Click here to switch to the map view.

The map label for this gene is 74317476

Identifier: 74317476

GI number: 74317476

Start: 1543713

End: 1545242

Strand: Direct

Name: 74317476

Synonym: Tbd_1458

Alternate gene names: NA

Gene position: 1543713-1545242 (Clockwise)

Preceding gene: 74317475

Following gene: 74317477

Centisome position: 53.05

GC content: 70.52

Gene sequence:

>1530_bases
ATGACCGCCGCACTCGATACGCCGGCGCCGGGCACGGCGCTGATTCGCGCCCTCCACGATCCGGCCTGCTACGACCATCC
CATCGCGCCGGTCCGCGTGATCGAAACCCACATCTCGTGGGTTTTGCTCACCGGCGACTACGCCTACAAAATCAAGAAAC
CGCTCGACCTCGGTTTCCTCGACTTCAGCACGGTCTCGGCGCGCCTGCATGCGTGCTGTGACGAAGTGCGCCTCAATCGC
CGGCTCACGCCGGACATCTACCTCGACGTCGTCGCGATCAGCGGCACGCCCGCCGATCCGCGCATCAACGGCAGCGGCGA
AGCCTTCGAGTTCGCGGTGAAGATGCGGCAGTTCGACGCCGACGCGACGCTCGACCGGCTCGACGCCGCGGGCCGGCTGA
CCGCCGGGCACGTCGACGCGATCGCGACGACGCTTGCGCGCTTTCATCTCGAAGACGCTGCGCGCGCCGGTGCCGACAGC
GCATGGGGCGAGCCTGAGGGGGTCTGGGCGCCGATGGCGCAGAACTTTGCCCAGCTCGCGCCGCGGCTCACCGACGCGGA
CGAACGGGCGCTGCTCGACCGGCTGCAGGATTGGAGCGAAGCCGAGCATCGGCGTCTCGTGCCACTGCTCGCCGCGCGCA
AACGCGAGGGCTTCGTGCGCGAATGCCACGGCGACCTCCATCTCGGCAACCTCGCCTGGGTCGACGACGGCCTGCTGGCC
TTCGATTGTCTCGAGTTCGACGCGGAACTGCGCTGGATCGACATCCAGTCCGAGATCGCGTTCTGCTACATGGACCTGCT
GCAGCGCGGCCATGCCGAATGGGGGTGGCGCTTCGTCAACCGCTGGCTCGAGGAGACCGGCGACTACGCCGGCCTCGCGC
TGCTGCGCTTCTATGCGGTCTATCGCGCACTCGTGCGTGCCAAGGTCGCCGCCGTCGACGGCGCGCAACACGACGACGCG
GCAGCACACCCCCGGCGGCAGGTGCGAACCCTGCTCGATCTGGCGCAGACGCTCGTCGAATCGCCTGCGCCGCGACTCGA
CATCACCCACGGCCCCTCGGGCGCCGGCAAGACGACCGTCACCGACCGCCTGATGCAGGCACCGGGCGCGATCCGTCTGC
GCTCCGACGTCGAGCGCAAGCGGCTTGCCGGCCTGCCGGCGCTCGCCCGCAGCGGGGCCGGCGTCGGCGAGGCGCTTTAC
GCCGAAGACGCGACGCGCGCGACCTATGCGCGGCTCGCCACGCTCGCCGCCGACCTGCTCGATGGCGGCTGGCCCGTGGT
CGTCGACGCTACCTTCGGCGCGCGCTGGCAGCGCGACCTTTTGCGCACCGTGGCCGAGTCTCGCGGCGTCGCGTTCCGCA
TCCTCGACTTCAAGCTCCCGCCTGCCGTCCTGCGCGAGCGCGTCGAAGCGCGTGCACGCGCGCTCACCGACGCATCCGAA
GCCGACCTCGGCGTGCTGGCCCGCCAACTCGAAAGCGCCGAACCGCTCGCCGCCGACGAGCAGGCGCTGGCCGTGGACGC
GGCGTCCTGA

Upstream 100 bases:

>100_bases
GAGGACGTCTACGTCGCCGTCCGCGACGCCTTCGACGCGGCCAAGCGGCGCCTCGAGGACTACGCGCGCCAGCTGTGAGC
GCGCGCTGCGGCAGGGCGCG

Downstream 100 bases:

>100_bases
GCCGCCGCGGACCGGGCACCCGCTTCTCCACGATTCGAAAATCGCCGGCGCCGGGGCCGGCCTCACATTGGCGATTCGCG
CGGACCGTCTACCATTCGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MTAALDTPAPGTALIRALHDPACYDHPIAPVRVIETHISWVLLTGDYAYKIKKPLDLGFLDFSTVSARLHACCDEVRLNR
RLTPDIYLDVVAISGTPADPRINGSGEAFEFAVKMRQFDADATLDRLDAAGRLTAGHVDAIATTLARFHLEDAARAGADS
AWGEPEGVWAPMAQNFAQLAPRLTDADERALLDRLQDWSEAEHRRLVPLLAARKREGFVRECHGDLHLGNLAWVDDGLLA
FDCLEFDAELRWIDIQSEIAFCYMDLLQRGHAEWGWRFVNRWLEETGDYAGLALLRFYAVYRALVRAKVAAVDGAQHDDA
AAHPRRQVRTLLDLAQTLVESPAPRLDITHGPSGAGKTTVTDRLMQAPGAIRLRSDVERKRLAGLPALARSGAGVGEALY
AEDATRATYARLATLAADLLDGGWPVVVDATFGARWQRDLLRTVAESRGVAFRILDFKLPPAVLRERVEARARALTDASE
ADLGVLARQLESAEPLAADEQALAVDAAS

Sequences:

>Translated_509_residues
MTAALDTPAPGTALIRALHDPACYDHPIAPVRVIETHISWVLLTGDYAYKIKKPLDLGFLDFSTVSARLHACCDEVRLNR
RLTPDIYLDVVAISGTPADPRINGSGEAFEFAVKMRQFDADATLDRLDAAGRLTAGHVDAIATTLARFHLEDAARAGADS
AWGEPEGVWAPMAQNFAQLAPRLTDADERALLDRLQDWSEAEHRRLVPLLAARKREGFVRECHGDLHLGNLAWVDDGLLA
FDCLEFDAELRWIDIQSEIAFCYMDLLQRGHAEWGWRFVNRWLEETGDYAGLALLRFYAVYRALVRAKVAAVDGAQHDDA
AAHPRRQVRTLLDLAQTLVESPAPRLDITHGPSGAGKTTVTDRLMQAPGAIRLRSDVERKRLAGLPALARSGAGVGEALY
AEDATRATYARLATLAADLLDGGWPVVVDATFGARWQRDLLRTVAESRGVAFRILDFKLPPAVLRERVEARARALTDASE
ADLGVLARQLESAEPLAADEQALAVDAAS
>Mature_508_residues
TAALDTPAPGTALIRALHDPACYDHPIAPVRVIETHISWVLLTGDYAYKIKKPLDLGFLDFSTVSARLHACCDEVRLNRR
LTPDIYLDVVAISGTPADPRINGSGEAFEFAVKMRQFDADATLDRLDAAGRLTAGHVDAIATTLARFHLEDAARAGADSA
WGEPEGVWAPMAQNFAQLAPRLTDADERALLDRLQDWSEAEHRRLVPLLAARKREGFVRECHGDLHLGNLAWVDDGLLAF
DCLEFDAELRWIDIQSEIAFCYMDLLQRGHAEWGWRFVNRWLEETGDYAGLALLRFYAVYRALVRAKVAAVDGAQHDDAA
AHPRRQVRTLLDLAQTLVESPAPRLDITHGPSGAGKTTVTDRLMQAPGAIRLRSDVERKRLAGLPALARSGAGVGEALYA
EDATRATYARLATLAADLLDGGWPVVVDATFGARWQRDLLRTVAESRGVAFRILDFKLPPAVLRERVEARARALTDASEA
DLGVLARQLESAEPLAADEQALAVDAAS

Specific function: Some isolated peptides of this protein are able to bind to human U937 monocytoblastic and A549 epithelial cell lines [H]

COG id: COG2187

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR010488 [H]

Pfam domain/function: PF06414 Zeta_toxin [H]

EC number: NA

Molecular weight: Translated: 55740; Mature: 55608

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAALDTPAPGTALIRALHDPACYDHPIAPVRVIETHISWVLLTGDYAYKIKKPLDLGFL
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHEECCCEEEEECCEEEEECCCCCCCCC
DFSTVSARLHACCDEVRLNRRLTPDIYLDVVAISGTPADPRINGSGEAFEFAVKMRQFDA
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCC
DATLDRLDAAGRLTAGHVDAIATTLARFHLEDAARAGADSAWGEPEGVWAPMAQNFAQLA
CHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
PRLTDADERALLDRLQDWSEAEHRRLVPLLAARKREGFVRECHGDLHLGNLAWVDDGLLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEECCEEEECCCCHH
FDCLEFDAELRWIDIQSEIAFCYMDLLQRGHAEWGWRFVNRWLEETGDYAGLALLRFYAV
HHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YRALVRAKVAAVDGAQHDDAAAHPRRQVRTLLDLAQTLVESPAPRLDITHGPSGAGKTTV
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHH
TDRLMQAPGAIRLRSDVERKRLAGLPALARSGAGVGEALYAEDATRATYARLATLAADLL
HHHHHHCCCCEEEHHHHHHHHHCCCCHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
DGGWPVVVDATFGARWQRDLLRTVAESRGVAFRILDFKLPPAVLRERVEARARALTDASE
CCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCH
ADLGVLARQLESAEPLAADEQALAVDAAS
HHHHHHHHHHHCCCCCCCCCCHHEEECCC
>Mature Secondary Structure 
TAALDTPAPGTALIRALHDPACYDHPIAPVRVIETHISWVLLTGDYAYKIKKPLDLGFL
CCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHEECCCEEEEECCEEEEECCCCCCCCC
DFSTVSARLHACCDEVRLNRRLTPDIYLDVVAISGTPADPRINGSGEAFEFAVKMRQFDA
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCC
DATLDRLDAAGRLTAGHVDAIATTLARFHLEDAARAGADSAWGEPEGVWAPMAQNFAQLA
CHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
PRLTDADERALLDRLQDWSEAEHRRLVPLLAARKREGFVRECHGDLHLGNLAWVDDGLLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEECCEEEECCCCHH
FDCLEFDAELRWIDIQSEIAFCYMDLLQRGHAEWGWRFVNRWLEETGDYAGLALLRFYAV
HHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YRALVRAKVAAVDGAQHDDAAAHPRRQVRTLLDLAQTLVESPAPRLDITHGPSGAGKTTV
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHH
TDRLMQAPGAIRLRSDVERKRLAGLPALARSGAGVGEALYAEDATRATYARLATLAADLL
HHHHHHCCCCEEEHHHHHHHHHCCCCHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
DGGWPVVVDATFGARWQRDLLRTVAESRGVAFRILDFKLPPAVLRERVEARARALTDASE
CCCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCH
ADLGVLARQLESAEPLAADEQALAVDAAS
HHHHHHHHHHHCCCCCCCCCCHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]