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The map label for this gene is hypE [H]

Identifier: 74317404

GI number: 74317404

Start: 1465633

End: 1466640

Strand: Direct

Name: hypE [H]

Synonym: Tbd_1386

Alternate gene names: 74317404

Gene position: 1465633-1466640 (Clockwise)

Preceding gene: 74317403

Following gene: 74317407

Centisome position: 50.37

GC content: 69.25

Gene sequence:

>1008_bases
ATGAACGAAGAGACCGCTCGCATCCTCCTCGCACACGGCAACGGGGGGCGCCTCATGCGCGAGCTGATCGCCGGCATATT
CGCGCGCCACCTCGGCAATCCGCTGCTCGATACCGATGCCGACGCCGTCGCGCTGCCGCGGCTCGACGGCGAGATCATGG
TCACGACCGACGGGTTCACCGTGCAGCCGCTCGAATTTCCGGGCGGCGATCTCGGCTCGCTGGCCGTGCACGGCGTCGTC
AACGACCTCGCGGTCGCCGGTGCCGAGCCGCGCTACCTGACTCTGTCGGCATTGATCGAGGAAGGACTGGAACTGCCCAC
GCTGGAGCGGCTCATCGCGAGTCTTGCCGACGCTGCGCGCGCCGCCGGCGTCGCAGTCGTCGCGGGCGACACCAAGGTGG
TCAGGCGCGGTGAAGGCGGCGGGCTGTATCTCTCGGTCGCGGGGATCGGCGTGAAACGCGCGGCGACGCTCGATCTGCGG
CGCGTCCAGGCCGGCGACGCGGTGCTCGTGTCGGGGCCGGTCGGCGACCATGGCATCGCGGTCATGCTCGCGCGCGAACA
ATTCGGGCTCTCGGGGGAATTGCGCTCGGACTGTGCGTCGGTGCTTCCGCTTGCCCGGGCGGTGTGGGAGCTGCCCGGTC
TCAGGTTCATGCGCGACCCGACCCGCGGTGGGTTGGCAACCGTTTGCCATGAAATCGCCCGCGCCACCGGGCACACGGTC
GTGCTCACGCAGGCGAGCGTACCTTTGCGGCCCGAAGTCGTGTCGGTGTGCGAAATGCTCGGCTATGACCCTTACTATCT
GGCGTGCGAGGGACGTATCGTCGCCGTGACGGACGCGTCTGCCGCCGGCGAACTGCTCGAGCGTTGGCGCGCCGTGCGGG
GCGGGGAGGACGCCGCGATCATCGGTCGCATCGATGAAGCGGGCGCCCGCGTGATCCTCGAGACCGAGCTCGGCGGGCGC
CGCGTGATCGACGAACTGGAAGACGATCCGTTACCGCGCATCTGCTGA

Upstream 100 bases:

>100_bases
CGGGATTTTCGGTCCGCCTGCCGCAGCGCGTACCGATGAACGACGCCGGCCTGAGCTTCGGCCAGGTCATCGAGTTCCTA
TACCGACAACACACCAAGAC

Downstream 100 bases:

>100_bases
ACGCCCGGACATATGCAAACGTACGTGCCCACTCCCGCCGTTCAGGCGGCGACGTGGTTGCGGCGGTCTCCCGGTCCGGT
GCGACGTTCGTGCCCGGCCG

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNEETARILLAHGNGGRLMRELIAGIFARHLGNPLLDTDADAVALPRLDGEIMVTTDGFTVQPLEFPGGDLGSLAVHGVV
NDLAVAGAEPRYLTLSALIEEGLELPTLERLIASLADAARAAGVAVVAGDTKVVRRGEGGGLYLSVAGIGVKRAATLDLR
RVQAGDAVLVSGPVGDHGIAVMLAREQFGLSGELRSDCASVLPLARAVWELPGLRFMRDPTRGGLATVCHEIARATGHTV
VLTQASVPLRPEVVSVCEMLGYDPYYLACEGRIVAVTDASAAGELLERWRAVRGGEDAAIIGRIDEAGARVILETELGGR
RVIDELEDDPLPRIC

Sequences:

>Translated_335_residues
MNEETARILLAHGNGGRLMRELIAGIFARHLGNPLLDTDADAVALPRLDGEIMVTTDGFTVQPLEFPGGDLGSLAVHGVV
NDLAVAGAEPRYLTLSALIEEGLELPTLERLIASLADAARAAGVAVVAGDTKVVRRGEGGGLYLSVAGIGVKRAATLDLR
RVQAGDAVLVSGPVGDHGIAVMLAREQFGLSGELRSDCASVLPLARAVWELPGLRFMRDPTRGGLATVCHEIARATGHTV
VLTQASVPLRPEVVSVCEMLGYDPYYLACEGRIVAVTDASAAGELLERWRAVRGGEDAAIIGRIDEAGARVILETELGGR
RVIDELEDDPLPRIC
>Mature_335_residues
MNEETARILLAHGNGGRLMRELIAGIFARHLGNPLLDTDADAVALPRLDGEIMVTTDGFTVQPLEFPGGDLGSLAVHGVV
NDLAVAGAEPRYLTLSALIEEGLELPTLERLIASLADAARAAGVAVVAGDTKVVRRGEGGGLYLSVAGIGVKRAATLDLR
RVQAGDAVLVSGPVGDHGIAVMLAREQFGLSGELRSDCASVLPLARAVWELPGLRFMRDPTRGGLATVCHEIARATGHTV
VLTQASVPLRPEVVSVCEMLGYDPYYLACEGRIVAVTDASAAGELLERWRAVRGGEDAAIIGRIDEAGARVILETELGGR
RVIDELEDDPLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=336, Percent_Identity=42.8571428571429, Blast_Score=254, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35256; Mature: 35256

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEETARILLAHGNGGRLMRELIAGIFARHLGNPLLDTDADAVALPRLDGEIMVTTDGFT
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEECCCE
VQPLEFPGGDLGSLAVHGVVNDLAVAGAEPRYLTLSALIEEGLELPTLERLIASLADAAR
EEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHCCCCCCHHHHHHHHHHHHHH
AAGVAVVAGDTKVVRRGEGGGLYLSVAGIGVKRAATLDLRRVQAGDAVLVSGPVGDHGIA
HCCEEEEECCCEEEEECCCCEEEEEEECCCCCHHHHHHHEEECCCCEEEEECCCCCCCEE
VMLAREQFGLSGELRSDCASVLPLARAVWELPGLRFMRDPTRGGLATVCHEIARATGHTV
EEEEEHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHCCCCEE
VLTQASVPLRPEVVSVCEMLGYDPYYLACEGRIVAVTDASAAGELLERWRAVRGGEDAAI
EEEECCCCCCHHHHHHHHHHCCCCEEEEECCEEEEEECCHHHHHHHHHHHHHCCCCCEEE
IGRIDEAGARVILETELGGRRVIDELEDDPLPRIC
EEEECCCCCEEEEEECCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNEETARILLAHGNGGRLMRELIAGIFARHLGNPLLDTDADAVALPRLDGEIMVTTDGFT
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEECCCE
VQPLEFPGGDLGSLAVHGVVNDLAVAGAEPRYLTLSALIEEGLELPTLERLIASLADAAR
EEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHCCCCCCHHHHHHHHHHHHHH
AAGVAVVAGDTKVVRRGEGGGLYLSVAGIGVKRAATLDLRRVQAGDAVLVSGPVGDHGIA
HCCEEEEECCCEEEEECCCCEEEEEEECCCCCHHHHHHHEEECCCCEEEEECCCCCCCEE
VMLAREQFGLSGELRSDCASVLPLARAVWELPGLRFMRDPTRGGLATVCHEIARATGHTV
EEEEEHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHCCCCEE
VLTQASVPLRPEVVSVCEMLGYDPYYLACEGRIVAVTDASAAGELLERWRAVRGGEDAAI
EEEECCCCCCHHHHHHHHHHCCCCEEEEECCEEEEEECCHHHHHHHHHHHHHCCCCCEEE
IGRIDEAGARVILETELGGRRVIDELEDDPLPRIC
EEEECCCCCEEEEEECCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8510650; 7906310; 12597275 [H]