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The map label for this gene is galE [C]

Identifier: 74317489

GI number: 74317489

Start: 1555040

End: 1557532

Strand: Direct

Name: galE [C]

Synonym: Tbd_1471

Alternate gene names: 74317489

Gene position: 1555040-1557532 (Clockwise)

Preceding gene: 74317488

Following gene: 74317490

Centisome position: 53.44

GC content: 68.67

Gene sequence:

>2493_bases
ATGGGCGAGGCGATCAGCAACCCCGCGGACGACGTAGCCGATTCGGCCACGACCAAGCCCCTCGTCCTGCTGACGGGCGC
GACCGGCTTTCTCGGCCGCGCGCTCAGCGCCGCGCTGTCAGCCGCGGGCTATACGCTCGTCTGCCTCGACCGCACGCCCA
AGCAACTCGCCCACGCCGAAAGCCTGCGCTGCGATCTGACTTCGGACGAGAGCGTCGACGCCGCGCTGCGCGAGGTGAAG
CAACGTCATGGCACGCGCATCGCCGCAGTCGTCCATCTGGCCGGTTATTACGACTTCAGCGGCGAGGCCAACCCGCTCTA
TCGCGCGGTCAACGTCGACGGCACGCGCCGCCTGCTGAAGGCGCTGCAGGCATTCGAGGTCGAACAATTCGTCTACGCCT
CGACGATGCTCGTGCACGCGCCGACCACGCCGGGGGTGCCGATCGACGAATCGTCGCCGCTCGCGCCGCGCTGGGCCTAT
CCGCAATCGAAGCTCGAGACCGAAGCCGTCGTCGCCGAGGCGCACGGCGCGATTCCCTACGTGCTGCTGCGCATCGCCGG
CGTCTACACGTCGGCGGTCCAGCCGCCGACGCTGGCCCACCAGATCCGCTGGATCTACGAGCGCAAGCTCGAGGCCCGCC
TCTTCCCCGGCGAGACCTCGCACGGTCAGTCGTTCATCCACATCGATGATCTTTGCGACGCGCTGGTGCGCGTGGTGCAG
CGCCGGACCAGCTTGCCGCCCGACCTCGCGCTGCTGGTCGGCGAGCCCGTTCCGCTGAGCTACGACGCGACGCAAAACCG
GCTCGGCACGCTGATCCACGGCGAACACTGGGAGACCGAGACCCTGCCCAAGCCTTTGGCCAAGGCCGGCGCCATGCTGC
AGCGCACGCTCGAGACCGTCGTTCCCGACTCGGTCGACCGCGGCGAGAAGCCCTTCGTCAAACCCTTCATGGTCGAACTC
GCCGACGACCATTACGAACTCGACGTCTCGCGCGCGCACGCGCTGCTCGGGTGGACGCCGCGCCACAGCCTGCGCGACGA
GCTGCCCGGCATCGTTGCCGCGCTCAAGGCCGATCCACTCGACTGGTACCGCGCCAACAAGATCCCGCCGCCCGAGTGGC
TCGAGACCCTGACCGAGCATCCCGACGACGCGCACGCCTTGCTCGAGAACGCCGAGACGACGGCGCGAGGCCAGCACGCG
CAGTATCTCTGGGCGCATTTTCTCAACATCGGCCTCGGCCTGTGGCTGATGTCGAGCCCGCCGATCCTCGGCTATCCGGA
TCAGGCGATGACGCTGAACGACGTCATCAGCGGCGCGCTCGTCCTCATCTTCGGCACGCTTTCGCTGTCGCGGCACTTCG
CCTGGGCACGGGTCGTCACCGCGAGCGTCGGCGTATGGCTCTTGTTCGCGCCGCTCGTGTTCTGGGCGCCGACGGCCGCG
GGATATCTCAACGACACGCTCGTCGGCGCGCTCGTGATCGGCTTTTCGATGCTGGTCCCGCCGACGCCGGGCGTCGGCGT
CGCGGCGCGGACGACCGGGCCCGATGTGCCGCCCGGATGGGACTACACGCCCTCGGGCTGGACCCAGCGCATTCCGATCA
TCGCGCTCGCCTTCGTCGGCCTCGCGATCTCGCGCTATCTCGCGGCCTACCAGCTCGGCCATACCGAAAGCGCCTGGGAC
CCCTTCTTCGGCGAGGGCACCGAGCGCATCATCACCTCCGAGGTGTCGCAGGCCTGGCCGGTGCCCGACGCCGGCCTCGG
CGCGACGACCTACATGCTCGAAATCCTCACCGGCATCATCGGCGGGCGCGCACGCTGGCGCACCATGCCCTGGCTCGTCG
TCCTGTTCGGCGTCATGATCGTGCCGCTCGGCGCGATCAGCCTGTTCTTCATCATCATCCAGCCCATCGTCATCGGCACC
TGGTGCACGCTGTGCCTCGTCGCCGCCGCGGCCATGCTGCTGCAGATTCCGTATTCGCTCGACGAACTCGTCGCCAGCGG
CCAGTTTCTGCTCGACCGCCGGCGCCAGGGCAAGTCGCTGATCCTCGCTTTTTTCCGCGGCGACACGATGGAAGGCGGTG
CGCGCACGCCCGGCGACGACTTCGAGCGCCCGGCGCGCGAGGTGCTCCGCGACATGCTCGGCGGCGGCGTCAACGCGCCG
TGGACCCTGCTCGCGAGCGCAGCGCTCGGCATCTGGATGATGTGTACGCGGCTCGTCTTCGACACCGCGGGCGCGCAGGC
CGACAGCGACCACCTGCTCGGCGCACTCGTCATCACGGCATCGATCAGCGCGCTCGCCGAAGCCGCACGCCCGCTTCGCT
TCGTCAATGCACTGCTCGGCATCGCGCTGATGTTCGCCCCCTTCATGTTCGACGGCGGCAGTCTCGTCGCCGACGCGGCC
GGCATCCTTGCCGGCCTGTTGCTGATCGCGCTCAGCATGCCGCGCGGTCGTATCGACAACCACTACGGGGCGTGGAGCCG
CTATCTGCTCTGA

Upstream 100 bases:

>100_bases
GTTTCTGCGCGATGCGGAACCGTAGCGCCGGCGCGCGGTCGCTAGCGAAGAACCGCGCGCGTCCGGGCGTGGGTGTGCAG
AACCGTAGAACGGGAGGAGC

Downstream 100 bases:

>100_bases
GCGGCCACGGCCATCACGGGTAAAGCGGCGCGCAGTGACAGGAGGTGCGATGGGTTCCGAGACCGACCACGACAACTTCG
ACGCGGTGATCGTCGGCGCC

Product: hypothetical protein

Products: UDPglucoseal [C]

Alternate protein names: NAD-Dependent Epimerase/Dehydratase; Nucleoside-Diphosphate-Sugar Epimerase; DNA Polymerase 3 Epsilon Subunit; DTDP-Glucose 4 6-Dehydratase; UDP-Glucose Epimerase; Short Chain Dehydrogenase/Reductase Family Oxidoreductase; Steroid Dehydrogenase; Nucleotide-Diphosphate-Sugar Epimerase; Facilitator Superfamily Permease

Number of amino acids: Translated: 830; Mature: 829

Protein sequence:

>830_residues
MGEAISNPADDVADSATTKPLVLLTGATGFLGRALSAALSAAGYTLVCLDRTPKQLAHAESLRCDLTSDESVDAALREVK
QRHGTRIAAVVHLAGYYDFSGEANPLYRAVNVDGTRRLLKALQAFEVEQFVYASTMLVHAPTTPGVPIDESSPLAPRWAY
PQSKLETEAVVAEAHGAIPYVLLRIAGVYTSAVQPPTLAHQIRWIYERKLEARLFPGETSHGQSFIHIDDLCDALVRVVQ
RRTSLPPDLALLVGEPVPLSYDATQNRLGTLIHGEHWETETLPKPLAKAGAMLQRTLETVVPDSVDRGEKPFVKPFMVEL
ADDHYELDVSRAHALLGWTPRHSLRDELPGIVAALKADPLDWYRANKIPPPEWLETLTEHPDDAHALLENAETTARGQHA
QYLWAHFLNIGLGLWLMSSPPILGYPDQAMTLNDVISGALVLIFGTLSLSRHFAWARVVTASVGVWLLFAPLVFWAPTAA
GYLNDTLVGALVIGFSMLVPPTPGVGVAARTTGPDVPPGWDYTPSGWTQRIPIIALAFVGLAISRYLAAYQLGHTESAWD
PFFGEGTERIITSEVSQAWPVPDAGLGATTYMLEILTGIIGGRARWRTMPWLVVLFGVMIVPLGAISLFFIIIQPIVIGT
WCTLCLVAAAAMLLQIPYSLDELVASGQFLLDRRRQGKSLILAFFRGDTMEGGARTPGDDFERPAREVLRDMLGGGVNAP
WTLLASAALGIWMMCTRLVFDTAGAQADSDHLLGALVITASISALAEAARPLRFVNALLGIALMFAPFMFDGGSLVADAA
GILAGLLLIALSMPRGRIDNHYGAWSRYLL

Sequences:

>Translated_830_residues
MGEAISNPADDVADSATTKPLVLLTGATGFLGRALSAALSAAGYTLVCLDRTPKQLAHAESLRCDLTSDESVDAALREVK
QRHGTRIAAVVHLAGYYDFSGEANPLYRAVNVDGTRRLLKALQAFEVEQFVYASTMLVHAPTTPGVPIDESSPLAPRWAY
PQSKLETEAVVAEAHGAIPYVLLRIAGVYTSAVQPPTLAHQIRWIYERKLEARLFPGETSHGQSFIHIDDLCDALVRVVQ
RRTSLPPDLALLVGEPVPLSYDATQNRLGTLIHGEHWETETLPKPLAKAGAMLQRTLETVVPDSVDRGEKPFVKPFMVEL
ADDHYELDVSRAHALLGWTPRHSLRDELPGIVAALKADPLDWYRANKIPPPEWLETLTEHPDDAHALLENAETTARGQHA
QYLWAHFLNIGLGLWLMSSPPILGYPDQAMTLNDVISGALVLIFGTLSLSRHFAWARVVTASVGVWLLFAPLVFWAPTAA
GYLNDTLVGALVIGFSMLVPPTPGVGVAARTTGPDVPPGWDYTPSGWTQRIPIIALAFVGLAISRYLAAYQLGHTESAWD
PFFGEGTERIITSEVSQAWPVPDAGLGATTYMLEILTGIIGGRARWRTMPWLVVLFGVMIVPLGAISLFFIIIQPIVIGT
WCTLCLVAAAAMLLQIPYSLDELVASGQFLLDRRRQGKSLILAFFRGDTMEGGARTPGDDFERPAREVLRDMLGGGVNAP
WTLLASAALGIWMMCTRLVFDTAGAQADSDHLLGALVITASISALAEAARPLRFVNALLGIALMFAPFMFDGGSLVADAA
GILAGLLLIALSMPRGRIDNHYGAWSRYLL
>Mature_829_residues
GEAISNPADDVADSATTKPLVLLTGATGFLGRALSAALSAAGYTLVCLDRTPKQLAHAESLRCDLTSDESVDAALREVKQ
RHGTRIAAVVHLAGYYDFSGEANPLYRAVNVDGTRRLLKALQAFEVEQFVYASTMLVHAPTTPGVPIDESSPLAPRWAYP
QSKLETEAVVAEAHGAIPYVLLRIAGVYTSAVQPPTLAHQIRWIYERKLEARLFPGETSHGQSFIHIDDLCDALVRVVQR
RTSLPPDLALLVGEPVPLSYDATQNRLGTLIHGEHWETETLPKPLAKAGAMLQRTLETVVPDSVDRGEKPFVKPFMVELA
DDHYELDVSRAHALLGWTPRHSLRDELPGIVAALKADPLDWYRANKIPPPEWLETLTEHPDDAHALLENAETTARGQHAQ
YLWAHFLNIGLGLWLMSSPPILGYPDQAMTLNDVISGALVLIFGTLSLSRHFAWARVVTASVGVWLLFAPLVFWAPTAAG
YLNDTLVGALVIGFSMLVPPTPGVGVAARTTGPDVPPGWDYTPSGWTQRIPIIALAFVGLAISRYLAAYQLGHTESAWDP
FFGEGTERIITSEVSQAWPVPDAGLGATTYMLEILTGIIGGRARWRTMPWLVVLFGVMIVPLGAISLFFIIIQPIVIGTW
CTLCLVAAAAMLLQIPYSLDELVASGQFLLDRRRQGKSLILAFFRGDTMEGGARTPGDDFERPAREVLRDMLGGGVNAPW
TLLASAALGIWMMCTRLVFDTAGAQADSDHLLGALVITASISALAEAARPLRFVNALLGIALMFAPFMFDGGSLVADAAG
ILAGLLLIALSMPRGRIDNHYGAWSRYLL

Specific function: Galactose metabolism; third step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 89959; Mature: 89828

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEAISNPADDVADSATTKPLVLLTGATGFLGRALSAALSAAGYTLVCLDRTPKQLAHAE
CCCCCCCCHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
SLRCDLTSDESVDAALREVKQRHGTRIAAVVHLAGYYDFSGEANPLYRAVNVDGTRRLLK
HCEECCCCCCHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHH
ALQAFEVEQFVYASTMLVHAPTTPGVPIDESSPLAPRWAYPQSKLETEAVVAEAHGAIPY
HHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
VLLRIAGVYTSAVQPPTLAHQIRWIYERKLEARLFPGETSHGQSFIHIDDLCDALVRVVQ
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEHHHHHHHHHHHHH
RRTSLPPDLALLVGEPVPLSYDATQNRLGTLIHGEHWETETLPKPLAKAGAMLQRTLETV
HHCCCCCCEEHEECCCCCCCCCCHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VPDSVDRGEKPFVKPFMVELADDHYELDVSRAHALLGWTPRHSLRDELPGIVAALKADPL
CCCCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
DWYRANKIPPPEWLETLTEHPDDAHALLENAETTARGQHAQYLWAHFLNIGLGLWLMSSP
HHHHCCCCCCHHHHHHHHCCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHEECCC
PILGYPDQAMTLNDVISGALVLIFGTLSLSRHFAWARVVTASVGVWLLFAPLVFWAPTAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
GYLNDTLVGALVIGFSMLVPPTPGVGVAARTTGPDVPPGWDYTPSGWTQRIPIIALAFVG
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LAISRYLAAYQLGHTESAWDPFFGEGTERIITSEVSQAWPVPDAGLGATTYMLEILTGII
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
GGRARWRTMPWLVVLFGVMIVPLGAISLFFIIIQPIVIGTWCTLCLVAAAAMLLQIPYSL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
DELVASGQFLLDRRRQGKSLILAFFRGDTMEGGARTPGDDFERPAREVLRDMLGGGVNAP
HHHHHCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCH
WTLLASAALGIWMMCTRLVFDTAGAQADSDHLLGALVITASISALAEAARPLRFVNALLG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALMFAPFMFDGGSLVADAAGILAGLLLIALSMPRGRIDNHYGAWSRYLL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure 
GEAISNPADDVADSATTKPLVLLTGATGFLGRALSAALSAAGYTLVCLDRTPKQLAHAE
CCCCCCCHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
SLRCDLTSDESVDAALREVKQRHGTRIAAVVHLAGYYDFSGEANPLYRAVNVDGTRRLLK
HCEECCCCCCHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHH
ALQAFEVEQFVYASTMLVHAPTTPGVPIDESSPLAPRWAYPQSKLETEAVVAEAHGAIPY
HHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
VLLRIAGVYTSAVQPPTLAHQIRWIYERKLEARLFPGETSHGQSFIHIDDLCDALVRVVQ
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEHHHHHHHHHHHHH
RRTSLPPDLALLVGEPVPLSYDATQNRLGTLIHGEHWETETLPKPLAKAGAMLQRTLETV
HHCCCCCCEEHEECCCCCCCCCCHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VPDSVDRGEKPFVKPFMVELADDHYELDVSRAHALLGWTPRHSLRDELPGIVAALKADPL
CCCCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
DWYRANKIPPPEWLETLTEHPDDAHALLENAETTARGQHAQYLWAHFLNIGLGLWLMSSP
HHHHCCCCCCHHHHHHHHCCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHEECCC
PILGYPDQAMTLNDVISGALVLIFGTLSLSRHFAWARVVTASVGVWLLFAPLVFWAPTAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
GYLNDTLVGALVIGFSMLVPPTPGVGVAARTTGPDVPPGWDYTPSGWTQRIPIIALAFVG
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LAISRYLAAYQLGHTESAWDPFFGEGTERIITSEVSQAWPVPDAGLGATTYMLEILTGII
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
GGRARWRTMPWLVVLFGVMIVPLGAISLFFIIIQPIVIGTWCTLCLVAAAAMLLQIPYSL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
DELVASGQFLLDRRRQGKSLILAFFRGDTMEGGARTPGDDFERPAREVLRDMLGGGVNAP
HHHHHCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCH
WTLLASAALGIWMMCTRLVFDTAGAQADSDHLLGALVITASISALAEAARPLRFVNALLG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALMFAPFMFDGGSLVADAAGILAGLLLIALSMPRGRIDNHYGAWSRYLL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA