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The map label for this gene is xanB [H]

Identifier: 74317257

GI number: 74317257

Start: 1301051

End: 1302469

Strand: Direct

Name: xanB [H]

Synonym: Tbd_1239

Alternate gene names: 74317257

Gene position: 1301051-1302469 (Clockwise)

Preceding gene: 74317256

Following gene: 74317258

Centisome position: 44.71

GC content: 66.74

Gene sequence:

>1419_bases
ATGACCATTCATCCAGTGATTCTTTCCGGCGGTTCCGGCACCCGTCTGTGGCCCTTGTCGCGTGCGGCTCTGCCCAAGCA
ACTGCTGCCGCTCGCGAGCGAGCGCAGCCTGCTGCAGGATACGGTCCTCCGGCTCGCCGATTTCCCCGACATGGCGGCGC
CGCTCATGGTGTGCAACGTCGAGCATCGGTTCATGATCGCCGAGCAGATGCGGCAGATCGGGGTCCATCCAAGCGCGATC
GTGCTGGAGCCGGTCGGCCGCAACACCGCGCCTGCGATCGCCGTGGCGGCCCTGCGGCTGTCGCGCGAGGATGCCGACGC
GCTCATGCTGGTGCTGCCGGCCGACCATCTGATCGGCGATATCGCGGCCTTCCACGCTGCCATCACGCGCGCCGCCGACG
CAGCGAAGCACGGCTACCTCGCGACGTTCGGCATCGTGGCCGCGACGCCCGAGACGGGCTACGGCTACATCCGTAAAGGC
GATGCCCTGGCCGAGGCGGCAGGTGCGCACGCGGTCGCCGGCTTCGTCGAGAAGCCCGATCTCGCCACCGCTCAGCAGTA
CGTCGCTTCGGGGGATTATTTCTGGAACAGCGGGATGTTCCTGTTCCGGGCGTCAGATTTCCTCAAGGAGCTCGAGACCC
TGCGGCCGGACATCCTGAGCGCGAGCCGCGCCGCGCTCGATGCCGCGAAGCCGGATCTCGATTTCGTGCGTCTCGACCCC
GTCGCTTTCGAGGCCTGCCCGTCGGAATCGGTCGACTACGCCGTGATGGAGCATACCCGCCGCGCTGCCGTGGTGCCGGC
CGACATCGGGTGGAACGACATCGGCGCCTGGTCGGCGCTGTGGGAGGTCGCCGAGAAGGACGCGGCGGGCAACGCGGTCC
GTGGCGACGTGATGCTGGAGAACGCGGCGAACAACTTCGTCCGCGCCGAGACGCGGATGGTCGCGATGCTCGGCGTGTCG
GATCTCGTCGTCGTCGAGACGGCCGACGTGGTGCTCGTGGCGAACAGGGACCAGGTCCAGGACGTGAAGAAGCTCGTCGA
TCGCCTGAAAGCCGCCAAGCGCTGCGAGCATCTGGTTCACAAGCAGGTCTACCGTCCCTGGGGCTGGTACGAGGGGATCG
ACGGCGGCGACCGCTTCCAGGTCAAGCGCATCATGGTCAAGCCGGGCGAGAAGCTGAGCCTGCAGATGCACCACCATCGT
GCCGAGCACTGGGTGGTCGTCTCGGGGACCGCGAGCGTCACCTGCGGCGACGAGGTTATGCTCCTGGCCGAAAACCAGTC
GACCTACATACCGCTCGGCACCACCCACCGGCTCGAGAACCCCGGCAAGGTCGATCTTCACATGATCGAGGTCCAGTCCG
GCACCTATCTCGGCGAAGACGACATCGTCCGCTTCGAGGACGTCTACAAGCGCGACTAG

Upstream 100 bases:

>100_bases
ACTGCTCGAACTGACGGTAAACTTCGCGTGGCGGCAAGCAGTACGACCCGACGGCAATCCGGCGCGTTCACCCGACAAAA
CCGAACCACGAGCGAGCGAC

Downstream 100 bases:

>100_bases
CCGGAAGTCTGTCCGCTCGTGCGGCAGACGGTCTCGCCGCCCCCGCGTTTTTCCCGCCTCGCTCCCGAAGGGCAGGGGGC
GACTTCCCCAACTCGCGTGT

Product: mannose-1-phosphate guanylyltransferase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MTIHPVILSGGSGTRLWPLSRAALPKQLLPLASERSLLQDTVLRLADFPDMAAPLMVCNVEHRFMIAEQMRQIGVHPSAI
VLEPVGRNTAPAIAVAALRLSREDADALMLVLPADHLIGDIAAFHAAITRAADAAKHGYLATFGIVAATPETGYGYIRKG
DALAEAAGAHAVAGFVEKPDLATAQQYVASGDYFWNSGMFLFRASDFLKELETLRPDILSASRAALDAAKPDLDFVRLDP
VAFEACPSESVDYAVMEHTRRAAVVPADIGWNDIGAWSALWEVAEKDAAGNAVRGDVMLENAANNFVRAETRMVAMLGVS
DLVVVETADVVLVANRDQVQDVKKLVDRLKAAKRCEHLVHKQVYRPWGWYEGIDGGDRFQVKRIMVKPGEKLSLQMHHHR
AEHWVVVSGTASVTCGDEVMLLAENQSTYIPLGTTHRLENPGKVDLHMIEVQSGTYLGEDDIVRFEDVYKRD

Sequences:

>Translated_472_residues
MTIHPVILSGGSGTRLWPLSRAALPKQLLPLASERSLLQDTVLRLADFPDMAAPLMVCNVEHRFMIAEQMRQIGVHPSAI
VLEPVGRNTAPAIAVAALRLSREDADALMLVLPADHLIGDIAAFHAAITRAADAAKHGYLATFGIVAATPETGYGYIRKG
DALAEAAGAHAVAGFVEKPDLATAQQYVASGDYFWNSGMFLFRASDFLKELETLRPDILSASRAALDAAKPDLDFVRLDP
VAFEACPSESVDYAVMEHTRRAAVVPADIGWNDIGAWSALWEVAEKDAAGNAVRGDVMLENAANNFVRAETRMVAMLGVS
DLVVVETADVVLVANRDQVQDVKKLVDRLKAAKRCEHLVHKQVYRPWGWYEGIDGGDRFQVKRIMVKPGEKLSLQMHHHR
AEHWVVVSGTASVTCGDEVMLLAENQSTYIPLGTTHRLENPGKVDLHMIEVQSGTYLGEDDIVRFEDVYKRD
>Mature_471_residues
TIHPVILSGGSGTRLWPLSRAALPKQLLPLASERSLLQDTVLRLADFPDMAAPLMVCNVEHRFMIAEQMRQIGVHPSAIV
LEPVGRNTAPAIAVAALRLSREDADALMLVLPADHLIGDIAAFHAAITRAADAAKHGYLATFGIVAATPETGYGYIRKGD
ALAEAAGAHAVAGFVEKPDLATAQQYVASGDYFWNSGMFLFRASDFLKELETLRPDILSASRAALDAAKPDLDFVRLDPV
AFEACPSESVDYAVMEHTRRAAVVPADIGWNDIGAWSALWEVAEKDAAGNAVRGDVMLENAANNFVRAETRMVAMLGVSD
LVVVETADVVLVANRDQVQDVKKLVDRLKAAKRCEHLVHKQVYRPWGWYEGIDGGDRFQVKRIMVKPGEKLSLQMHHHRA
EHWVVVSGTASVTCGDEVMLLAENQSTYIPLGTTHRLENPGKVDLHMIEVQSGTYLGEDDIVRFEDVYKRD

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=473, Percent_Identity=58.1395348837209, Blast_Score=548, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 51631; Mature: 51499

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIHPVILSGGSGTRLWPLSRAALPKQLLPLASERSLLQDTVLRLADFPDMAAPLMVCNV
CEEEEEEEECCCCCEEEECCHHHCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEECC
EHRFMIAEQMRQIGVHPSAIVLEPVGRNTAPAIAVAALRLSREDADALMLVLPADHLIGD
CHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHH
IAAFHAAITRAADAAKHGYLATFGIVAATPETGYGYIRKGDALAEAAGAHAVAGFVEKPD
HHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEECCCHHHHHCCCHHHHHCCCCCC
LATAQQYVASGDYFWNSGMFLFRASDFLKELETLRPDILSASRAALDAAKPDLDFVRLDP
HHHHHHHHHCCCEEECCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEECC
VAFEACPSESVDYAVMEHTRRAAVVPADIGWNDIGAWSALWEVAEKDAAGNAVRGDVMLE
HHEECCCCCCCCHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEECCEEEE
NAANNFVRAETRMVAMLGVSDLVVVETADVVLVANRDQVQDVKKLVDRLKAAKRCEHLVH
CCCCCHHHHHHHEEEEECCCEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
KQVYRPWGWYEGIDGGDRFQVKRIMVKPGEKLSLQMHHHRAEHWVVVSGTASVTCGDEVM
HHHCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCEEEEEECCEEEEECCEEE
LLAENQSTYIPLGTTHRLENPGKVDLHMIEVQSGTYLGEDDIVRFEDVYKRD
EEECCCCEEEECCCCCCCCCCCCEEEEEEEEECCCEECCCCCCHHHHHHCCC
>Mature Secondary Structure 
TIHPVILSGGSGTRLWPLSRAALPKQLLPLASERSLLQDTVLRLADFPDMAAPLMVCNV
EEEEEEEECCCCCEEEECCHHHCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEECC
EHRFMIAEQMRQIGVHPSAIVLEPVGRNTAPAIAVAALRLSREDADALMLVLPADHLIGD
CHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHH
IAAFHAAITRAADAAKHGYLATFGIVAATPETGYGYIRKGDALAEAAGAHAVAGFVEKPD
HHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEECCCHHHHHCCCHHHHHCCCCCC
LATAQQYVASGDYFWNSGMFLFRASDFLKELETLRPDILSASRAALDAAKPDLDFVRLDP
HHHHHHHHHCCCEEECCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEECC
VAFEACPSESVDYAVMEHTRRAAVVPADIGWNDIGAWSALWEVAEKDAAGNAVRGDVMLE
HHEECCCCCCCCHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEECCEEEE
NAANNFVRAETRMVAMLGVSDLVVVETADVVLVANRDQVQDVKKLVDRLKAAKRCEHLVH
CCCCCHHHHHHHEEEEECCCEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
KQVYRPWGWYEGIDGGDRFQVKRIMVKPGEKLSLQMHHHRAEHWVVVSGTASVTCGDEVM
HHHCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCEEEEEECCEEEEECCEEE
LLAENQSTYIPLGTTHRLENPGKVDLHMIEVQSGTYLGEDDIVRFEDVYKRD
EEECCCCEEEECCCCCCCCCCCCEEEEEEEEECCCEECCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]