELDAHGVGLEGVLLKPNMVVAGKKSTRQAGVQEVA
EATLRCLRRHVPAAVPGIVFLSGGQSAEEATAHLSAMNAMGPHPWQVSFSYGRALQAPVLAAWRGHEANAAAAQAALLER
ARLNGLARDGAYGPEMESAG
>Mature_340_residues
MNLDELQAVARAIVAPQKGVLAADESGPTIKKRFDTIAVESTEKSRRRYREIMFTAESIERYIGGVILYDETLRQSTRDG
TPFPQLLAGRGIIPGIKVDQGAKPLALCPGEKVTEGLDGLRERLVEYHGLGAQFAKWRAVIDIDAHDLPSPFGIHANAHA
LARYAALCQEVGLVPIVEPEVLMDGAHDVERCEAVTARALEAVFAELDAHGVGLEGVLLKPNMVVAGKKSTRQAGVQEVA
EATLRCLRRHVPAAVPGIVFLSGGQSAEEATAHLSAMNAMGPHPWQVSFSYGRALQAPVLAAWRGHEANAAAAQAALLER
ARLNGLARDGAYGPEMESAG

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI4885063, Length=338, Percent_Identity=51.4792899408284, Blast_Score=333, Evalue=1e-91,
Organism=Homo sapiens, GI34577112, Length=333, Percent_Identity=52.5525525525526, Blast_Score=333, Evalue=1e-91,
Organism=Homo sapiens, GI34577110, Length=333, Percent_Identity=52.5525525525526, Blast_Score=333, Evalue=1e-91,
Organism=Homo sapiens, GI4557305, Length=333, Percent_Identity=52.5525525525526, Blast_Score=333, Evalue=1e-91,
Organism=Homo sapiens, GI193794814, Length=333, Percent_Identity=52.5525525525526, Blast_Score=333, Evalue=1e-91,
Organism=Homo sapiens, GI40354205, Length=330, Percent_Identity=53.3333333333333, Blast_Score=332, Evalue=4e-91,
Organism=Caenorhabditis elegans, GI71983985, Length=330, Percent_Identity=52.7272727272727, Blast_Score=333, Evalue=7e-92,
Organism=Caenorhabditis elegans, GI25150450, Length=332, Percent_Identity=51.5060240963855, Blast_Score=330, Evalue=5e-91,
Organism=Caenorhabditis elegans, GI71983990, Length=231, Percent_Identity=51.5151515151515, Blast_Score=232, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24650282, Length=331, Percent_Identity=53.4743202416918, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24650280, Length=331, Percent_Identity=53.4743202416918, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24650278, Length=331, Percent_Identity=53.4743202416918, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI45553577, Length=333, Percent_Identity=53.1531531531532, Blast_Score=328, Evalue=3e-90,
Organism=Drosophila melanogaster, GI221459619, Length=332, Percent_Identity=53.6144578313253, Blast_Score=328, Evalue=4e-90,
Organism=Drosophila melanogaster, GI24650288, Length=332, Percent_Identity=53.6144578313253, Blast_Score=328, Evalue=4e-90,
Organism=Drosophila melanogaster, GI24650304, Length=331, Percent_Identity=45.9214501510574, Blast_Score=292, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 36356; Mature: 36356

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00158 ALDOLASE_CLASS_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDELQAVARAIVAPQKGVLAADESGPTIKKRFDTIAVESTEKSRRRYREIMFTAESIE
CCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHH
RYIGGVILYDETLRQSTRDGTPFPQLLAGRGIIPGIKVDQGAKPLALCPGEKVTEGLDGL
HHHCCEEEECHHHHHHCCCCCCCHHHHHCCCCCCCCEECCCCCCEEECCCHHHHHHHHHH
RERLVEYHGLGAQFAKWRAVIDIDAHDLPSPFGIHANAHALARYAALCQEVGLVPIVEPE
HHHHHHHHCCCHHHHHCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHH
VLMDGAHDVERCEAVTARALEAVFAELDAHGVGLEGVLLKPNMVVAGKKSTRQAGVQEVA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEECCCHHHHHHHHHHH
EATLRCLRRHVPAAVPGIVFLSGGQSAEEATAHLSAMNAMGPHPWQVSFSYGRALQAPVL
HHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEHHCCHHHCCHH
AAWRGHEANAAAAQAALLERARLNGLARDGAYGPEMESAG
HHHCCCCCHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNLDELQAVARAIVAPQKGVLAADESGPTIKKRFDTIAVESTEKSRRRYREIMFTAESIE
CCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHH
RYIGGVILYDETLRQSTRDGTPFPQLLAGRGIIPGIKVDQGAKPLALCPGEKVTEGLDGL
HHHCCEEEECHHHHHHCCCCCCCHHHHHCCCCCCCCEECCCCCCEEECCCHHHHHHHHHH
RERLVEYHGLGAQFAKWRAVIDIDAHDLPSPFGIHANAHALARYAALCQEVGLVPIVEPE
HHHHHHHHCCCHHHHHCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHH
VLMDGAHDVERCEAVTARALEAVFAELDAHGVGLEGVLLKPNMVVAGKKSTRQAGVQEVA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEECCCHHHHHHHHHHH
EATLRCLRRHVPAAVPGIVFLSGGQSAEEATAHLSAMNAMGPHPWQVSFSYGRALQAPVL
HHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEHHCCHHHCCHH
AAWRGHEANAAAAQAALLERARLNGLARDGAYGPEMESAG
HHHCCCCCHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]