Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 74317283

GI number: 74317283

Start: 1326515

End: 1328791

Strand: Direct

Name: yciR [C]

Synonym: Tbd_1265

Alternate gene names: 74317283

Gene position: 1326515-1328791 (Clockwise)

Preceding gene: 74317281

Following gene: 74317284

Centisome position: 45.59

GC content: 67.33

Gene sequence:

>2277_bases
ATGGTGTACCGAATCTTGCTGCAGGTGTGGCTGGGCTGCGTCTTCCTGCTTGCTCCGGAGTCGGACGCGCACGCCCAGCC
GGTCCGCGTCGGCGTTTTCGAAAATCCGCCCATCGTTTCCGCCGGCCTTGACGGCATGCCGCGCGGCATCTCGATCGACG
TCATTCAACTCGTCGCCCAGCGCGAAGGCTGGCAGGTCAGCTATGTGAGCTCGCCGGTCGACGATCTCATCGGTCGCCTC
GAACGCGGCGAGATCGACGTGCTCGCTGCCATTGGCTACAGCGAGGAATACGCGCGCAGACTACGCCTGAGCCGCGAGAG
CCTGATTGCGAACTGGGCCATGATTTTCCGGCGCGCCGACGTCGCGATCGATTCCCTCCCGCAACTCAAGCGCCGGCGCG
TGGCGCTCGTCCGCGGCAGCGTGCAGGCGAAGGCCCTGATCAGGCTGGCGGAGCAGTTCGACGCGCCGTTCAAGCCGGTC
TATGTCGACGACTTTCCGGCAGTCGTGCGTGCGCTGCAGGAACGCCGCGCCGACGCCGGCTCGGTCAATCGGCTGTTCGC
GGTCGAGTACGCGAACCAGCCCGGTGTGGTCGAGACGGCTATCGTCTTCAGCCCGGTTTCGGTGCATTACGCTGCGCCGA
GAAGCGCCGATCCCGCGCTGCTCGACGCCCTCGACCGTCATCTCGCGGAACTCAAGGCCGACACCGATTCGGTCTATTAC
ACATCGCTCAAGCGCTGGCTTGCCGCCGCGCCGGACGGGCGTCTGCCTCCCTGGTTGCCCTGGCTGATCGGCGGCGGCGG
CGGCGCGCTGCTGCTCGCGCTCGCCTTCGTCGTCCTGCTTCGCCACAAGGTCGGGCGTCAGACTGGCGAATTGCAGCGTC
GTGCCGACCAGCTCGAACTCGAGGTCGAACAGCGCGAGCAGGCGCAGCGCCATCTCAACCGGCTCGCCTATTTCGATGGC
CTGACGCGGCTGCCCAATCGCGAGGCCTTCCGACTGACCCTGAGCCAGGCGCTGCGCACGCTGAATGGCAGTGGCGGGCG
TCTGGCCCTGCTTTTCGTCGACGTCGACCGCCTGAAAAACGTCAACGACGGCCTTGGCCACCGTGCCGGCGACATGCTGC
TGCAGCAGATCGCAGGCCGTCTCCAGTCGGTTTTACGCGGCCACGACCACCTGAGCCGCTTCGGCGGCGACGAGTTCGTC
GTCATCGTCTCCGAGATCGTCCGCGACACGGACGCCGAGCGGGTGGCTGGCCGCCTGCTCGCCGCCCTCGCGGCGCCGGT
CGACATCGGCGGCACCCAGGTCTACACCGGCGCGAGCATCGGCATCGCGCTCTACCCCGAGGACGCCGAGTCGCTCGACG
GCCTGCTCAAGCACGCCGACACCGCGATGTACCAAGCCAAGGAGCAGGGCGGCAATCGCTATGTCTTCTATCACGCCCAG
CAGACAGAACGGGCCGTCGAGCGGCTCACGCTGGATACCCGGCTGCGCCAGGCGCTCGAGCGCAACGAACTGGTCCTGCA
TTACCAGCCGATCGTCGAACTGGCGAGCGGACGCATCGTCGGCGGCGAGGCCCTGGTGCGCTGGGAAGACCCCGAGCGCG
GACTGGTCATGCCGTCGGCCTTCATTCCGGCTGCCGAAGACACGGGCTTGATCGTGGCACTCAGCGACTGGGTACTCGAG
GCCTGCTGCACCCAGCTGCGCGCGTGGCAGCAGCAGGGCCGGGCGGCGGACGATCTGACGCTCTCGGTCAACATCTCGAC
GCGCCAGTTCGAGGGCGAGCATCTGACCCGCGCGGTCGACCGGGCGCTCGCGCGCAGCGGCCTGCGTCCGGACTGCCTCG
AACTCGAGATCACCGAGAACGTCATGCTCGTCATGACCGACGAAGTCCGCACTTGTCTGGACGCGCTGCGTGCACGCGGC
GTGCGGCTCGCGCTCGACGATTTCGGCACGGGCTATTCGAGCCTGAGCTATCTGAGCCAGTTGCCTTTTCACGGACTGAA
AATCGACCAGTCCTTCGTGCGCAAGATCCCAGCGCACCCGAGCGAGACGCAGATCGTCACGACGATACTGGCGCTCGCCA
GGGGGCTGGGGATGGAGGTCGTCGCCGAGGGCATCGAAACGGCCCAGCAGTACGCCTTCCTGCGCGATCGCGGCTGCGAG
TTCGGACAGGGAAACCTCATGAGTACCCCGCAGGCGGCGGACGCGTTCGCGTCCCTGCTCGACCGGCAAAAGGCCAGCGG
CCAGCGCCCGGTGCACGGGCACGAAACGGCCCCTTGA

Upstream 100 bases:

>100_bases
GGCAGCCGCGCTGAGGCGCCGACCGCTACCTATACTTGAGCGACGACGGGCACCGATTCGAGCGCGGTTTGGCCGCTTCA
ATCCGAGGACACGGGCTGGC

Downstream 100 bases:

>100_bases
CGGGGGCGCCTAAACCATCGCCGGCGACGCAAGGGGCGTGCGCAGCAGTTCTCTGACCTGTCCGCACACAGGTCGTCAAA
CCACGCCTCCGCGAGGGTCT

Product: periplasmic sensor diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 758; Mature: 758

Protein sequence:

>758_residues
MVYRILLQVWLGCVFLLAPESDAHAQPVRVGVFENPPIVSAGLDGMPRGISIDVIQLVAQREGWQVSYVSSPVDDLIGRL
ERGEIDVLAAIGYSEEYARRLRLSRESLIANWAMIFRRADVAIDSLPQLKRRRVALVRGSVQAKALIRLAEQFDAPFKPV
YVDDFPAVVRALQERRADAGSVNRLFAVEYANQPGVVETAIVFSPVSVHYAAPRSADPALLDALDRHLAELKADTDSVYY
TSLKRWLAAAPDGRLPPWLPWLIGGGGGALLLALAFVVLLRHKVGRQTGELQRRADQLELEVEQREQAQRHLNRLAYFDG
LTRLPNREAFRLTLSQALRTLNGSGGRLALLFVDVDRLKNVNDGLGHRAGDMLLQQIAGRLQSVLRGHDHLSRFGGDEFV
VIVSEIVRDTDAERVAGRLLAALAAPVDIGGTQVYTGASIGIALYPEDAESLDGLLKHADTAMYQAKEQGGNRYVFYHAQ
QTERAVERLTLDTRLRQALERNELVLHYQPIVELASGRIVGGEALVRWEDPERGLVMPSAFIPAAEDTGLIVALSDWVLE
ACCTQLRAWQQQGRAADDLTLSVNISTRQFEGEHLTRAVDRALARSGLRPDCLELEITENVMLVMTDEVRTCLDALRARG
VRLALDDFGTGYSSLSYLSQLPFHGLKIDQSFVRKIPAHPSETQIVTTILALARGLGMEVVAEGIETAQQYAFLRDRGCE
FGQGNLMSTPQAADAFASLLDRQKASGQRPVHGHETAP

Sequences:

>Translated_758_residues
MVYRILLQVWLGCVFLLAPESDAHAQPVRVGVFENPPIVSAGLDGMPRGISIDVIQLVAQREGWQVSYVSSPVDDLIGRL
ERGEIDVLAAIGYSEEYARRLRLSRESLIANWAMIFRRADVAIDSLPQLKRRRVALVRGSVQAKALIRLAEQFDAPFKPV
YVDDFPAVVRALQERRADAGSVNRLFAVEYANQPGVVETAIVFSPVSVHYAAPRSADPALLDALDRHLAELKADTDSVYY
TSLKRWLAAAPDGRLPPWLPWLIGGGGGALLLALAFVVLLRHKVGRQTGELQRRADQLELEVEQREQAQRHLNRLAYFDG
LTRLPNREAFRLTLSQALRTLNGSGGRLALLFVDVDRLKNVNDGLGHRAGDMLLQQIAGRLQSVLRGHDHLSRFGGDEFV
VIVSEIVRDTDAERVAGRLLAALAAPVDIGGTQVYTGASIGIALYPEDAESLDGLLKHADTAMYQAKEQGGNRYVFYHAQ
QTERAVERLTLDTRLRQALERNELVLHYQPIVELASGRIVGGEALVRWEDPERGLVMPSAFIPAAEDTGLIVALSDWVLE
ACCTQLRAWQQQGRAADDLTLSVNISTRQFEGEHLTRAVDRALARSGLRPDCLELEITENVMLVMTDEVRTCLDALRARG
VRLALDDFGTGYSSLSYLSQLPFHGLKIDQSFVRKIPAHPSETQIVTTILALARGLGMEVVAEGIETAQQYAFLRDRGCE
FGQGNLMSTPQAADAFASLLDRQKASGQRPVHGHETAP
>Mature_758_residues
MVYRILLQVWLGCVFLLAPESDAHAQPVRVGVFENPPIVSAGLDGMPRGISIDVIQLVAQREGWQVSYVSSPVDDLIGRL
ERGEIDVLAAIGYSEEYARRLRLSRESLIANWAMIFRRADVAIDSLPQLKRRRVALVRGSVQAKALIRLAEQFDAPFKPV
YVDDFPAVVRALQERRADAGSVNRLFAVEYANQPGVVETAIVFSPVSVHYAAPRSADPALLDALDRHLAELKADTDSVYY
TSLKRWLAAAPDGRLPPWLPWLIGGGGGALLLALAFVVLLRHKVGRQTGELQRRADQLELEVEQREQAQRHLNRLAYFDG
LTRLPNREAFRLTLSQALRTLNGSGGRLALLFVDVDRLKNVNDGLGHRAGDMLLQQIAGRLQSVLRGHDHLSRFGGDEFV
VIVSEIVRDTDAERVAGRLLAALAAPVDIGGTQVYTGASIGIALYPEDAESLDGLLKHADTAMYQAKEQGGNRYVFYHAQ
QTERAVERLTLDTRLRQALERNELVLHYQPIVELASGRIVGGEALVRWEDPERGLVMPSAFIPAAEDTGLIVALSDWVLE
ACCTQLRAWQQQGRAADDLTLSVNISTRQFEGEHLTRAVDRALARSGLRPDCLELEITENVMLVMTDEVRTCLDALRARG
VRLALDDFGTGYSSLSYLSQLPFHGLKIDQSFVRKIPAHPSETQIVTTILALARGLGMEVVAEGIETAQQYAFLRDRGCE
FGQGNLMSTPQAADAFASLLDRQKASGQRPVHGHETAP

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=442, Percent_Identity=37.7828054298643, Blast_Score=296, Evalue=3e-81,
Organism=Escherichia coli, GI87081921, Length=432, Percent_Identity=33.7962962962963, Blast_Score=231, Evalue=2e-61,
Organism=Escherichia coli, GI226510982, Length=446, Percent_Identity=30.0448430493274, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1790496, Length=252, Percent_Identity=32.5396825396825, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI1787055, Length=275, Percent_Identity=31.2727272727273, Blast_Score=146, Evalue=6e-36,
Organism=Escherichia coli, GI87081845, Length=241, Percent_Identity=37.7593360995851, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1786507, Length=241, Percent_Identity=34.4398340248963, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI87081743, Length=243, Percent_Identity=34.5679012345679, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1788502, Length=248, Percent_Identity=32.258064516129, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1788381, Length=441, Percent_Identity=27.437641723356, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI87081980, Length=268, Percent_Identity=31.7164179104478, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1788849, Length=429, Percent_Identity=26.3403263403263, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI87082096, Length=433, Percent_Identity=24.4803695150115, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87081977, Length=174, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788956, Length=184, Percent_Identity=36.4130434782609, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=30.4878048780488, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI87081881, Length=198, Percent_Identity=34.3434343434343, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1787816, Length=167, Percent_Identity=35.3293413173653, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=32.9479768786127, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081974, Length=158, Percent_Identity=32.2784810126582, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082007, Length=171, Percent_Identity=34.5029239766082, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787262, Length=274, Percent_Identity=24.8175182481752, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787056, Length=158, Percent_Identity=32.2784810126582, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787410, Length=222, Percent_Identity=24.7747747747748, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=29.0123456790123, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1788085, Length=172, Percent_Identity=27.3255813953488, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789650, Length=447, Percent_Identity=20.3579418344519, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 83602; Mature: 83602

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYRILLQVWLGCVFLLAPESDAHAQPVRVGVFENPPIVSAGLDGMPRGISIDVIQLVAQ
CHHHHHHHHHHHHHEEECCCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHH
REGWQVSYVSSPVDDLIGRLERGEIDVLAAIGYSEEYARRLRLSRESLIANWAMIFRRAD
CCCCEEEECCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAIDSLPQLKRRRVALVRGSVQAKALIRLAEQFDAPFKPVYVDDFPAVVRALQERRADAG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHCCCCC
SVNRLFAVEYANQPGVVETAIVFSPVSVHYAAPRSADPALLDALDRHLAELKADTDSVYY
CCCEEEEEEECCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHH
TSLKRWLAAAPDGRLPPWLPWLIGGGGGALLLALAFVVLLRHKVGRQTGELQRRADQLEL
HHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EVEQREQAQRHLNRLAYFDGLTRLPNREAFRLTLSQALRTLNGSGGRLALLFVDVDRLKN
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHCC
VNDGLGHRAGDMLLQQIAGRLQSVLRGHDHLSRFGGDEFVVIVSEIVRDTDAERVAGRLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCHHHHHHHHH
AALAAPVDIGGTQVYTGASIGIALYPEDAESLDGLLKHADTAMYQAKEQGGNRYVFYHAQ
HHHHCCCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECH
QTERAVERLTLDTRLRQALERNELVLHYQPIVELASGRIVGGEALVRWEDPERGLVMPSA
HHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHCCCEECCCEEEEECCCCCCEECCCC
FIPAAEDTGLIVALSDWVLEACCTQLRAWQQQGRAADDLTLSVNISTRQFEGEHLTRAVD
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHCCCHHHHHHHHH
RALARSGLRPDCLELEITENVMLVMTDEVRTCLDALRARGVRLALDDFGTGYSSLSYLSQ
HHHHHCCCCCCCEEEEEECCEEEEEEHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHH
LPFHGLKIDQSFVRKIPAHPSETQIVTTILALARGLGMEVVAEGIETAQQYAFLRDRGCE
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
FGQGNLMSTPQAADAFASLLDRQKASGQRPVHGHETAP
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVYRILLQVWLGCVFLLAPESDAHAQPVRVGVFENPPIVSAGLDGMPRGISIDVIQLVAQ
CHHHHHHHHHHHHHEEECCCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHH
REGWQVSYVSSPVDDLIGRLERGEIDVLAAIGYSEEYARRLRLSRESLIANWAMIFRRAD
CCCCEEEECCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VAIDSLPQLKRRRVALVRGSVQAKALIRLAEQFDAPFKPVYVDDFPAVVRALQERRADAG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHCCCCC
SVNRLFAVEYANQPGVVETAIVFSPVSVHYAAPRSADPALLDALDRHLAELKADTDSVYY
CCCEEEEEEECCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHH
TSLKRWLAAAPDGRLPPWLPWLIGGGGGALLLALAFVVLLRHKVGRQTGELQRRADQLEL
HHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EVEQREQAQRHLNRLAYFDGLTRLPNREAFRLTLSQALRTLNGSGGRLALLFVDVDRLKN
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHHCC
VNDGLGHRAGDMLLQQIAGRLQSVLRGHDHLSRFGGDEFVVIVSEIVRDTDAERVAGRLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCHHHHHHHHH
AALAAPVDIGGTQVYTGASIGIALYPEDAESLDGLLKHADTAMYQAKEQGGNRYVFYHAQ
HHHHCCCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECH
QTERAVERLTLDTRLRQALERNELVLHYQPIVELASGRIVGGEALVRWEDPERGLVMPSA
HHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHCCCEECCCEEEEECCCCCCEECCCC
FIPAAEDTGLIVALSDWVLEACCTQLRAWQQQGRAADDLTLSVNISTRQFEGEHLTRAVD
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHCCCHHHHHHHHH
RALARSGLRPDCLELEITENVMLVMTDEVRTCLDALRARGVRLALDDFGTGYSSLSYLSQ
HHHHHCCCCCCCEEEEEECCEEEEEEHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHH
LPFHGLKIDQSFVRKIPAHPSETQIVTTILALARGLGMEVVAEGIETAQQYAFLRDRGCE
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
FGQGNLMSTPQAADAFASLLDRQKASGQRPVHGHETAP
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]