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The map label for this gene is uvrY [H]

Identifier: 74317308

GI number: 74317308

Start: 1360804

End: 1361433

Strand: Direct

Name: uvrY [H]

Synonym: Tbd_1290

Alternate gene names: 74317308

Gene position: 1360804-1361433 (Clockwise)

Preceding gene: 74317307

Following gene: 74317309

Centisome position: 46.77

GC content: 62.38

Gene sequence:

>630_bases
ATGATCCGAGTGCTGATCGCAGACGACCATGCCGTCGTCCGCCAGGGCCTGCGGCACGTGCTGTCCGCCTCGCCCGACAT
CGTCGTCGCCGCCGAGGCGGCGGACGGATTCGAGGTGCTCGAGAAGATCCGCAAGGAGGCCTTCGATCTTGTCTGCCTCG
ACCTGTCGATGCCGAATCTGAGCGGTATCGACCTGATCAAGCGGATTAGGCTCGACTGCACGACCTTGCCGATCCTCGTC
CTCAGCATGCACAACGAGGCGCAGTTCGCGGCACGCGCGCTGAAGGCAGGCGCGGCCGGCTATCTGACCAAGGACAGCGA
CCCCGAAACGCTGATCGGGGCGATCCGCAAGGTCGCCTCGGGCCGGAAGTTCATCGACCCGACGCTGGTCGACGAATTGA
TCTTCGAAAAAATCCTGACCGACGAGCGCGCGCCGCACGAGCAACTGTCCGATCGCGAATTTCAGATCGTCCGGCTGATC
GCGCAGGGCGAATCGCTGAACCAGATCGCCGACAAGCTCTCGCTCAGCGCCAAGACGATCAGCACCTACAAGGCGCGAAG
CATGCAGAAGCTGGGTATTTCGAACCATACCGAGCTCGTGCGCTACGCCATCGCCCACCATTGGATATGA

Upstream 100 bases:

>100_bases
TCATCCTCGGCGGAACGATGACGATAAAAAGCGCACCGGGGCAGGGGGCGGAACTCGCGGTCTGCATCCCGGCCGCGGAC
CCGGCAAGCGGAGGGGTGCA

Downstream 100 bases:

>100_bases
TCGCGCGCCGTCACTTCTGCGCTCGCGCGTAGGGATTCCCTTACAGACAGACGGGCCGCTTCGCCGCCTGCGAATCGGCC
CGCGAGCCCAGGCCGGGCGC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIRVLIADDHAVVRQGLRHVLSASPDIVVAAEAADGFEVLEKIRKEAFDLVCLDLSMPNLSGIDLIKRIRLDCTTLPILV
LSMHNEAQFAARALKAGAAGYLTKDSDPETLIGAIRKVASGRKFIDPTLVDELIFEKILTDERAPHEQLSDREFQIVRLI
AQGESLNQIADKLSLSAKTISTYKARSMQKLGISNHTELVRYAIAHHWI

Sequences:

>Translated_209_residues
MIRVLIADDHAVVRQGLRHVLSASPDIVVAAEAADGFEVLEKIRKEAFDLVCLDLSMPNLSGIDLIKRIRLDCTTLPILV
LSMHNEAQFAARALKAGAAGYLTKDSDPETLIGAIRKVASGRKFIDPTLVDELIFEKILTDERAPHEQLSDREFQIVRLI
AQGESLNQIADKLSLSAKTISTYKARSMQKLGISNHTELVRYAIAHHWI
>Mature_209_residues
MIRVLIADDHAVVRQGLRHVLSASPDIVVAAEAADGFEVLEKIRKEAFDLVCLDLSMPNLSGIDLIKRIRLDCTTLPILV
LSMHNEAQFAARALKAGAAGYLTKDSDPETLIGAIRKVASGRKFIDPTLVDELIFEKILTDERAPHEQLSDREFQIVRLI
AQGESLNQIADKLSLSAKTISTYKARSMQKLGISNHTELVRYAIAHHWI

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=36.231884057971, Blast_Score=153, Evalue=9e-39,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=34.8258706467662, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788521, Length=192, Percent_Identity=34.375, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=30.5825242718447, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=34.2391304347826, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=34.3137254901961, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788712, Length=202, Percent_Identity=28.2178217821782, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786599, Length=218, Percent_Identity=24.3119266055046, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=30.2521008403361, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23176; Mature: 23176

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVLIADDHAVVRQGLRHVLSASPDIVVAAEAADGFEVLEKIRKEAFDLVCLDLSMPNL
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCC
SGIDLIKRIRLDCTTLPILVLSMHNEAQFAARALKAGAAGYLTKDSDPETLIGAIRKVAS
CHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GRKFIDPTLVDELIFEKILTDERAPHEQLSDREFQIVRLIAQGESLNQIADKLSLSAKTI
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
STYKARSMQKLGISNHTELVRYAIAHHWI
HHHHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRVLIADDHAVVRQGLRHVLSASPDIVVAAEAADGFEVLEKIRKEAFDLVCLDLSMPNL
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCC
SGIDLIKRIRLDCTTLPILVLSMHNEAQFAARALKAGAAGYLTKDSDPETLIGAIRKVAS
CHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GRKFIDPTLVDELIFEKILTDERAPHEQLSDREFQIVRLIAQGESLNQIADKLSLSAKTI
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
STYKARSMQKLGISNHTELVRYAIAHHWI
HHHHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]